Silvia Arber


Affiliation: University of Basel
Country: Switzerland


  1. Ferreira Pinto M, Ruder L, Capelli P, Arber S. Connecting Circuits for Supraspinal Control of Locomotion. Neuron. 2018;100:361-374 pubmed publisher
    ..We conclude that the emerging logic of supraspinal circuit organization helps to understand how locomotor programs from exploration to hunting and escape are regulated by the brain. ..
  2. Takeoka A, Arber S. Functional Local Proprioceptive Feedback Circuits Initiate and Maintain Locomotor Recovery after Spinal Cord Injury. Cell Rep. 2019;27:71-85.e3 pubmed publisher
    ..Our study reveals that PAs interacting with local spinal circuits serve as a continued driving force to initiate and maintain locomotor output after injury. ..
  3. Heindorf M, Arber S, Keller G. Mouse Motor Cortex Coordinates the Behavioral Response to Unpredicted Sensory Feedback. Neuron. 2018;99:1040-1054.e5 pubmed publisher
    ..Our results are consistent with a role of M1 in the detection of sensory perturbations that result in deviations from intended motor state and the initiation of an appropriate corrective response. ..
  4. Arber S. FoxP1: conducting the Hox symphony in spinal motor neurons. Nat Neurosci. 2008;11:1122-4 pubmed publisher
  5. Arber S. Motor circuits in action: specification, connectivity, and function. Neuron. 2012;74:975-89 pubmed publisher
    ..This Review highlights key examples of how developmental specification dictates organization of motor circuit connectivity and thereby controls movement. ..
  6. Goetz C, Pivetta C, Arber S. Distinct limb and trunk premotor circuits establish laterality in the spinal cord. Neuron. 2015;85:131-44 pubmed publisher
    ..Together, our findings provide insight into principles of circuit organization underlying weighted lateralization of movement. ..
  7. Satoh D, Pudenz C, Arber S. Context-Dependent Gait Choice Elicited by EphA4 Mutation in Lbx1 Spinal Interneurons. Neuron. 2016;89:1046-58 pubmed publisher
    ..Together, our findings reveal the behavioral and circuit-level impact of conditional EphA4 mutation in a transcriptionally defined spinal interneuron subpopulation. ..
  8. Ruder L, Takeoka A, Arber S. Long-Distance Descending Spinal Neurons Ensure Quadrupedal Locomotor Stability. Neuron. 2016;92:1063-1078 pubmed publisher
    ..Together, our results implicate a highly organized long-distance projection system of spinal origin in the control of postural body stabilization and reliability during quadrupedal locomotion. ..
  9. Esposito M, Arber S. Motor Control: Illuminating an Enigmatic Midbrain Locomotor Center. Curr Biol. 2016;26:R291-3 pubmed publisher
    ..A recent study has functionally disentangled the hitherto enigmatic mesencephalic locomotor region of the brain on the basis of cell type diversity and identified differential upstream regulatory pathways. ..

More Information


  1. Takeoka A, Vollenweider I, Courtine G, Arber S. Muscle spindle feedback directs locomotor recovery and circuit reorganization after spinal cord injury. Cell. 2014;159:1626-39 pubmed publisher
    ..Our findings reveal an essential role for muscle spindle feedback in directing basic locomotor recovery and facilitating circuit reorganization after spinal cord injury. ..
  2. Basaldella E, Takeoka A, Sigrist M, Arber S. Multisensory Signaling Shapes Vestibulo-Motor Circuit Specificity. Cell. 2015;163:301-12 pubmed publisher
    ..Thus, two sensory signaling systems interact to establish complementary synaptic input patterns to the final site of motor output processing. ..
  3. Pivetta C, Esposito M, Sigrist M, Arber S. Motor-circuit communication matrix from spinal cord to brainstem neurons revealed by developmental origin. Cell. 2014;156:537-48 pubmed publisher