Affiliation: University of Fribourg
- Neonatal stroke in mice causes long-term changes in neuronal Notch-2 expression that may contribute to prolonged injuryLavinia Alberi
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Stroke 41:S64-71. 2010..The purpose of this study was to understand whether Notch-2 is induced after neonatal stroke and to investigate its functional relevance...
- Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networksLavinia Alberi
Institute for Cell Engineering, Neuroregeneration Program, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Neuron 69:437-44. 2011..Thus, Notch signaling is dynamically regulated in response to neuronal activity, Arc/Arg3.1 is a context-dependent Notch regulator, and Notch1 is required for the synaptic plasticity that contributes to memory formation...
- Notch in the vertebrate nervous system: an old dog with new tricksTarran Pierfelice
Institute for Cell Engineering, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Neuron 69:840-55. 2011..Here, focusing primarily on vertebrates, we review the current literature on Notch signaling in the nervous system, and highlight numerous recent studies that have generated interesting and unexpected advances...