Affiliation: University of Fribourg
- Notch signaling in the brain: in good and bad timesLavinia Alberi
Unit of Anatomy, Department of Medicine, University of Fribourg, Switzerland
Ageing Res Rev 12:801-14. 2013....
- Neonatal stroke in mice causes long-term changes in neuronal Notch-2 expression that may contribute to prolonged injuryLavinia Alberi
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Stroke 41:S64-71. 2010..The purpose of this study was to understand whether Notch-2 is induced after neonatal stroke and to investigate its functional relevance...
- Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networksLavinia Alberi
Institute for Cell Engineering, Neuroregeneration Program, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Neuron 69:437-44. 2011..Thus, Notch signaling is dynamically regulated in response to neuronal activity, Arc/Arg3.1 is a context-dependent Notch regulator, and Notch1 is required for the synaptic plasticity that contributes to memory formation...
- The calcium-binding protein parvalbumin modulates the firing 1 properties of the reticular thalamic nucleus bursting neuronsLavinia Alberi
Unit of Anatomy, Department of Medicine, University of Fribourg, Fribourg, Switzerland
J Neurophysiol 109:2827-41. 2013..2 channels and the dynamics of burst discharges of RTN cells, which in turn regulate the activity in the thalamocortical circuit...
- Notch1 activity in the olfactory bulb is odour-dependent and contributes to olfactory behaviourEmanuele Brai
Unit of Anatomy, Department of Medicine, University of Fribourg, Route de Gockel, 1, Fribourg, Switzerland
Eur J Neurosci 40:3436-49. 2014..This indicates, for the first time, that Notch1 is involved in olfactory processing and may contribute to olfactory behaviour. ..
- Monitoring Notch activity in the mouseSwananda Marathe
Unit of Anatomy, Department of Medicine, University of Fribourg, Rue A Gockel 1, 1700, Fribourg, Switzerland
Methods Mol Biol 1187:115-29. 2014..In addition, using the appropriate modifications, the Notch reporter systems can also be used to monitor Notch activity in other organs of the mouse such as retina, skin, skeletal muscle, and cancer cells. ..
- The nuclear receptor REV-ERBα regulates Fabp7 and modulates adult hippocampal neurogenesisAnna Schnell
Dept of Biology, Unit of Biochemistry, University of Fribourg, Fribourg, Switzerland
PLoS ONE 9:e99883. 2014..These results suggest an important role of Rev-erbα and Fabp7 in adult neurogenesis, which may open new avenues for treatment of gliomas as well as neurological diseases such as depression and Alzheimer. ..
- Dopamine deficiency increases synchronized activity in the rat subthalamic nucleusAlessandra Lintas
Dept of Medicine Unit of Anatomy, University of Fribourg, Switzerland
Brain Res 1434:142-51. 2012..This article is part of a Special Issue entitled 'Neural Coding'...
- Notch in the vertebrate nervous system: an old dog with new tricksTarran Pierfelice
Institute for Cell Engineering, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Neuron 69:840-55. 2011..Here, focusing primarily on vertebrates, we review the current literature on Notch signaling in the nervous system, and highlight numerous recent studies that have generated interesting and unexpected advances...