Matthias Barton

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi request reprint Endothelin, hypercholesterolemia and atherosclerosis
    Matthias Barton
    Medical Policlinic, Department of Internal Medicine, University Hospital, Zurich, Switzerland
    Coron Artery Dis 14:477-90. 2003
  2. doi request reprint Endothelin: 20 years from discovery to therapy
    Matthias Barton
    Klinik und Poliklinik für Innere Medizin, Departement fur Innere Medizin, Universitatsspital Zurich, Zurich, Switzerland
    Can J Physiol Pharmacol 86:485-98. 2008
  3. doi request reprint Reversal of proteinuric renal disease and the emerging role of endothelin
    Matthias Barton
    Department of Internal Medicine, Klinik und Poliklinik für Innere Medizin, Universitatsspital Zurich, Zurich, Switzerland
    Nat Clin Pract Nephrol 4:490-501. 2008
  4. ncbi request reprint Fat intake modifies vascular responsiveness and receptor expression of vasoconstrictors: implications for diet-induced obesity
    Alexa L Mundy
    Department of Medicine, Internal Medicine I, Medical Policlinic, University Hospital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Cardiovasc Res 73:368-75. 2007
  5. ncbi request reprint Impaired vascular function in normoglycemic mice prone to autoimmune diabetes: role of nitric oxide
    Tobias Traupe
    Department of Medicine, Internal Medicine I, Medical Policlinic, University Hospital Zurich, Switzerland
    Eur J Pharmacol 557:161-7. 2007
  6. doi request reprint Regional heterogeneity of functional changes in conduit arteries after high-fat diet
    Indranil Bhattacharya
    Department of Medicine, Internal Medicine I, Medical Policlinic, University Hospital, Zurich, Switzerland
    Obesity (Silver Spring) 16:743-8. 2008
  7. ncbi request reprint Upregulation of endothelin converting enzyme-1 in host liver during chronic cardiac allograft rejection
    Thomas Lattmann
    Medical Policlinic, Department of Medicine, University Hospital, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Exp Biol Med (Maywood) 231:899-901. 2006
  8. ncbi request reprint Antioxidant activity and sex differences of acute vascular effects of amiodarone in advanced atherosclerosis
    Tobias Traupe
    Department of Internal Medicine, Internal Medicine I, Medical Policlinic, University Hospital Zurich, Zurich, Switzerland
    J Cardiovasc Pharmacol 50:578-84. 2007
  9. ncbi request reprint Differential effects of 17beta-estradiol on function and expression of estrogen receptor alpha, estrogen receptor beta, and GPR30 in arteries and veins of patients with atherosclerosis
    Elvira Haas
    Department of Internal Medicine, Internal Medicine I, Medical Policlinic, Zurich, Switzerland
    Hypertension 49:1358-63. 2007
  10. ncbi request reprint Endothelin ETA receptor blockade with darusentan increases sodium and potassium excretion in aging rats
    Tobias Traupe
    Departement fur Innere Medizin, Medizinische Poliklinik, Universitatsspital, Zurich, Switzerland
    J Cardiovasc Pharmacol 47:456-62. 2006

Collaborators

Detail Information

Publications59

  1. ncbi request reprint Endothelin, hypercholesterolemia and atherosclerosis
    Matthias Barton
    Medical Policlinic, Department of Internal Medicine, University Hospital, Zurich, Switzerland
    Coron Artery Dis 14:477-90. 2003
  2. doi request reprint Endothelin: 20 years from discovery to therapy
    Matthias Barton
    Klinik und Poliklinik für Innere Medizin, Departement fur Innere Medizin, Universitatsspital Zurich, Zurich, Switzerland
    Can J Physiol Pharmacol 86:485-98. 2008
    ..Possible future indications include resistant arterial hypertension, proteinuric renal disease, cancer, and connective tissue diseases...
  3. doi request reprint Reversal of proteinuric renal disease and the emerging role of endothelin
    Matthias Barton
    Department of Internal Medicine, Klinik und Poliklinik für Innere Medizin, Universitatsspital Zurich, Zurich, Switzerland
    Nat Clin Pract Nephrol 4:490-501. 2008
    ..Additional clinical studies are needed...
  4. ncbi request reprint Fat intake modifies vascular responsiveness and receptor expression of vasoconstrictors: implications for diet-induced obesity
    Alexa L Mundy
    Department of Medicine, Internal Medicine I, Medical Policlinic, University Hospital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Cardiovasc Res 73:368-75. 2007
    ..The aim of this study was to investigate the effects of dietary fat content on vasoreactivity and receptor expression at the level of gene and protein expression...
  5. ncbi request reprint Impaired vascular function in normoglycemic mice prone to autoimmune diabetes: role of nitric oxide
    Tobias Traupe
    Department of Medicine, Internal Medicine I, Medical Policlinic, University Hospital Zurich, Switzerland
    Eur J Pharmacol 557:161-7. 2007
    ..Early proinflammatory activation due to iNOS in diabetes-prone NOD mice appears to be one of the mechanisms contributing to impaired vasoreactivity...
  6. doi request reprint Regional heterogeneity of functional changes in conduit arteries after high-fat diet
    Indranil Bhattacharya
    Department of Medicine, Internal Medicine I, Medical Policlinic, University Hospital, Zurich, Switzerland
    Obesity (Silver Spring) 16:743-8. 2008
    ..To determine effects of dietary fat content on vascular responses in different conduit arteries in mice...
  7. ncbi request reprint Upregulation of endothelin converting enzyme-1 in host liver during chronic cardiac allograft rejection
    Thomas Lattmann
    Medical Policlinic, Department of Medicine, University Hospital, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Exp Biol Med (Maywood) 231:899-901. 2006
    ..Because the liver represents both a key organ for cytokine production and for endothelin metabolism, increased hepatic ECE-1-mediated ET-1 synthesis may contribute to host responses and cytokine production during allograft rejection...
  8. ncbi request reprint Antioxidant activity and sex differences of acute vascular effects of amiodarone in advanced atherosclerosis
    Tobias Traupe
    Department of Internal Medicine, Internal Medicine I, Medical Policlinic, University Hospital Zurich, Zurich, Switzerland
    J Cardiovasc Pharmacol 50:578-84. 2007
    ..Antioxidant and vasodilator effects following amiodarone administration may contribute to its antiarrhythmic effects...
  9. ncbi request reprint Differential effects of 17beta-estradiol on function and expression of estrogen receptor alpha, estrogen receptor beta, and GPR30 in arteries and veins of patients with atherosclerosis
    Elvira Haas
    Department of Internal Medicine, Internal Medicine I, Medical Policlinic, Zurich, Switzerland
    Hypertension 49:1358-63. 2007
    ..These data indicate that effects of natural estrogens in humans differ between arterial and venous vascular beds, which may contribute to the vascular risks associated with menopause or hormone therapy...
  10. ncbi request reprint Endothelin ETA receptor blockade with darusentan increases sodium and potassium excretion in aging rats
    Tobias Traupe
    Departement fur Innere Medizin, Medizinische Poliklinik, Universitatsspital, Zurich, Switzerland
    J Cardiovasc Pharmacol 47:456-62. 2006
    ..These findings may provide new pathogenetic links between aging and sodium sensitivity...
  11. ncbi request reprint Downregulation of renal endothelin-converting enzyme 2 expression in early autoimmune diabetes
    Jana Ortmann
    Medical Policlinic, Department of Internal Medicine, University Hospital Zurich, Switzerland
    Exp Biol Med (Maywood) 231:1030-3. 2006
    ..Blockade of ET(A) receptors inhibits diabetes-associated gene regulation and delays the onset of diabetes, suggesting its therapeutic potential for the treatment of autoimmune forms of diabetes...
  12. ncbi request reprint Anatomically distinct activation of endothelin-3 and the L-arginine/nitric oxide pathway in the kidney with advanced aging
    Thomas Lattmann
    Medical Policlinic, Department of Medicine, University Hospital, Zurich, Switzerland
    Biochem Biophys Res Commun 327:234-41. 2005
    ..These findings could be important for pathologies and possibly therapy associated with renal aging...
  13. ncbi request reprint Transcriptional regulation of vascular bone morphogenetic protein by endothelin receptors in early autoimmune diabetes mellitus
    Philipp C Nett
    Medical Policlinic, University Hospital of Zurich, Switzerland
    Life Sci 78:2213-8. 2006
    ....
  14. ncbi request reprint Endothelin stimulates vascular hydroxyl radical formation: effect of obesity
    Alexa L Mundy
    Molecular Internal Medicine, Medical Policlinic, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland
    Am J Physiol Regul Integr Comp Physiol 293:R2218-24. 2007
    ....
  15. ncbi request reprint Role of podocytes for reversal of glomerulosclerosis and proteinuria in the aging kidney after endothelin inhibition
    Jana Ortmann
    Medizinische Poliklinik, Universitatsspital Zurich, Switzerland
    Hypertension 44:974-81. 2004
    ..The results further suggest that age-dependent glomerulosclerosis is not merely a "degenerative" but a reversible process locally confined to the glomerulus involving recovery of podocytes from previous injury...
  16. ncbi request reprint Activation of pro-inflammatory and anti-inflammatory cytokines in host organs during chronic allograft rejection: role of endothelin receptor signaling
    Thomas Lattmann
    Medical Policlinic, Department of Medicine, University Hospital, Zurich, Switzerland
    Am J Transplant 5:1042-9. 2005
    ..These data provide evidence for distinct pro-inflammatory local activation in host organs during chronic rejection and suggest a role for ET(A) receptors contributing to regulation of cytokine plasma levels and transcriptional activity...
  17. pmc Dilation of epicardial coronary arteries by the G protein-coupled estrogen receptor agonists G-1 and ICI 182,780
    Matthias R Meyer
    Molecular Internal Medicine, University of Zurich, Zurich, Switzerland
    Pharmacology 86:58-64. 2010
    ..s.). In summary, these findings provide evidence for direct and indirect coronary artery dilator effects of GPER independent of ERalpha and ERbeta, and are the first demonstration of arterial vasodilation in response to ICI 182,780...
  18. pmc Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity
    Elvira Haas
    Departement fur Innere Medizin, Klinik und Poliklinik für Innere Medizin, Universitatsspital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Circ Res 104:288-91. 2009
    ..Deletion of the GPER gene in mice abrogates vascular effects of GPER activation and is associated with visceral obesity. These findings suggest novel roles for GPER in protecting from cardiovascular disease and obesity...
  19. ncbi request reprint Amiodarone acutely inhibits vascular activity of endothelin-converting enzymes
    Tobias Traupe
    Medizinishe Poliklinik and Departement für Innere Medizin, Universitatsspital Zurich, Zurich, Switzerland
    J Cardiovasc Pharmacol 44:S113-6. 2004
    ..Acute effects of amiodarone on endothelin-converting enzymes may contribute to its antiarrhythmic properties...
  20. ncbi request reprint Upregulation of vascular ET(B) receptor gene expression after chronic ET(A) receptor blockade in prediabetic NOD mice
    Jana Ortmann
    Medical Policlinic, University Hospital Zurich, Zurich, Switzerland
    J Cardiovasc Pharmacol 44:S105-8. 2004
    ..Furthermore, ETA receptor blockade is effective in increasing ETB receptor gene expression, suggesting a potential role for endothelin ETA antagonists in the treatment of type 1 diabetes...
  21. ncbi request reprint Early aging and anatomic heterogeneity determine cyclooxygenase-mediated vasoconstriction to angiotensin II in mice
    Martin Kretz
    Department of Medicine, Internal Medicine I, Medical Policlinic, University Hospital, Zurich, Switzerland
    J Cardiovasc Pharmacol 48:30-3. 2006
    ..AngII-induced vasoconstriction in vessels more distal to the heart such as femoral and renal arteries is only in part mediated by COX-dependent mechanisms that remain unaffected by early aging...
  22. ncbi request reprint Fat intake and cardiovascular response
    Marlen Damjanovic
    Klinik und Poliklinik für Innere Medizin, Departement fur Innere Medizin, Universitatsspital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
    Curr Hypertens Rep 10:25-31. 2008
    ..The beneficial effects of vasoactive mediators on vascular function could play a role for susceptibility to obesity-dependent hypertension, which is present in many, but not all, obese patients...
  23. ncbi request reprint Endothelin inhibition delays onset of hyperglycemia and associated vascular injury in type I diabetes: evidence for endothelin release by pancreatic islet beta-cells
    Jana Ortmann
    Medical Policlinic, University Hospital Zurich, Switzerland
    Biochem Biophys Res Commun 334:689-95. 2005
    ..These data suggest a critical role for ET(A) receptor signaling in the development of autoimmune forms of diabetes and the early vascular injury associated with it...
  24. pmc Non-genomic regulation of vascular cell function and growth by estrogen
    Matthias R Meyer
    Departement fur Innere Medizin, Klinik und Poliklinik für Innere Medizin, Universitatsspital, Zurich, Switzerland
    Mol Cell Endocrinol 308:9-16. 2009
    ..This review discusses recent advances in understanding of the mechanisms of non-genomic estrogen receptor signaling in the vascular wall...
  25. doi request reprint Obesity and aging: determinants of endothelial cell dysfunction and atherosclerosis
    Matthias Barton
    Molecular Internal Medicine, University of Zurich, LTK Y44 G22, Winterthurerstrasse 190, CH 8057, Zurich, Switzerland
    Pflugers Arch 460:825-37. 2010
    ..Pathomechanisms as well as the clinical issues of obesity- and aging-associated vascular changes important for atherosclerosis development and prevention are discussed...
  26. ncbi request reprint Obesity-associated activation of angiotensin and endothelin in the cardiovascular system
    Matthias Barton
    Medical Policlinic, Department of Internal Medicine, University Hospital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Int J Biochem Cell Biol 35:826-37. 2003
    ....
  27. ncbi request reprint Beneficial cardiovascular effects of endothelin ET(A) receptor blockade in established long-term heart failure after myocardial infarction
    Diana Vetter
    Medizinische Poliklinik, Universitatsspital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Exp Biol Med (Maywood) 231:857-60. 2006
    ..The changes observed occurred independently of tissue ET-1 concentrations and heart rate, suggesting mechanisms independent of local cardiac or pulmonary ET-1 synthesis, which are yet to be identified...
  28. doi request reprint Endothelin antagonism and reversal of proteinuric renal disease in humans
    Matthias Barton
    Molecular Internal Medicine, University of Zurich, Zurich, Switzerland
    Contrib Nephrol 172:210-22. 2011
    ..This article will discuss the underlying mechanisms of the antiproteinuric effects of ET antagonists, and summarize recent clinical trials in the field and the therapeutic potential of the ERA class of drugs for renal medicine...
  29. pmc Obesity and risk of vascular disease: importance of endothelium-dependent vasoconstriction
    Matthias Barton
    Molecular Internal Medicine, University of Zurich, Zurich, Switzerland
    Br J Pharmacol 165:591-602. 2012
    ..LINKED ARTICLES: This article is part of a themed section on Fat and Vascular Responsiveness. To view the other articles in this section visit http://dx.doi.org/10.1111/bph.2012.165.issue-3...
  30. ncbi request reprint Obesity increases prostanoid-mediated vasoconstriction and vascular thromboxane receptor gene expression
    Tobias Traupe
    Medical Policlinic and Clinical Atherosclerosis Research Laboratory, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland
    J Hypertens 20:2239-45. 2002
    ..Vasoconstrictor prostanoids have been implicated in abnormal vasomotion in atherosclerosis and hypertension...
  31. doi request reprint Need for research on estrogen receptor function: importance for postmenopausal hormone therapy and atherosclerosis
    Matthias R Meyer
    Departement fur Innere Medizin, Molekulare Innere Medizin, Klinik und Poliklinik für Innere Medizin, Universitatsspital, Zurich, Switzerland
    Gend Med 5:S19-33. 2008
    ..Although rare in premenopausal women, its incidence rises sharply after menopause, indicating atheroprotective effects of endogenous estrogens...
  32. ncbi request reprint Acute effects of 17 beta-oestradiol on functional activity of endothelin-converting enzymes in human arteries and veins
    Andres Heigl
    Medical Policlinic and Clinical Atherosclerosis Research Laboratory, Medical Policlinic, Department of Internal Medicine, University Hospital, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Clin Sci (Lond) 103:438S-441S. 2002
    ..Whether changes in FEA play a role in the vascular effects of 17 beta-oestradiol in vivo remains to be determined...
  33. ncbi request reprint Endothelial therapy of atherosclerosis and its risk factors
    Tobias Traupe
    Medical Policlinic, Department of Medicine, University Hospital Zurich, Switzerland
    Curr Vasc Pharmacol 1:111-21. 2003
    ..These treatments also have therapeutic benefit for patients at risk or with overt atherosclerosis, to reduce vascular and myocardial complications of this disease...
  34. ncbi request reprint Rapid endocytosis of copper-zinc superoxide dismutase into human endothelial cells: role for its vascular activity
    Ernst R Waelti
    Department of Medicine, Internal Medicine I, Medical Policlinic, University Hospital Zurich, Zurich, Switzerland
    Pharmacology 78:198-201. 2006
    ..Intracellular uptake via endocytosis may contribute to the vascular effects of CuZn-SOD, including vasodilation, and is likely to play a role in regulation of vascular tone and diseases such as atherosclerosis...
  35. ncbi request reprint Vascular consequences of menopause and hormone therapy: importance of timing of treatment and type of estrogen
    Raghvendra K Dubey
    Center for Clinical Pharmacology, University of Pittsburgh, Pittsburgh, PA, USA
    Cardiovasc Res 66:295-306. 2005
    ....
  36. ncbi request reprint Recent developments on endothelin antagonists as immunomodulatory drugs--from infection to transplantation medicine
    Philipp C Nett
    Department of Medicine, Internal Medical I, Medical Policlinic, University Hospital Zurich, Ramistrasse 100, Zurich, Switzerland
    Recent Pat Cardiovasc Drug Discov 1:265-76. 2006
    ....
  37. pmc The G protein-coupled estrogen receptor GPER/GPR30 as a regulator of cardiovascular function
    Matthias R Meyer
    Molecular Internal Medicine, University of Zurich, Zurich, Switzerland
    Vascul Pharmacol 55:17-25. 2011
    ....
  38. ncbi request reprint Marked heterogeneity of endothelin-mediated contractility and contraction dynamics in mouse renal and femoral arteries
    Corinne C Widmer
    Medical Policlinic, University Hospital Zurich, Switzerland
    Exp Biol Med (Maywood) 231:777-81. 2006
    ..These findings may be important for studying the effects of endothelin in mouse models of human disease...
  39. pmc Alike but not the same: anatomic heterogeneity of estrogen receptor-mediated vasodilation
    Matthias Barton
    Molecular Internal Medicine, University of Zurich, Zurich, Switzerland
    J Cardiovasc Pharmacol 62:22-5. 2013
    ....
  40. doi request reprint Childhood obesity: a life-long health risk
    Matthias Barton
    Molecular Internal Medicine, University of Zurich, Winterthurerstrasse 190, Zurich, Switzerland
    Acta Pharmacol Sin 33:189-93. 2012
    ..The importance of childhood obesity for disease susceptibility later in life, and the need for prevention and treatment are also discussed...
  41. doi request reprint Endothelin antagonists in clinical trials: lessons learned
    Matthias Barton
    Molecular Internal Medicine, University of Zurich, Zurich, Switzerland
    Contrib Nephrol 172:255-60. 2011
    ..The reasons for the failure of some of these studies and general considerations about how to move forward with clinical studies involving ERAs in renal disease are discussed in this chapter...
  42. ncbi request reprint Oral contraceptives and the risk of thrombosis and atherosclerosis
    Matthias Barton
    Department of Internal Medicine, Medical Policlinic, and Clinical Atherosclerosis Laboratory, University Hospital Zurich, Ramistrasse 100, CH 8091 Zürich Switzerland
    Expert Opin Investig Drugs 11:329-32. 2002
    ..This article discusses mechanistic and clinical issues and reviews the need for novel approaches targeting the considerable side effects in order to reduce cardiovascular morbidity in women using oral contraceptives...
  43. ncbi request reprint Lovastatin stimulates human vascular smooth muscle cell expression of bone morphogenetic protein-2, a potent inhibitor of low-density lipoprotein-stimulated cell growth
    Luca Emmanuele
    Department of Internal Medicine, Medical Policlinic, University Hospital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Biochem Biophys Res Commun 302:67-72. 2003
    ..05). Induction of BMPs and subsequent inhibition of VSMC growth and/or induction of vascular bone formation could contribute to the mechanisms by which statins increase plaque stability in patients with coronary atherosclerosis...
  44. ncbi request reprint Gender differences of cardiovascular disease: new perspectives for estrogen receptor signaling
    Matthias R Meyer
    Department of Internal Medicine, Medical Policlinic, University Hospital Zurich, Switzerland
    Hypertension 47:1019-26. 2006
  45. ncbi request reprint Increased expression of endothelin-converting enzyme-1 in failing human myocardium
    Henning Morawietz
    Institute of Pathophysiology, Faculty of Medicine, Martin Luther University Halle Wittenberg, Magdeburger Strasse 18, D 06097 Halle, Germany
    Clin Sci (Lond) 103:237S-240S. 2002
    ..Pharmacological inhibition of augmented ECE-1 expression might provide a new therapeutic perspective in the treatment of heart failure...
  46. ncbi request reprint Effects of obesity on endothelium-dependent reactivity during acute nitric oxide synthase inhibition: modulatory role of endothelin
    Tobias Traupe
    Department of Internal Medicine and Medical Policlinic, University Hospital Zurich, CH 8091 Zurich, Switzerland
    Clin Sci (Lond) 103:13S-15S. 2002
    ..This effect can be completely prevented by chronic ET(A) receptor blockade, suggesting that endothelin modulates increased endothelium-dependent vasoconstriction in obesity...
  47. ncbi request reprint Inflammation and atherosclerosis
    Matthias Barton
    Circ Res 101:750-1. 2007
  48. ncbi request reprint Upregulation of endothelin receptor B in human endothelial cells by low-density lipoproteins
    Gregor Muller
    Department of Vascular Endothelium and Microcirculation, University of Technology Dresden, Fetscherstrasse 74, D 01307 Dresden, Germany
    Exp Biol Med (Maywood) 231:766-71. 2006
    ..Given the nitric oxide-releasing capacity of endothelial ET(B) receptors, this effect may represent a possible vasoprotective mechanism...
  49. ncbi request reprint Ageing as a determinant of renal and vascular disease: role of endothelial factors
    Matthias Barton
    Nephrol Dial Transplant 20:485-90. 2005
  50. ncbi request reprint Postmenopausal hormone-replacement therapy
    Matthias Barton
    N Engl J Med 346:63-5. 2002
  51. ncbi request reprint In-vivo interaction of nitric oxide and endothelin
    Thomas Lattmann
    J Hypertens 22:1839-40; author reply 1840-3. 2004
  52. ncbi request reprint Role of endothelin receptors for renal protection and survival in hypertension: waiting for clinical trials
    Matthias Barton
    Hypertension 48:834-7. 2006
  53. ncbi request reprint Protective role of ETA endothelin receptors during the acute phase of Trypanosoma cruzi infection in rats
    Elizabeth R S Camargos
    Departamento de Morfologia, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais UFMG, Av Antonio Carlos 6627, P O Box 486, CEP 31270 901 Belo Horizonte, MG, Brazil
    Microbes Infect 6:650-6. 2004
    ..Impairment of the endothelium-dependent vasodilatation favors hazardous effects. However, blocking endothelin ET(A) receptors can prevent the latter...
  54. ncbi request reprint Chronic ET(A) receptor blockade prevents endothelial dysfunction of small arteries in apolipoprotein E-deficient mice
    Livius V d'Uscio
    Cardiovascular Research, Institute of Physiology, University of Zurich, Ramistrasse 100, CH 1891 Zürich, Switzerland
    Cardiovasc Res 53:487-95. 2002
    ....
  55. ncbi request reprint Protease-activated receptors and EDHF: the icing on the cake?
    Tobias Traupe
    Cardiovasc Res 61:645-7. 2004
  56. ncbi request reprint Role of endothelin during experimental Trypanosoma cruzi infection in rats
    Elizabeth R S Camargos
    Department of Morphology, Instituto de Ciencias Biologicas, Federal University of Minas Gerais, Avenida Antonio Carlos 6627, Belo Horizonte, Minas Gerais, Brazil
    Clin Sci (Lond) 103:64S-67S. 2002
    ..cruzi infection. Moreover, these data suggest that endothelin-1 is a mediator of impaired endothelium-dependent vasomotion in the coronary microcirculation associated with acute T. cruzi infection...
  57. ncbi request reprint Distinct roles of estrogen receptors alpha and beta mediating acute vasodilation of epicardial coronary arteries
    Tobias Traupe
    University Hospital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Hypertension 49:1364-70. 2007
    ..The findings indicate that coronary vascular effects of sex hormones differ with regard to affinity to ERalpha and ERbeta, which will contribute to beneficial and adverse effects of hormone replacement therapy...
  58. ncbi request reprint Hormone replacement therapy and atherosclerosis in postmenopausal women: does aging limit therapeutic benefits?
    Matthias Barton
    Arterioscler Thromb Vasc Biol 27:1669-72. 2007
  59. ncbi request reprint Native and oxidized low-density lipoproteins stimulate endothelin-converting enzyme-1 expression in human endothelial cells
    Bernd Niemann
    Department of Vascular Endothelium and Microcirculation, Medical Faculty Carl Gustav Carus, University of Technology Dresden, D 01307 Dresden, Germany
    Biochem Biophys Res Commun 334:747-53. 2005
    ..Our data provide evidence for a new mechanism how increased LDL plasma levels might contribute to enhanced endothelin-1 release in patients with hypercholesterolemia...