Johannes Blum

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. pmc Cardiac alterations in human African trypanosomiasis (T.b. gambiense) with respect to the disease stage and antiparasitic treatment
    Johannes A Blum
    Swiss Tropical Institute, Basel, Switzerland
    PLoS Negl Trop Dis 3:e383. 2009
  2. doi request reprint [Skin diseases in travellers returning from tropical countries]
    Johannes Blum
    Swiss Tropical and Public Health Institute, Basel
    Ther Umsch 70:335-42. 2013
  3. doi request reprint Human African trypanosomiasis in endemic populations and travellers
    J A Blum
    Medical Department, Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002, Basel, Switzerland
    Eur J Clin Microbiol Infect Dis 31:905-13. 2012
  4. doi request reprint Cardiac involvement in African and American trypanosomiasis
    Johannes A Blum
    Swiss Tropical Institute, Basel, Switzerland
    Lancet Infect Dis 8:631-41. 2008
  5. ncbi request reprint Sleeping hearts: the role of the heart in sleeping sickness (human African trypanosomiasis)
    Johannes A Blum
    Swiss Tropical Institute, Basel, Switzerland
    Trop Med Int Health 12:1422-32. 2007
  6. ncbi request reprint Sleeping glands? - The role of endocrine disorders in sleeping sickness (T.b. gambiense Human African Trypanosomiasis)
    Johannes A Blum
    Swiss Tropical Institute, Socinstrasse 57, CH 4002 Basel, Switzerland
    Acta Trop 104:16-24. 2007
  7. ncbi request reprint [The worm in the brain]
    J Blum
    Schweizerisches Tropeninstitut, Basel
    Ther Umsch 62:779-86. 2005
  8. ncbi request reprint Clinical aspects of 2541 patients with second stage human African trypanosomiasis
    Johannes Blum
    Swiss Tropical Institute, Medical and Diagnostic Services, Socinstrasse 57, 4002 Basel, Switzerland
    Acta Trop 97:55-64. 2006
  9. ncbi request reprint Clinical and serologic responses to human 'apathogenic' trypanosomes
    J Blum
    Swiss Tropical Institute, Department of Medical and Diagnostic Services, Basel
    Trans R Soc Trop Med Hyg 99:795-7. 2005
  10. ncbi request reprint Treatment of cutaneous leishmaniasis among travellers
    J Blum
    Swiss Tropical Institute, Socinstrasse 57, 4002 Basel, Switzerland
    J Antimicrob Chemother 53:158-66. 2004

Collaborators

Detail Information

Publications31

  1. pmc Cardiac alterations in human African trypanosomiasis (T.b. gambiense) with respect to the disease stage and antiparasitic treatment
    Johannes A Blum
    Swiss Tropical Institute, Basel, Switzerland
    PLoS Negl Trop Dis 3:e383. 2009
    ....
  2. doi request reprint [Skin diseases in travellers returning from tropical countries]
    Johannes Blum
    Swiss Tropical and Public Health Institute, Basel
    Ther Umsch 70:335-42. 2013
    ....
  3. doi request reprint Human African trypanosomiasis in endemic populations and travellers
    J A Blum
    Medical Department, Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002, Basel, Switzerland
    Eur J Clin Microbiol Infect Dis 31:905-13. 2012
    ..However, new molecular diagnostic technologies are under development. A promising new drug combination is currently evaluated in a phase 3 b study and further new drugs are under evaluation...
  4. doi request reprint Cardiac involvement in African and American trypanosomiasis
    Johannes A Blum
    Swiss Tropical Institute, Basel, Switzerland
    Lancet Infect Dis 8:631-41. 2008
    ..HAT cardiopathy in general is benign and does not cause relevant congestive heart failure and subsides with treatment. We review the differences between the American and African trypanosomiasis with the main focus on the heart...
  5. ncbi request reprint Sleeping hearts: the role of the heart in sleeping sickness (human African trypanosomiasis)
    Johannes A Blum
    Swiss Tropical Institute, Basel, Switzerland
    Trop Med Int Health 12:1422-32. 2007
    ....
  6. ncbi request reprint Sleeping glands? - The role of endocrine disorders in sleeping sickness (T.b. gambiense Human African Trypanosomiasis)
    Johannes A Blum
    Swiss Tropical Institute, Socinstrasse 57, CH 4002 Basel, Switzerland
    Acta Trop 104:16-24. 2007
    ..However, a transitory adrenal insufficiency was suspected in 8% of HAT patients at admission and in 9% at discharge. All values were normal at follow-up 3 months later...
  7. ncbi request reprint [The worm in the brain]
    J Blum
    Schweizerisches Tropeninstitut, Basel
    Ther Umsch 62:779-86. 2005
    ..Anthelminthic treatment may induce a host reaction with inflammation and deterioration of the clinical picture and has to be performed cautiously and under protection with corticosteroids...
  8. ncbi request reprint Clinical aspects of 2541 patients with second stage human African trypanosomiasis
    Johannes Blum
    Swiss Tropical Institute, Medical and Diagnostic Services, Socinstrasse 57, 4002 Basel, Switzerland
    Acta Trop 97:55-64. 2006
    ..4-61.2%). Fever is most frequently reported in children between 2 and 14 years of age (26.1-28.7%) and malnutrition is significantly more frequently observed in children of all ages (43-56%) than in adults (23.5%)...
  9. ncbi request reprint Clinical and serologic responses to human 'apathogenic' trypanosomes
    J Blum
    Swiss Tropical Institute, Department of Medical and Diagnostic Services, Basel
    Trans R Soc Trop Med Hyg 99:795-7. 2005
    ..We performed serologic tests because the patient was worried about HAT after receiving tsetse bites. The possibilities of an infection with human 'apathogenic' trypanosomes such as T. b. brucei, T. congolense or T. vivax are discussed...
  10. ncbi request reprint Treatment of cutaneous leishmaniasis among travellers
    J Blum
    Swiss Tropical Institute, Socinstrasse 57, 4002 Basel, Switzerland
    J Antimicrob Chemother 53:158-66. 2004
    ..An overview of published treatment options and a treatment recommendation is given for each of the most important species. The level of evidence of the studies leading to these recommendations is given...
  11. ncbi request reprint Treatment of late stage sleeping sickness caused by T.b. gambiense: a new approach to the use of an old drug
    J Blum
    Swiss Tropical Institute, Basel, Switzerland
    Swiss Med Wkly 132:51-6. 2002
    ..Statistical analysis yielded no significant differences for adverse events between the two treatment protocols. The new schedule reduces the amount and cost for the drug by about one third, and those for hospitalisation by about half...
  12. pmc Safety and efficacy of the 10-day melarsoprol schedule for the treatment of second stage Rhodesiense sleeping sickness
    Irene Kuepfer
    Swiss Tropical and Public Heath Institute, Basel, Switzerland
    PLoS Negl Trop Dis 6:e1695. 2012
    ..Assessment of the safety and efficacy of a 10-day melarsoprol schedule in second stage T.b. rhodesiense patients and the effect of suramin-pretreatment on the incidence of encephalopathic syndrome (ES) during melarsoprol therapy...
  13. doi request reprint Human African trypanosomiasis
    Reto Brun
    Swiss Tropical Institute, Basel, Switzerland
    Lancet 375:148-59. 2010
    ..WHO has stated that if national control programmes, international organisations, research institutes, and philanthropic partners engage in concerted action, elimination of this disease might even be possible...
  14. pmc Spinal cystic echinococcosis--a systematic analysis and review of the literature: part 1. Epidemiology and anatomy
    Andreas Neumayr
    Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 7:e2450. 2013
    ..To fill this gap, we systematically reviewed the published literature of the last five decades to summarize and analyze the currently existing data on epidemiological and anatomical aspects of spinal CE. ..
  15. doi request reprint Risk perception of travelers to tropical and subtropical countries visiting a swiss travel health center
    Rosalie Zimmermann
    Departments of Medicine and Diagnostics, Swiss Tropical and Public Health Institute, Basel, Switzerland
    J Travel Med 20:3-10. 2013
    ..While most surveys on travel health knowledge, attitudes, and practices focus on malaria and vaccine-preventable diseases, noninfectious travel risks were included in this study...
  16. pmc In-hospital safety in field conditions of nifurtimox eflornithine combination therapy (NECT) for T. b. gambiense sleeping sickness
    Caecilia Schmid
    Department of Medicines Research, Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 6:e1920. 2012
    ..Documentation of its safety profile in field conditions will support its wider use...
  17. ncbi request reprint Efficacy of new, concise schedule for melarsoprol in treatment of sleeping sickness caused by Trypanosoma brucei gambiense: a randomised trial
    C Burri
    Swiss Tropical Institute, Basel
    Lancet 355:1419-25. 2000
    ..Despite these problems, melarsoprol is likely to remain the drug of choice for the next decade. We therefore did a randomised trial comparing the standard treatment schedule with a new, concise regimen...
  18. ncbi request reprint Clinical description of encephalopathic syndromes and risk factors for their occurrence and outcome during melarsoprol treatment of human African trypanosomiasis
    J Blum
    Swiss Tropical Institute, Basel, Switzerland
    Trop Med Int Health 6:390-400. 2001
    ..5), headache (RR 2.5), bullous eruptions (RR 4.5) and systolic hypotension (RR 2.6) were associated with an increased risk for the occurrence of encephalopathic syndromes especially of the coma type...
  19. doi request reprint Human African trypanosomiasis
    Reto Brun
    Department Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Socinstrasse 57, CH 4002 Basel, Switzerland
    Infect Dis Clin North Am 26:261-73. 2012
    ..Elimination of the disease is considered feasible provided better tools for diagnosis and treatment can be made available...
  20. pmc Sleeping sickness in travelers - do they really sleep?
    Karin Urech
    Swiss Tropical and Public Heath Institute, Basel, Switzerland
    PLoS Negl Trop Dis 5:e1358. 2011
    ..The diagnosis of HAT in Africans living outside the endemic region is often missed or delayed, leading to presentation with advanced stages of the disease...
  21. pmc Spinal cystic echinococcosis--a systematic analysis and review of the literature: part 2. Treatment, follow-up and outcome
    Andreas Neumayr
    Swiss Tropical and Public Health Institute, Basel, Switzerland
    PLoS Negl Trop Dis 7:e2458. 2013
    ..We systematically reviewed the published literature of the last five decades to update and summarize the currently existing data on treatment, follow-up and outcome of spinal CE. ..
  22. doi request reprint Treatment of mucosal leishmaniasis (L. infantum) with miltefosine in a patient with Good syndrome
    Marcel Stoeckle
    Swiss Tropical and Public Health Institute, Basel, Switzerland Clinic of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
    Acta Trop 128:168-70. 2013
    ..Miltefosine is an option for treating Old World leishmaniasis (Leishmania infantum) and immunodeficiency should be considered in patients with recurrent leishmaniasis. ..
  23. doi request reprint Not to be missed! Differential diagnoses of common dermatological problems in returning travellers
    Andreas Neumayr
    Swiss Tropical and Public Health Institute, Socinstrasse 57, 4051 Basel, Switzerland University of Basel, Basel, Switzerland
    Travel Med Infect Dis 11:337-49. 2013
    ..This article provides an overview of the most common and the 'not to be missed' dermatological diagnoses in international travellers. ..
  24. doi request reprint Neglected tropical diseases: diagnosis, clinical management, treatment and control
    Jurg Utzinger
    Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel and University of Basel, Switzerland
    Swiss Med Wkly 142:w13727. 2012
    ....
  25. doi request reprint The difficulty in diagnosis and treatment of leprosy
    Carmen Forno
    Department of Dermatology, University Hospital, Basel, Switzerland
    J Travel Med 17:281-3. 2010
    ..Leprosy is still an important and debilitating disease with a broad clinical spectrum. However, this disease occurs most often endemically, and as an imported disease it can also still be recognized in the nonendemic industrialized world...
  26. doi request reprint Local or systemic treatment for New World cutaneous leishmaniasis? Re-evaluating the evidence for the risk of mucosal leishmaniasis
    Johannes Blum
    Swiss Tropical and Public Health Institute, Socinstrasse 57, 4002 Basel, Switzerland
    Int Health 4:153-63. 2012
    ....
  27. ncbi request reprint [Malaria--chemoprophylaxis 2001]
    F R Hatz
    Departementsleiter Medizin and Diagnostik, Schweizerisches Tropeninstitut, Postfach, CH 4002 Basel
    Ther Umsch 58:347-51. 2001
    ..Mefloquine, doxycycline, chloroquine plus proguanil, and presumably soon also atovaquone plus proguanil are available in Switzerland for chemoprophylaxis...
  28. ncbi request reprint [Parasites as a cause of urticaria. Helminths and protozoa as triggers of hives?]
    U Ronellenfitsch
    Abteilung für Medizin und Diagnostik, Schweizerisches Tropeninstitut, Socinstrasse 57, 4002 Basel
    Hautarzt 58:133-4, 136-41. 2007
    ..This review presents the most important parasitic causes of urticaria and provides relevant details regarding personal history, clinical presentation, diagnosis and therapy...
  29. ncbi request reprint New world cutaneous leishmaniasis in travellers
    Eli Schwartz
    The Center for Geographic Medicine and Tropical Diseases, Chaim Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Israel
    Lancet Infect Dis 6:342-9. 2006
    ..Although only used in a small number of patients thus far, liposomal amphotericin B shows promising results. Further studies are needed to find efficacious and better-tolerated drugs for new world leishmaniasis...
  30. ncbi request reprint Nonoperative treatment of splenic rupture in malaria tropica: review of literature and case report
    Christian T Hamel
    Department of Surgery, University Hospital of Basel, General Surgical Service, Spitalstrasse 21, 4031, Basel, Switzerland
    Acta Trop 82:1-5. 2002
    ..The ability to properly diagnose and manage these complications is important. Spleen-conserving procedures should be the standard whenever possible especially in patients with a high likelihood of future exposure to malaria...
  31. ncbi request reprint Chest pain after travel to the tropics
    Luigia Elzi
    Division of Infectious Diseases University Hospital Basel CH 4002 Basel, Switzerland
    Lancet 363:1198. 2004