L Bernard

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi The inhibition of neutrophil antibacterial activity by ultra-high molecular weight polyethylene particles
    Louis Bernard
    Division of Orthopaedic Surgery, University Hospital of Geneva, Geneva, Switzerland
    Biomaterials 26:5552-7. 2005
  2. ncbi Outpatient parenteral antimicrobial therapy (OPAT) for the treatment of osteomyelitis: evaluation of efficacy, tolerance and cost
    L Bernard
    Division of Infectious Diseases, Raymond Poincaré Medical University, Garches, France
    J Clin Pharm Ther 26:445-51. 2001
  3. ncbi The value of suction drainage fluid culture during aseptic and septic orthopedic surgery: a prospective study of 901 patients
    L Bernard
    Division of Infectious Diseases, Geneva University Hospital, Geneva, Switzerland
    Clin Infect Dis 34:46-9. 2002
  4. ncbi Relationship between levels of indinavir in hair and virologic response to highly active antiretroviral therapy
    Louis Bernard
    Division of Infectious Diseases, Geneva University Hospital and Laboratoire de Virologie, Rue Micheli du Crest, CH 1211 Geneva, Switzerland
    Ann Intern Med 137:656-9. 2002
  5. ncbi Serotonin syndrome after concomitant treatment with linezolid and citalopram
    L Bernard
    Division of Orthopaedic Surgery, Geneva University Hospital, Geneva, Switzerland
    Clin Infect Dis 36:1197. 2003
  6. ncbi Value of preoperative investigations in diagnosing prosthetic joint infection: retrospective cohort study and literature review
    Louis Bernard
    Division of Infectious Diseases, Geneva University Hospital, Geneva, Switzerland
    Scand J Infect Dis 36:410-6. 2004
  7. ncbi Risk factors for treatment failure in orthopedic device-related methicillin-resistant Staphylococcus aureus infection
    T Ferry
    Infectious Diseases Unit, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland
    Eur J Clin Microbiol Infect Dis 29:171-80. 2010
  8. ncbi Successful treatment of Candida parapsilosis (fluconazole-resistant) osteomyelitis with caspofungin in a HIV patient
    L Legout
    Orthopaedic Surgery Service, University Hospital of Geneva, Switzerland
    Scand J Infect Dis 38:728-30. 2006
  9. ncbi [Outpatient parenteral antimicrobial therapy (OPAT) in bone and joint infections]
    T Galperine
    Unité de maladies infectieuses, Département de Médecine Aiguë Spécialisée, Assistance Publique Hopitaux de Paris, Hôpital Universitaire Raymond Poincaré, Universite de Versailles, Garches, France
    Med Mal Infect 36:132-7. 2006
  10. doi [Optimal duration of antibiotic therapy in osteomyelitis]
    L Bernard
    Service de Maladies Infectieuses, CHU R Poincaré, UVSQ, APHP, Garches, France
    Med Mal Infect 38:S108-9. 2008

Collaborators

Detail Information

Publications25

  1. ncbi The inhibition of neutrophil antibacterial activity by ultra-high molecular weight polyethylene particles
    Louis Bernard
    Division of Orthopaedic Surgery, University Hospital of Geneva, Geneva, Switzerland
    Biomaterials 26:5552-7. 2005
    ..01), but not with larger size. The results suggest that neutrophil functional defects triggered by the presence of UHMWP particles may potentially contribute to the susceptibility of loose implants to bacterial infections...
  2. ncbi Outpatient parenteral antimicrobial therapy (OPAT) for the treatment of osteomyelitis: evaluation of efficacy, tolerance and cost
    L Bernard
    Division of Infectious Diseases, Raymond Poincaré Medical University, Garches, France
    J Clin Pharm Ther 26:445-51. 2001
    ..To evaluate the feasibility, efficacy, and cost of outpatient parenteral antimicrobial therapy (OPAT) in the treatment of osteomyelitis...
  3. ncbi The value of suction drainage fluid culture during aseptic and septic orthopedic surgery: a prospective study of 901 patients
    L Bernard
    Division of Infectious Diseases, Geneva University Hospital, Geneva, Switzerland
    Clin Infect Dis 34:46-9. 2002
    ..We conclude that, for aseptic orthopedic surgery, SDC is not useful in detecting postoperative infection. However, for septic orthopedic surgery, it is of clinical importance...
  4. ncbi Relationship between levels of indinavir in hair and virologic response to highly active antiretroviral therapy
    Louis Bernard
    Division of Infectious Diseases, Geneva University Hospital and Laboratoire de Virologie, Rue Micheli du Crest, CH 1211 Geneva, Switzerland
    Ann Intern Med 137:656-9. 2002
    ..Suboptimal levels of antiretroviral drugs result in virologic failure in HIV-infected patients treated with highly active antiretroviral therapy (HAART)...
  5. ncbi Serotonin syndrome after concomitant treatment with linezolid and citalopram
    L Bernard
    Division of Orthopaedic Surgery, Geneva University Hospital, Geneva, Switzerland
    Clin Infect Dis 36:1197. 2003
    ....
  6. ncbi Value of preoperative investigations in diagnosing prosthetic joint infection: retrospective cohort study and literature review
    Louis Bernard
    Division of Infectious Diseases, Geneva University Hospital, Geneva, Switzerland
    Scand J Infect Dis 36:410-6. 2004
    ..Our study indicates that C-reactive protein and joint aspiration are the most useful tools to diagnose prosthetic joint infection even in situations of chronic infection (Coventry type II)...
  7. ncbi Risk factors for treatment failure in orthopedic device-related methicillin-resistant Staphylococcus aureus infection
    T Ferry
    Infectious Diseases Unit, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland
    Eur J Clin Microbiol Infect Dis 29:171-80. 2010
    ..2-16.3; P = 0.025) were independent predictors of treatment failure after debridement. Therapy using a combination of antimicrobials should be considered for patients with MRSA ODRI, especially when implant removal is not feasible...
  8. ncbi Successful treatment of Candida parapsilosis (fluconazole-resistant) osteomyelitis with caspofungin in a HIV patient
    L Legout
    Orthopaedic Surgery Service, University Hospital of Geneva, Switzerland
    Scand J Infect Dis 38:728-30. 2006
    ..We illustrate the likelihood of severe infections due fluconazole resistant C. parapsilosis after extensive fluconazole use and discuss the role of newer antifungal agents in the treatment of arthritis due to Candida spp...
  9. ncbi [Outpatient parenteral antimicrobial therapy (OPAT) in bone and joint infections]
    T Galperine
    Unité de maladies infectieuses, Département de Médecine Aiguë Spécialisée, Assistance Publique Hopitaux de Paris, Hôpital Universitaire Raymond Poincaré, Universite de Versailles, Garches, France
    Med Mal Infect 36:132-7. 2006
    ..In addition, OPAT is clearly more cost-effective than intravenous therapy provided in the hospital setting. Some diagnoses, such as cellulites, community-acquired pneumonia, and endocarditis may be managed with OPAT...
  10. doi [Optimal duration of antibiotic therapy in osteomyelitis]
    L Bernard
    Service de Maladies Infectieuses, CHU R Poincaré, UVSQ, APHP, Garches, France
    Med Mal Infect 38:S108-9. 2008
  11. ncbi Zenker's diverticulum associated with multilevel cervical osteomyelitis
    B Frot Martin
    Department of Radiology, , Garches, France
    Spine (Phila Pa 1976) 26:E193-7. 2001
    ..Management relies on appropriate antimicrobial therapy and surgical management of the diverticulum. The association of Zenker's diverticulum with vertebral osteomyelitis and discitis is a unique, previously undescribed situation...
  12. ncbi Bartonella henselae infection mimicking a splenic lymphoma
    D Ghez
    Service des Maladies Infectieuses et Tropicales, , , Garches, France
    Scand J Infect Dis 33:935-6. 2001
    ..Splenic cat-scratch disease is an exceptional diagnosis in adults and can easily be mistaken for a splenic lymphoma, thereby leading to an unnecessary splenectomy...
  13. pmc Recurrent osteomyelitis caused by infection with different bacterial strains without obvious source of reinfection
    Ilker Uckay
    Division of Infectious Diseases, Geneva University Hospital, Switzerland
    J Clin Microbiol 44:1194-6. 2006
    ..Formerly infected and altered bone surface might present a region of diminished resistance for a new infection...
  14. ncbi Suction drainage culture as a guide to effectively treat musculoskeletal infection
    Laurence Legout
    Orthopaedic Surgery Service, University Hospital of Geneva, Switzerland
    Scand J Infect Dis 38:341-5. 2006
    ..Similar results were obtained in patients with an infection in the presence of an implant. In conclusion, a negative SDC following surgery for a musculoskeletal infection is a strong indication of eventual outcome...
  15. ncbi Inactivation of a subpopulation of human neutrophils by exposure to ultrahigh-molecular-weight polyethylene wear debris
    Louis Bernard
    Service of Orthopaedic Surgery, Geneva University Hospital, Switzerland
    FEMS Immunol Med Microbiol 49:425-32. 2007
    ..In conclusion, engulfment of UHMWPE wear particles led to inactivation of S. aureus uptake in nearly half of the neutrophil population, which may potentially impair host clearance mechanisms against pyogenic infections...
  16. ncbi High versus standard dose vancomycin for osteomyelitis
    Emmanuelle Boffi El Amari
    Department of Medicine, Geneva University Hospital, Switzerland
    Scand J Infect Dis 36:712-7. 2004
    ..The best outcome was found in the subgroup of patients who received HD-CVI (HD-CVI vs SD-IVI, overall log rank p-value 0.02). HD-CVI treatment appears to provide an improved outcome with fewer adverse drug reactions...
  17. ncbi Comparative analysis and validation of different assays for glycopeptide susceptibility among methicillin-resistant Staphylococcus aureus strains
    Louis Bernard
    Division of Infectious Diseases, University Hospitals of Geneva, CH 1211, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    J Microbiol Methods 57:231-9. 2004
    ..Screening of decreased susceptibility to vancomycin or teicoplanin on V2-BHIA or T5-BHIA, respectively, may represent simple low-cost alternatives to Etest MICs, minimising the risk of missing potential GISA isolates...
  18. ncbi [Antibiotic therapy of osteoarticular infections in the adult]
    Tatiana Galperine
    Unité de maladies infectieuses, Département de Médecine Aiguë Spécialisée, hôpital universitaire Poincaré, Universite de Versailles, 92380 Garches
    Rev Prat 57:995-1002. 2007
    ..It is difficult to make evidence-based recommendations on the treatment of these infections, as very little high quality clinical evidence exists...
  19. ncbi [Bone and joint prosthesis infections]
    Louis Bernard
    Service de Maladies Infectieuses, Hopital Raymond Poincare, UVSQ, 92380 Garches
    Rev Prat 57:958-69. 2007
    ..In any scenario, a close collaboration between physicians and surgeons is essential to stop the infectious process...
  20. ncbi [Osteoarticular infections. New mangement challenges]
    Louis Bernard
    Unité de maladies infectieuses, CHU Raymond Poincaré, UVSQ, 92380 Garches
    Rev Prat 57:945-6. 2007
  21. ncbi The value of bacterial culture during clean orthopedic surgery: a prospective study of 1,036 patients
    Louis Bernard
    Orthopaedic Clinic, Division of Infectious Diseases, Geneva University Hospital, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    Infect Control Hosp Epidemiol 25:512-4. 2004
    ..To determine whether bacterial cultures of the wounds of patients undergoing clean orthopedic surgery would help predict infection...
  22. ncbi Effect of vancomycin therapy for osteomyelitis on colonization by methicillin-resistant Staphylococcus aureus: lack of emergence of glycopeptide resistance
    Louis Bernard
    Orthopedic Clinic, Geneva University Hospital, Geneva, Switzerland
    Infect Control Hosp Epidemiol 24:650-4. 2003
    ..In treating orthopedic infections, the long-term impact of vancomycin therapy on colonization by methicillin-resistant Staphylococcus aureus (MRSA) and the emergence of vancomycin-intermediate S. aureus is unknown...
  23. ncbi Prevention of urinary tract infection in spinal cord-injured patients: safety and efficacy of a weekly oral cyclic antibiotic (WOCA) programme with a 2 year follow-up--an observational prospective study
    Jerome Salomon
    Division of Infectious Diseases, Raymond Poincaré University Hospital AP HP, Garches, France
    J Antimicrob Chemother 57:784-8. 2006
    ..Recurrent UTI requires multiple courses of antibiotic therapy, markedly increasing the incidence of multidrug-resistant (MDR) bacteria...
  24. ncbi [Pathophysiology of infection on orthopedic biomaterials]
    Florence Ader
    Département de Médecine Aiguë Spécialisée, hôpital Raymond Poincaré AP HP, Université de Versailles Saint Quentin en Yvelines 104, Boulevard Raymond Poincare, 92380 Garches
    Presse Med 34:533-6. 2005
    ..Some bacterial sub-populations develop transitory resistance to bactericidal antibiotics in the presence of these materials...
  25. ncbi Trends in the treatment of orthopaedic prosthetic infections
    Louis Bernard
    Orthopaedic Clinic, Geneva University Hospital, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    J Antimicrob Chemother 53:127-9. 2004
    ....