C M Brown

Summary

Affiliation: University of Fribourg
Country: Switzerland

Publications

  1. ncbi request reprint Water-induced thermogenesis reconsidered: the effects of osmolality and water temperature on energy expenditure after drinking
    Clive M Brown
    Department of Medicine, Division of Physiology, University of Fribourg, Rue du Musee 5, 1700 Fribourg, Switzerland
    J Clin Endocrinol Metab 91:3598-602. 2006
  2. doi request reprint Sugary drinks in the pathogenesis of obesity and cardiovascular diseases
    C M Brown
    Division of Physiology, Department of Medicine, University of Fribourg, Fribourg, Switzerland
    Int J Obes (Lond) 32:S28-34. 2008
  3. ncbi request reprint Cardiovascular responses to water drinking: does osmolality play a role?
    Clive M Brown
    Dept of Medicine, Div of Physiology, Univ of Fribourg, Rue du Musee 5, 1700 Fribourg, Switzerland
    Am J Physiol Regul Integr Comp Physiol 289:R1687-92. 2005
  4. doi request reprint Fructose ingestion acutely elevates blood pressure in healthy young humans
    Clive M Brown
    Division of Physiology, Department of Medicine, University of Fribourg, Rue du Musee 5, 1700 Fribourg, Switzerland
    Am J Physiol Regul Integr Comp Physiol 294:R730-7. 2008
  5. doi request reprint A simple deep breathing test reveals altered cerebral autoregulation in type 2 diabetic patients
    C M Brown
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Diabetologia 51:756-61. 2008
  6. ncbi request reprint Effects of lower body negative pressure on cardiac and vascular responses to carotid baroreflex stimulation
    C M Brown
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Physiol Res 52:637-45. 2003
  7. ncbi request reprint Altered cerebral regulation in type 2 diabetic patients with cardiac autonomic neuropathy
    H Marthol
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany
    Diabetologia 49:2481-7. 2006
  8. ncbi request reprint Impairment of parasympathetic baroreflex responses in migraine patients
    E O Sanya
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Germany
    Acta Neurol Scand 111:102-7. 2005
  9. ncbi request reprint Impaired cardiovagal and vasomotor responses to baroreceptor stimulation in type II diabetes mellitus
    E O Sanya
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Eur J Clin Invest 33:582-8. 2003
  10. ncbi request reprint Enhanced external counterpulsation does not compromise cerebral autoregulation
    H Marthol
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Acta Neurol Scand 111:34-41. 2005

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Water-induced thermogenesis reconsidered: the effects of osmolality and water temperature on energy expenditure after drinking
    Clive M Brown
    Department of Medicine, Division of Physiology, University of Fribourg, Rue du Musee 5, 1700 Fribourg, Switzerland
    J Clin Endocrinol Metab 91:3598-602. 2006
    ..However, the concept of a thermogenic effect of water is controversial because other studies have found that water drinking does not increase energy expenditure...
  2. doi request reprint Sugary drinks in the pathogenesis of obesity and cardiovascular diseases
    C M Brown
    Division of Physiology, Department of Medicine, University of Fribourg, Fribourg, Switzerland
    Int J Obes (Lond) 32:S28-34. 2008
    ..This review focuses on the potential role of sugar drinks, particularly the fructose component, in the pathogenesis of obesity and cardiovascular diseases...
  3. ncbi request reprint Cardiovascular responses to water drinking: does osmolality play a role?
    Clive M Brown
    Dept of Medicine, Div of Physiology, Univ of Fribourg, Rue du Musee 5, 1700 Fribourg, Switzerland
    Am J Physiol Regul Integr Comp Physiol 289:R1687-92. 2005
    ..That these effects were absent after drinking physiological saline indicate that the cardiovascular responses to water drinking are influenced by its hypoosmotic properties...
  4. doi request reprint Fructose ingestion acutely elevates blood pressure in healthy young humans
    Clive M Brown
    Division of Physiology, Department of Medicine, University of Fribourg, Rue du Musee 5, 1700 Fribourg, Switzerland
    Am J Physiol Regul Integr Comp Physiol 294:R730-7. 2008
    ..In particular, fructose ingestion elicits an increase in blood pressure that is probably mediated by an increase in cardiac output without compensatory peripheral vasodilatation...
  5. doi request reprint A simple deep breathing test reveals altered cerebral autoregulation in type 2 diabetic patients
    C M Brown
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Diabetologia 51:756-61. 2008
    ..The purpose of this study was to evaluate the autoregulation of cerebral blood flow in diabetic patients using a simple method that could easily be applied to the clinical routine screening of diabetic patients...
  6. ncbi request reprint Effects of lower body negative pressure on cardiac and vascular responses to carotid baroreflex stimulation
    C M Brown
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Physiol Res 52:637-45. 2003
    ..Enhanced blood pressure responses to neck suction during higher levels of LBNP are not necessarily the result of a reflex interaction but may serve to protect the circulation from fluctuations in blood pressure while standing...
  7. ncbi request reprint Altered cerebral regulation in type 2 diabetic patients with cardiac autonomic neuropathy
    H Marthol
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany
    Diabetologia 49:2481-7. 2006
    ..We evaluated the technique of oscillatory neck suction at 0.1 Hz to quantify cerebral regulation in diabetic patients and healthy control subjects...
  8. ncbi request reprint Impairment of parasympathetic baroreflex responses in migraine patients
    E O Sanya
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Germany
    Acta Neurol Scand 111:102-7. 2005
    ..The aim of this study was to assess baroreflex regulation of the heart rate and blood vessels in migraine patients in comparison with healthy controls...
  9. ncbi request reprint Impaired cardiovagal and vasomotor responses to baroreceptor stimulation in type II diabetes mellitus
    E O Sanya
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Eur J Clin Invest 33:582-8. 2003
    ..However, the role of sympathetic mediated baroreflex vasomotor control of the blood vessels is not well defined. We therefore assessed the vasomotor responses to sinusoidal baroreceptor stimulation in diabetic patients...
  10. ncbi request reprint Enhanced external counterpulsation does not compromise cerebral autoregulation
    H Marthol
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Acta Neurol Scand 111:34-41. 2005
    ..In this study, we assessed EECP effects on dynamic cerebral autoregulation (CA)...
  11. ncbi request reprint Effects of age on the cardiac and vascular limbs of the arterial baroreflex
    C M Brown
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Eur J Clin Invest 33:10-6. 2003
    ..The aim of this study was to assess the effects of ageing on baroreflex control of the heart and blood vessels...
  12. pmc Transcranial Doppler sonography during head up tilt suggests preserved central sympathetic activation in familial dysautonomia
    M J Hilz
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    J Neurol Neurosurg Psychiatry 72:657-60. 2002
    ..Cerebral autoregulation was assessed by transcranial Doppler sonography in 10 patients with familial dysautonomia and 10 age matched controls...
  13. ncbi request reprint Delayed cerebrovascular autoregulatory response to ergometer exercise in normotensive elderly humans
    Josef G Heckmann
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Cerebrovasc Dis 16:423-9. 2003
    ..The aim of this study was to determine the effect of ergometer stress on cerebrovascular haemodynamics in elderly healthy individuals in comparison with young healthy individuals, using non-invasive methods...
  14. ncbi request reprint Impaired cardiovascular responses to baroreflex stimulation in open-angle and normal-pressure glaucoma
    Clive M Brown
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, Germany
    Clin Sci (Lond) 102:623-30. 2002
    ....
  15. ncbi request reprint Assessment of cerebrovascular and cardiovascular responses to lower body negative pressure as a test of cerebral autoregulation
    Clive M Brown
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, Germany
    J Neurol Sci 208:71-8. 2003
    ..Furthermore, assessment of cardiovascular and cerebrovascular parameters during LBNP may provide a useful clinical test of cerebral autoregulation...
  16. ncbi request reprint Effect of physical countermaneuvers on orthostatic hypotension in familial dysautonomia
    Marcin Tutaj
    Department of Neurology, Jagiellonian University, Botaniczna 3, 31503, Krakow, Poland
    J Neurol 253:65-72. 2006
    ..Suitability and effectiveness of a specific countermaneuver depends on the orthopedic or neurological complications of each FD patient and must be individually tested before a therapeutic recommendation can be given...
  17. ncbi request reprint Effect of cold face stimulation on cerebral blood flow in humans
    Clive M Brown
    Department of Neurology, Autonomic Laboratory, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Brain Res Bull 61:81-6. 2003
    ..However, responses of the cerebral blood flow have not yet been evaluated. We undertook this study to assess the effect of cold face stimulation on the cerebral circulation in humans...
  18. ncbi request reprint Abnormal heart rate and blood pressure responses to baroreflex stimulation in multiple sclerosis patients
    Emmanuel O Sanya
    Autonomic Laboratory, Dept of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Clin Auton Res 15:213-8. 2005
    ..27+/-0.29 ln ms(2)). These results indicate that in MS patients, baroreflex dysfunction is not only restricted to the cardiovagal limb of the baroreflex, but that the sympathetic modulation of the blood vessels is also affected...
  19. ncbi request reprint Dynamic cerebral autoregulation remains stable during physical challenge in healthy persons
    Miroslaw Brys
    Department of Neurology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Am J Physiol Heart Circ Physiol 285:H1048-54. 2003
    ..CA seems to compensate for the hemodynamic effects and increasing CO2 levels during exercise...
  20. ncbi request reprint Dynamic cerebral autoregulation is impaired in glaucoma
    Marcin Tutaj
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    J Neurol Sci 220:49-54. 2004
    ..Although there is evidence of vasomotor dysregulation with decreased peripheral and ocular blood flow, cerebral autoregulation (CA) has not yet been evaluated. The aim of our study was to assess dynamic CA in patients with NPG and POAG...
  21. ncbi request reprint Cerebral autoregulation is compromised during simulated fluctuations in gravitational stress
    Clive M Brown
    Autonomic Laboratory, Dept of Neurology, University of Erlangen Nuremberg, Germany
    Eur J Appl Physiol 91:279-86. 2004
    ..Furthermore, this effect seems to be more pronounced at higher frequencies of oscillatory stress...
  22. ncbi request reprint Increased hypoxic blood pressure response in patients with amyotrophic lateral sclerosis
    Martin J Hecht
    Department of Neurology, Friedrich Alexander University of Erlangen Nuremberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    J Neurol Sci 213:47-53. 2003
    ..This study was performed to assess cardiovascular and ventilatory responses to hypercapnic and hypoxic stimulation in ALS patients with impaired baroreflex function...
  23. ncbi request reprint Orthostatic challenge reveals impaired vascular resistance control, but normal venous pooling and capillary filtration in familial dysautonomia
    Clive M Brown
    Autonomic Laboratory, Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Clin Sci (Lond) 104:163-9. 2003
    ..This may be due, in part, to a preserved myogenic response to increased vascular pressure in the dependent vascular beds...
  24. ncbi request reprint Baroreflex stimulation shows impaired cardiovagal and preserved vasomotor function in early-stage amyotrophic lateral sclerosis
    Max J Hilz
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Amyotroph Lateral Scler Other Motor Neuron Disord 3:137-44. 2002
    ..This study was undertaken to assess baroreflex-mediated vagal and sympathetic cardiovascular control of the heart and blood vessels in ALS patients...