Christian R Baumann

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi request reprint Normal CSF hypocretin-1 (orexin A) levels in dementia with Lewy bodies associated with excessive daytime sleepiness
    Christian R Baumann
    Neurology Department, University Hospital, Zurich, Switzerland
    Eur Neurol 52:73-6. 2004
  2. doi request reprint Traumatic brain injury and disturbed sleep and wakefulness
    Christian R Baumann
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    Neuromolecular Med 14:205-12. 2012
  3. ncbi request reprint [The neurotransmitter, hypocretin. An overview]
    C Baumann
    Neurologische Klinik, Universitatsspital Zurich
    Nervenarzt 75:317-23. 2004
  4. pmc Loss of hypocretin (orexin) neurons with traumatic brain injury
    Christian R Baumann
    Department of Neurology, University Hospital, Zurich, Switzerland
    Ann Neurol 66:555-9. 2009
  5. ncbi request reprint Lipoma on the corpus callosum in a patient with schizophrenia-like episode: is there a causal relationship?
    Christian R Baumann
    Department of Neurology, University Hospital, Zurich, Switzerland
    Cogn Behav Neurol 19:109-11. 2006
  6. doi request reprint Epidemiology, diagnosis and differential diagnosis in Parkinson's disease tremor
    Christian R Baumann
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    Parkinsonism Relat Disord 18:S90-2. 2012
  7. doi request reprint Sleep-wake disturbances 3 years after traumatic brain injury
    Julia Kempf
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    J Neurol Neurosurg Psychiatry 81:1402-5. 2010
  8. doi request reprint Sleep: approaching the fundamental questions
    Christian R Baumann
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    Curr Biol 18:R665-R667. 2008
  9. doi request reprint Multiple sleep latency measures in narcolepsy and behaviourally induced insufficient sleep syndrome
    Isabelle Marti
    Department of Neurology, University Hospital of Zurich, Zurich, Switzerland
    Sleep Med 10:1146-50. 2009
  10. doi request reprint Progressive dopamine and hypocretin deficiencies in Parkinson's disease: is there an impact on sleep and wakefulness?
    Miriam Wienecke
    Department of Neurology, University Hospital, Zurich, Switzerland
    J Sleep Res 21:710-7. 2012

Collaborators

Detail Information

Publications48

  1. ncbi request reprint Normal CSF hypocretin-1 (orexin A) levels in dementia with Lewy bodies associated with excessive daytime sleepiness
    Christian R Baumann
    Neurology Department, University Hospital, Zurich, Switzerland
    Eur Neurol 52:73-6. 2004
    ..In DLB, excessive daytime sleepiness, hallucinations and REM sleep behavior may occur in the absence of a detectable hypocretin deficiency...
  2. doi request reprint Traumatic brain injury and disturbed sleep and wakefulness
    Christian R Baumann
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    Neuromolecular Med 14:205-12. 2012
    ....
  3. ncbi request reprint [The neurotransmitter, hypocretin. An overview]
    C Baumann
    Neurologische Klinik, Universitatsspital Zurich
    Nervenarzt 75:317-23. 2004
    ..In most patients with other hypersomnolent syndromes or sleep-waking disturbances, hypocretin neurotransmission is normal. Other functions of the hypocretins include the regulation of food intake and of neuroendocrine mechanisms...
  4. pmc Loss of hypocretin (orexin) neurons with traumatic brain injury
    Christian R Baumann
    Department of Neurology, University Hospital, Zurich, Switzerland
    Ann Neurol 66:555-9. 2009
    ..This observation highlights the often overlooked hypothalamic injury in TBI and provides new insights into the causes of chronic sleepiness in patients with TBI...
  5. ncbi request reprint Lipoma on the corpus callosum in a patient with schizophrenia-like episode: is there a causal relationship?
    Christian R Baumann
    Department of Neurology, University Hospital, Zurich, Switzerland
    Cogn Behav Neurol 19:109-11. 2006
    ..We conclude that cerebral abnormality per se may represent a risk factor for neuropsychiatric symptoms...
  6. doi request reprint Epidemiology, diagnosis and differential diagnosis in Parkinson's disease tremor
    Christian R Baumann
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    Parkinsonism Relat Disord 18:S90-2. 2012
    ..In general, essential tremor and other tremor forms can be distinguished from Parkinson tremor by their frequency and their expression with different activation...
  7. doi request reprint Sleep-wake disturbances 3 years after traumatic brain injury
    Julia Kempf
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    J Neurol Neurosurg Psychiatry 81:1402-5. 2010
    ..The long-term course of post-traumatic SWD, however, is unknown...
  8. doi request reprint Sleep: approaching the fundamental questions
    Christian R Baumann
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    Curr Biol 18:R665-R667. 2008
    ..Our 'sleep need' may be defined as the daily amount of sleep we require to be fully awake during daytime. A recent study has shown that both sleep need and daytime sleepiness decline in older adults...
  9. doi request reprint Multiple sleep latency measures in narcolepsy and behaviourally induced insufficient sleep syndrome
    Isabelle Marti
    Department of Neurology, University Hospital of Zurich, Zurich, Switzerland
    Sleep Med 10:1146-50. 2009
    ..It is not known whether specific MSLT findings help differentiate the two disorders...
  10. doi request reprint Progressive dopamine and hypocretin deficiencies in Parkinson's disease: is there an impact on sleep and wakefulness?
    Miriam Wienecke
    Department of Neurology, University Hospital, Zurich, Switzerland
    J Sleep Res 21:710-7. 2012
    ..Despite hypocretin cell loss in Parkinson's disease being only partial, disturbed hypocretin signalling is likely to contribute to excessive daytime sleepiness in Parkinson patients...
  11. doi request reprint Increase of histaminergic tuberomammillary neurons in narcolepsy
    Philipp O Valko
    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA Department of Neurology, University Hospital of Zurich, Zurich, Switzerland
    Ann Neurol 74:794-804. 2013
    ..As cerebrospinal fluid histamine levels may be low in patients with narcolepsy, we examined histaminergic neurons in patients with narcolepsy and in 2 mouse models of narcolepsy...
  12. ncbi request reprint Excessive sleep need following traumatic brain injury: a case-control study of 36 patients
    Michael Sommerauer
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    J Sleep Res 22:634-9. 2013
    ..Furthermore, these patients exhibit an increase in slow-wave sleep which may reflect recovery mechanisms, intrinsic consequences of diffuse brain damage or relative sleep deprivation. ..
  13. doi request reprint Actigraphic assessment of periodic leg movements in patients with restless legs syndrome
    Maria A T Cippà
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    J Sleep Res 22:589-92. 2013
    ..Our retrospective study indicates that actigraphy to assess periodic limb movements may contribute to a better diagnosis of dopamine-responsive restless legs syndrome. ..
  14. ncbi request reprint Sleep-wake disturbances 6 months after traumatic brain injury: a prospective study
    Christian R Baumann
    Department of Neurology, University Hospital of Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    Brain 130:1873-83. 2007
    ..An involvement of the hypocretin system in the pathophysiology of post-traumatic SWD appears possible. Other risk factors predisposing towards the development of post-traumatic SWD were not identified...
  15. pmc Validation of the fatigue severity scale in a Swiss cohort
    Philipp O Valko
    Department of Neurology, University Hospital of Zurich, Zurich, Switzerland
    Sleep 31:1601-7. 2008
    ..The 9-item Fatigue Severity Scale (FSS) is one of the most commonly used self-report questionnaires to measure fatigue, but has only been validated in small sample-sized studies and in single disorders...
  16. doi request reprint Gamma-hydroxybutyrate accelerates functional recovery after focal cerebral ischemia
    Bo Gao
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    Cerebrovasc Dis 26:413-9. 2008
    ..This study aimed to assess recovery-promoting effects of GHB at a low dose similar to that used in patients...
  17. doi request reprint Stimulation sites in the subthalamic nucleus projected onto a mean 3-D atlas of the thalamus and basal ganglia
    Johannes Sarnthein
    Klinik für Neurochirurgie, Universitatsspital Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland
    Acta Neurochir (Wien) 155:1655-60. 2013
    ..It combines information contained in histological data from ten post-mortem brains. We were interested whether the Morel-Atlas is applicable for the visualization of stimulation sites...
  18. ncbi request reprint Sleepiness at the time of testing impairs olfactory performance
    Enea Ghielmini
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    Eur Neurol 69:58-64. 2013
    ..Olfaction in patients with Parkinson disease, restless leg syndrome, narcolepsy with cataplexy, EDS, and healthy controls was compared...
  19. ncbi request reprint Seizure outcome after resection of supratentorial cavernous malformations: a study of 168 patients
    Christian R Baumann
    Department of Neurology, University Hospital, Zurich, Switzerland
    Epilepsia 48:559-63. 2007
    ..The aim of our study was to examine seizure outcome in the largest published series of surgically treated patients with epilepsy due to a supratentorial CCM, and to define predictors for good surgical outcome...
  20. ncbi request reprint Hypocretins (orexins): clinical impact of the discovery of a neurotransmitter
    Christian R Baumann
    Neurologische Klinik, Universitatsspital Zurich, Frauenklinikstrasse 26, CH 8091 Zurich, Switzerland
    Sleep Med Rev 9:253-68. 2005
    ....
  21. ncbi request reprint Hypocretins (orexins) and sleep-wake disorders
    Christian R Baumann
    Department of Neurology, University Hospital, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    Lancet Neurol 4:673-82. 2005
    ..The exact function of the hypocretin system in sleep-wake regulation and its pathophysiological role in hypocretin-deficient and non-deficient narcolepsy as well as in non-narcoleptic, hypocretin-deficiency syndromes remain unclear...
  22. ncbi request reprint Sleep EEG changes after middle cerebral artery infarcts in mice: different effects of striatal and cortical lesions
    Christian R Baumann
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    Sleep 29:1339-44. 2006
    ..The correlation between these changes and stroke extent remains unclear. In the absence of experimental data, we assessed sleep EEG changes after focal cerebral ischemia of different extensions in mice...
  23. doi request reprint Sleep-disordered breathing and periodic limb movements in narcolepsy with cataplexy: a systematic analysis of 35 consecutive patients
    Fabio Pizza
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    Eur Neurol 70:22-6. 2013
    ..We systematically assessed both SDB and PLMs in well-defined NC patients...
  24. ncbi request reprint Revisiting the impact of REM sleep behavior disorder on motor progression in Parkinson's disease
    Michael Sommerauer
    Department of Neurology, Universitatsspital Zurich, Frauenklinikstrasse 26, CH 8091 Zurich, Switzerland Electronic address
    Parkinsonism Relat Disord 20:460-2. 2014
    ..However, their impact on motor progression remains elusive...
  25. pmc REM sleep behavior disorder in Parkinson's disease: a questionnaire-based survey
    Rositsa Poryazova
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    J Clin Sleep Med 9:55-9A. 2013
    ..Only a few systematic, large-scale studies have addressed the characteristics of RBD in PD. The aim of the present study is to assess the frequency of RBD in patients with PD and the association with PD characteristics...
  26. pmc Inter-hemispheric oscillations in human sleep
    Lukas L Imbach
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    PLoS ONE 7:e48660. 2012
    ..This quantitative approach provides a new way of examining the dynamic aspects of sleep, shedding new light on the physiology of human sleep...
  27. doi request reprint Heart rate variability in patients with idiopathic Parkinson's disease with and without obstructive sleep apnea syndrome
    Philipp O Valko
    Department of Neurology, University Hospital of Zurich, Switzerland
    Parkinsonism Relat Disord 18:525-31. 2012
    ..Sympathetic dysfunction evolves early in idiopathic Parkinson's disease (PD), but the consequences on cardiac autonomic response to OSAS have not been studied so far in PD patients...
  28. doi request reprint Body side and predominant motor features at the onset of Parkinson's disease are linked to motor and nonmotor progression
    Christian R Baumann
    Department of Neurology, University Hospital, Zurich, Switzerland
    Mov Disord 29:207-13. 2014
    ..Our findings corroborate that body side and type of motor signs at the time of diagnosis affect the evolution of motor severity and may also have an impact on some nonmotor manifestations...
  29. ncbi request reprint Time perception in narcolepsy in comparison to patients with Parkinson's disease and healthy controls - an exploratory study
    Rositsa Poryazova
    University Hospital Zurich, Zurich, Switzerland
    J Sleep Res 22:625-33. 2013
    ..The time-course of accuracy and variability of time production within sessions indicate an attention-related mechanism of impaired interval timing. ..
  30. pmc Observations on sleep-disordered breathing in idiopathic Parkinson's disease
    Philipp O Valko
    Department of Neurology, University Hospital of Zurich, Zurich, Switzerland
    PLoS ONE 9:e100828. 2014
    ..to determine the potential influence of dopaminergic drugs on sleep-disordered breathing (SDB) in Parkinson's disease (PD) and 2.) to elucidate whether NREM and REM sleep differentially impact SDB severity in PD...
  31. doi request reprint Subthalamic deep brain stimulation versus best medical therapy for L-dopa responsive pain in Parkinson's disease
    Oguzkan Sürücü
    Department of Neurosurgery, University Hospital Zurich, Switzerland
    Pain 154:1477-9. 2013
    ..This diagnostic procedure could contribute to the decision on whether or not a Parkinson's patient with severe pain should undergo deep brain stimulation for potential pain relief...
  32. ncbi request reprint Serum cholesterol levels do not influence outcome or recovery in acute ischemic stroke
    Hans Christian von Büdingen
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    Neurol Res 30:82-4. 2008
    ..To examine the influence of admission serum cholesterol levels (SCL) on severity of initial neurological deficit, neurological outcome at month 3 and neurological recovery in patients with acute first-ever ischemic stroke...
  33. doi request reprint No persistent effect of intravenous immunoglobulins in patients with narcolepsy with cataplexy
    Philipp O Valko
    Department of Neurology, University Hospital of Zurich, Frauenklinikstrasse 26, Zurich, Switzerland
    J Neurol 255:1900-3. 2008
    ..Our report challenges the recent observations of a favorable and persistent effect of IVIg in NC patients...
  34. pmc Challenges in diagnosing narcolepsy without cataplexy: a consensus statement
    Christian R Baumann
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
    Sleep 37:1035-42. 2014
    ....
  35. doi request reprint Sleepwalking, REM sleep behaviour disorder and overlap parasomnia in patients with Parkinson's disease
    Nadia Di Fabio
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    Eur Neurol 70:297-303. 2013
    ..We aimed to assess the clinical and polysomnographic characteristics of SW in PD and to compare them to patients with PD with and without a history of RBD...
  36. ncbi request reprint CSF prostaglandin D synthase is reduced in excessive daytime sleepiness
    Claudio L Bassetti
    Department of Neurology, Universitatsspital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    J Neurol 253:1030-3. 2006
    ..Thus, L-PGDS may represent the first neurochemical measure of excessive daytime sleepiness...
  37. ncbi request reprint Gustav Flaubert's "nervous disease": an autobiographic and epileptological approach
    Luzia M Arnold
    Department of Neurology, University Hospital, Frauenklinikstrasse 26, CH 8091, Zurich, Switzerland
    Epilepsy Behav 11:212-7. 2007
    ..In our opinion, psychopathological considerations suggest primary involvement of mesial temporal lobe structures with typical findings of ictal and interictal mood behavior...
  38. ncbi request reprint Seizure outcome after resection of cavernous malformations is better when surrounding hemosiderin-stained brain also is removed
    Christian R Baumann
    Department of Neurology, University Hospital, Zurich, Switzerland
    Epilepsia 47:563-6. 2006
    ..The purpose of this study was to test the hypothesis whether seizure outcome after removal of cavernous malformations may be related to the extent of resection of surrounding hemosiderin-stained brain tissue...
  39. pmc Development of a short sleeper phenotype after third ventriculostomy in a patient with ependymal cysts
    Katharina Seystahl
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    J Clin Sleep Med 10:211-3. 2014
    ..This might suggest that individual short sleep need is not only determined by genetics but can be also be induced by external factors...
  40. ncbi request reprint Did Fyodor Mikhailovich Dostoevsky suffer from mesial temporal lobe epilepsy?
    Christian R Baumann
    Department of Neurology, University Hospital, Frauenklinikstrasse 26, CH 8091 Zurich, Switzerland
    Seizure 14:324-30. 2005
    ..Moreover, we attempt to classify Dostoevsky's epilepsy on the basis of his bibliography, language, and literary work...
  41. ncbi request reprint Amyotrophic lateral sclerosis after embolization of cerebral arterioveneous malformations
    Anton Valavanis
    Institute of Neuroradiology, University Hospital Zurich, Frauenklinikstrasse 10, CH, 8091, Zurich, Switzerland
    J Neurol 261:732-7. 2014
    ..ALS should be considered as a late complication of multiple embolizations of cerebral AVM characterized by significant perinidal angiogenesis...
  42. doi request reprint Sleep benefit in Parkinson's disease is associated with short sleep times
    Eskender Sherif
    Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    Parkinsonism Relat Disord 20:116-8. 2014
    ..The link between the occurrence of sleep benefit and shorter nocturnal sleep in Parkinson's disease remains unclear. ..
  43. doi request reprint Cortical morphometry in narcolepsy with cataplexy
    Marie Schaer
    Office Médico Pédagogique, Department of Psychiatry, Geneva Faculty of Medicine, Geneva, Switzerland
    J Sleep Res 21:487-94. 2012
    ..Future studies with larger groups of sleepy patients are required to assess whether distinct patterns of anatomical changes may distinguish narcolepsy from non-hypocretin-deficient hypersomnia disorders...
  44. ncbi request reprint Good outcomes in ischemic stroke patients treated with intravenous thrombolysis despite regressing neurological symptoms
    Christian R Baumann
    Department of Neurology, University of Zurich, Zurich, Switzerland
    Stroke 37:1332-3. 2006
    ..We evaluated the clinical course of 19 acute stroke patients with rapid early improvement of neurological deficit within the 3-hour window, treated with intravenous thrombolytics...
  45. ncbi request reprint Parkinson's disease, sleepiness and hypocretin/orexin
    Christian R Baumann
    Brain 131:e91. 2008
  46. pmc Do enteric neurons make hypocretin?
    Christian R Baumann
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Institutes of Medicine, Boston, USA
    Regul Pept 147:1-3. 2008
    ..These results raise doubts about whether enteric neurons produce hypocretin...
  47. ncbi request reprint CSF hypocretin levels in Guillain-Barré syndrome and other inflammatory neuropathies
    Christian R Baumann
    Neurology 62:2337; author reply 2337. 2004
  48. ncbi request reprint Hypocretin-1 (orexin A) levels are normal in Huntington's disease
    Christian R Baumann
    J Neurol 253:1232-3. 2006