Research Topics
Genomes and Genes | Ramon F ThaliSummaryAffiliation: Swiss Federal Institute of Technology Country: Switzerland Publications
| Collaborators
|
Detail Information
Publications
Novel candidate substrates of AMP-activated protein kinase identified in red blood cell lysatesRamon F Thali
Institute of Cell Biology, ETH Zurich, Zurich, Switzerland
Biochem Biophys Res Commun 398:296-301. 2010..These data tie in with the phenotypic observations of AMPKalpha1-deficient RBC and provide reference for future studies...
PKA phosphorylates and inactivates AMPKalpha to promote efficient lipolysisNabil Djouder
Institute of Cell Biology, ETH Zurich, Zurich, Switzerland
EMBO J 29:469-81. 2010..These results suggest a new mechanism of negative regulation of AMPK activity by PKA that is important for converting a lipolytic signal into an effective lipolytic response...
Tracking and quantification of 32P-labeled phosphopeptides in liquid chromatography matrix-assisted laser desorption/ionization mass spectrometryRoland D Tuerk
Institute of Cell Biology, Department of Biology, ETH Zurich, 8093 Zurich, Switzerland
Anal Biochem 390:141-8. 2009..However, accurate analysis of defined areas within single spots suggests that, rather than such quantitative differences, mainly the manner of matrix crystallization significantly affects ionization of phosphopeptides...
Homo-oligomerization and activation of AMP-activated protein kinase are mediated by the kinase domain alphaG-helixRoland Scholz
Department of Biology, Institute of Cell Biology, ETH Zurich, 8093 Zurich, Switzerland
J Biol Chem 284:27425-37. 2009..Our data suggest a physiological role for the hydrophobic alphaG-helix residues in homo-oligomerization of heterotrimers and cellular interactions, in particular with upstream kinases, indicating an additional level of AMPK regulation...
New candidate targets of AMP-activated protein kinase in murine brain revealed by a novel multidimensional substrate-screen for protein kinasesRoland D Tuerk
Institutes of Cell Biology and Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland
J Proteome Res 6:3266-77. 2007..Our data suggests that signaling by AMPK in brain is likely to be involved in the regulation of pathways that have not yet been linked to this kinase...
Autoactivation of transforming growth factor beta-activated kinase 1 is a sequential bimolecular processRoland Scholz
Department of Biology, Institute of Cell Biology, ETH Zurich, 8093 Zurich, Switzerland
J Biol Chem 285:25753-66. 2010..Finally, we present a model for the chronological order of events governing TAB1-induced TAK1 autoactivation...
