H C Bucher

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. pmc Learning from failure--rationale and design for a study about discontinuation of randomized trials (DISCO study)
    Benjamin Kasenda
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    BMC Med Res Methodol 12:131. 2012
  2. pmc Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections
    Philipp Schuetz
    Department of Internal Medicine, Division of Endocrinology, Diabetes and Clinical Nutrition, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland
    Crit Care 14:R106. 2010
  3. pmc Procalcitonin guided antibiotic therapy and hospitalization in patients with lower respiratory tract infections: a prospective, multicenter, randomized controlled trial
    Philipp Schuetz
    Department of Internal Medicine, Diabetes and Clinical Nutrition, University Hospital Basel, Petersgraben 4, Basel, Switzerland
    BMC Health Serv Res 7:102. 2007
  4. ncbi request reprint [Benefit and pitfalls in the use of data from surrogate endpoint trials for clinical decision making]
    Heiner C Bucher
    Basel Institute for Clinical Epidemiology and Biostatistics, Universitatsspital Basel
    Z Evid Fortbild Qual Gesundhwes 104:230-7; discussion 237-8. 2010
  5. doi request reprint [Surrogate endpoint trials: benefit and pitfalls for clinical decision making]
    H C Bucher
    Basel Institute for Clinical Epidemiology and Biostatistics, Universitatsspital Basel, 4031, Basel, Switzerland
    Internist (Berl) 49:681-7. 2008
  6. doi request reprint CD4+ T cell count recovery in HIV type 1-infected patients is independent of class of antiretroviral therapy
    Nina Khanna
    Division of Infectious Diseases and Hospital Epidemiology, University Hospital, Basel, Switzerland
    Clin Infect Dis 47:1093-101. 2008
  7. pmc Public-health and individual approaches to antiretroviral therapy: township South Africa and Switzerland compared
    Olivia Keiser
    Institute of Social and Preventive Medicine ISPM, University of Bern, Bern, Switzerland
    PLoS Med 5:e148. 2008
  8. doi request reprint Durability and outcome of initial antiretroviral treatments received during 2000--2005 by patients in the Swiss HIV Cohort Study
    Thi Tuyet Nhung Vo
    VCHAP Project, Tropical Disease Hospital, Ho Chi Minh City, Vietnam
    J Infect Dis 197:1685-94. 2008
  9. ncbi request reprint Respiratory symptoms, atopy and bronchial hyperreactivity in professional firefighters
    D Miedinger
    Department of Internal Medicine, University Hospital, 4031 Basel, Switzerland
    Eur Respir J 30:538-44. 2007
  10. ncbi request reprint HAART and the heart: changes in coronary risk factors and implications for coronary risk in men starting antiretroviral therapy
    J A C Sterne
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Intern Med 261:255-67. 2007

Collaborators

Detail Information

Publications20

  1. pmc Learning from failure--rationale and design for a study about discontinuation of randomized trials (DISCO study)
    Benjamin Kasenda
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    BMC Med Res Methodol 12:131. 2012
    ..Currently, little is known regarding the frequency and characteristics of discontinued RCTs...
  2. pmc Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections
    Philipp Schuetz
    Department of Internal Medicine, Division of Endocrinology, Diabetes and Clinical Nutrition, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland
    Crit Care 14:R106. 2010
    ..Measurement of prohormones representing different pathophysiological pathways could enhance risk stratification in patients with community-acquired pneumonia (CAP) and other lower respiratory tract infections (LRTI)...
  3. pmc Procalcitonin guided antibiotic therapy and hospitalization in patients with lower respiratory tract infections: a prospective, multicenter, randomized controlled trial
    Philipp Schuetz
    Department of Internal Medicine, Diabetes and Clinical Nutrition, University Hospital Basel, Petersgraben 4, Basel, Switzerland
    BMC Health Serv Res 7:102. 2007
    ....
  4. ncbi request reprint [Benefit and pitfalls in the use of data from surrogate endpoint trials for clinical decision making]
    Heiner C Bucher
    Basel Institute for Clinical Epidemiology and Biostatistics, Universitatsspital Basel
    Z Evid Fortbild Qual Gesundhwes 104:230-7; discussion 237-8. 2010
    ....
  5. doi request reprint [Surrogate endpoint trials: benefit and pitfalls for clinical decision making]
    H C Bucher
    Basel Institute for Clinical Epidemiology and Biostatistics, Universitatsspital Basel, 4031, Basel, Switzerland
    Internist (Berl) 49:681-7. 2008
    ....
  6. doi request reprint CD4+ T cell count recovery in HIV type 1-infected patients is independent of class of antiretroviral therapy
    Nina Khanna
    Division of Infectious Diseases and Hospital Epidemiology, University Hospital, Basel, Switzerland
    Clin Infect Dis 47:1093-101. 2008
    ....
  7. pmc Public-health and individual approaches to antiretroviral therapy: township South Africa and Switzerland compared
    Olivia Keiser
    Institute of Social and Preventive Medicine ISPM, University of Bern, Bern, Switzerland
    PLoS Med 5:e148. 2008
    ..We compared virologic response, changes to first-line regimens, and mortality in HIV-infected patients starting HAART in South Africa and Switzerland...
  8. doi request reprint Durability and outcome of initial antiretroviral treatments received during 2000--2005 by patients in the Swiss HIV Cohort Study
    Thi Tuyet Nhung Vo
    VCHAP Project, Tropical Disease Hospital, Ho Chi Minh City, Vietnam
    J Infect Dis 197:1685-94. 2008
    ..Little is known about time trends, predictors, and consequences of changes made to antiretroviral therapy (ART) regimens early after patients initially start treatment...
  9. ncbi request reprint Respiratory symptoms, atopy and bronchial hyperreactivity in professional firefighters
    D Miedinger
    Department of Internal Medicine, University Hospital, 4031 Basel, Switzerland
    Eur Respir J 30:538-44. 2007
    ..It remains unclear whether these findings were present at recruitment or developed after joining the workforce...
  10. ncbi request reprint HAART and the heart: changes in coronary risk factors and implications for coronary risk in men starting antiretroviral therapy
    J A C Sterne
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Intern Med 261:255-67. 2007
    ..To estimate changes in coronary risk factors and their implications for coronary heart disease (CHD) rates in men starting highly active antiretroviral therapy (HAART)...
  11. ncbi request reprint Prevalence of risk factors for cardiovascular disease in HIV-infected patients over time: the Swiss HIV Cohort Study
    T R Glass
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Basel, Switzerland
    HIV Med 7:404-10. 2006
    ..We evaluated changes in the prevalence of cardiovascular risk factors (CVRFs) and 10-year risk of CHD in a large cohort of HIV-infected individuals...
  12. ncbi request reprint Response to first protease inhibitor- and efavirenz-containing antiretroviral combination therapy. The Swiss HIV Cohort Study
    A C Friedl
    Division of Infectious Diseases and Hospital Epidemiology, Department of Internal Medicine, University Hospital Zurich, Switzerland
    AIDS 15:1793-800. 2001
    ..The relevance of these observations remains to be determined in studies with longer follow-up...
  13. ncbi request reprint Ritonavir plus saquinavir versus single protease inhibitor therapy in protease inhibitor-naive HIV-infected patients: the Swiss HIV Cohort Study
    H C Bucher
    Basel Center for HIV Research, Internal Medicine Outpatient Clinic University Hospital Basel, Switzerland
    HIV Med 3:247-53. 2002
    ..To compare the response to ritonavir (RTV) plus saquinavir (SQV) with single protease inhibitor (PI) therapies among PI-naive HIV-1 infected individuals...
  14. ncbi request reprint Demographics and prevalent risk factors of chronic subdural haematoma: results of a large single-center cohort study
    H Baechli
    Department of Neurosurgery, University Hospital Basle, Spitalstrasse 21, Basel, Switzerland
    Neurosurg Rev 27:263-6. 2004
    ..The indication for these medications, especially in elderly patients at risk for falls, should be carefully evaluated and controlled...
  15. ncbi request reprint [Evidence-based medicine and patient-doctor relationships]
    H C Bucher
    Klinische Epidemiologie, Universitatsspital Basel
    Praxis (Bern 1994) 94:1521-3. 2005
  16. ncbi request reprint Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV-infection
    M Briel
    University Hospital Basel, Basel Institute for Clinical Epidemiology, Internal Medicine, Hebelstrasse 10, Basel, Switzerland 4031
    Cochrane Database Syst Rev 3:CD006150. 2006
    ..It was suggested that in these patients corticosteroids adjunctive to standard treatment for PCP could prevent the need for mechanical ventilation and decrease mortality...
  17. ncbi request reprint [Evidence-based clinical decision making]
    H C Bucher
    Praxis (Bern 1994) 94:541. 2005
  18. doi request reprint HLA-Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy
    Andri Rauch
    Division of Infectious Diseases, University Hospital Bern and University of Bern, Switzerland
    Clin Infect Dis 46:1921-5. 2008
    ..01, compared with HLA-Bw4 homozygotes). HLA-Bw4 homozygosity appears to predict an impaired CD4 T cell recovery after initiation of combination antiretroviral therapy...
  19. ncbi request reprint [Hospitalizations in a cohort of 175 severely drug-addicted patients of a medically managed opiate withdrawal project]
    M Hoffmann
    ,
    Praxis (Bern 1994) 90:2094-101. 2001
    ..However, as shown in earlier studies, the incidence of HIV drastically dropped. Hence, it may be that a longer follow-up may prove beneficial regarding the incidence of hospitalisations...
  20. ncbi request reprint Onset and pattern of substance use in intravenous drug users of an opiate maintenance program
    C Zinkernagel
    Outpatient Department of Internal Medicine, University Hospital Basel, Petersgraben 4, CH-4031 Basel, Switzerland
    Drug Alcohol Depend 64:105-9. 2001
    ..CONCLUSIONS: Specific knowledge about the age of onset and sequence of substances used by drug addicts may help to prevent substance use more age specifically...