T Binzoni

Summary

Affiliation: University of Geneva
Country: Switzerland

Publications

  1. ncbi request reprint Light transport in tissue by 3D Monte Carlo: influence of boundary voxelization
    T Binzoni
    Centre Medical Universitaire, 1, r Michel Servet, Département des Neurosciences Fondamentales, University of Geneva, 1211 Geneve 4, Switzerland
    Comput Methods Programs Biomed 89:14-23. 2008
  2. ncbi request reprint Energy metabolism and interstitial fluid displacement in human gastrocnemius during short ischemic cycles
    T Binzoni
    Departments of Physiology and Radiology, Faculty of Medicine, University of Geneva, 1211 Geneva 4, Switzerland
    J Appl Physiol 85:1244-51. 1998
  3. ncbi request reprint The use of the Henyey-Greenstein phase function in Monte Carlo simulations in biomedical optics
    T Binzoni
    Département des Neurosciences Fondamentales, Centre Medical Universitaire, University of Geneva, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
    Phys Med Biol 51:N313-22. 2006
  4. ncbi request reprint Muscle O(2) consumption by NIRS: a theoretical model
    T Binzoni
    Departments of Physiology and Radiology, Faculty of Medicine, University of Geneva, 1211 Geneva 4, Switzerland
    J Appl Physiol 87:683-8. 1999
  5. ncbi request reprint Translational and Brownian motion in laser-Doppler flowmetry of large tissue volumes
    T Binzoni
    Department of Physiology, Faculty of Medicine, University of Geneva, Switzerland
    Phys Med Biol 49:5445-58. 2004
  6. ncbi request reprint Temperature dependence of human gastrocnemius pH and high-energy phosphate concentration by noninvasive techniques
    T Binzoni
    Depts of Radiology and Physiology, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    Magn Reson Med 43:611-4. 2000
  7. doi request reprint Full-field laser-Doppler imaging and its physiological significance for tissue blood perfusion
    T Binzoni
    Département des Neurosciences Fondamentales, University of Geneva, Switzerland
    Phys Med Biol 53:6673-94. 2008
  8. ncbi request reprint Absorption and scattering coefficient dependence of laser-Doppler flowmetry models for large tissue volumes
    T Binzoni
    Département de Neurosciences Fondamentales, Faculty of Medicine, University of Geneva, Switzerland
    Phys Med Biol 51:311-33. 2006
  9. ncbi request reprint Age dependence of human gastrocnemius Mg2+: fitting 31P-NMR spectra using quantum mechanics-based prior knowledge
    T Binzoni
    Departments of Physiology and Radiology, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    J Physiol Anthropol Appl Human Sci 20:275-83. 2001
  10. ncbi request reprint Determinants of peak muscle power: effects of age and physical conditioning
    G Ferretti
    Departement de Physiologie, Centre Medical Universitaire, Geneva, Switzerland
    Eur J Appl Physiol Occup Physiol 68:111-5. 1994

Detail Information

Publications36

  1. ncbi request reprint Light transport in tissue by 3D Monte Carlo: influence of boundary voxelization
    T Binzoni
    Centre Medical Universitaire, 1, r Michel Servet, Département des Neurosciences Fondamentales, University of Geneva, 1211 Geneve 4, Switzerland
    Comput Methods Programs Biomed 89:14-23. 2008
    ....
  2. ncbi request reprint Energy metabolism and interstitial fluid displacement in human gastrocnemius during short ischemic cycles
    T Binzoni
    Departments of Physiology and Radiology, Faculty of Medicine, University of Geneva, 1211 Geneva 4, Switzerland
    J Appl Physiol 85:1244-51. 1998
    ..The techniques developed in the present study may be useful in identifying protocols suitable for skeletal muscle preconditioning and to explain the functional basis of this procedure...
  3. ncbi request reprint The use of the Henyey-Greenstein phase function in Monte Carlo simulations in biomedical optics
    T Binzoni
    Département des Neurosciences Fondamentales, Centre Medical Universitaire, University of Geneva, 1 rue Michel Servet, 1211 Geneva 4, Switzerland
    Phys Med Biol 51:N313-22. 2006
    ..g. g = 0.98) the two methods give completely different results...
  4. ncbi request reprint Muscle O(2) consumption by NIRS: a theoretical model
    T Binzoni
    Departments of Physiology and Radiology, Faculty of Medicine, University of Geneva, 1211 Geneva 4, Switzerland
    J Appl Physiol 87:683-8. 1999
    ..The use of a series of experimental protocols obtained at different levels of mechanical power, rather than repetitions of the same load, appears to be the most suitable procedure...
  5. ncbi request reprint Translational and Brownian motion in laser-Doppler flowmetry of large tissue volumes
    T Binzoni
    Department of Physiology, Faculty of Medicine, University of Geneva, Switzerland
    Phys Med Biol 49:5445-58. 2004
    ..A correct way to subtract the biological zero from the LDF data is also proposed. The findings should help in the design of improved LDF instruments and in the interpretation of experimental data...
  6. ncbi request reprint Temperature dependence of human gastrocnemius pH and high-energy phosphate concentration by noninvasive techniques
    T Binzoni
    Depts of Radiology and Physiology, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    Magn Reson Med 43:611-4. 2000
    ..016+/-0.001 pH degrees C(-1)). These findings should be of value when dealing with muscle physiology in extreme environments or clinical applications of hypothermia...
  7. doi request reprint Full-field laser-Doppler imaging and its physiological significance for tissue blood perfusion
    T Binzoni
    Département des Neurosciences Fondamentales, University of Geneva, Switzerland
    Phys Med Biol 53:6673-94. 2008
    ..Further improvements on detectors' sampling rate will overcome this limitation...
  8. ncbi request reprint Absorption and scattering coefficient dependence of laser-Doppler flowmetry models for large tissue volumes
    T Binzoni
    Département de Neurosciences Fondamentales, Faculty of Medicine, University of Geneva, Switzerland
    Phys Med Biol 51:311-33. 2006
    ..The simplified model does not need knowledge of the tissue optical parameters and thus should allow the development of very simple and cost-effective LDF hardware...
  9. ncbi request reprint Age dependence of human gastrocnemius Mg2+: fitting 31P-NMR spectra using quantum mechanics-based prior knowledge
    T Binzoni
    Departments of Physiology and Radiology, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    J Physiol Anthropol Appl Human Sci 20:275-83. 2001
    ..The hypothesis can be put forward that during aging insufficient intake and/or increased depletion of Mg2+ (e.g., intestinal hypoabsorption or urinary leakage) may affect the musculoskeletal system...
  10. ncbi request reprint Determinants of peak muscle power: effects of age and physical conditioning
    G Ferretti
    Departement de Physiologie, Centre Medical Universitaire, Geneva, Switzerland
    Eur J Appl Physiol Occup Physiol 68:111-5. 1994
    ..An important role may be played by hormonal, particularly at puberty, and neural factors...
  11. ncbi request reprint Influence of repeated ischaemia/reperfusion cycles (ischaemic preconditioning) on human calf energy metabolism by simultaneous near infrared spectroscopy, 31P-NMR and 23Na-NMR measurements
    T Binzoni
    Department of Physiology, University of Geneva, Switzerland
    Adv Exp Med Biol 428:533-8. 1997
  12. ncbi request reprint Anisotropic photon migration in human skeletal muscle
    T Binzoni
    Département de Neurosciences Fondamentales, University of Geneva, Switzerland
    Phys Med Biol 51:N79-90. 2006
    ..In other words, the observed regional differences might not only be physiological differences but also optical artefacts...
  13. ncbi request reprint Human calf microvascular compliance measured by near-infrared spectroscopy
    T Binzoni
    Departments of Physiology and Radiology, Faculty of Medicine, University of Geneva, 1211 Geneva 4, Switzerland
    J Appl Physiol 88:369-72. 2000
    ..However, by following the changes in oxy- and deoxyhemoglobin in the P range -16 to 100 mmHg, it appears to be possible to assess the characteristics of the vasomotor response of the arteriolar system...
  14. ncbi request reprint Mapping human skeletal muscle perforator vessels using a quantum well infrared photodetector (QWIP) might explain the variability of NIRS and LDF measurements
    T Binzoni
    Department of Radiology, Faculty of Medicine, University of Geneva, Switzerland
    Phys Med Biol 49:N165-73. 2004
    ....
  15. ncbi request reprint Maximal lactic capacity at altitude: effect of bicarbonate loading
    B Kayser
    Departement de Physiologie, Centre Medical Universitaire, Geneva, Switzerland
    J Appl Physiol 75:1070-4. 1993
    ..001). [La]max increased from 12.86 +/- 1.45 mM in C to 16.63 +/- 1.76 mM in B (P < 0.01) at sea level and from 6.85 +/- 1.40 mM in C to 7.95 +/- 1.74 mM in B (NS) at altitude.(ABSTRACT TRUNCATED AT 250 WORDS)..
  16. ncbi request reprint The contribution of NMR, NIRS and their combination to the functional assessment of human muscle
    P Cerretelli
    Department of Physiology, University of Geneva, Switzerland
    Int J Sports Med 18:S270-9. 1997
    ..The concomitant use of the above techniques is expected to provide a synergic functional picture of the human muscle that is complementary to the structural and ultrastructural microscopic approach...
  17. pmc In vivo human gastrocnemius architecture with changing joint angle at rest and during graded isometric contraction
    M V Narici
    Reparto di Fisiologia Istituto di Tecnologie Biomediche Avanzate, Consiglio Nazionale dell Ricerche, Milano, Italy
    J Physiol 496:287-97. 1996
    ..The extrapolation of muscle architectural data obtained from cadavers to in vivo conditions should be made only for matching muscle lengths...
  18. ncbi request reprint Human intramuscular temperature and heat flow transients at rest
    T Binzoni
    Department of Radiology, Hopital Cantonal Universitaire de Geneve, Switzerland
    J Appl Physiol 79:1736-43. 1995
    ..In conclusion, MRI is indeed a powerful technique, useful to study the determinants of muscle temperature and heat flow changes in space and time...
  19. ncbi request reprint Human tibia bone marrow blood perfusion by non-invasive near infrared spectroscopy: a new tool for studies on microgravity
    T Binzoni
    Department of Radiology, Geneva University Hospital, Switzerland
    J Gravit Physiol 9:P183-4. 2002
    ..The results define a "normal" baseline and demonstrate the sensitivity of the method to PI changes. The present technique should allow one to investigate physio-pathological effects induced by microgravity on tibia BM blood perfusion...
  20. doi request reprint Detection limits of multi-spectral optical imaging under the skin surface
    T Binzoni
    Département des Neurosciences Fondamentales, University of Geneva, Switzerland
    Phys Med Biol 53:617-36. 2008
    ..An increase in the concentration of a given molecule may produce different contrast, independently of the depth, depending on the characteristics of the skin layer where this change occurs...
  21. ncbi request reprint Human gastrocnemius medialis pennation angle as a function of age: from newborn to the elderly
    T Binzoni
    Department of Radiology, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    J Physiol Anthropol Appl Human Sci 20:293-8. 2001
    ..The present findings indicate that F theta is not a constant parameter but evolves, as is the case for bone length and height, as a function of age...
  22. ncbi request reprint Metabolic studies of human skeletal muscle by near infrared spectroscopy: possible applications in space research
    T Binzoni
    University of Geneva, Department of Radiology, Switzerland
    Int J Sports Med 18:S312-4. 1997
  23. ncbi request reprint Autonomic nervous control of heart rate at altitude (5050 m)
    C C Farinelli
    Department of Physiology, University of Geneva, Switzerland
    Eur J Appl Physiol Occup Physiol 69:502-7. 1994
    ..These results corroborate the reported reduced sensitivity of the heart to adrenergic drive in chronic hypoxia, which may, at least in part, explain the decreased maximal heart rate in altitude-acclimatized human subjects...
  24. ncbi request reprint Non-invasive laser Doppler perfusion measurements of large tissue volumes and human skeletal muscle blood RMS velocity
    T Binzoni
    Department of Radiology, Faculty of Medicine, University of Geneva, Switzerland
    Phys Med Biol 48:2527-49. 2003
    ..At very large optode spacings or very high moving particle densities, the theory developed here would need to be amended to take into account second-order effects...
  25. ncbi request reprint Local temperature changes and human skeletal muscle metabolism
    T Binzoni
    Departments of Radiology and Physiology, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    J Physiol Anthropol Appl Human Sci 20:159-74. 2001
    ..A short comment on skeletal muscle temperature measurement techniques, on humans, is also included...
  26. ncbi request reprint Dynamic phosphorus-31 spectroscopy after fructose load in experimental biliary liver cirrhosis
    J P Vallee
    Department of Radiology, University of Geneva, Switzerland
    Acad Radiol 4:26-34. 1997
    ..The authors investigated the usefulness of dynamic phosphorus-31 magnetic resonance (MR) spectroscopy in the assessment of hepatic function by studying the effect of a fructose load on a rat model of liver cirrhosis...
  27. ncbi request reprint Step vs. progressive exercise: the kinetics of phosphocreatine hydrolysis in human muscle
    T Binzoni
    Department of Physiology, University of Geneva, Switzerland
    Acta Physiol Scand 159:209-15. 1997
    ....
  28. ncbi request reprint Phosphocreatine hydrolysis by 31P-NMR at the onset of constant-load exercise in humans
    T Binzoni
    Department of Physiology, Centre Medical Universitaire, Geneva, Switzerland
    J Appl Physiol 73:1644-9. 1992
    ....
  29. ncbi request reprint Standardisation of 31phosphorus-nuclear magnetic resonance spectroscopy determinations of high energy phosphates in humans
    L Gariod
    Departement de Physiologie, Centre Medical Universitaire, Geneva, Switzerland
    Eur J Appl Physiol Occup Physiol 68:107-10. 1994
    ..The [ATP] and [PC] were not statistically different in the groups investigated...
  30. ncbi request reprint Bioenergetic approach to transfer function of human skeletal muscle
    T Binzoni
    Department of Physiology, University of Geneva, Switzerland
    J Appl Physiol 77:1784-9. 1994
    ..g., skeletal, heart, trained vs. untrained), 5) it allows one to interpret correctly the significance of the oxygen consumption kinetics in the rest-to-work transient at the lung level, and 6) it is conceived for in vivo applications...
  31. ncbi request reprint Muscle energetics by 31P-NMRS: recent developments and possible applications in space research
    P Cerretelli
    University of Geneva, Department of Physiology, Switzerland
    Int J Sports Med 18:S306-7. 1997
  32. ncbi request reprint A new combined deep-body-temperature/NIRs probe for noninvasive metabolic measurements on human skeletal muscle
    T Binzoni
    Department of Physiology, University of Geneva, Switzerland
    Adv Exp Med Biol 471:623-9. 1999
  33. ncbi request reprint Muscle 31P-NMR in humans: estimate of bias and qualitative assessment of ATPase activity
    T Binzoni
    Department of Physiology, Centre Medical Universitaire, Geneva, Switzerland
    J Appl Physiol 71:1700-4. 1991
    ..g., during transition from rest to work and vice versa) may represent an index of transient changes of kappa 2...
  34. ncbi request reprint Alpha-motoneuron excitability at high altitude
    B Kayser
    Departement de Physiologie, Centre Medical Universitaire, Geneva, Switzerland
    Eur J Appl Physiol Occup Physiol 66:1-4. 1993
    ..The thresholds of both responses and the gain of the M-response were unaltered. The gain of the H-response was significantly higher at altitude when compared to sea level.(ABSTRACT TRUNCATED AT 250 WORDS)..
  35. ncbi request reprint Fatigue and exhaustion in chronic hypobaric hypoxia: influence of exercising muscle mass
    B Kayser
    Departement de Physiologie, Centre Medical Universitaire, Geneva, Switzerland
    J Appl Physiol 76:634-40. 1994
    ..By contrast, at HA, for similar t(ex), leg exercise had to be performed at the same relative (i.e., prevailing maximal O2 uptake) but lower absolute load (approximately equal to 80% of SL).(ABSTRACT TRUNCATED AT 250 WORDS)..
  36. ncbi request reprint Comment on 'the use of the Henyey-Greenstein phase function in Monte Carlo simulations in biomedical optics'
    T Binzoni
    Phys Med Biol 51:L39-41. 2006
    ..The exact definition for the probability density function for the deflection angle, in the case of the Henyey-Greenstein model, is also given...