Affiliation: University Hospital
- Biliary atresiaChristophe Chardot
Service de Chirurgie Pediatrique, Hopital Cantonal Universitaire de Geneve, Rue Willi Donzé 6, CH 1205 Geneve, Switzerland
Orphanet J Rare Dis 1:28. 2006..Liver transplantation may be needed later if the Kasai operation fails to restore the biliary flow or if cirrhotic complications occur. At present, approximately 90% of BA patients survive and the majority have normal quality of life...
- Total laparoscopic excision of retroperitoneal cystic lymphangiomaBarbara E Wildhaber
Department of Pediatric Surgery, University of Children s Hospital, Geneva, Switzerland
J Laparoendosc Adv Surg Tech A 16:530-3. 2006..Both children remained asymptomatic and no recurrence was observed at 18-month follow-up. Complete laparoscopic excision should be considered as a therapeutic option to treat retroperitoneal cystic lymphangioma...
- Fatal GvHD as a complication of liver transplantation for undetermined fulminant hepatic failure and associated aplastic anemiaMichela G Schäppi
Gastroenterology and Hepatology Unit, Department of Pediatrics, University Hospital of Geneva, Switzerland
Liver Transpl 12:1693-7. 2006..The underlying disease will determine the choice of immunosuppressive treatment, especially in case of development of GvHD caused by the transplanted lymphocytes inhabiting the donor liver...
- Cure of multifocal panhepatic hepatoblastoma: is liver transplantation always necessary?Reto Marc Baertschiger
Pediatric Surgery Unit, University of Geneva Children s Hospital, 1211 Geneva 4, Switzerland
J Pediatr Surg 45:1030-6. 2010..This procedure is no longer recommended because of the risk of persistent viable tumor cells in the hepatic remnant. We report our experience with conservative surgery in such cases...
- Focal ischemic necrosis in advanced biliary atresia cirrhosisBarbara E Wildhaber
Department of Pediatric Surgery, University Hospital of Geneva, Geneva, Switzerland
Pediatr Transplant 12:487-91. 2008..Because of precarious hepatic blood supply in such patients, close monitoring of portal and diastolic arterial flows is recommended...
- Severe autoimmune hemolytic anemia in a liver transplanted childMichela G Schäppi
Division of Paediatric Gastroenterology and Transplantation, Children s Hospital of Geneva, Geneva, Switzerland
Pediatr Transplant 12:809-12. 2008..In this report, the etiologies of HA occurring in post-transplant pediatric patients are reviewed and the different treatment strategies are discussed...
- Outcome in adulthood of biliary atresia: a study of 63 patients who survived for over 20 years with their native liverPanayotis Lykavieris
Service d hépatologie pédiatrique, Hopital de Bicetre, AP HP, Le Kremlin Bicetre, France
Hepatology 41:366-71. 2005..In conclusion, in the long term, less than 18% of infants with biliary atresia who are treated with corrective surgery may avoid liver transplantation, but even these patients require assiduous lifelong care...
- Laparoscopic living donor hepatectomy for liver transplantation in childrenDaniel Cherqui
Department of General and Digestive Surgery, Hôpital Henri Mondor 94010, Creteil, France
Lancet 359:392-6. 2002..Because cadaveric organ donors are in short supply, living donors are increasingly being used in transplantations. We have developed a safe and reproducible method for laparoscopic liver resection...
- Biliary atresia: Swiss national study, 1994-2004Barbara E Wildhaber
University Hospital of Geneva, Switzerland
J Pediatr Gastroenterol Nutr 46:299-307. 2008..To determine the epidemiology of biliary atresia (BA) in Switzerland, the outcome of the children from diagnosis, and the prognostic factors...
- Ex vivo lentivirus transduction and immediate transplantation of uncultured hepatocytes for treating hyperbilirubinemic Gunn ratTuan Huy Nguyen
Department of Microbiology and Molecular Medicine, University of Geneva Medical Center, Geneva, Switzerland, and Service de biochimie, Hopital Saint Joseph, Paris, France
Transplantation 82:794-803. 2006..Here, we evaluated the SLIT approach in Gunn rats, the animal model for Crigler-Najjar syndrome type 1, a defect in bilirubin UDP-glucuronosyltransferase (BUGT)...
- Prognostic value of portal pressure at the time of Kasai operation in patients with biliary atresiaMatthieu Duché
Paediatric Surgery, Hepatology, Intensive Care, Pathology and Radiology Units, Bicetre University Hospital, Paris, France
J Pediatr Gastroenterol Nutr 43:640-5. 2006..To examine the prognostic value of portal pressure at the time of Kasai operation in patients with biliary atresia (BA)...
- Management of patients with biliary atresia in France: results of a decentralized policy 1986-2002Marie-Odile Serinet
From the French Observatory of Biliary Atresia, , Le Kremlin, , France
Hepatology 44:75-84. 2006..The early success rate of the Kasai operation remains inferior in the centers with limited caseloads in France, leading to a greater need for LTs in infancy and early childhood...
- Prognosis of biliary atresia: what can be further improved?Christophe Chardot
J Pediatr 148:432-5. 2006
- Long-term outcome of pediatric liver transplantation for biliary atresia: a 10-year follow-up in a single centerVirginie Fouquet
Department of Pediatric Surgery, , , France
Liver Transpl 11:152-60. 2005..In conclusion, we discovered that a good long-term survival could be achieved after liver transplantation for BA, with a 82% survival rate at 10 years with normal scholastic studies in the majority of recipients...
- Treatment for biliary atresia in 2003Christophe Chardot
J Pediatr Gastroenterol Nutr 37:407-8. 2003
- Surgical necrotizing enterocolitis: are intestinal lesions more severe in infants with low birth weight?Christophe Chardot
Pediatric Surgery Unit, Centre Hospitalier Universitaire de Bicetre, Le Kremlin Bicetre, France
J Pediatr Surg 38:167-72. 2003..This study examines whether the intestinal lesions of necrotizing enterocolitis (NEC) in infants undergoing surgery are more severe in patients with extremely low birth weight (BW)...
- Therapy for acute rejection in pediatric organ transplant recipientsDominique Debray
Paediatric Hepatology Unit, , , France
Paediatr Drugs 5:81-93. 2003..Detransplantation or retransplantation may, in some instances, be preferable to severe infectious or tumoral complications...
- Efficacy and pharmacokinetics of tacrolimus oral suspension in pediatric liver transplant recipientsRaymond Reding
Pediatric Liver Transplant Program andHospital Pharmacy, Saint Luc University Clinics, Universite Catholique de Louvain, Brussels, Belgium
Pediatr Transplant 6:124-6. 2002..55%, respectively). Accordingly, the use of OST may constitute an alternative option for tacrolimus administration in low body weight organ recipients, to allow dosage titration in the early post-transplant weeks...
- Living-related liver transplantation and vena cava reconstruction after total hepatectomy including the vena cava for hepatoblastomaChristophe Chardot
Centre Hospitalier Universitaire de Bicetre, 78 rue du General Leclerc, F 94275 Le Kremlin Bicetre, France
Transplantation 73:90-2. 2002..Because the liver graft procured by living donation has no IVC, a reconstruction of the recipient IVC is needed. We report our experience with living-related liver transplantation (LRLT) and IVC replacement in such cases...