Otto Seppälä

Summary

Affiliation: Swiss Federal Institute of Aquatic Science and Technology
Country: Switzerland

Publications

  1. doi request reprint Activation of the immune defence of the freshwater snail Lymnaea stagnalis by different immune elicitors
    Otto Seppälä
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland
    J Exp Biol 216:2902-7. 2013
  2. doi request reprint Reciprocal interaction matrix reveals complex genetic and dose-dependent specificity among coinfecting parasites
    Otto Seppälä
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland
    Am Nat 180:306-15. 2012
  3. doi request reprint Food makes you a target: disentangling genetic, physiological, and behavioral effects determining susceptibility to infection
    Otto Seppälä
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland ETH Zürich, Institute of Integrative Biology, 8092 Zurich, Switzerland
    Evolution 65:1367-75. 2011
  4. pmc Interactions among co-infecting parasite species: a mechanism maintaining genetic variation in parasites?
    Otto Seppälä
    Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland
    Proc Biol Sci 276:691-7. 2009
  5. pmc Immune defence under extreme ambient temperature
    Otto Seppälä
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland
    Biol Lett 7:119-22. 2011
  6. pmc Host manipulation as a parasite transmission strategy when manipulation is exploited by non-host predators
    Otto Seppälä
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland
    Biol Lett 4:663-6. 2008
  7. pmc Host manipulation by parasites in the world of dead-end predators: adaptation to enhance transmission?
    Otto Seppälä
    Department of Aquatic Ecology ECO, Eawag, Uberlandstrasse 133, PO Box 611, 8600 Dubendorf, Switzerland
    Proc Biol Sci 275:1611-5. 2008
  8. doi request reprint Phenotypic variation in infectivity of Diplostomum spathaceum cercariae within a population
    O Seppälä
    Department of Biological and Environmental Science, University of Jyvaskyla, Finland
    J Parasitol 93:1244-6. 2007
  9. doi request reprint Eye fluke-induced cataracts in natural fish populations: is there potential for host manipulation?
    O Seppälä
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, and ETH Zurich, Institute of Integrative Biology, Uberlandstrasse 133, PO Box 611, CH 8600 Dubendorf, Switzerland
    Parasitology 138:209-14. 2011
  10. doi request reprint Maintenance of genetic variation in immune defense of a freshwater snail: role of environmental heterogeneity
    Otto Seppälä
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland, and ETH Zurich, Institute of Integrative Biology IBZ, 8092 Zurich, Switzerland
    Evolution 64:2397-407. 2010

Detail Information

Publications16

  1. doi request reprint Activation of the immune defence of the freshwater snail Lymnaea stagnalis by different immune elicitors
    Otto Seppälä
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland
    J Exp Biol 216:2902-7. 2013
    ..Our findings suggest potentially complicated relationships among immune traits, and propose suitable techniques for ecological studies in this study system. ..
  2. doi request reprint Reciprocal interaction matrix reveals complex genetic and dose-dependent specificity among coinfecting parasites
    Otto Seppälä
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland
    Am Nat 180:306-15. 2012
    ..gasterostei. The relative magnitude of these effects, however, depended on the exposure dose, suggesting that ecological factors can modify genetic interactions between parasites...
  3. doi request reprint Food makes you a target: disentangling genetic, physiological, and behavioral effects determining susceptibility to infection
    Otto Seppälä
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland ETH Zürich, Institute of Integrative Biology, 8092 Zurich, Switzerland
    Evolution 65:1367-75. 2011
    ..Feeding treatments also affected the family-level variation in snail susceptibility, suggesting that the relative susceptibility of host genotypes was context dependent...
  4. pmc Interactions among co-infecting parasite species: a mechanism maintaining genetic variation in parasites?
    Otto Seppälä
    Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland
    Proc Biol Sci 276:691-7. 2009
    ..gasterostei strains was independent of exposure type. These results suggest that interactions among parasite species may be strain specific and potentially promote maintenance of genetic polymorphism in parasite populations...
  5. pmc Immune defence under extreme ambient temperature
    Otto Seppälä
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland
    Biol Lett 7:119-22. 2011
    ..This suggests that the effect of high temperature on snail susceptibility to infections may vary across different pathogens because different components of invertebrate immune defence have different roles in resistance...
  6. pmc Host manipulation as a parasite transmission strategy when manipulation is exploited by non-host predators
    Otto Seppälä
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland
    Biol Lett 4:663-6. 2008
    ..Therefore, nonspecific host manipulation may evolve in nature, but the adaptive value of a certain manipulation strategy can vary among different parasite populations depending on the variation in initial predation risk...
  7. pmc Host manipulation by parasites in the world of dead-end predators: adaptation to enhance transmission?
    Otto Seppälä
    Department of Aquatic Ecology ECO, Eawag, Uberlandstrasse 133, PO Box 611, 8600 Dubendorf, Switzerland
    Proc Biol Sci 275:1611-5. 2008
    ..However, the increased predation vulnerability of the infected isopods was higher towards perch. This suggests that, despite the costs due to non-host predation, host manipulation may still be advantageous for the parasite...
  8. doi request reprint Phenotypic variation in infectivity of Diplostomum spathaceum cercariae within a population
    O Seppälä
    Department of Biological and Environmental Science, University of Jyvaskyla, Finland
    J Parasitol 93:1244-6. 2007
    ..5% and 87.5%. Depending on the source of variation, this may have important ecological and evolutionary implications for both natural parasite populations and those occurring in aquaculture...
  9. doi request reprint Eye fluke-induced cataracts in natural fish populations: is there potential for host manipulation?
    O Seppälä
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, and ETH Zurich, Institute of Integrative Biology, Uberlandstrasse 133, PO Box 611, CH 8600 Dubendorf, Switzerland
    Parasitology 138:209-14. 2011
    ..However, we observed such cataracts only in species with the highest parasite abundances, which suggests that only certain hosts may be strongly affected by the infection...
  10. doi request reprint Maintenance of genetic variation in immune defense of a freshwater snail: role of environmental heterogeneity
    Otto Seppälä
    Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland, and ETH Zurich, Institute of Integrative Biology IBZ, 8092 Zurich, Switzerland
    Evolution 64:2397-407. 2010
    ..Thus, our findings support the idea that environmental heterogeneity may promote maintenance of genetic variation in immune defense, but also suggest that different immune traits might not respond similarly to environmental variation...
  11. doi request reprint Eye fluke infection and lens size reduction in fish: a quantitative analysis
    Anssi Karvonen
    Department of Biological and Environmental Science, University of Jyvaskyla, PO Box 35, 40014 Jyvaskyla, Finland
    Dis Aquat Organ 80:21-6. 2008
    ..It may also directly affect the overall optical performance of the lens and already impair host vision at low intensities of infection...
  12. ncbi request reprint Resistance against eye flukes: naïve versus previously infected fish
    Anssi Karvonen
    Department of Biological and Environmental Science, University of Jyvaskyla, P O Box 35, 40014, Jyvaskyla, Finland
    Parasitol Res 95:55-9. 2005
    ..0-89.1%. Parasite establishment was also affected by fish host density as fewer parasites were found in fish in higher densities. The implications of these results for the fish-farming industry and fish-stocking protocols are discussed...
  13. ncbi request reprint Transmission dynamics of a trematode parasite: exposure, acquired resistance and parasite aggregation
    Anssi Karvonen
    Department of Biological and Environmental Science, P O Box 35, 40014 University of Jyväskylä, Finland
    Parasitol Res 92:183-8. 2004
    ..This is one of the few studies to demonstrate the development of resistance in fish against the parasite under natural conditions, and to attempt to separate exposure and susceptibility as causative agents of parasite aggregation...
  14. doi request reprint Host immunization shapes interspecific associations in trematode parasites
    Anssi Karvonen
    Department of Biological and Environmental Science, Centre of Excellence in Evolutionary Research, University of Jyvaskyla, Jyvaskyla, Finland
    J Anim Ecol 78:945-52. 2009
    ..This implies that correlative results suggesting non-interactive community structure in general may be obscured by the sequence of previous parasite exposure and corresponding dynamics of host immunization...
  15. ncbi request reprint Dynamics of Diplostomum spathaceum infection in snail hosts at a fish farm
    Anssi Karvonen
    Department of Biological and Environmental Science, University of Jyvaskyla, P O Box 35, 40014, Jyvaskyla, Finland
    Parasitol Res 99:341-5. 2006
    ..spathaceum, but also that snail prevention at farms could be conducted more efficiently by considering both size-dependent infection and the timing of cercarial release...
  16. pmc Are sick individuals weak competitors? Competitive ability of snails parasitized by a gigantism-inducing trematode
    Otto Seppälä
    Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland Department of Aquatic Ecology, Eawag, Dubendorf, Switzerland
    PLoS ONE 8:e79366. 2013
    ..The latter effect, however, was relatively weak suggesting that the effects of the parasite on snail physiology may partly override each other in determining competitive ability. ..