Christopher J Bockisch

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. doi request reprint Curing a 96-year-old patient afflicted with benign paroxysmal positional vertigo on a motorized turntable
    Christopher J Bockisch
    Department of Neurology, University Hospital Zurich Department of Ophthalmology, University Hospital Zurich Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich
    Clin Interv Aging 9:589-91. 2014
  2. doi request reprint Eye position dependency of nystagmus during constant vestibular stimulation
    Christopher J Bockisch
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    Exp Brain Res 226:175-82. 2013
  3. pmc Development of eye position dependency of slow phase velocity during caloric stimulation
    Christopher J Bockisch
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, Zurich, Switzerland
    PLoS ONE 7:e51409. 2012
  4. doi request reprint Alexander's law and the oculomotor neural integrator: three-dimensional eye velocity in patients with an acute vestibular asymmetry
    Christopher J Bockisch
    Department of Otorhinolaryngology, Head and Neck Surgery, Zurich University Hospital, Zurich, Switzerland
    J Neurophysiol 100:3105-16. 2008
  5. ncbi request reprint Vestibular contribution to the planning of reach trajectories
    Christopher J Bockisch
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, Zurich, Switzerland
    Exp Brain Res 182:387-97. 2007
  6. ncbi request reprint Enhanced smooth pursuit eye movements in patients with bilateral vestibular deficits
    Christopher J Bockisch
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, CH 8091 Zurich, Switzerland
    Neuroreport 15:2617-20. 2004
  7. ncbi request reprint Human 3-D aVOR with and without otolith stimulation
    Christopher J Bockisch
    Department of Neurology, University Hospital Zurich, Frauenklinikstr 26, 8091 Zurich, Switzerland
    Exp Brain Res 161:358-67. 2005
  8. doi request reprint Egocentric and allocentric alignment tasks are affected by otolith input
    Alexander A Tarnutzer
    Dept of Neurology, Univ Hospital Zurich, Zurich, Switzerland
    J Neurophysiol 107:3095-106. 2012
  9. doi request reprint Head roll dependent variability of subjective visual vertical and ocular counterroll
    Alexander A Tarnutzer
    Department of Neurology, Zurich University Hospital, Zurich, Switzerland
    Exp Brain Res 195:621-6. 2009
  10. pmc Gaze holding in healthy subjects
    Giovanni Bertolini
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    PLoS ONE 8:e61389. 2013

Collaborators

Detail Information

Publications29

  1. doi request reprint Curing a 96-year-old patient afflicted with benign paroxysmal positional vertigo on a motorized turntable
    Christopher J Bockisch
    Department of Neurology, University Hospital Zurich Department of Ophthalmology, University Hospital Zurich Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich
    Clin Interv Aging 9:589-91. 2014
    ....
  2. doi request reprint Eye position dependency of nystagmus during constant vestibular stimulation
    Christopher J Bockisch
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    Exp Brain Res 226:175-82. 2013
    ..Alexander's law also developed, on average, in 10 s. We conclude that Alexander's law is not simply a consequence of non-reciprocal vestibular stimulation...
  3. pmc Development of eye position dependency of slow phase velocity during caloric stimulation
    Christopher J Bockisch
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, Zurich, Switzerland
    PLoS ONE 7:e51409. 2012
    ..These results suggest that Alexander's law may not be a consequence of a true adaptive mechanism...
  4. doi request reprint Alexander's law and the oculomotor neural integrator: three-dimensional eye velocity in patients with an acute vestibular asymmetry
    Christopher J Bockisch
    Department of Otorhinolaryngology, Head and Neck Surgery, Zurich University Hospital, Zurich, Switzerland
    J Neurophysiol 100:3105-16. 2008
    ..These results show that the horizontal and vertical oculomotor neural integrators react to altered vestibular input by maintaining different integrating time constants depending on gaze direction...
  5. ncbi request reprint Vestibular contribution to the planning of reach trajectories
    Christopher J Bockisch
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, Zurich, Switzerland
    Exp Brain Res 182:387-97. 2007
    ..Since vestibular stimulation also alters the perceived location of targets, vestibular signals probably influence all stages of the sensorimotor pathway transforming the desired goal of a reach into specific motor-unit innervation...
  6. ncbi request reprint Enhanced smooth pursuit eye movements in patients with bilateral vestibular deficits
    Christopher J Bockisch
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, CH 8091 Zurich, Switzerland
    Neuroreport 15:2617-20. 2004
    ..We suggest that the challenge of living with a deficient vestibular system caused an enhancement in the pursuit system, which contributes to the patient's overall compensation...
  7. ncbi request reprint Human 3-D aVOR with and without otolith stimulation
    Christopher J Bockisch
    Department of Neurology, University Hospital Zurich, Frauenklinikstr 26, 8091 Zurich, Switzerland
    Exp Brain Res 161:358-67. 2005
    ..This could be because, in humans, typical yaw head movements will stimulate the otoliths to a much lesser extent then typical pitch and roll head movements...
  8. doi request reprint Egocentric and allocentric alignment tasks are affected by otolith input
    Alexander A Tarnutzer
    Dept of Neurology, Univ Hospital Zurich, Zurich, Switzerland
    J Neurophysiol 107:3095-106. 2012
    ..Such a shared mechanism for both paradigms and frames of reference is supported by the significantly correlated trial-to-trial variabilities...
  9. doi request reprint Head roll dependent variability of subjective visual vertical and ocular counterroll
    Alexander A Tarnutzer
    Department of Neurology, Zurich University Hospital, Zurich, Switzerland
    Exp Brain Res 195:621-6. 2009
    ..We propose that the similarities in variability reflect a common otolith input, which, however, is subject to distinct central processing for determining the gain of SVV and OCR...
  10. pmc Gaze holding in healthy subjects
    Giovanni Bertolini
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    PLoS ONE 8:e61389. 2013
    ..As a consequence, gaze-holding performance declines more rapidly at large eccentricities...
  11. pmc Hysteresis of haptic vertical and straight ahead in healthy human subjects
    Alexander A Tarnutzer
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, CH 8091 Zurich, Switzerland
    BMC Neurosci 13:114. 2012
    ..precision grip) and gender, and compared findings with perceived straight-ahead (PSA). Healthy subjects repetitively performed adjustments along SHV (n = 21) and PSA (n = 10) in complete darkness...
  12. pmc Precision and accuracy of the subjective haptic vertical in the roll plane
    Jeanine R Schuler
    Department of Neurology, Zurich University Hospital, Zurich, Switzerland
    BMC Neurosci 11:83. 2010
    ..Twelve healthy right-handed human subjects (handedness assessed based on subjects' verbal report) adjusted a rod with the right hand along perceived earth-vertical during static head roll-tilts (0-360 degrees , steps of 20 degrees )...
  13. ncbi request reprint Asymmetric short-term adaptation of the vertical vestibulo-ocular reflex in humans
    Sarah Marti
    Neurology Department, Zurich University Hospital, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    Exp Brain Res 172:343-50. 2006
    ..The unexpected asymmetric decrease of the VVOR gain after symmetric visual cancellation may be related to the directional preferences of vertical gaze-velocity sensitive Purkinje cells in the flocculus for the downward direction...
  14. doi request reprint A new dynamic visual acuity test to assess peripheral vestibular function
    Domenic Vital
    Department of Otorhinolaryngology Head and Neck Surgery, Zurich University Hospital, Frauenklinikstrasse 24, CH 8091 Zurich, Switzerland
    Arch Otolaryngol Head Neck Surg 136:686-91. 2010
    ....
  15. ncbi request reprint Eye movements during multi-axis whole-body rotations
    Christopher J Bockisch
    Department of Neurology, University Hospital Zurich, Switzerland
    J Neurophysiol 89:355-66. 2003
    ..Our study, supported by other experiments, also indicates that static otolith signals exhibit considerably smaller effects on eye movements in humans than in monkeys...
  16. doi request reprint Dynamic cyclovergence during vertical translation in humans
    Itsaso Olasagasti
    Department of Neurology, University Hospital Zurich, CH 8091 Zurich, Switzerland
    J Neurosci 31:9991-7. 2011
    ..Furthermore, we suggest that this cyclovergence response in humans is a vestige of the response of lateral-eyed animals to vertical linear acceleration of the head...
  17. doi request reprint Relative diagnostic value of ocular vestibular evoked potentials and the subjective visual vertical during tilt and eccentric rotation
    Yulia Valko
    Department of Neurology, University Hospital Zurich, Switzerland
    Clin Neurophysiol 122:398-404. 2011
    ....
  18. doi request reprint A re-examination of the time constant of the oculomotor neural integrator in human
    Elham Khojasteh
    Oculomotor Laboratory, University Hospital Zurich, CH 8091 Zurich, Switzerland
    Conf Proc IEEE Eng Med Biol Soc 2012:4780-3. 2012
    ..Nevertheless, a consistent trend did not emerge. Consequently, cross subject averaging eliminates idiosyncratic nonlinear patterns and the average can be approximated by a linear function inside the range that was tested...
  19. pmc Is vestibular self-motion perception controlled by the velocity storage? Insights from patients with chronic degeneration of the vestibulo-cerebellum
    Giovanni Bertolini
    Department of Neurology, Zurich University Hospital, Zurich, Switzerland
    PLoS ONE 7:e36763. 2012
    ..We therefore set out to explore both responses in patients with vestibulo-cerebellar degeneration...
  20. doi request reprint Positive or negative feedback of optokinetic signals: degree of the misrouted optic flow determines system dynamics of human ocular motor behavior
    Chien Cheng Chen
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    Invest Ophthalmol Vis Sci 55:2297-306. 2014
    ..Because the misrouting in human patients (e.g., with a condition of albinism or achiasmia) is partial, both positive- and negative-feedback loops co-exist. How this co-existence affects human ocular motor behavior remains unclear...
  21. doi request reprint Velocity storage mechanism in zebrafish larvae
    Chien Cheng Chen
    M Ying Yu Huang or D Straumann Neurology Department, University Hospital Zurich, Frauenklinikstrasse 26, CH 8091 Zurich, Switzerland or
    J Physiol 592:203-14. 2014
    ..Our results suggest that the VSM develops prior to and without the need for a functional aVOR. It may be critical to ocular motor control in early development as it increases the efficiency of the OKR...
  22. pmc Modulation of internal estimates of gravity during and after prolonged roll-tilts
    Alexander A Tarnutzer
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    PLoS ONE 8:e78079. 2013
    ..We therefore favor central adaptation, most likely a shift in prior knowledge towards the previous roll orientation, to explain the post-tilt bias...
  23. pmc Differential effects of visual feedback on subjective visual vertical accuracy and precision
    Daniel Bjasch
    Department of Neurology, Zurich University Hospital, Zurich, Switzerland
    PLoS ONE 7:e49311. 2012
    ..The mechanisms behind the SVV therefore, remained stable, which is also supported by the fact that SVV precision - depending mostly on otolith input - was not affected by visual feedback...
  24. doi request reprint A mechanism for eye position effects on spontaneous nystagmus
    Elham Khojasteh
    Department of Otorhinolaryngology, Head and Neck Surgery, Vestibulo Oculomotor Laboratory, University Hospital Zurich, Zurich, Switzerland
    Conf Proc IEEE Eng Med Biol Soc 2012:3572-5. 2012
    ..The proposed transformations in population response functions could happen immediately following a lesion and can be useful to stabilize gaze in part of the gaze field...
  25. doi request reprint A dynamic model for eye-position-dependence of spontaneous nystagmus in acute unilateral vestibular deficit (Alexander's Law)
    Elham Khojasteh
    Department of Otorhinolaryngology, University Hospital Zurich, CH 8091, Zurich, Switzerland
    Eur J Neurosci 37:141-9. 2013
    ..The proposed model demonstrates possible consequences of acute peripheral deficits for the function of the velocity-to-position neural integrator of the ocular motor system and the vestibulo-ocular reflex...
  26. ncbi request reprint Prolonged asymmetric smooth-pursuit stimulation leads to downbeat nystagmus in healthy human subjects
    Sarah Marti
    Neurology Department, Zurich University Hospital, Zurich, Switzerland
    Invest Ophthalmol Vis Sci 46:143-9. 2005
    ..The purpose of this study was to elaborate a possible link between an imbalance in the vertical smooth-pursuit system and DBN by relying on a healthy human model...
  27. doi request reprint Neurophysiology: vertigo in MRI machines
    Dominik Straumann
    Department of Neurology, University Hospital Zurich, Switzerland
    Curr Biol 21:R806-7. 2011
    ..Subjects of brain-imaging studies often report experiencing vertigo while in MRI machines; a new study shows that the magnetic field stimulates the vestibular sensors in the inner ear by a Lorentz force...
  28. doi request reprint Modulation of saccade curvature by ocular counterroll
    Konrad P Weber
    Department of Neurology, Zurich University Hospital, Zurich, Switzerland
    Invest Ophthalmol Vis Sci 50:1158-67. 2009
    ..The authors asked whether saccade curvatures are systematically influenced by static ocular counterroll (OCR)...
  29. ncbi request reprint Dependence of adaptation of the human vertical angular vestibulo-ocular reflex on gravity
    Sergei B Yakushin
    Department of Neurology, Mount Sinai School of Medicine, 1 East 100th Street, Box 1135, New York, NY 10029, USA
    Exp Brain Res 152:137-42. 2003
    ..We conclude that there is a component of the vertical aVOR gain change in humans that is dependent on the head orientation in which the gain was adapted, and that this dependence can persist for substantial periods...