Alexandra Calmy

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. pmc Higher memory responses in HIV-infected and kidney transplanted patients than in healthy subjects following priming with the pandemic vaccine
    Claire Anne Siegrist
    Department of Pathology Immunology and Paediatrics, Centre for Vaccinology, University Hospitals of Geneva and Faculty of Medicine, University of Geneva, Geneva, Switzerland
    PLoS ONE 7:e40428. 2012
  2. doi request reprint Long-term HIV infection and antiretroviral therapy are associated with bone microstructure alterations in premenopausal women
    A Calmy
    Division of Infectious Diseases, HIV Unit, Department of Internal Medicine Specialties, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland
    Osteoporos Int 24:1843-52. 2013
  3. doi request reprint Strong serological responses and HIV RNA increase following AS03-adjuvanted pandemic immunization in HIV-infected patients
    A Calmy
    Division of Infectious Diseases, HIV Unit, Department of Internal Medicine, University Hospitals of Geneva, Switzerland
    HIV Med 13:207-18. 2012
  4. pmc Hepatotoxicity and effectiveness of a Nevirapine-based antiretroviral therapy in HIV-infected patients with or without viral hepatitis B or C infection in Cameroon
    Jules B Tchatchueng Mbougua
    Institut de Recherche pour le Developpement, University Montpellier 1, UMR 145, Montpellier, France
    BMC Public Health 10:105. 2010
  5. pmc When to start antiretroviral therapy in resource-limited settings: a human rights analysis
    Nathan Ford
    Medecins Sans Frontieres, Cape Town, South Africa
    BMC Int Health Hum Rights 10:6. 2010
  6. pmc Reduction of missed appointments at an urban primary care clinic: a randomised controlled study
    Noelle Junod Perron
    Division of Primary Care, Department of Community Medicine and Primary Care, Geneva University Hospitals, Geneva, Switzerland
    BMC Fam Pract 11:79. 2010
  7. ncbi request reprint A new era of antiretroviral drug toxicity
    Alexandra Calmy
    Geneva University Hospital, HIV Unit, Geneva, Switzerland
    Antivir Ther 14:165-79. 2009
  8. doi request reprint Association of alcohol consumption and HIV surrogate markers in participants of the swiss HIV cohort study
    Anna Conen
    Division of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital Aarau, Aarau, Switzerland Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland Clinic for Infectious Diseases, University Hospital Berne, University of Berne, Berne, Switzerland Division of Infectious Diseases and Hospital Epidemiology, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland Division of Infectious Diseases and Hospital Epidemiology, University Hospital Geneva, University of Geneva, Geneva, Switzerland Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland Division of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St Gallen, St Gallen, Switzerland Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland and Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Basel, Switzerland
    J Acquir Immune Defic Syndr 64:472-8. 2013
  9. doi request reprint Risk of cardiovascular events and blood pressure control in hypertensive HIV-infected patients: Swiss HIV Cohort Study (SHCS)
    Reto Nuesch
    Division of Infectious Diseases, Hirslanden Klinik St Anna, Lucerne, Switzerland Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland Division of Infectious Diseases, Regional Hospital of Lugano, Lugano, Switzerland Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland Division of Infectious Diseases, University Hospital Lausanne, Lausanne, Switzerland Division of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital of St Gallen, St Gallen, Switzerland Division of Infectious Diseases, University Hospital Bern and University of Bern, Bern, Switzerland and Division of Infectious Diseases, University Hospital of Geneva, Geneva, Switzerland
    J Acquir Immune Defic Syndr 62:396-404. 2013
  10. doi request reprint Safety and efficacy of once-daily nevirapine dosing: a multicohort study
    Alexandra Calmy
    Division of Infectious Disease HIV unit, University Hospital Geneva, Geneva, Switzerland
    Antivir Ther 14:931-8. 2009

Detail Information

Publications27

  1. pmc Higher memory responses in HIV-infected and kidney transplanted patients than in healthy subjects following priming with the pandemic vaccine
    Claire Anne Siegrist
    Department of Pathology Immunology and Paediatrics, Centre for Vaccinology, University Hospitals of Geneva and Faculty of Medicine, University of Geneva, Geneva, Switzerland
    PLoS ONE 7:e40428. 2012
    ..Memory responses require immune competence. We assessed the influence of priming with AS03-adjuvanted pandemic vaccine (Pandemrix®) on memory responses of HIV patients, kidney recipients (SOT) and healthy controls (HC)...
  2. doi request reprint Long-term HIV infection and antiretroviral therapy are associated with bone microstructure alterations in premenopausal women
    A Calmy
    Division of Infectious Diseases, HIV Unit, Department of Internal Medicine Specialties, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland
    Osteoporos Int 24:1843-52. 2013
    ..Premenopausal eumenorrheic HIV-positive women displayed trabecular and cortical microstructure alterations, which could contribute to increased bone fragility in those patients...
  3. doi request reprint Strong serological responses and HIV RNA increase following AS03-adjuvanted pandemic immunization in HIV-infected patients
    A Calmy
    Division of Infectious Diseases, HIV Unit, Department of Internal Medicine, University Hospitals of Geneva, Switzerland
    HIV Med 13:207-18. 2012
    ..We aimed to determine the antibody responses and effect on viral load of the AS03-adjuvanted pandemic H1N1 vaccine in HIV-infected patients...
  4. pmc Hepatotoxicity and effectiveness of a Nevirapine-based antiretroviral therapy in HIV-infected patients with or without viral hepatitis B or C infection in Cameroon
    Jules B Tchatchueng Mbougua
    Institut de Recherche pour le Developpement, University Montpellier 1, UMR 145, Montpellier, France
    BMC Public Health 10:105. 2010
    ....
  5. pmc When to start antiretroviral therapy in resource-limited settings: a human rights analysis
    Nathan Ford
    Medecins Sans Frontieres, Cape Town, South Africa
    BMC Int Health Hum Rights 10:6. 2010
    ....
  6. pmc Reduction of missed appointments at an urban primary care clinic: a randomised controlled study
    Noelle Junod Perron
    Division of Primary Care, Department of Community Medicine and Primary Care, Geneva University Hospitals, Geneva, Switzerland
    BMC Fam Pract 11:79. 2010
    ..The aim of this study was to test the effectiveness of a sequential intervention reminding patients of their upcoming appointment and to identify the profile of patients missing their appointments...
  7. ncbi request reprint A new era of antiretroviral drug toxicity
    Alexandra Calmy
    Geneva University Hospital, HIV Unit, Geneva, Switzerland
    Antivir Ther 14:165-79. 2009
    ..We review life-threatening adverse events, adverse events of new investigational or recently marketed drugs, adverse events with a genetic component and tissue-specific adverse events of fat, heart, bone, kidney and liver...
  8. doi request reprint Association of alcohol consumption and HIV surrogate markers in participants of the swiss HIV cohort study
    Anna Conen
    Division of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital Aarau, Aarau, Switzerland Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland Clinic for Infectious Diseases, University Hospital Berne, University of Berne, Berne, Switzerland Division of Infectious Diseases and Hospital Epidemiology, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland Division of Infectious Diseases and Hospital Epidemiology, University Hospital Geneva, University of Geneva, Geneva, Switzerland Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland Division of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St Gallen, St Gallen, Switzerland Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland and Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, Basel, Switzerland
    J Acquir Immune Defic Syndr 64:472-8. 2013
    ..The authors investigated the association between self-reported alcohol consumption and HIV surrogate markers in both treated and untreated individuals...
  9. doi request reprint Risk of cardiovascular events and blood pressure control in hypertensive HIV-infected patients: Swiss HIV Cohort Study (SHCS)
    Reto Nuesch
    Division of Infectious Diseases, Hirslanden Klinik St Anna, Lucerne, Switzerland Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland Division of Infectious Diseases, Regional Hospital of Lugano, Lugano, Switzerland Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland Division of Infectious Diseases, University Hospital Lausanne, Lausanne, Switzerland Division of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital of St Gallen, St Gallen, Switzerland Division of Infectious Diseases, University Hospital Bern and University of Bern, Bern, Switzerland and Division of Infectious Diseases, University Hospital of Geneva, Geneva, Switzerland
    J Acquir Immune Defic Syndr 62:396-404. 2013
    ..We modeled blood pressure over time and the risk of cardiovascular events in hypertensive HIV-infected individuals...
  10. doi request reprint Safety and efficacy of once-daily nevirapine dosing: a multicohort study
    Alexandra Calmy
    Division of Infectious Disease HIV unit, University Hospital Geneva, Geneva, Switzerland
    Antivir Ther 14:931-8. 2009
    ..Nevirapine (NVP) is often prescribed once daily in clinical practice in combination with a once daily nucleoside backbone. We investigated the relationship of NVP dosing with safety and efficacy...
  11. doi request reprint Adverse events associated with nevirapine use in pregnancy: a systematic review and meta-analysis
    Nathan Ford
    Medecins Sans Frontieres, Geneva, Switzerland
    AIDS 27:1135-43. 2013
    ..We conducted a systematic review and meta-analysis of severe adverse events in HIV-positive women who initiated NVP while pregnant...
  12. doi request reprint Impact of highly active antiretroviral therapy on the molecular epidemiology of newly diagnosed HIV infections
    Juan Ambrosioni
    Laboratory of Virology, Department of Genetics and Laboratory Medicine, University Hospital, Geneva, Switzerland
    AIDS 26:2079-86. 2012
    ..To evaluate HIV-1 transmission trends and the impact of highly active antiretroviral therapy (HAART) on newly diagnosed HIV infections in Geneva, Switzerland...
  13. ncbi request reprint HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial
    Alexandra Calmy
    HIV Unit, Geneva University Hospital, 15 rue Micheli Du Crest, Geneva 1205, Switzerland
    AIDS 23:929-39. 2009
    ..We investigated whether HIV replication modified the levels of these proteins in a combination antiretroviral therapy (cART) interruption trial...
  14. ncbi request reprint Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysis
    Nathan Ford
    aHIV Department, World Health Organization, Geneva, Switzerland bEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, Maryland, USA cDepartment of Infectious Disease Epidemiology, Imperial College London, London, UK dHIV AIDS Unit, Infectious Disease Service, Geneva University Hospital eMédecins Sans Frontières, Geneva, Switzerland
    AIDS 28:S123-31. 2014
    ..The objective of this review is to update evidence on efavirenz safety in HIV-infected pregnant women to inform revision of the 2013 WHO guidelines for antiretroviral therapy in low and middle-income countries...
  15. ncbi request reprint HIV viral load monitoring in resource-limited regions: optional or necessary?
    Alexandra Calmy
    Medecins Sans Frontieres, Access to Medicines Campaign, Geneva, 1211, Switzerland
    Clin Infect Dis 44:128-34. 2007
    ..Rather than considering viral load data to be an unaffordable luxury, efforts should be made to ensure that viral load testing becomes affordable, simple, and easy to use in resource-limited settings...
  16. ncbi request reprint Clustering of HCV coinfections on HIV phylogeny indicates domestic and sexual transmission of HCV
    Roger D Kouyos
    Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Laboratory of Virology, University Hospital Geneva, Geneva, Switzerland, Division of Immunology and Allergy, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland, Department Biomedicine, University of Basel, Basel, Switzerland, Division of Infectious Diseases, Geneva University Hospital, Geneva, Division of Immunology, University Hospital Lausanne, Lausanne, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland and Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland
    Int J Epidemiol 43:887-96. 2014
    ..HCV coinfection remains a major cause of morbidity and mortality among HIV-infected individuals and its incidence has increased dramatically in HIV-infected men who have sex with men(MSM)...
  17. pmc Preferred antiretroviral drugs for the next decade of scale up
    Isabelle Andrieux-Meyer
    Medecins Sans Frontieres, Geneva, Switzerland
    J Int AIDS Soc 15:17986. 2012
    ..This commentary reviews recommendations made in an expert consultation on treatment scale up in resource-limited settings...
  18. doi request reprint Health perceptions of African HIV-infected patients and their physicians
    Melissa I Dominicé Dao
    Geneva University Hospitals, Community Medicine and Primary Care Department, Geneva, Switzerland
    Patient Educ Couns 80:185-90. 2010
    ....
  19. doi request reprint Infrequent replication of parvovirus B19 and erythrovirus genotypes 2 and 3 among HIV-infected patients with chronic anemia
    Tristan Ferry
    Geneva University Hospital, Geneva, Switzerland
    Clin Infect Dis 50:115-8. 2010
    ..Sixteen patients had circulating DNA, with no apparent clinical impact. Erythrovirus-associated anemia is an extremely rare event in HIV-infected patients...
  20. doi request reprint Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysis
    Nathan Ford
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    AIDS 25:2301-4. 2011
    ..85 (95% CI 0.61-1.20). One neural tube defect was observed (myelomeningocele), giving an incidence of 0.07% (95% CI 0.002-0.39)...
  21. pmc Review of the safety, efficacy, and pharmacokinetics of elvitegravir with an emphasis on resource-limited settings
    Janice Soo Fern Lee
    Medecins Sans Frontieres, Geneva University Hospital, Geneva, Switzerland
    HIV AIDS (Auckl) 4:5-15. 2012
    ..Clinical trials addressing specific challenges encountered in resources-limited settings should be encouraged...
  22. pmc HIV treatment for prevention
    Juan Ambrosioni
    HIV Unit, Department of Infectious Diseases, University of Geneva Hospitals, Geneva, Switzerland
    J Int AIDS Soc 14:28. 2011
    ..This will lead to a decrease in HIV transmission while "test-and-treat" is fully explored in prospective clinical trials...
  23. ncbi request reprint Glitazones in lipodystrophy syndrome induced by highly active antiretroviral therapy
    Alexandra Calmy
    Division of aInfectious Diseases, Hopital Cantonal Universitaire, Geneva, Switzerland
    AIDS 17:770-2. 2003
  24. pmc Mean CD4 cell count changes in patients failing a first-line antiretroviral therapy in resource-limited settings
    Alexandra Calmy
    HIV Unit, Geneva University Hospital, Geneva, Switzerland
    BMC Infect Dis 12:147. 2012
    ..We assessed the impact of on-going HIV-RNA replication on CD4 cell count slopes in patients treated with a first-line combination ART...
  25. pmc The first decade of antiretroviral therapy in Africa
    Nathan Ford
    Medecins Sans Frontieres, Geneva, Switzerland
    Global Health 7:33. 2011
    ....
  26. pmc Safety, efficacy, and pharmacokinetics of rilpivirine: systematic review with an emphasis on resource-limited settings
    Nathan Ford
    Medecins Sans Frontieres, Geneva, Switzerland
    HIV AIDS (Auckl) 3:35-44. 2011
    ..These characteristics make rilpivirine an attractive drug for resource-limited settings. Future research should assess the potential to improve robustness and assess the clinical significance of interaction with antituberculosis drugs...
  27. pmc Driving a decade of change: HIV/AIDS, patents and access to medicines for all
    Ellen t Hoen
    Medicines Patent Pool Initiative, UNITAID Secretariat, Geneva, Switzerland
    J Int AIDS Soc 14:15. 2011
    ..Governments must live up to their obligations to protect access to medicines as a fundamental component of the human right to health...