Heike A Bischoff-Ferrari

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. doi request reprint Vitamin D and fracture prevention
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich, Zurich, Switzerland
    Endocrinol Metab Clin North Am 39:347-53, table of contents. 2010
  2. doi request reprint Vitamin D - from essentiality to functionality
    Heike Bischoff-Ferrari
    University Hospital, Zurich, Switzerland
    Int J Vitam Nutr Res 82:321-6. 2012
  3. ncbi request reprint Relevance of vitamin D in bone and muscle health of cancer patients
    Heike Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich and City Hospital Waid, Dept of Rheumatology, University Hospital Zurich, Gloriastrasse 25, 8091 Zurich, Switzerland
    Anticancer Agents Med Chem 13:58-64. 2013
  4. doi request reprint Which vitamin D oral supplement is best for postmenopausal women?
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University Hospital Zurich, Switzerland
    Curr Osteoporos Rep 10:251-7. 2012
  5. ncbi request reprint Vitamin D and fracture prevention
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich, Zurich, Switzerland
    Rheum Dis Clin North Am 38:107-13. 2012
  6. doi request reprint Relevance of vitamin D in muscle health
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich and City Hospital Waid, Gloriastrasse 25, 8091, Zurich, Switzerland
    Rev Endocr Metab Disord 13:71-7. 2012
  7. ncbi request reprint How to select the doses of vitamin D in the management of osteoporosis
    H A Bischoff-Ferrari
    Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091, Zurich, Switzerland
    Osteoporos Int 18:401-7. 2007
  8. doi request reprint Severe vitamin D deficiency in Swiss hip fracture patients
    H A Bischoff-Ferrari
    Department of Rheumatology, University Hospital, Zurich, Switzerland
    Bone 42:597-602. 2008
  9. doi request reprint Optimal serum 25-hydroxyvitamin D levels for multiple health outcomes
    Heike A Bischoff-Ferrari
    Deptartment of Rheumatology, Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland
    Adv Exp Med Biol 624:55-71. 2008
  10. doi request reprint Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich, University Hospital, Switzerland
    Arch Intern Med 169:551-61. 2009

Collaborators

Detail Information

Publications48

  1. doi request reprint Vitamin D and fracture prevention
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich, Zurich, Switzerland
    Endocrinol Metab Clin North Am 39:347-53, table of contents. 2010
    ..This article discusses the amount of vitamin D supplementation needed and the desirable 25-hydroxyvitamin D level to be achieved for optimal fracture prevention...
  2. doi request reprint Vitamin D - from essentiality to functionality
    Heike Bischoff-Ferrari
    University Hospital, Zurich, Switzerland
    Int J Vitam Nutr Res 82:321-6. 2012
    ..Notably, a higher 25-hydroxyvitamin D threshold of more than 60 nmol/l is needed for optimal functionality, fall and fracture in adults age 65 and older. ..
  3. ncbi request reprint Relevance of vitamin D in bone and muscle health of cancer patients
    Heike Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich and City Hospital Waid, Dept of Rheumatology, University Hospital Zurich, Gloriastrasse 25, 8091 Zurich, Switzerland
    Anticancer Agents Med Chem 13:58-64. 2013
    ..Finally, trial and epidemiological data will be reviewed to assess desirable serum 25-hydroxyvitamin D levels for optimal muscle health...
  4. doi request reprint Which vitamin D oral supplement is best for postmenopausal women?
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University Hospital Zurich, Switzerland
    Curr Osteoporos Rep 10:251-7. 2012
    ....
  5. ncbi request reprint Vitamin D and fracture prevention
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich, Zurich, Switzerland
    Rheum Dis Clin North Am 38:107-13. 2012
    ....
  6. doi request reprint Relevance of vitamin D in muscle health
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich and City Hospital Waid, Gloriastrasse 25, 8091, Zurich, Switzerland
    Rev Endocr Metab Disord 13:71-7. 2012
    ..Finally, trial and epidemiological data will be reviewed to assess desirable serum 25-hydroxyvitamin D levels for optimal muscle health...
  7. ncbi request reprint How to select the doses of vitamin D in the management of osteoporosis
    H A Bischoff-Ferrari
    Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091, Zurich, Switzerland
    Osteoporos Int 18:401-7. 2007
    ..Two main factors discussed in this review may help public health efforts to ensure desirable vitamin D levels for fall and fracture prevention, including (1) a sufficient dose of vitamin D and (2) improved adherence to supplementation...
  8. doi request reprint Severe vitamin D deficiency in Swiss hip fracture patients
    H A Bischoff-Ferrari
    Department of Rheumatology, University Hospital, Zurich, Switzerland
    Bone 42:597-602. 2008
    ..Most clinical guidelines for the prevention of hip fractures recommend 800 IU vitamin D per day. This dose shifted serum 25-hydroxyvitamin D levels (25(OH)D) in previous studies to between 60 and 100 nmol/l...
  9. doi request reprint Optimal serum 25-hydroxyvitamin D levels for multiple health outcomes
    Heike A Bischoff-Ferrari
    Deptartment of Rheumatology, Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland
    Adv Exp Med Biol 624:55-71. 2008
    ..While estimates suggest that 2000 IU vitamin D3 per day may successfully and safely achieve this goal, the implications of 2000 IU or higher doses for the total adult population need to be addressed in future studies...
  10. doi request reprint Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich, University Hospital, Switzerland
    Arch Intern Med 169:551-61. 2009
    ..Antifracture efficacy with supplemental vitamin D has been questioned by recent trials...
  11. doi request reprint Importance of vitamin D and calcium at older age
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University Hospital Zurich, Zurich, Switzerland
    Int J Vitam Nutr Res 78:286-92. 2008
    ..In combination with a vitamin D supplement, dairy products may be an optimal source of calcium at higher age as milk provides both calcium and protein...
  12. pmc Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials
    H A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich, Switzerland
    BMJ 339:b3692. 2009
    ..To test the efficacy of supplemental vitamin D and active forms of vitamin D with or without calcium in preventing falls among older individuals...
  13. doi request reprint Vitamin D: what is an adequate vitamin D level and how much supplementation is necessary?
    Heike Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich, Department of Rheumatology and Institute of Physical Medicine, Zurich, Switzerland
    Best Pract Res Clin Rheumatol 23:789-95. 2009
    ..Ideally, the target range for 25-hydroxyvitamin D should be at least 75 nmol l(-1), which may need more than 700-1000 IU vitamin D in individuals with severe vitamin D deficiency or those overweight...
  14. pmc Benefit-risk assessment of vitamin D supplementation
    H A Bischoff-Ferrari
    Centre on Aging and Mobility, Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091, Zurich, Switzerland
    Osteoporos Int 21:1121-32. 2010
    ..Current intake recommendations of 200 to 600 IU vitamin D per day may be insufficient for important disease outcomes reduced by vitamin D...
  15. doi request reprint Health effects of vitamin D
    Heike Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich and Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Switzerland
    Dermatol Ther 23:23-30. 2010
    ....
  16. doi request reprint Effect of high-dosage cholecalciferol and extended physiotherapy on complications after hip fracture: a randomized controlled trial
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich, University Hospital Zurich, Gloriastrasse 25, 8091 Zurich, Switzerland
    Arch Intern Med 170:813-20. 2010
    ..Care of elderly patients after hip fracture is not well established...
  17. ncbi request reprint Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trials
    Heike A Bischoff-Ferrari
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 86:1780-90. 2007
    ..The role of total calcium intake in the prevention of hip fracture risk has not been well established...
  18. doi request reprint Milk intake and risk of hip fracture in men and women: a meta-analysis of prospective cohort studies
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich, Zurich, Switzerland
    J Bone Miner Res 26:833-9. 2011
    ..91 (95% CI 0.81-1.01). Our conclusion is that in our meta-analysis of cohort studies, there was no overall association between milk intake and hip fracture risk in women but that more data are needed in men...
  19. ncbi request reprint Positive association between serum 25-hydroxyvitamin D level and bone density in osteoarthritis
    Heike A Bischoff-Ferrari
    Clinical Epidemiology Unit, Boston University, Boston, Massachusetts, USA
    Arthritis Rheum 53:821-6. 2005
    ..To describe the association between serum 25-hydroxyvitamin D (25[OH]D) level and bone mineral density (BMD) in persons with primary knee osteoarthritis (OA)...
  20. ncbi request reprint Effect of cholecalciferol plus calcium on falling in ambulatory older men and women: a 3-year randomized controlled trial
    Heike A Bischoff-Ferrari
    Department of Rheumatology and Institute for Physical Medicine, University Hospital Zurich, Zurich, Switzerland
    Arch Intern Med 166:424-30. 2006
    ..However, little is known about whether supplemental cholecalciferol plus calcium citrate malate will lower the long-term risk of falling in men, active older individuals, and older individuals with higher 25-hydroxyvitamin D levels...
  21. ncbi request reprint Is fall prevention by vitamin D mediated by a change in postural or dynamic balance?
    H A Bischoff-Ferrari
    Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091, Zurich, Switzerland
    Osteoporos Int 17:656-63. 2006
    ....
  22. ncbi request reprint Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes
    Heike A Bischoff-Ferrari
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 84:18-28. 2006
    ..The implications of higher doses for the entire adult population should be addressed in future studies...
  23. pmc Dietary calcium and serum 25-hydroxyvitamin D status in relation to BMD among U.S. adults
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich, Zurich, Switzerland
    J Bone Miner Res 24:935-42. 2009
    ..0001; men = 0.0001). Among men and women, 25(OH)D status seems to be the dominant predictor of BMD relative to calcium intake. Only women with 25(OH)D concentrations <50 nM seem to benefit from a higher calcium intake...
  24. ncbi request reprint Milk consumption during teenage years and risk of hip fractures in older adults
    Diane Feskanich
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Harvard University, Boston, Massachusetts
    JAMA Pediatr 168:54-60. 2014
    ..However, its role in hip fracture prevention is not established and high consumption may adversely influence risk by increasing height...
  25. ncbi request reprint Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials
    Heike A Bischoff-Ferrari
    Department of Nutrition, Harvard School of Public Health, Boston, Mass 02115, USA
    JAMA 293:2257-64. 2005
    ..The role and dose of oral vitamin D supplementation in nonvertebral fracture prevention have not been well established...
  26. ncbi request reprint Vitamin D intake and risk of incident hypertension: results from three large prospective cohort studies
    John P Forman
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Hypertension 46:676-82. 2005
    ..We conclude that higher intake of vitamin D is not associated with a lower risk of incident hypertension...
  27. ncbi request reprint Association between serum concentrations of 25-hydroxyvitamin D and gingival inflammation
    Thomas Dietrich
    Department of Health Policy and Health Services Research, Boston University Goldman School of Dental Medicine, Boston, MA 02118, USA
    Am J Clin Nutr 82:575-80. 2005
    ..Vitamin D has been shown to have immunomodulatory effects in in vitro and in animal studies. However, data from clinical studies of inflammatory diseases are scarce...
  28. ncbi request reprint Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged > or =60 y
    Heike A Bischoff-Ferrari
    Division of Aging, The Robert B Brigham Arthritis and Musculoskeletal Diseases Clinical Research Center, Brigham and Women s Hospital, 1620 Tremont Street, Boston, MA 02120, USA
    Am J Clin Nutr 80:752-8. 2004
    ..Vitamin D may improve muscle strength through a highly specific nuclear receptor in muscle tissue...
  29. doi request reprint A pooled analysis of vitamin D dose requirements for fracture prevention
    Heike A Bischoff-Ferrari
    Center on Aging and Mobility, University of Zurich and Waid City Hospital, Zurich, Switzerland
    N Engl J Med 367:40-9. 2012
    ..The results of meta-analyses examining the relationship between vitamin D supplementation and fracture reduction have been inconsistent...
  30. ncbi request reprint Effect of Vitamin D on falls: a meta-analysis
    Heike A Bischoff-Ferrari
    Division of Aging, Department of Medicine, Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02120, USA
    JAMA 291:1999-2006. 2004
    ..Falls among elderly individuals occur frequently, increase with age, and lead to substantial morbidity and mortality. The role of vitamin D in preventing falls among elderly people has not been well established...
  31. ncbi request reprint A higher dose of vitamin d reduces the risk of falls in nursing home residents: a randomized, multiple-dose study
    Kerry E Broe
    Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts 02131, USA
    J Am Geriatr Soc 55:234-9. 2007
    ..To determine the effect of four vitamin D supplement doses on falls risk in elderly nursing home residents...
  32. doi request reprint Therapy of osteoporosis with calcium and vitamin D
    Bess Dawson-Hughes
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA
    J Bone Miner Res 22:V59-63. 2007
    ....
  33. ncbi request reprint Need for additional calcium to reduce the risk of hip fracture with vitamin d supplementation: evidence from a comparative metaanalysis of randomized controlled trials
    Steven Boonen
    Leuven University Center for Metabolic Bone Diseases, Katholieke Universiteit Leuven, Belgium, and Brigham and Women s Hospital, Boston, MA 02115, USA
    J Clin Endocrinol Metab 92:1415-23. 2007
    ..which found that 700-800 IU/d vitamin D reduced hip fracture risk in elderly individuals by 25%, by defining the need for additional calcium supplementation in individuals receiving vitamin D for the prevention of hip fractures...
  34. ncbi request reprint Plasma 25-hydroxyvitamin D levels and risk of incident hypertension
    John P Forman
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Hypertension 49:1063-9. 2007
    ..31 (95% CI: 2.03 to 2.63) in men and 1.57 (95% CI: 1.44 to 1.72) in women. Plasma 25(OH)D levels are inversely associated with risk of incident hypertension...
  35. doi request reprint Vitamin D: role in pregnancy and early childhood
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich and City Hospital Waid, University Hospital, Switzerland
    Ann Nutr Metab 59:17-21. 2011
    ..This review will summarize the scientific basis that led to the most recent recommendations...
  36. doi request reprint High prevalence of severe vitamin D deficiency in combined antiretroviral therapy-naive and successfully treated Swiss HIV patients
    Nicolas J Mueller
    Division of Infectious Diseases and Hospital Epidemiology, Department of Medicine, University Hospital of Zurich, Zurich, Switzerland
    AIDS 24:1127-34. 2010
    ..To evaluate the prevalence of 25-hydroxyvitamin D [25(OH)D] deficiency in HIV-positive patients, a population at risk for osteoporosis...
  37. doi request reprint High-dose oral vitamin D3 supplementation in rheumatology patients with severe vitamin D3 deficiency
    Cord von Restorff
    Triemli Hospital, Zurich, Switzerland
    Bone 45:747-9. 2009
    ..The aim of this report is to describe changes of 25-hydroxyvitamin D (25(OH)D) serum concentrations achieved with a single oral dose of 300000 IU vitamin D3...
  38. pmc Effect of calcium supplementation on fracture risk: a double-blind randomized controlled trial
    Heike A Bischoff-Ferrari
    Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland
    Am J Clin Nutr 87:1945-51. 2008
    ..The effect of supplementation with calcium alone on risk fractures in a healthy population is not clear...
  39. ncbi request reprint Positive association between 25-hydroxy vitamin D levels and bone mineral density: a population-based study of younger and older adults
    Heike A Bischoff-Ferrari
    Division of Ageing, The Robert B Brigham Arthritis and Musculoskeletal Diseases Clinical Research Center, Boston, Massachusetts, USA
    Am J Med 116:634-9. 2004
  40. doi request reprint The role of falls in fracture prediction
    Heike A Bischoff-Ferrari
    Centre on Aging and Mobility, University of Zurich, Zurich, Switzerland
    Curr Osteoporos Rep 9:116-21. 2011
    ..Finally, fall prevention strategies and how these translate into fracture reduction are evaluated based on data from randomized controlled trials...
  41. doi request reprint Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline
    Michael F Holick
    Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Clin Endocrinol Metab 96:1911-30. 2011
    ..The objective was to provide guidelines to clinicians for the evaluation, treatment, and prevention of vitamin D deficiency with an emphasis on the care of patients who are at risk for deficiency...
  42. ncbi request reprint The 25-hydroxyvitamin D threshold for better health
    Heike A Bischoff-Ferrari
    Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Gloriastrasse 25, 8091 Zurich, Switzerland
    J Steroid Biochem Mol Biol 103:614-9. 2007
    ....
  43. pmc Effect of pre-operative neuromuscular training on functional outcome after total knee replacement: a randomized-controlled trial
    Erika O Huber
    Centre on Aging an Mobility, University Hospital Zurich and Waid City Hospital Zurich, University of Zurich, Gloriastrasse 25, Zurich 8091, Switzerland
    BMC Musculoskelet Disord 14:157. 2013
    ..Thus, improving functional status prior to surgery through exercise may improve after surgery outcome. However, results from several previous trials testing the concept have been inconclusive after surgery...
  44. pmc Multi-step immunofluorescent analysis of vitamin D receptor loci and myosin heavy chain isoforms in human skeletal muscle
    Lisa Ceglia
    Tufts Medical Center, Boston, MA, USA
    J Mol Histol 41:137-42. 2010
    ..This method can thus be a useful approach to study potential relationships between muscle fiber subtypes and vitamin D receptor expression...
  45. doi request reprint Renal function in patients treated with cinacalcet for persistent hyperparathyroidism after kidney transplantation
    Jana Henschkowski
    Center on Aging and Mobility, University Hospital, University of Zurich, Ramistrasse 100, Switzerland
    Kidney Blood Press Res 34:97-103. 2011
    ..We aimed to assess the association of cinacalcet with a decrease in renal function based on a meta-analysis of observational studies in kidney transplant patients with persistent HPT...
  46. ncbi request reprint Validity of a simple Internet-based outcome-prediction tool in patients with total hip replacement: a pilot study
    Cornel Stöckli
    Department of Rheumatology, Triemli City Hospital, Zurich, Switzerland
    J Telemed Telecare 20:117-22. 2014
    ..This may have been partly due to early complications after surgery. However, the outcome-prediction tool may be useful in helping patients to become better informed about the realistic outcome of their THR...
  47. ncbi request reprint Association between serum concentrations of 25-hydroxyvitamin D3 and periodontal disease in the US population
    Thomas Dietrich
    Department of Periodontology and the Department of Oral Surgery and Oral Radiology, Charite, Humboldt University of Berlin, Germany
    Am J Clin Nutr 80:108-13. 2004
    ..Periodontal disease (PD) is a common chronic inflammatory disease and an important risk factor for tooth loss. Vitamin D might affect periodontal disease risk via an effect on bone mineral density (BMD) or via immunomodulatory effects...
  48. ncbi request reprint Sunlight, tanning booths, and vitamin D
    Henry W Lim
    Department of Dermatology at Henry Ford Hospital, Detroit, Michigan, USA
    J Am Acad Dermatol 52:868-76. 2005