Pascal Bucher

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi [Patient's point of view on surgical innovations: for less traumatic surgery and enhanced recovery]
    P Bucher
    Service de Chirurgie Viscerale, Departement de Chirurgie, HUG, 1211 Geneve 14
    Rev Med Suisse 6:1292-7. 2010
  2. ncbi Totally intracorporeal laparoscopic colorectal anastomosis using circular stapler
    Pascal Bucher
    Visceral Surgery, Department of Surgery, Geneva University Hospital, 24, Rue Micheli du Crest, 1211, Geneva 14, Switzerland
    Surg Endosc 22:1278-82. 2008
  3. ncbi [Diabetes Type I therapy through transplantation]
    P Bucher
    Departement de Chirurgie, Service de chirurgie viscérale et de transplantation, Hopitaux Universitaires de Geneve, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Ann Chir 130:374-83. 2005
  4. doi Single port access laparoscopic cholecystectomy (with video)
    Pascal Bucher
    Department of Surgery, University Hospital Geneva, 24 Rue Micheli du Crest, 1211 Geneva, Switzerland
    World J Surg 33:1015-9. 2009
  5. ncbi Long-term results of radical resection for locally advanced duodenal adenocarcinoma
    Pascal Bucher
    Clinic of Visceral and Transplantation Surgery, Department of Surgery University Hospital Geneva, Switzerland
    Hepatogastroenterology 52:1727-9. 2005
  6. ncbi Mechanical bowel preparation for elective colorectal surgery: a meta-analysis
    Pascal Bucher
    Clinic of Visceral and Transplantation Surgery, Department of Surgery and Division of Medical Statistics, Geneva University Hospital, Geneva, Switzerland
    Arch Surg 139:1359-64; discussion 1365. 2004
  7. doi Transumbilical single incision laparoscopic sigmoidectomy for benign disease
    P Bucher
    Department of Surgery, University Hospital Geneva, 1211, Geneva, Switzerland
    Colorectal Dis 12:61-5. 2010
  8. doi Transumbilical single-incision laparoscopic intracorporeal anastomosis for gastrojejunostomy: case report
    Pascal Bucher
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Surg Endosc 23:1667-70. 2009
  9. ncbi [Scarless surgery: reality through umbilical laparoendoscopic single site surgery (LESS)?]
    P Bucher
    Service de Chirurgie Viscerale, Departement de Chirurgie, HUG, 1211 Geneve
    Rev Med Suisse 5:1412-5. 2009
  10. ncbi [Gastrointestinal stromal tumors (GIST)]
    P Bucher
    Service de Chirurgie Viscerale, Departement de Chirurgie, HUG, 1211 Geneve 14
    Rev Med Suisse 4:1567-70. 2008

Detail Information

Publications86

  1. ncbi [Patient's point of view on surgical innovations: for less traumatic surgery and enhanced recovery]
    P Bucher
    Service de Chirurgie Viscerale, Departement de Chirurgie, HUG, 1211 Geneve 14
    Rev Med Suisse 6:1292-7. 2010
    ..It is our job, to foresee the future of surgery in accordance with health care system needs and patients expectation for adequate implementation of these innovations...
  2. ncbi Totally intracorporeal laparoscopic colorectal anastomosis using circular stapler
    Pascal Bucher
    Visceral Surgery, Department of Surgery, Geneva University Hospital, 24, Rue Micheli du Crest, 1211, Geneva 14, Switzerland
    Surg Endosc 22:1278-82. 2008
    ..We report a new laparoscopic technique for totally intracorporeal colorectal circular anastomosis (TLCCA) using a circular stapler...
  3. ncbi [Diabetes Type I therapy through transplantation]
    P Bucher
    Departement de Chirurgie, Service de chirurgie viscérale et de transplantation, Hopitaux Universitaires de Geneve, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Ann Chir 130:374-83. 2005
    ..It could be done either through pancreas or islet of Langerhans transplantation. In this paper, we review actual knowledge regarding these two types of transplantations...
  4. doi Single port access laparoscopic cholecystectomy (with video)
    Pascal Bucher
    Department of Surgery, University Hospital Geneva, 24 Rue Micheli du Crest, 1211 Geneva, Switzerland
    World J Surg 33:1015-9. 2009
    ..We report a technique of umbilical SPA cholecystectomy using standard laparoscopic instruments and complying with conventional surgical principle and technique of minimally invasive cholecystectomy...
  5. ncbi Long-term results of radical resection for locally advanced duodenal adenocarcinoma
    Pascal Bucher
    Clinic of Visceral and Transplantation Surgery, Department of Surgery University Hospital Geneva, Switzerland
    Hepatogastroenterology 52:1727-9. 2005
    ..Duodenal adenocarcinomas are uncommon tumors characterized by non-specific symptoms and late diagnosis. The objective of this study was to assess long-term results of locally advanced duodenal adenocarcinoma treated by surgical resection...
  6. ncbi Mechanical bowel preparation for elective colorectal surgery: a meta-analysis
    Pascal Bucher
    Clinic of Visceral and Transplantation Surgery, Department of Surgery and Division of Medical Statistics, Geneva University Hospital, Geneva, Switzerland
    Arch Surg 139:1359-64; discussion 1365. 2004
    ..There is little scientific evidence to support the routine practice of mechanical bowel preparation (MBP) before elective colorectal surgery in order to minimize the risk of postoperative septic complications...
  7. doi Transumbilical single incision laparoscopic sigmoidectomy for benign disease
    P Bucher
    Department of Surgery, University Hospital Geneva, 1211, Geneva, Switzerland
    Colorectal Dis 12:61-5. 2010
    ..We report here the first clinical transumbilical SILS sigmoidectomy for benign disease...
  8. doi Transumbilical single-incision laparoscopic intracorporeal anastomosis for gastrojejunostomy: case report
    Pascal Bucher
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Surg Endosc 23:1667-70. 2009
    ..The authors report the first transumbilical single-incision laparoscopic intracorporeal anastomosis for gastrojejunostomy...
  9. ncbi [Scarless surgery: reality through umbilical laparoendoscopic single site surgery (LESS)?]
    P Bucher
    Service de Chirurgie Viscerale, Departement de Chirurgie, HUG, 1211 Geneve
    Rev Med Suisse 5:1412-5. 2009
    ..We, now, have to control its evolution to build a safe and reasonable future for minimally invasive surgery combining patients' desire and safety, populations needs...
  10. ncbi [Gastrointestinal stromal tumors (GIST)]
    P Bucher
    Service de Chirurgie Viscerale, Departement de Chirurgie, HUG, 1211 Geneve 14
    Rev Med Suisse 4:1567-70. 2008
    ..The development of tyrosine kinase inhibitors has changed the management of unresectable GIST. One of them, imatinib mesylate, has been proved to improve survival of metastatic GIST. This paper reviews literature data on GIST...
  11. ncbi Surgical treatment of appendiceal adenocarcinoid (goblet cell carcinoid)
    Pascal Bucher
    Clinic of Visceral and Transplantation Surgery, Department of Surgery, University Hospital Geneva, 24 Rue Micheli du Crest, Geneva 14, 1211 Switzerland
    World J Surg 29:1436-9. 2005
    ..The risk for developing colorectal adenocarcinoma seems to be extremely high in patients treated for appendiceal adenocarcinoid and warrants close follow-up with colonoscopic screening...
  12. ncbi Results of conservative treatment for perforated gastroduodenal ulcers in patients not eligible for surgical repair
    Pascal Bucher
    Clinic of Visceral Surgery, Department of Surgery, Geneva University Hospital, Geneva, Switzerland
    Swiss Med Wkly 137:337-40. 2007
    ..However, its use in patients not eligible for surgical repair has not been supported. The aim of this study is to evaluate the results of conservative treatment in these patients in the era of proton pump inhibitor...
  13. ncbi Long-term results of surgical treatment of Vater's ampulla neoplasms
    Pascal Bucher
    Visceral and Transplantation Surgery Clinic, Department of Surgery, University Hospital Geneva, Switzerland
    Hepatogastroenterology 54:1239-42. 2007
    ..Vater's ampulla neoplasms account for 30% of resected bilio-pancreatic confluent tumors. Study aim was to review long-term results of surgical treatment for ampullary neoplasms...
  14. ncbi Laparoscopic versus open resection for appendix carcinoid
    P Bucher
    Clinic of Visceral and Transplantation Surgery, Department of Surgery, University Hospital Geneva, 24, Rue Micheli du Crest, 1211, Geneva, 14, Switzerland
    Surg Endosc 20:967-70. 2006
    ..The goal of this study was to compare results of laparoscopic (LAP) versus open (OP) appendectomy for AC according to intend to treat approach...
  15. pmc Spontaneous rupture of a gastrointestinal stromal tumour associated with life-threatening nontraumatic hemoperitoneum
    Pascal Bucher
    Visceral and Transplantation Surgery Clinic, Department of Surgery, Geneva University Hospital, Geneva, Switzerland
    Can J Surg 51:E38-9. 2008
  16. doi Single port access laparoscopic right hemicolectomy
    Pascal Bucher
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Int J Colorectal Dis 23:1013-6. 2008
    ..We report in this paper a new technique of umbilical SPA right hemicolectomy with conventional surgical oncologic principle and technique of minimally invasive colectomy...
  17. ncbi An audit of surgical management of gastrointestinal stromal tumours (GIST)
    P Bucher
    Department of Surgery, Visceral and Transplantation Surgery Clinic, Geneva University Hospital, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Eur J Surg Oncol 32:310-4. 2006
    ..To analyze GIST outcome after primary resection and to determine if a new grading system could adequately predict there prognosis...
  18. ncbi [Scarless surgery: myth or reality through NOTES?]
    P Bucher
    Service de Chirurgie Viscerale, Departement de Chirurgie, HUG, 1211 Geneve 14
    Rev Med Suisse 4:1550-2. 2008
    ..The next decade, will show us if surgery will be performed through NOTES or if minimally invasive surgery will be positively influenced by the technical progress of NOTES to be the most minimally traumatic...
  19. ncbi Morphologic alterations associated with mechanical bowel preparation before elective colorectal surgery: a randomized trial
    Pascal Bucher
    Department of Surgery, Clinic of Visceral and Transplantation Surgery, Geneva, Switzerland
    Dis Colon Rectum 49:109-12. 2006
    ..This study was designed to determine whether mechanical bowel preparation is associated with histologic alterations in the colon...
  20. doi Single-port access laparoscopic radical left colectomy in humans
    Pascal Bucher
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Dis Colon Rectum 52:1797-801. 2009
    ..We report our experience with the first transumbilical single-port access radical left colectomy conforming to surgical oncologic principle and minimally invasive colectomy technique...
  21. doi Minimally invasive necrosectomy for infected necrotizing pancreatitis
    Pascal Bucher
    Department of Surgery, Clinic of Visceral and Transplantation Surgery, Geneva University Hospital, Geneva, Switzerland
    Pancreas 36:113-9. 2008
    ..To evaluate results of single large-port laparoscopic necrosectomy for proven infected necrotizing pancreatitis...
  22. doi Female population perception of conventional laparoscopy, transumbilical LESS, and transvaginal NOTES for cholecystectomy
    Pascal Bucher
    Department of Surgery, University Hospital Geneva, 24 Rue Micheli du Crest, 1211, Geneva, Switzerland
    Surg Endosc 25:2308-15. 2011
    ..This study was designed to evaluate the perception and preference of women regarding conventional laparoscopy, U-LESS, and transvaginal NOTES (TV-NOTES) with particular interest to access perception...
  23. doi Single-port access prosthetic repair for primary and incisional ventral hernia: toward less parietal trauma
    Pascal Bucher
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Surg Endosc 25:1921-5. 2011
    ..This forms the basis for evaluating SPA for prosthetic ventral hernia repair. We report a new SPA technique of ventral hernia repair using working-channel endoscope, standard laparoscopic instruments, and 10-mm port...
  24. ncbi Appendix tumors in the era of laparoscopic appendectomy
    P Bucher
    Department of Surgery, Clinic of Visceral and Transplantation Surgery, University Hospital of Geneva, 24 Rue Micheli du Crest, 1211, Geneva 14, Switzerland
    Surg Endosc 18:1063-6. 2004
    ..The safety of laparoscopic appendectomy for the management of incidentally discovered appendiceal tumors has not yet been established...
  25. ncbi Management of gastrointestinal stromal tumors: from diagnosis to treatment
    Pascal Bucher
    Department of Surgery, Geneva University Hospital, Switzerland
    Swiss Med Wkly 134:145-53. 2004
    ..This paper reviews the literature and our experience of GIST, including: diagnosis, pathology, treatment and prognosis...
  26. ncbi Are there any prognostic factors for small intestinal stromal tumors?
    Pascal Bucher
    Department of Surgery, University Hospital of Geneva, 24, Rue Micheli du Crest, 1211, Geneva 14, Switzerland
    Am J Surg 187:761-6. 2004
    ..Criteria that predict the outcome of small intestinal stromal tumors (SIST) after surgical resection are not clearly established. The aim of the study was to define prognostic criteria for SIST...
  27. doi Population perception of surgical safety and body image trauma: a plea for scarless surgery?
    Pascal Bucher
    Department of Surgery, Clinic of Visceral and Transplantation Surgery, University Hospital Geneva, 24 Rue Micheli du Crest, 1211, Geneva, Switzerland
    Surg Endosc 25:408-15. 2011
    ..While scarless surgery (NOTES and LESS) is gaining increasing popularity, perception of these approaches should be investigated...
  28. ncbi Islet of Langerhans transplantation for the treatment of type 1 diabetes
    P Bucher
    Clinic of Visceral and Transplantation Surgery, Cell Isolation and Transplantation Center, Department of Surgery, Geneva University Hospital, Geneva, Switzerland
    Swiss Surg 9:242-6. 2003
    ..Twenty-one patients have been transplanted in Geneva since 2002. They were five solitary islet transplants, 14 islet after kidney transplants and two simultaneous islet-kidney (SIK) recipients. Insulin independence was achieved in 67%...
  29. ncbi Transplantation of discordant xenogeneic islets using repeated therapy with anti-CD154
    Pascal Bucher
    Surgical Research Unit, Department of Surgery, University Hospital Geneva, 1211 Geneva, Switzerland
    Transplantation 79:1545-52. 2005
    ..Costimulatory blockade has been shown to allow long-term survival of xenogeneic islets. The aim of the present study was to analyze the possibility of xenogeneic islet retransplantation using costimulatory blockade...
  30. ncbi Anti-CD154 mAb treatment but not recipient CD154 deficiency leads to long-term survival of xenogeneic islet grafts
    Gang Mai
    Surgical Research Unit, Department of Surgery, University Hospital Geneva, Switzerland
    Am J Transplant 5:1021-31. 2005
    ..Rejection of xenografts and strong MLR responses in Groups 3 and 4 are possible through efficient activation of alternate pathways of costimulation...
  31. ncbi Impairment of renal function after islet transplant alone or islet-after-kidney transplantation using a sirolimus/tacrolimus-based immunosuppressive regimen
    Axel Andres
    Cell Isolation and Transplantation Center, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland
    Transpl Int 18:1226-30. 2005
    ..Although a specific etiology was not identified, some subsets of patients presented a higher risk for decline of kidney function. Low creatinin clearance, albuminuria and long-established kidney graft were associated with poorer outcome...
  32. ncbi Does mechanical bowel preparation have a role in preventing postoperative complications in elective colorectal surgery?
    Pascal Bucher
    Department of Surgery, Geneva University Hospital, Geneva, Switzerland
    Swiss Med Wkly 134:69-74. 2004
    ..mechanical bowel preparation (MBP) consists of orthograde fluid preparation to clean the bowel. MBP is considered to prevent postoperative complications...
  33. ncbi Microbial surveillance during human pancreatic islet isolation
    Pascal Bucher
    Laboratory for Cell Isolation and Transplantation, Clinic for Visceral and Transplant Surgery, Geneva University Hospital, Geneva, Switzerland
    Transpl Int 18:584-9. 2005
    ..Most microorganisms are eliminated during islet isolation, and de novo contaminations during islet isolation are rare. Pancreas decontamination reduces the risk of infection of the final islet preparation...
  34. doi Learning curve for robot-assisted Roux-en-Y gastric bypass
    Nicolas C Buchs
    Clinic for Visceral and Transplantation Surgery, Department of Surgery, University Hospital of Geneva, Rue Gabriel Perret Gentil, 4, 1211, Geneva 14, Switzerland
    Surg Endosc 26:1116-21. 2012
    ..However, the specific learning curve associated with this new approach remains poorly investigated. This study aimed to evaluate the learning curve for robot-assisted RYGBP...
  35. ncbi Incidence, consequences, and risk factors for anastomotic dehiscence after colorectal surgery: a prospective monocentric study
    Nicolas C Buchs
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Int J Colorectal Dis 23:265-70. 2008
    ..This study was designed to assess the incidence, to observe the consequences, and to identify the risk factors associated with anastomotic leakage after colorectal surgery...
  36. doi Value of performing routine postoperative liquid contrast swallow studies following robot-assisted Roux-en-Y gastric bypass
    Nicolas C Buchs
    Clinic for Visceral and Transplantation Surgery, Department of Surgery, University Hospital of Geneva, Switzerland
    Swiss Med Wkly 142:w13556. 2012
    ..According to the introduction of robotic technology associated with a hypothetical decrease of anastomotic complications, we aim to assess the validity and cost effectiveness of early routine UGI following robot-assisted RYGB...
  37. ncbi Proximal location of colon cancer is a risk factor for development of metachronous colorectal cancer: a population-based study
    Pascal Gervaz
    Department of Visceral Surgery, University Hospital Geneva, 24 Rue Micheli du Crest, 1211 Geneva, Switzerland
    Dis Colon Rectum 48:227-32. 2005
    ..This study was undertaken to assess the incidence of 1) metachronous colorectal cancer and 2) subsequent extracolonic cancers, in relation to the location (proximal or distal to the splenic flexure) of the first primary colorectal tumor...
  38. ncbi Lessons learned from one thousand consecutive colonic resections in a teaching hospital
    Nicolas C Buchs
    Department of Surgery, University Hospital Geneva, 24 Rue Micheli du Crest, CH 1211 Geneva, Switzerland
    Swiss Med Wkly 137:259-64. 2007
    ..Elective colectomies are standard procedures carrying below 1% mortality; by contrast, emergency colonic resections remain surgical challenges in compromised and/or elderly patients and are associated with high complication rates...
  39. ncbi Macrophage depletion prolongs discordant but not concordant islet xenograft survival
    Axel Andres
    Surgical Research Unit, Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Transplantation 79:543-9. 2005
    ..In vivo, we analyzed the effect of macrophage depletion on concordant and discordant islet xenograft survival to assess in which combination this strategy can be used as therapeutic tool...
  40. pmc Segmental duodenectomy for gastrointestinal stromal tumor of the duodenum
    Nicolas Christian Buchs
    Department of Surgery, University Hospital Geneva, 24 Rue Micheli du Crest, 1211, Geneva, Switzerland
    World J Gastroenterol 16:2788-92. 2010
    ..To evaluate the results of segmental duodenectomy (SD) and pancreaticoduodenectomy (PD) for duodenal gastrointestinal stromal tumor (GIST) and help clinicians with surgical management...
  41. doi Robotic single-port cholecystectomy using a new platform: initial clinical experience
    Philippe Morel
    Division of Digestive Surgery, Department of Surgery, University Hospital Geneva, 4, rue Gabrielle Perret Gentil, 1211, Geneva, Switzerland
    J Gastrointest Surg 15:2182-6. 2011
    ..While manual single-port laparoscopy is technically challenging, a newly approved robotic platform used with the da Vinci Si System (Intuitive Surgical, Sunnyvale, CA, USA) might overcome some of the difficulties of this technique...
  42. pmc Phlegmonous colitis: another source of sepsis in cirrhotic patients?
    Thomas Holzer
    Department of Surgery, Geneva University Hospital and Medical School, 1211 Geneva, Switzerland
    BMC Gastroenterol 9:94. 2009
    ..The clinical relevance of phlegmonous colitis (PC), a rare autopsy finding in cirrhotic patients, is poorly documented. We postulated that PC might be a source of sepsis in patients with portal hypertensive colopathy (PHC)...
  43. pmc Results of emergency Hartmann's operation for obstructive or perforated left-sided colorectal cancer
    Pierre Charbonnet
    Department of Surgery, University Hospital Geneva, Switzerland
    World J Surg Oncol 6:90. 2008
    ..The aim of this study was to assess the surgical (operative mortality), and oncological (long-term survival after curative resection) results of emergency HP for obstructive or perforated left-sided CRC...
  44. ncbi Islet autotransplantation after left pancreatectomy for non-enucleable insulinoma
    Jose Oberholzer
    Department of Surgery, University Hospital of Geneva, Geneva, Switzerland
    Am J Transplant 3:1302-7. 2003
    ..In conclusion, autologous islet transplantation can preserve the insulin secretory reserve after extended left pancreatectomy for the treatment of benign tumors in the pancreatic neck...
  45. doi Robot-assisted oncologic resection for large gastric gastrointestinal stromal tumor: a preliminary case series
    Nicolas C Buchs
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    J Laparoendosc Adv Surg Tech A 20:411-5. 2010
    ..e., close to pylorus or cardia). Its use in oncologic gastric surgery has been poorly defined and has never been reported for GIST...
  46. doi Intra-operative fluorescent cholangiography using indocyanin green during robotic single site cholecystectomy
    Nicolas C Buchs
    Clinic for Visceral and Transplantation Surgery, Department of Surgery, University Hospital of Geneva, Switzerland
    Int J Med Robot 8:436-40. 2012
    ..This paper presents the first report of ICG imaging during a RSSC...
  47. ncbi The duration of postoperative ileus after elective colectomy is correlated to surgical specialization
    Pascal Gervaz
    Department of Surgery, University Hospital of Geneva, Geneva, Switzerland
    Int J Colorectal Dis 21:542-6. 2006
    ..The aim of this study was to measure the role of various clinical determinants on restoration of intestinal function after elective colorectal surgery...
  48. ncbi Assessment of a novel two-component enzyme preparation for human islet isolation and transplantation
    Pascal Bucher
    Cell Isolation and Transplantation Center, Department of Surgery, Geneva University Hospital, Geneva, Switzerland
    Transplantation 79:91-7. 2005
    ..In this study, we have evaluated a new enzyme preparation in which highly purified collagenase can be blended with separately supplied neutral protease in a predetermined ratio...
  49. ncbi Impact of a sirolimus/tacrolimus-based immunosuppressive regimen on kidney function after islet transplantation
    A Andres
    Cell Isolation and Transplantation Center, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland
    Transplant Proc 37:1326-7. 2005
    ..Herein, we analyze the impact of the sirolimus/low-dose tacrolimus-based protocol on kidney function...
  50. ncbi Molecular detection of circulating beta-cells after islet transplantation
    Beate Ritz-Laser
    Diabetes Unit, Department of Internal Medecine, University Hospital Geneva, Geneva, Switzerland
    Diabetes 51:557-61. 2002
    ..This test may allow better estimation of islet cell loss and identification of factors involved in islet graft injury...
  51. doi Value of contrast-enhanced 18F-fluorodeoxyglucose positron emission tomography/computed tomography in detection and presurgical assessment of pancreatic cancer: a prospective study
    Nicolas C Buchs
    Clinic for Visceral and Transplantation Surgery, Department of Surgery, University Hospitals of Geneva, Switzerland
    J Gastroenterol Hepatol 26:657-62. 2011
    ..The aim of this study is to investigate the performance of FDG PET associated with contrast-enhanced CT in detection of pancreatic cancer...
  52. doi Augmented reality and image overlay navigation with OsiriX in laparoscopic and robotic surgery: not only a matter of fashion
    Francesco Volonte
    Visceral and Transplantation Surgery, Department of Surgery, University Hospitals of Geneva, Rue Gabrielle Perret Gentil 4, 1211, Geneva 14, Switzerland
    J Hepatobiliary Pancreat Sci 18:506-9. 2011
    ..Augmented reality techniques, robot assisted operations and computer assisted navigation tools will become increasingly important in surgery and in residents' education...
  53. ncbi Two colons-two cancers: paradigm shift and clinical implications
    Pascal Gervaz
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    J Surg Oncol 88:261-6. 2004
    ..In the future, clinical decision-making regarding adjuvant chemotherapy might be stratified according to the MSI status of cancers located proximally to the splenic flexure...
  54. ncbi A Prospective longitudinal evaluation of quality of life after abdominoperineal resection
    Pascal Gervaz
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    J Surg Oncol 97:14-9. 2008
    ..Abdominoperineal resection (APR) is a disfiguring procedure, frequently associated with significant urogenital dysfunction. The aim of this prospective study was to repeatedly assess quality of life (QoL) 1, 6, and 12 months after APR...
  55. ncbi Human islet allotransplantation with Basiliximab in type I diabetic patients with end-stage renal failure
    J Oberholzer
    Division of Surgical Research, Clinic of Digestive and Transplant Surgery, Department of Surgery, University Hospital of Geneva, Geneva, Switzerland
    Transplant Proc 34:823-5. 2002
  56. doi Transarterial embolization in acute colonic bleeding: review of 11 years of experience and long-term results
    Andrea Rossetti
    Clinic for Visceral Surgery and Transplantation, Department of Surgery, University Hospital of Geneva, Rue Gabrielle Perret Gentil 4, 1211, Geneva, Switzerland
    Int J Colorectal Dis 28:777-82. 2013
    ..The aim of this study is thus to evaluate the short-term and long-term outcomes after selective embolization for colonic bleeding...
  57. doi Laparoscopic treatment of mucinous urachal adenocarcinoma with mucocele
    Marine Oberndoerfer
    Department of Surgery, Clinics of Visceral Surgery, University Hospital Geneva, Geneva, Switzerland
    Surg Laparosc Endosc Percutan Tech 19:e26-8. 2009
    ..Since laparoscopic en bloc resection of the urachus and partial cystectomy, the patient has been healthy and disease-free for 12 months. Modern surgical treatment of urachal adenocarcinoma is discussed in the light of this case...
  58. ncbi Intra-portal injection of 400- microm microcapsules in a large-animal model
    Christian Toso
    Division d Investigations Chirurgicales, Clinique de Chirurgie Digestive et Unité de Transplantation, Hopital Universitaire, 24 Rue Micheli du Crest, 1211 Geneva, Switzerland
    Transpl Int 16:405-10. 2003
    ..Hemodynamic, biological and radiological results are similar to those observed in clinical free-islet transplantation...
  59. ncbi Xenotransplantation: an update on recent progress and future perspectives
    Pascal Bucher
    Surgical Research Unit, Department of Surgery, University Hospital Geneva, Switzerland
    Transpl Int 18:894-901. 2005
    ..As xenotransplantation is moving closer to clinical application, future perspectives must establish guidelines to ensure that future clinical trials are carried out ethically and safely...
  60. ncbi Outcome of surgery for rectal cancer in octogenarians
    Elisabeth Andereggen
    Department of Surgery, University Hospital Geneva, Switzerland
    Swiss Med Wkly 136:185-8. 2006
    ..The aim of this study was to assess the outcome of surgery for rectal cancer in patients 80 years of age or more...
  61. ncbi [Vacuum-assisted abdominal closure: its role in the treatment of complex abdominal and perineal wounds. Experience in 48 patients]
    Y Durmishi
    Departement de Chirurgie, Hopital Universitaire de Geneve, 24 Rue Micheli du Crest, Geneva, Switzerland
    J Chir (Paris) 144:209-13. 2007
    ..Vacuum-assisted closure (VAC) is a promising approach for the management of complex abdominal and perineal wounds. This paper summarizes our experience with this therapeutic modality and demonstrates its efficacity in difficult situations...
  62. ncbi Islet autotransplantation for the prevention of surgical diabetes after extended pancreatectomy for the resection of benign tumors of the pancreas
    T Berney
    Cell Isolation and Transplantation Center, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland
    Transplant Proc 36:1123-4. 2004
    ..The objective of this article is to report a single-center experience with islet autotransplantation after extensive pancreatic resection for benign tumors of the pancreas...
  63. ncbi Islet of Langerhans allogeneic transplantation at the University of Geneva in the steroid free era in islet after kidney and simultaneous islet-kidney transplantations
    T Berney
    Cell Isolation and Transplantation Center, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland
    Transplant Proc 36:1121-2. 2004
    ..We report a single-center experience of islet allogeneic transplantation in islet after kidney (IAK) and simultaneous islet-kidney (SIK) type 1 diabetic recipients using a steroid-free immunosuppressive regimen...
  64. ncbi Robot-assisted gastrectomy for cancer
    N C Buchs
    Department of Surgery, University Hospitals of Geneva, Geneva, Switzerland
    Minerva Gastroenterol Dietol 57:33-42. 2011
    ..Randomized controlled trials with long-term follow up are needed before this promising approach can eventually be generalized...
  65. ncbi [Really so far from fast-track colorectal surgery in senior patients?]
    S Ostermann
    Service de Chirurgie Viscerale, Departement de Chirurgie, HUG, 1211 Geneve 14
    Rev Med Suisse 5:1676-9. 2009
    ..Elective colorectal surgery should be offered to senior patients. However the relative high morbidity rate with standard care prompts us to initiate a specifically designed fast-track protocol in senior patients...
  66. ncbi Randomized clinical trial of mechanical bowel preparation versus no preparation before elective left-sided colorectal surgery
    P Bucher
    Clinic of Visceral and Transplantation Surgery, Department of Surgery, Geneva University Hospital, Geneva 14, Switzerland
    Br J Surg 92:409-14. 2005
    ..The aim of this randomized clinical trial was to compare the outcome of patients who underwent elective left-sided colorectal surgery with or without MBP...
  67. doi Trans-sacral (Kraske) approach for gastrointestinal stromal tumour of the lower rectum: old procedure for a new disease
    P Gervaz
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Colorectal Dis 10:951-2. 2008
    ..Lower rectum GISTs are good indications for the Kraske procedure, and this relatively new disease entity may contribute to the reintroduction of an old procedure into the armamentarium of 21(st) century colorectal surgeons...
  68. ncbi Morbidity associated with intraportal islet transplantation
    P Bucher
    Department of Surgery, Cell Isolation and Transplantation Center, Geneva University Hospital, Geneva, Switzerland
    Transplant Proc 36:1119-20. 2004
    ..Complications associated with intraportal islet infusion have been reported. In this study, we analyzed the relationship between occurrence of complications and islet preparation characteristics/infusion technique...
  69. ncbi Results from percutaneous drainage of Hinchey stage II diverticulitis guided by computed tomography scan
    Y Durmishi
    Department of Surgery, University Hospital Geneva, Rue Micheli du Crest 24, 1211, Geneve, Switzerland
    Surg Endosc 20:1129-33. 2006
    ..The rationale behind this approach is to manage the septic complication conservatively and to follow this later using elective sigmoidectomy with primary anastomosis...
  70. ncbi Factors affecting human islet of Langerhans isolation yields
    C Toso
    Division of Surgical Research, Department of Surgery, University Hospital, University of Geneva, Switzerland
    Transplant Proc 34:826-7. 2002
  71. ncbi Beta cell replacement for the treatment of diabetes
    J Oberholzer
    Department of Surgery, University Hospital, Geneva, Switzerland
    Ann N Y Acad Sci 944:373-87. 2001
    ..In this review we discuss the various key steps in islet transplantation and offer perspectives for future developments in the replacement of insulin-producing beta cells for the treatment of type I diabetes...
  72. ncbi Short-term immunosuppression reduces fibrotic cellular infiltration around barium-M-alginate microbeads injected intraportally
    Z Mathe
    Cell Isolation and Transplantation Center, Geneva University Hospitals, Geneva, Switzerland
    Transplant Proc 36:1199-200. 2004
    ..One of the major barriers affecting the viability of encapsulated islets is pericapsular fibrotic infiltration (PFI). This study aimed to design strategies to reduce PFI around intraportally injected alginate microbeads...
  73. ncbi Phylogenetic disparity influences the predominance of direct over indirect pathway of antigen presentation in islet xenotransplantation
    A Andres
    Surgical Research Unit, Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Transplant Proc 37:463-5. 2005
    ..The aim of this study was to analyze in vitro the predominance of direct or indirect presentation, and in vivo the effect of macrophage depletion on concordant and discordant islet xenograft survival...
  74. ncbi Role of CD40-CD154 pathway in the rejection of concordant and discordant xenogeneic islets
    G Mai
    Surgical Research Unit, Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Transplant Proc 37:460-2. 2005
    ..The aim of the present study was to evaluate the role of recipient CD40 and CD154 in the rejection process of concordant and discordant islet xenotransplantation (Tx)...
  75. ncbi Retransplantation of discordant xenogeneic islets with costimulatory blockade
    P Bucher
    Division of Surgical Research, Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Transplant Proc 36:1201-2. 2004
    ..The aim of the study was to analyze the possibility of xenogeneic islet retransplantation using costimulatory blockade...
  76. ncbi Optimization of neutral protease to collagenase activity ratio for islet of Langerhans isolation
    P Bucher
    Cell Isolation and Transplantation Center, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland
    Transplant Proc 36:1145-6. 2004
    ..The optimal neutral protease to collagenase activity ratio has not been determined for islet isolation. We evaluated a new highly purified collagenase that can be blended with predetermined amounts of neutral protease (NP)...
  77. ncbi Microbial surveillance during human pancreatic islet isolation
    P Bucher
    Cell Isolation and Transplantation Center, Geneva University Hospitals, Geneva, Switzerland
    Transplant Proc 36:1147-8. 2004
    ..The study aim was to investigate the microbiological safety of islet isolation and transplantation...
  78. ncbi Reduction of blood glucose variability in type 1 diabetic patients treated by pancreatic islet transplantation: interest of continuous glucose monitoring
    Laurence Kessler
    Department of Endocrinology, University Hospital, Strasbourg, France
    Diabetes Care 25:2256-62. 2002
    ..To compare the glycemic profiles of patients with type 1 diabetes treated with either an implantable insulin pump or pancreas or islet transplantation by the means of the continuous glucose monitoring system (CGMS; Minimed, Sylmar, CA)...
  79. pmc Should preoperative mechanical bowel preparation be abandoned?
    Pascal Bucher
    Ann Surg 245:662. 2007
  80. ncbi Insulin independence after conversion to tacrolimus and sirolimus-based immunosuppression in islet-kidney recipients
    Christian Toso
    Transplantation 76:1133-4. 2003
  81. ncbi Influence of islet transportation on pancreatic islet allotransplantation in type 1 diabetic patients within the Swiss-French GRAGIL network
    Laurence Kessler
    Department of Endocrinology, University Hospital, Strasbourg, France
    Transplantation 77:1301-4. 2004
    ..The influence of islet transportation on pancreatic islet allotransplantation in type 1 diabetic patients was evaluated within the GRAGIL network...
  82. ncbi Cost analysis of human islet transplantation for the treatment of type 1 diabetes in the Swiss-French Consortium GRAGIL
    Adrienne P Guignard
    Department of Medical Information, Hospices Civils, Lyon, France
    Diabetes Care 27:895-900. 2004
    ..To evaluate the cost of islet transplantation in type 1 diabetic patients with a functional renal graft in a multicenter network...
  83. pmc Activation of human macrophages by allogeneic islets preparations: inhibition by AOP-RANTES and heparinoids
    Severine Sigrist
    Centre Européen d Etude du Diabète, Strasbourg, France
    Immunology 111:416-21. 2004
    ..In conclusion, AOP-RANTES and heparinoids inhibit human macrophage activation and migration induced by islets supernatant...
  84. ncbi Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function
    Kathrin Maedler
    Division of Endocrinology and Diabetes, Department of Medicine, University Hospital, CH 8091 Zurich, Switzerland
    Diabetes 52:726-33. 2003
    ..The deleterious effect of palmitic acid is mediated via formation of ceramide and activation of the apoptotic mitochondrial pathway, whereas Bcl-2 may contribute to the protective effect of monounsaturated fatty acids...
  85. ncbi Notice of duplicate publication: "Mechanical bowel preparation for elective colorectal surgery: a meta-analysis" (Arch Surg. 2004;139:1359-1364)
    Pascal Bucher
    Arch Surg 141:217. 2006
  86. ncbi [New results in allotransplantation of pancreatic islet cells]
    Zoltan Mathe
    Semmelweis Egyetem, Általános Orvostudományi Kar, Transzplantációs és Sebészeti Klinika, Budapest
    Orv Hetil 145:1053-9. 2004
    ..These elements give hope that diabetes might be in the near future treated by islet cell transplantation...