- Function and regulation of protein neddylation. 'Protein modifications: beyond the usual suspects' review seriesGwénaël Rabut
Swiss Federal Institute of Technology Zurich ETH, Institute of Biochemistry, 8093 Zurich, Switzerland
EMBO Rep 9:969-76. 2008..As numerous neddylation substrates probably remain to be discovered, we propose some criteria that could be used as guidelines for the characterization of neddylated proteins...
- The TFIIH subunit Tfb3 regulates cullin neddylationGwénaël Rabut
Institute of Biochemistry, ETH Zurich, Zurich, Switzerland
Mol Cell 43:488-95. 2011..Together, these results suggest that the conserved RING domain protein Tfb3 controls activation of a subset of cullins...
- Structural analysis of the conserved ubiquitin-binding motifs (UBMs) of the translesion polymerase iota in complex with ubiquitinDaniel Burschowsky
Institute of Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland
J Biol Chem 286:1364-73. 2011..Indeed, yeast cells expressing ubiquitin mutants specifically defective for UBM binding are viable but sensitive to DNA damaging conditions that require TLS for repair...
- Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNAIram Waris Zaidi
Institute of Biochemistry, Swiss Federal Institute of Technology Zurich ETH, ETH Hoenggerberg, 8093 Zurich, Switzerland
EMBO Rep 9:1034-40. 2008..Taken together, our data suggest that the Rtt101(Mms1) ubiquitin ligase complex might be required to reorganize replication forks that encounter DNA lesions...