Gilles Bertschy

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi [Psychiatry]
    G Bertschy
    Service de Psychiatrie Adulte, HUG, Chene Bourg
    Rev Med Suisse 2:61-6. 2006
  2. ncbi Induction of a mixed depressive episode during rTMS treatment in a patient with refractory major depression
    Fady Rachid
    Division of Adult Psychiatry, University Hospitals of Geneva, Switzerland
    World J Biol Psychiatry 7:261-4. 2006
  3. ncbi [Resistant depression]
    Gilles Bertschy
    Departement de Psychiatrie, HUG, 2, chemin du Petit Bel Air, Chene Bourg
    Rev Med Suisse 3:2072-4, 2076-7. 2007
  4. ncbi Trazodone addition for insomnia in venlafaxine-treated, depressed inpatients: a semi-naturalistic study
    Gilles Bertschy
    Department of Psychiatry, University Hospital and University of Geneva, Geneva, Switzerland
    Pharmacol Res 51:79-84. 2005
  5. ncbi Phenomenology of mixed states: a principal component analysis study
    G Bertschy
    Division of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland
    Bipolar Disord 9:907-12. 2007
  6. doi Frequency of dysphoria and mixed states
    G Bertschy
    Division of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland
    Psychopathology 41:187-93. 2008
  7. ncbi Lithium augmentation in venlafaxine non-responders: an open study
    G Bertschy
    Clinic of Adult Psychiatry, Department of Psychiatry, Geneva University, 2 ch du Petit Bel Air, Chene Bourg, 1225 Geneva, Switzerland
    Eur Psychiatry 18:314-7. 2003
  8. doi Self-rated residual symptoms do not predict 1-year recurrence of depression
    G Bertschy
    Division of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, 2, chemin du Petit Bel Air, 1225 Chene Bourg, Geneva, Switzerland
    Eur Psychiatry 25:52-7. 2010
  9. doi Salivary cortisol profiles in patients remitted from recurrent depression: one-year follow-up of a mindfulness-based cognitive therapy trial
    Marianne Gex-Fabry
    Department of Mental Health and Psychiatry, Geneva University Hospitals, 2 Chemin du Petit Bel Air, CH 1225 Chene Bourg, Geneva, Switzerland
    J Psychiatr Res 46:80-6. 2012
  10. ncbi The DEX/CRH neuroendocrine test and the prediction of depressive relapse in remitted depressed outpatients
    Jean Michel Aubry
    Department of Psychiatry, Adult Psychiatric Service Secteur 2, 16 18 Boulevard St Georges, CH 1205 Geneva, Switzerland
    J Psychiatr Res 41:290-4. 2007

Detail Information

Publications43

  1. ncbi [Psychiatry]
    G Bertschy
    Service de Psychiatrie Adulte, HUG, Chene Bourg
    Rev Med Suisse 2:61-6. 2006
    ..We also report two synthesis concerning the latest developments in the fields of cognitive psychotherapy for depressive disorders (rather stimulating news) and of pharmacotherapy for borderline personality disorders (no breaking news)...
  2. ncbi Induction of a mixed depressive episode during rTMS treatment in a patient with refractory major depression
    Fady Rachid
    Division of Adult Psychiatry, University Hospitals of Geneva, Switzerland
    World J Biol Psychiatry 7:261-4. 2006
    ..Therefore, caution should be exercised among clinicians using this experimental procedure, particularly in the treatment of bipolar depressed patients...
  3. ncbi [Resistant depression]
    Gilles Bertschy
    Departement de Psychiatrie, HUG, 2, chemin du Petit Bel Air, Chene Bourg
    Rev Med Suisse 3:2072-4, 2076-7. 2007
    ..In parallel some other issues have to be considered (therapeutic compliance, comorbidities, pervasive psychosocial stress factors, associated somatic disorders) and treatment should always include psychotherapy and support to the family...
  4. ncbi Trazodone addition for insomnia in venlafaxine-treated, depressed inpatients: a semi-naturalistic study
    Gilles Bertschy
    Department of Psychiatry, University Hospital and University of Geneva, Geneva, Switzerland
    Pharmacol Res 51:79-84. 2005
    ..05). Thus, trazodone is probably used for patients who develop not only insomnia, but also inner tension/anxiety during venlafaxine treatment. However, it alleviates only the first symptom, not the second...
  5. ncbi Phenomenology of mixed states: a principal component analysis study
    G Bertschy
    Division of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland
    Bipolar Disord 9:907-12. 2007
    ..To contribute to the definition of external and internal limits of mixed states and study the place of dysphoric symptoms in the psychopathology of mixed states...
  6. doi Frequency of dysphoria and mixed states
    G Bertschy
    Division of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland
    Psychopathology 41:187-93. 2008
    ....
  7. ncbi Lithium augmentation in venlafaxine non-responders: an open study
    G Bertschy
    Clinic of Adult Psychiatry, Department of Psychiatry, Geneva University, 2 ch du Petit Bel Air, Chene Bourg, 1225 Geneva, Switzerland
    Eur Psychiatry 18:314-7. 2003
    ..Two patients had to stop lithium for a possible moderate serotonin syndrome and five patients became responders, including one dramatic response and two semi-rapid responses...
  8. doi Self-rated residual symptoms do not predict 1-year recurrence of depression
    G Bertschy
    Division of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, 2, chemin du Petit Bel Air, 1225 Chene Bourg, Geneva, Switzerland
    Eur Psychiatry 25:52-7. 2010
    ..In the absence of a specific instrument for the assessment of residual symptoms, a new 25-item Depression Residual Symptom Scale (DRSS) was elaborated and tested for recurrence prediction over a 1-year follow-up...
  9. doi Salivary cortisol profiles in patients remitted from recurrent depression: one-year follow-up of a mindfulness-based cognitive therapy trial
    Marianne Gex-Fabry
    Department of Mental Health and Psychiatry, Geneva University Hospitals, 2 Chemin du Petit Bel Air, CH 1225 Chene Bourg, Geneva, Switzerland
    J Psychiatr Res 46:80-6. 2012
    ..Further research is needed to address the scar hypothesis of diminished HPA activity with a longer, chronic course of depression...
  10. ncbi The DEX/CRH neuroendocrine test and the prediction of depressive relapse in remitted depressed outpatients
    Jean Michel Aubry
    Department of Psychiatry, Adult Psychiatric Service Secteur 2, 16 18 Boulevard St Georges, CH 1205 Geneva, Switzerland
    J Psychiatr Res 41:290-4. 2007
    ..These results suggest that in outpatients who are in clinical remission from a major depressive episode, high delta and AUC values in the DEX/CRH test compared to controls subjects can be associated with a higher risk of relapse...
  11. doi CYP2D6 and ABCB1 genetic variability: influence on paroxetine plasma level and therapeutic response
    Marianne Gex-Fabry
    Division of Adult Psychiatry, Department of Psychiatry, Geneva University Hospitals, Chene Bourg, Switzerland
    Ther Drug Monit 30:474-82. 2008
    ..The hypothesis that permeability glycoprotein activity might be a relevant predictor of therapeutic response deserves to be further investigated while controlling for pharmacokinetic variability...
  12. ncbi Time course of clinical response to venlafaxine: relevance of plasma level and chirality
    Marianne Gex-Fabry
    Clinical Research Unit, Department of Psychiatry, 2 Chemin du Petit Bel Air, 1225 Chene Bourg, Switzerland
    Eur J Clin Pharmacol 59:883-91. 2004
    ....
  13. ncbi Time course of response to paroxetine: influence of plasma level
    Marianne Gex-Fabry
    Service of Adult Psychiatry, Department of Psychiatry, Geneva University Hospitals, 2 Chemin du Petit Bel Air, CH 1225 Chene Bourg, Switzerland
    Prog Neuropsychopharmacol Biol Psychiatry 31:892-900. 2007
    ..005). The present study supports the hypothesis that higher paroxetine concentration might contribute to hasten relief of depressive symptoms in severely depressed patients...
  14. doi The cortisol awakening response in patients remitted from depression
    Jean Michel Aubry
    Department of Psychiatry, Geneva University Hospital, Bipolar Program, 6 8 rue du 31 Décembre, 1207 Geneva, Switzerland
    J Psychiatr Res 44:1199-204. 2010
    ..007), while a 21% AUC decrease was associated with a 1-h longer sleep duration (p<0.001). In future studies, detection of between-group differences might benefit from adjusting for sleep duration and other possible confounders...
  15. ncbi Partial normalization of serum brain-derived neurotrophic factor in remitted patients after a major depressive episode
    Nicola Gervasoni
    Department of Psychiatry, Geneva University Hospital, 16 18 boulevard Saint Georges, CH 1205 Geneva, Switzerland
    Neuropsychobiology 51:234-8. 2005
    ..These results suggest that antidepressant treatment has a positive effect on serum BDNF levels and support the hypothesis of neurotrophic factor involvement in affective disorders...
  16. doi Clinical and genetic correlates of suicidal ideation during antidepressant treatment in a depressed outpatient sample
    Nader Perroud
    Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland
    Pharmacogenomics 12:365-77. 2011
    ..This study investigated clinical and genetic predictors of increasing suicidal ideation during antidepressant treatment...
  17. pmc Depression relapse prophylaxis with Mindfulness-Based Cognitive Therapy: replication and extension in the Swiss health care system
    Guido Bondolfi
    Department of Psychiatry, Geneva University Hospital, Switzerland
    J Affect Disord 122:224-31. 2010
    ..The present study is the first independent replication trial comparing MBCT+TAU to TAU alone across both language and culture (Swiss health care system)...
  18. ncbi [Trends in psychiatry]
    Nicola Gervasoni
    Service de Psychiatrie Adulte, HUG, Geneve
    Rev Med Suisse 4:158-60, 162-5. 2008
    ..3) The potential efficacy of dawn simulation and high density negative air ionization in seasonal depression...
  19. doi Smoking in psychiatric inpatients: association with working status, diagnosis, comorbid substance abuse and history of suicide attempts
    Ineke Keizer
    Division of Adult Psychiatry, Department of Psychiatry, HUG University Hospitals of Geneva, Site de Belle Idée, Les Voirons, Chemin du Petit Bel Air 2, Chene Bourg, Switzerland
    Addict Behav 34:815-20. 2009
    ..These results underline the importance of taking into account socio-demographic factors and substance use comorbidity in designing targeted interventions to reduce smoking in psychiatric patients...
  20. ncbi Possible induction of mania or hypomania by atypical antipsychotics: an updated review of reported cases
    Fady Rachid
    Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland
    J Clin Psychiatry 65:1537-45. 2004
    ..Between 1994 and 1999, 26 cases of manic and hypomanic syndromes were reported with olanzapine and risperidone and were described in a previous review article...
  21. ncbi Body dysmorphic disorder, psychosis and insight: a report of four cases
    Juan Pablo Lucchelli
    Adult Psychiatry Service, University Hospital of Geneva, Geneva, Switzerland
    Psychopathology 39:130-5. 2006
    ....
  22. ncbi A retrospective comparison of inpatients with mixed and pure depression
    Séverine Ducrey
    Clinic of Adult Psychiatry, Department of Psychiatry, Geneva University Hospitals, Geneva, Switzerland
    Psychopathology 36:292-8. 2003
    ..These last two points remain significant even when we control for the effect of the association with bipolarity...
  23. ncbi A stepwise drug treatment algorithm to obtain complete remission in depression: a Geneva study
    G Bondolfi
    Hopitaux Universitaires de Geneve, Departement de Psychiatrie, Service de Psychiatrie Adulte
    Swiss Med Wkly 136:78-85. 2006
    ..We compare several treatment options for SSRI (selective serotonin reuptake inhibitor) non-responders and test the feasibility of the algorithm in clinical conditions...
  24. ncbi [Psychiatry]
    J M Aubry
    Service de Psychiatrie Adulte, HUG, Geneve
    Rev Med Suisse 3:161-7. 2007
    ..Its also reviews two questions of present interest: the use of the second generation antipsychotics for the treatment of bipolar depression and the concept of bipolar disorders in children...
  25. ncbi Possible induction of mania and hypomania by olanzapine or risperidone: a critical review of reported cases
    J M Aubry
    Departement de Psychiatrie, Clinique de Psychiatrie adulte 2, Chene Bourg, Geneva, Switzerland
    J Clin Psychiatry 61:649-55. 2000
    ..Risperidone and olanzapine are atypical antipsychotics that are now widely used in clinical practice...
  26. ncbi The effect of fluoxetine on the pharmacokinetics and safety of risperidone in psychotic patients
    G Bondolfi
    Dépatrement universitaire de psychiatrie adulte, Site de Cery, Pirlly Lausanne, Switzerland
    Pharmacopsychiatry 35:50-6. 2002
    ..The severity and incidence of extrapyramidal symptoms and adverse events did not significantly increase when fluoxetine was added...
  27. ncbi Lithium dose prediction based on 24 hours single dose levels: a prospective evaluation
    N Gervasoni
    Departement de Psychiatrie, Clinique de Psychiatrie Adulte Programme Dépression, Hopitaux Universitaires de Geneve, Domaine de Belle Idée, 16 18, bd Saint Georges, CH 1205 Geneva, Switzerland
    Pharmacol Res 48:649-53. 2003
    ..Although there was no control group, the prediction test often allowed us to use a higher dose than the usual fixed dose whose amount is limited by the risk of overdosing for the slower metabolizers...
  28. ncbi Cortisol responses to combined dexamethasone/CRH test in outpatients with a major depressive episode
    Nicola Gervasoni
    Adult Psychiatric Service, Department of Psychiatry, Geneva University Hospital, 16 18 bd Saint Georges, 1205 Geneva, Switzerland
    J Psychiatr Res 38:553-7. 2004
    ..In future studies, it could be interesting to use this test more specifically by dividing ambulatory patients into subgroups according to their past depressive history. It could also be interesting to measure the ACTH level...
  29. doi Melatonin in treatment of chronic sleep disorders in adults with autism: a retrospective study
    Giuliana Galli-Carminati
    Division of Adult Psychiatry, Department of Psychiatry, University Hospital of Geneva, Geneva, Switzerland
    Swiss Med Wkly 139:293-6. 2009
    ..The evidence for its efficacy, potential adverse effects and drug interactions are reviewed in the context of prescription of melatonin to patients with autism...
  30. ncbi [Mood disorders in perimenopausal women: hormone replacement or antidepressant therapy?]
    Gilles Bertschy
    Service de Psychiatrie Adulte, Departement de Psychiatrie, HUG, 1211 Geneve 14
    Rev Med Suisse 1:2155-6, 2159-61. 2005
    ..When the depression is major, present data do not support the possibility of using hormone replacement therapy instead of antidepressants...
  31. ncbi Low-dose venlafaxine in three adolescents and young adults with autistic disorder improves self-injurious behavior and attention deficit/hyperactivity disorders (ADHD)-like symptoms
    Giuliana Galli Carminati
    Division of Adult Psychiatry, Department of Psychiatry, Psychiatry of Mental Development Unit, University Hospitals of Geneva
    Prog Neuropsychopharmacol Biol Psychiatry 30:312-5. 2006
    ..75 mg/day). Follow-ups occurred respectively 18, 36 and 6 months after treatment initiation, making it possible to observe the stability of the clinical improvement in these cases...
  32. ncbi A theoretical reappraisal of mixed states: dysphoria as a third dimension
    A Dayer
    Department of Psychiatry, Clinic of Adult Psychiatry II, Geneva, Switzerland
    Bipolar Disord 2:316-24. 2000
    ..These subtypes of mixed states will need validation through prospective clinical studies. Biological differences, differential outcome over time, and differential response to treatment will be important validation criteria...
  33. ncbi Steady-state concentration of venlafaxine enantiomers: model-based analysis of between-patient variability
    Marianne Gex-Fabry
    Clinical Research Unit, Department of Psychiatry, Geneva University Hospitals, 2 Chemin du Petit Bel Air, 1225 Chene Bourg, Switzerland
    Eur J Clin Pharmacol 58:323-31. 2002
    ....
  34. ncbi [The major depression with psychotic symptoms]
    N Gervasoni
    Centre de thérapies brèves, Service de Psychiatrie Adulte, Departement de Psychiatrie, HUG, rue des Bains 35, 1205 Geneve
    Rev Med Suisse 4:1984-7. 2008
    ..Concerning the pharmacological treatment, the discussion is still open about the necessity of the association of an antipsychotic or the choice of the antidepressant...
  35. ncbi Mania resulting from continuous positive airways pressure in a depressed man with sleep apnea syndrome
    H Hilleret
    Department of Psychiatry, University Hospital, Geneva, Switzerland
    Neuropsychobiology 43:221-4. 2001
    ..A few days after starting CPAP, he presented a mood switch, first hypomanic, then mixed. The authors discuss the contribution of the sleep apnea syndrome to the appearance and the maintenance of the depressive disorder...
  36. ncbi [Translation and validation of a French version of the Young Mania Rating Scale (YMRS)]
    S Favre
    Hopital Cantonal Universitaire de Geneve, Departement de Psychiatrie, Clinique de Psychiatrie Adulte, Belle Idée Les Voirons, 2, Ch du petit Bel Air, CH 1225 Chêne Bourg GE
    Encephale 29:499-505. 2003
    ..This should allow its future use for international comparison studies...
  37. ncbi Safety and efficacy of repetitive transcranial magnetic stimulation in the treatment of depression: a critical appraisal of the last 10 years
    F Rachid
    Departement de Psychiatrie, Service de Psychiatrie Adulte, Hopitaux Universitaires de Geneve, consultation de la jonction, 16 18, boulevard Saint Georges, 1205 Geneve, Switzerland
    Neurophysiol Clin 36:157-83. 2006
    ....
  38. ncbi [Current topics in pharmacokinetics and pharmacogenetics of antidepressant drugs]
    M Gex-Fabry
    Service de Psychiatrie Adulte, Departement de Psychiatrie, HUG, Chene Bourg
    Rev Med Suisse 5:1808, 1810-3. 2009
    ..Current recommendations with respect to therapeutic drug monitoring of antidepressants and use of pharmacogenetic testing are then summarized...
  39. ncbi Decreased serum brain-derived neurotrophic factor levels in major depressed patients
    Felicien Karege
    Laboratory of Biochemistry, Division of Neuropsychiatry, Geneva University Hospitals, 2 Chemin du Petit Bel Air, CH 1225 Chene Bourg, Switzerland
    Psychiatry Res 109:143-8. 2002
    ..These results suggest that major depression is characterized by low serum BDNF levels and support the hypothesis of neurotrophic factor involvement in affective disorders...
  40. ncbi Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity
    Felicien Karege
    Service of Neuropsychiatry, Geneva University Hospitals Belle Idée, Chêne Bourg Geneva, Switzerland
    Biol Psychiatry 57:1068-72. 2005
    ..Decreased serum BDNF levels have been reported in major depression, but the cause of this decrease has not yet been investigated. The goal of this study was to assess blood BDNF and a platelet activation index, PF4...
  41. ncbi Missed Monday appointments
    Ariel Eytan
    Psychiatr Serv 56:613. 2005
  42. ncbi The efficiency of a carbamazepine-mianserin combination scheme in opiate detoxification
    Daniele F Zullino
    Division of Substance Abuse, University Department of Adult Psychiatry, Hôpital de Cery, CH 1008 Prilly Lausanne, Switzerland
    Hum Psychopharmacol 19:425-30. 2004
    ....
  43. ncbi [Electroconvulsive therapy: thoughts on a prohibited treatment]
    Jean Francois Etter
    Institut de Medecine Sociale et Preventive, Faculte de Medecine, Universite de Geneve, CMU, 1211 Geneve 4
    Rev Med Suisse 4:676-9. 2008