Research Topics
Species | Sylvette BasSummaryAffiliation: University Hospital Country: Switzerland Publications
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Publications
In infertile women, cells from Chlamydia trachomatis infected sites release higher levels of interferon-gamma, interleukin-10 and tumor necrosis factor-alpha upon heat-shock-protein stimulation than fertile womenPragya Srivastava
Institute of Pathology ICMR, Safdarjung Hospital Campus, Post Box no, 4909, New Delhi 110 029, India
Reprod Biol Endocrinol 6:20. 2008..Hence study of specific cytokine responses of mononuclear cells from the infectious site to cHSP60 and cHSP10 may elucidate their actual role in the cause of immunopathogenesis and the disease outcome...
Diagnostic value of anti-cyclic citrullinated peptides and association with HLA-DRB1 shared epitope alleles in African rheumatoid arthritis patientsMadeleine Singwe-Ngandeu
Unit of Rheumatology, Department of Internal Medicine, School of Medicine, University of Yaounde, Yaounde, Cameroon
Arthritis Res Ther 12:R36. 2010....
CD14 is an acute-phase proteinSylvette Bas
Division of Rheumatology, Department of Internal Medicine, University Hospital, Geneva, Switzerland
J Immunol 172:4470-9. 2004..Liver levels of CD14 mRNA increased in IL-6(+/+), but not in IL-6(-/-) mice. These results indicate that sCD14 can be considered as a type 2 APP...
Anti-cyclic citrullinated peptide antibodies, IgM and IgA rheumatoid factors in the diagnosis and prognosis of rheumatoid arthritisS Bas
Division of Rheumatology, Department of Internal Medicine, University Hospital, Geneva, Switzerland
Rheumatology (Oxford) 42:677-80. 2003....
[Usefulness of anti-citrullinated protein antibodies in the diagnosis and prognosis of rheumatoid arthritis]S Bas
Service de Rhumatologie, Departement de Medecine Interne, HUG Hôpital Beau Séjour 1211 Genève 14
Rev Med Suisse 1:674, 677-8, 680 passim. 2005..Consequently, incorporation of anti-citrullinated protein antibody positivity as an extra criteria would improve the accuracy of the American College of Rheumatology criteria, commonly used for disease classification...
Comparative study of different enzyme immunoassays for measurement of IgM and IgA rheumatoid factorsS Bas
Division of Rheumatology, Department of Internal Medicine, University Hospital, Geneva, Switzerland
Ann Rheum Dis 61:505-10. 2002..To compare the value of various IgM and IgA rheumatoid factor (RF) tests for the diagnosis of rheumatoid arthritis (RA)...
The proinflammatory cytokine response to Chlamydia trachomatis elementary bodies in human macrophages is partly mediated by a lipoprotein, the macrophage infectivity potentiator, through TLR2/TLR1/TLR6 and CD14Sylvette Bas
Division of Rheumatology, Department of Internal Medicine, University Hospital, and Department of Pathology and Immunology, Geneva Medical School, Switzerland
J Immunol 180:1158-68. 2008..Stimulating pathways appeared to involve TLR2/TLR1/TLR6 with the help of CD14 but not TLR4. These data support a role of Mip lipoprotein in pathogenesis of C. trachomatis-induced inflammatory responses...
Serum lipoproteins attenuate macrophage activation and Toll-Like Receptor stimulation by bacterial lipoproteinsSylvette Bas
Division of Rheumatology, Department of Internal Medicine, Geneva University Hospital, 1211 Geneva 14, Switzerland
BMC Immunol 11:46. 2010..Finally, TLR1/2 human embryonic kidney-293 (HEK-293) transfected cells were used to test the ability of the serum factors to inhibit Mip and OspA proinflammatory activity...
Lower level of synovial fluid interferon-gamma in HLA-B27-positive than in HLA-B27-negative patients with Chlamydia trachomatis reactive arthritisS Bas
Division of Rheumatology, Department of Internal Medicine, University Hospital, Geneva, Switzerland
Rheumatology (Oxford) 42:461-7. 2003....
Evaluation of cardiovascular risk in patients with rheumatoid arthritis: do cardiovascular biomarkers offer added predictive ability over established clinical risk scores?Axel Finckh
Geneva University Hospitals and University of Geneva School of Medicine, 26 Avenue Beau Sejour, Geneva, Switzerland
Arthritis Care Res (Hoboken) 64:817-25. 2012....
Anti-apolipoprotein A-1 IgG predicts major cardiovascular events in patients with rheumatoid arthritisNicolas Vuilleumier
Geneva University Hospitals, Geneva, Switzerland
Arthritis Rheum 62:2640-50. 2010..To determine whether anti-apolipoprotein A-1 (anti-Apo A-1) IgG are associated with major cardiovascular events in patients with rheumatoid arthritis (RA)...
Importance of species-specific antigens in the serodiagnosis of Chlamydia trachomatis reactive arthritisS Bas
Division of Rheumatology, Department of Internal Medicine, University Hospital, Geneva, Switzerland
Rheumatology (Oxford) 41:1017-20. 2002..CONCLUSIONS: IgG and/or IgA anti-MOMP-derived peptides and anti-pgp3 could be useful for the diagnosis of probable C. trachomatis reactive arthritis...
Indirect evidence of intra-articular immunoglobulin G synthesis in patients with Chlamydia trachomatis reactive arthritisS Bas
Division of Rheumatology, Department of Internal Medicine, University Hospital, Geneva, Switzerland
Rheumatology (Oxford) 40:801-5. 2001..CONCLUSIONS: These results suggest an intra-articular IgG production and a possible role of some Chlamydia antigens like OMP2 in the pathogenesis of C. trachomatis reactive arthritis...
Molecular characterization and subcellular localization of macrophage infectivity potentiator, a Chlamydia trachomatis lipoproteinLaurence Neff
Division of Rheumatology, Department of Internal Medicine, University Hospital, 1211 Geneva 14, Switzerland
J Bacteriol 189:4739-48. 2007....
Distinct serum and synovial fluid interleukin (IL)-33 levels in rheumatoid arthritis, psoriatic arthritis and osteoarthritisDominique Talabot-Ayer
Division of Rheumatology, University Hospital, Geneva, Switzerland
Joint Bone Spine 79:32-7. 2012....
Diagnostic tests for rheumatoid arthritis: comparison of anti-cyclic citrullinated peptide antibodies, anti-keratin antibodies and IgM rheumatoid factorsS Bas
Division of Rheumatology, Department of Internal Medicine, University Hospital, Geneva, Switzerland
Rheumatology (Oxford) 41:809-14. 2002..CONCLUSIONS: With their excellent specificity, anti-CCP antibodies can be useful in establishing the diagnosis of RA, but IgM RF is a better predictor of disease severity...
Influence of anti-infliximab antibodies and residual infliximab concentrations on the occurrence of acquired drug resistance to infliximab in rheumatoid arthritis patientsAxel Finckh
Division of Rheumatology, Department of Internal Medicine, University Hospital of Geneva, 26, Avenue Beau Sejour, 1211 Geneva, Switzerland
Joint Bone Spine 77:313-8. 2010..Infliximab (IFX) can be immunogenic for humans and lead to the formation of antibodies against IFX (anti-IFX Ab), which could induce acquired IFX resistance...
Chlamydial serology: comparative diagnostic value of immunoblotting, microimmunofluorescence test, and immunoassays using different recombinant proteins as antigensS Bas
Division of Rheumatology, University Hospital, 1211 Geneva 14, Switzerland
J Clin Microbiol 39:1368-77. 2001..trachomatis antigens, which were 76 and 77%, respectively, when IgG responses to both recombinant hsp60 and pgp3 were considered...
Male sex predominance in Chlamydia trachomatis sexually acquired reactive arthritis: are women more protected by anti-chlamydia antibodies?S Bas
Division of Rheumatology, Department of Internal Medicine, University Hospital, Geneva, Switzerland
Ann Rheum Dis 60:605-11. 2001....
Relation between the heavy chain complementarity region 3 characteristics and rheumatoid factor binding propertiesS Bas
Department of Medicine, University Hospital, Geneva, Switzerland
Autoimmunity 27:191-9. 1998....
Chlamydia trachomatis serology: diagnostic value of outer membrane protein 2 compared with that of other antigensS Bas
Division of Rheumatology, Department of Internal Medicine, University Hospital, Switzerland
J Clin Microbiol 39:4082-5. 2001..The highest sensitivity (89%) was obtained with anti-OMP2 IgG, but the lowest specificity (57%) was obtained with this antibody, due to probable cross-reactivity with C. pneumoniae OMP2...
The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytesDavid Magne
Division of Rheumatology, Department of Internal Medicine, University Hospital and Department of Pathology and Immunology, University of Geneva School of Medicine, Geneva, Switzerland
Arthritis Res Ther 8:R80. 2006..It remains to be determined whether circulating IL-1F8 can contribute to joint inflammation in rheumatoid arthritis...
False positive elevation of cardiac troponin I in seropositive rheumatoid arthritisSylvette Bas
J Rheumatol 29:2665. 2002
