Urs Meyer

Summary

Affiliation: Swiss Federal Institute of Technology
Country: Switzerland

Publications

  1. ncbi request reprint Towards an immuno-precipitated neurodevelopmental animal model of schizophrenia
    Urs Meyer
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology Zurich, Schorenstrasse 16, Schwerzenbach 8603, Switzerland
    Neurosci Biobehav Rev 29:913-47. 2005
  2. pmc Prenatal immune activation induces maturation-dependent alterations in the prefrontal GABAergic transcriptome
    Juliet Richetto
    To whom correspondence should be addressed tel 41 44 655 7403, fax 41 44 655 7203, E mail
    Schizophr Bull 40:351-61. 2014
  3. doi request reprint Developmental neuroinflammation and schizophrenia
    Urs Meyer
    Physiology and Behaviour Laboratory, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
    Prog Neuropsychopharmacol Biol Psychiatry 42:20-34. 2013
  4. ncbi request reprint To poly(I:C) or not to poly(I:C): advancing preclinical schizophrenia research through the use of prenatal immune activation models
    Urs Meyer
    Laboratory of Behavioral Neurobiology, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
    Neuropharmacology 62:1308-21. 2012
  5. doi request reprint Epidemiology-driven neurodevelopmental animal models of schizophrenia
    Urs Meyer
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, CH 8603 Schwerzenbach, Switzerland
    Prog Neurobiol 90:285-326. 2010
  6. doi request reprint Prenatal exposure to infection: a primary mechanism for abnormal dopaminergic development in schizophrenia
    Urs Meyer
    Laboratory of Behavioral Neurobiology, ETH Zurich, Schorenstrasse 16, Schwerzenbach, Switzerland
    Psychopharmacology (Berl) 206:587-602. 2009
  7. pmc Schizophrenia and autism: both shared and disorder-specific pathogenesis via perinatal inflammation?
    Urs Meyer
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology ETH Zurich, 8603 Schwerzenbach, Switzerland
    Pediatr Res 69:26R-33R. 2011
  8. doi request reprint Anti-inflammatory signaling in schizophrenia
    Urs Meyer
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
    Brain Behav Immun 25:1507-18. 2011
  9. doi request reprint Inflammatory processes in schizophrenia: a promising neuroimmunological target for the treatment of negative/cognitive symptoms and beyond
    Urs Meyer
    Physiology and Behaviour Laboratory, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
    Pharmacol Ther 132:96-110. 2011
  10. ncbi request reprint Preliminary evidence for a modulation of fetal dopaminergic development by maternal immune activation during pregnancy
    U Meyer
    Laboratory of Behavioural Neurobiology, ETH Zurich, Schorenstrasse 16, Schwerzenbach, Switzerland
    Neuroscience 154:701-9. 2008

Collaborators

Detail Information

Publications52

  1. ncbi request reprint Towards an immuno-precipitated neurodevelopmental animal model of schizophrenia
    Urs Meyer
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology Zurich, Schorenstrasse 16, Schwerzenbach 8603, Switzerland
    Neurosci Biobehav Rev 29:913-47. 2005
    ..It is, sui generis, ideally suited for the investigation of the neuropsychoimmunological mechanisms implicated in the developmental aetiology and disease processes of schizophrenia...
  2. pmc Prenatal immune activation induces maturation-dependent alterations in the prefrontal GABAergic transcriptome
    Juliet Richetto
    To whom correspondence should be addressed tel 41 44 655 7403, fax 41 44 655 7203, E mail
    Schizophr Bull 40:351-61. 2014
    ....
  3. doi request reprint Developmental neuroinflammation and schizophrenia
    Urs Meyer
    Physiology and Behaviour Laboratory, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
    Prog Neuropsychopharmacol Biol Psychiatry 42:20-34. 2013
    ....
  4. ncbi request reprint To poly(I:C) or not to poly(I:C): advancing preclinical schizophrenia research through the use of prenatal immune activation models
    Urs Meyer
    Laboratory of Behavioral Neurobiology, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
    Neuropharmacology 62:1308-21. 2012
    ....
  5. doi request reprint Epidemiology-driven neurodevelopmental animal models of schizophrenia
    Urs Meyer
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, CH 8603 Schwerzenbach, Switzerland
    Prog Neurobiol 90:285-326. 2010
    ....
  6. doi request reprint Prenatal exposure to infection: a primary mechanism for abnormal dopaminergic development in schizophrenia
    Urs Meyer
    Laboratory of Behavioral Neurobiology, ETH Zurich, Schorenstrasse 16, Schwerzenbach, Switzerland
    Psychopharmacology (Berl) 206:587-602. 2009
    ....
  7. pmc Schizophrenia and autism: both shared and disorder-specific pathogenesis via perinatal inflammation?
    Urs Meyer
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology ETH Zurich, 8603 Schwerzenbach, Switzerland
    Pediatr Res 69:26R-33R. 2011
    ....
  8. doi request reprint Anti-inflammatory signaling in schizophrenia
    Urs Meyer
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
    Brain Behav Immun 25:1507-18. 2011
    ....
  9. doi request reprint Inflammatory processes in schizophrenia: a promising neuroimmunological target for the treatment of negative/cognitive symptoms and beyond
    Urs Meyer
    Physiology and Behaviour Laboratory, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
    Pharmacol Ther 132:96-110. 2011
    ....
  10. ncbi request reprint Preliminary evidence for a modulation of fetal dopaminergic development by maternal immune activation during pregnancy
    U Meyer
    Laboratory of Behavioural Neurobiology, ETH Zurich, Schorenstrasse 16, Schwerzenbach, Switzerland
    Neuroscience 154:701-9. 2008
    ....
  11. pmc Evaluating early preventive antipsychotic and antidepressant drug treatment in an infection-based neurodevelopmental mouse model of schizophrenia
    Urs Meyer
    Laboratory of Behavioral Neurobiology, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, CH 8603 Schwerzenbach, Switzerland
    Schizophr Bull 36:607-23. 2010
    ....
  12. ncbi request reprint Neural basis of psychosis-related behaviour in the infection model of schizophrenia
    Urs Meyer
    Laboratory of Behavioural Neurobiology, ETH Zurich, Schorenstrasse 16, Schwerzenbach 8603, Switzerland
    Behav Brain Res 204:322-34. 2009
    ....
  13. doi request reprint Chronic clozapine treatment improves prenatal infection-induced working memory deficits without influencing adult hippocampal neurogenesis
    Urs Meyer
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
    Psychopharmacology (Berl) 208:531-43. 2010
    ..Converging evidence indicates that prenatal exposure to immune challenge can induce long-term cognitive deficits relevant to schizophrenia. Such cognitive impairments may be related to deficient hippocampal neurogenesis at adult age...
  14. doi request reprint In-vivo rodent models for the experimental investigation of prenatal immune activation effects in neurodevelopmental brain disorders
    Urs Meyer
    Swiss Federal Institute of Technology Zurich, Schwerzenbach, Switzerland
    Neurosci Biobehav Rev 33:1061-79. 2009
    ....
  15. ncbi request reprint Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice
    Urs Meyer
    Laboratory of Behavioral Neurobiology, ETH Zurich, Schwerzenbach, Switzerland
    Brain Behav Immun 22:469-86. 2008
    ....
  16. ncbi request reprint The time of prenatal immune challenge determines the specificity of inflammation-mediated brain and behavioral pathology
    Urs Meyer
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology Zurich, CH 8603 Schwerzenbach, Switzerland
    J Neurosci 26:4752-62. 2006
    ..Thus, the middle and late gestation periods correspond to two windows with differing vulnerability to adult behavioral dysfunction, brain neuropathology in early adolescence, and of the acute cytokine responses in the fetal brain...
  17. ncbi request reprint Relative prenatal and postnatal maternal contributions to schizophrenia-related neurochemical dysfunction after in utero immune challenge
    Urs Meyer
    Laboratory of Behavioural Neurobiology, ETH Zurich, Schwerzenbach, Switzerland
    Neuropsychopharmacology 33:441-56. 2008
    ....
  18. ncbi request reprint Immunological stress at the maternal-foetal interface: a link between neurodevelopment and adult psychopathology
    Urs Meyer
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology Zurich, Schorenstrasse 16, CH 8603 Schwerzenbach, Switzerland
    Brain Behav Immun 20:378-88. 2006
    ....
  19. ncbi request reprint Disruption of the US pre-exposure effect and latent inhibition in two-way active avoidance by systemic amphetamine in C57BL/6 mice
    Tilly Chang
    Laboratory of Behavioural Neurobiology, ETH Zurich, Schorenstrasse 16, 8603, Schwerzenbach, Switzerland
    Psychopharmacology (Berl) 191:211-21. 2007
    ....
  20. doi request reprint A longitudinal examination of the neurodevelopmental impact of prenatal immune activation in mice reveals primary defects in dopaminergic development relevant to schizophrenia
    Stéphanie Vuillermot
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology Zurich, 8603 Schwerzenbach, Switzerland
    J Neurosci 30:1270-87. 2010
    ..Early interventions targeting the developing dopamine system may open new avenues for a successful attenuation or even prevention of psychotic disorders following neurodevelopmental disruption of dopamine functions...
  21. ncbi request reprint Prenatal and postnatal maternal contributions in the infection model of schizophrenia
    Urs Meyer
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology Zurich, Schorenstrasse 16, 8603, Schwerzenbach, Switzerland
    Exp Brain Res 173:243-57. 2006
    ....
  22. doi request reprint Stress in puberty unmasks latent neuropathological consequences of prenatal immune activation in mice
    Sandra Giovanoli
    Physiology and Behavior Laboratory, Swiss Federal Institute of Technology ETH Zurich, 8603 Schwerzenbach, Switzerland
    Science 339:1095-9. 2013
    ....
  23. doi request reprint Cognitive impairment following prenatal immune challenge in mice correlates with prefrontal cortical AKT1 deficiency
    Byron K Y Bitanihirwe
    Laboratory of Behavioural Neurobiology, ETH Zurich, Switzerland
    Int J Neuropsychopharmacol 13:981-96. 2010
    ....
  24. pmc Late prenatal immune activation in mice leads to behavioral and neurochemical abnormalities relevant to the negative symptoms of schizophrenia
    Byron K Y Bitanihirwe
    Department of Biology, Swiss Federal Institute of Technology ETH Zurich, Schwerzenbach, Switzerland
    Neuropsychopharmacology 35:2462-78. 2010
    ....
  25. ncbi request reprint Chronic high fat diet consumption impairs sensorimotor gating in mice
    Marie A Labouesse
    Physiology and Behavior Laboratory, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland Electronic address
    Psychoneuroendocrinology 38:2562-74. 2013
    ..It is likely that the disrupting effects of HFD on sensorimotor gating involve, at least in part, dopaminergic mechanisms. ..
  26. doi request reprint Prenatal immune activation interacts with genetic Nurr1 deficiency in the development of attentional impairments
    Stéphanie Vuillermot
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology Zurich, 8603 Schwerzenbach, Switzerland
    J Neurosci 32:436-51. 2012
    ....
  27. ncbi request reprint The neurodevelopmental impact of prenatal infections at different times of pregnancy: the earlier the worse?
    Urs Meyer
    Laboratory of Behavioral Neurobiology, ETH Zurich, Switzerland
    Neuroscientist 13:241-56. 2007
    ....
  28. pmc A review of the fetal brain cytokine imbalance hypothesis of schizophrenia
    Urs Meyer
    Laboratory of Behavioural Neurobiology, ETH Zurich, Schorenstrasse 16, CH 8603 Schwerzenbach, Switzerland
    Schizophr Bull 35:959-72. 2009
    ....
  29. pmc Administration of the Y2 receptor agonist PYY3-36 in mice induces multiple behavioral changes relevant to schizophrenia
    Ulrike Stadlbauer
    Physiology and Behavior Laboratory, Swiss Federal Institute of Technology ETH Zurich, Schwerzenbach, Switzerland
    Neuropsychopharmacology 38:2446-55. 2013
    ..At least some of the behavioral deficits induced by augmentation of Y2 receptor signaling may involve increased dopaminergic activity...
  30. doi request reprint Nurr1 is not essential for the development of prepulse inhibition deficits induced by prenatal immune activation
    Stéphanie Vuillermot
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
    Brain Behav Immun 25:1316-21. 2011
    ..Our data thus suggest that at least under the present experimental conditions, Nurr1 is not essential for the development of prepulse inhibition deficits induced by prenatal immune activation...
  31. ncbi request reprint Expression of the CS- and US-pre-exposure effects in the conditioned taste aversion paradigm and their abolition following systemic amphetamine treatment in C57BL6/J mice
    Urs Meyer
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology Zurich, Schwerzenbach, Switzerland
    Neuropsychopharmacology 29:2140-8. 2004
    ..The parallel observation in the US-PE effect further indicates that its expression, at least in the present conditioned taste aversion paradigm, may also be under similar influence of the dopaminergic system...
  32. ncbi request reprint Gut vagal afferents differentially modulate innate anxiety and learned fear
    Melanie Klarer
    Physiology and Behavior Laboratory, ETH Zurich, 8603 Schwerzenbach, Switzerland and
    J Neurosci 34:7067-76. 2014
    ..These data add further weight to theories emphasizing an important role of afferent visceral signals in the regulation of emotional behavior. ..
  33. pmc Priming of metabolic dysfunctions by prenatal immune activation in mice: relevance to schizophrenia
    Gustavo Pacheco-López
    Physiology and Behavior Laboratory, Swiss Federal Institute of Technology Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
    Schizophr Bull 39:319-29. 2013
    ....
  34. doi request reprint Relationship between sensorimotor gating deficits and dopaminergic neuroanatomy in Nurr1-deficient mice
    Stéphanie Vuillermot
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
    Exp Neurol 232:22-32. 2011
    ....
  35. ncbi request reprint Anaerobic digestion of alcohol sulfate (anionic surfactant) rich wastewater--batch experiments. Part II: influence of the hydrophobic chain length
    H Feitkenhauer
    Laboratorium für Technische Chemie, ETH Hönggerberg HCI, Zurich, Switzerland
    Bioresour Technol 82:123-9. 2002
    ..The presented data can be used as a basis for the selection of suitable surfactants that do not (or not seriously) inhibit the anaerobic digestion of industrial effluents...
  36. ncbi request reprint Maternal immune activation during pregnancy increases limbic GABAA receptor immunoreactivity in the adult offspring: implications for schizophrenia
    M Nyffeler
    Laboratory of Behavioral Neurobiology, ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
    Neuroscience 143:51-62. 2006
    ....
  37. ncbi request reprint Integration of biotechnological wastewater treatment units in textile finishing factories: from end of the pipe solutions to combined production and wastewater treatment units
    H Feitkenhauer
    Laboratorium für Technische Chemie, ETH Zurich, Universitatstrasse 6, CH 8092, Zurich, Switzerland
    J Biotechnol 89:185-92. 2001
    ..The example of cotton fabric desizing (removing size from the fabric) illustrates how this final step of integration uses the acidic phase bioreactor as a part of the production and allows to close the water cycle of the system...
  38. ncbi request reprint A new method for the fast determination of kinetic parameters in anaerobic digestion processes and application to textile wet processing wastewater
    H Feitkenhauer
    Laboratory of Chemical Engineering and Industrial Chemistry, ETH Zurich, Honggerberg, CH 8093 Zurich, Switzerland
    Water Sci Technol 48:203-10. 2003
    ..It is shown that the simplest method (direct titration) revealed the most important information. The investigated substrates were selected pollutants of textile wet processing wastewater...
  39. ncbi request reprint Factors affecting constancy of acetate concentration and correct determination of methanogenic activity in pH-stat experiments
    M Mösche
    Laboratorium für Technische Chemie, Eidgenossische Technische Hochschule, HCI F 112, Zurich, Switzerland
    Water Sci Technol 48:111-8. 2003
    ..In this way a better constancy of acetate concentration and a more accurate determination of methanogenic activity should be achievable. The accuracy of this method is limited by the stability of pH-electrode calibration parameters...
  40. ncbi request reprint Adult behavioral and pharmacological dysfunctions following disruption of the fetal brain balance between pro-inflammatory and IL-10-mediated anti-inflammatory signaling
    U Meyer
    Laboratory of Behavioural Neurobiology, ETH Zurich, Schwerzenbach, Switzerland
    Mol Psychiatry 13:208-21. 2008
    ..Hence, shifts of the balance between pro- and anti-inflammatory cytokine classes may be a critical determinant of the final impact on neurodevelopment following early life infection or innate immune imbalances...
  41. ncbi request reprint Toxicity of linear alkylbenzene sulfonate in anaerobic digestion: influence of exposure time
    M Mösche
    Laboratory of Technical Chemistry, Swiss Federal Institute of Technology ETH, Zurich
    Water Res 36:3253-60. 2002
    ..This discrepancy is explained by adsorption of the surfactant to the biomass. Finally, the importance of the presented kinetic model and the significance of surfactant toxicity for anaerobic digestion are discussed...
  42. ncbi request reprint Anaerobic digestion of alcohol sulfate (anionic surfactant) rich wastewater--batch experiments. Part I: influence of the surfactant concentration
    H Feitkenhauer
    Laboratorium für Technische Chemie, ETH, Hönggerberg HCI, Zurich, Switzerland
    Bioresour Technol 82:115-21. 2002
    ..The surfactant caused a high temporary accumulation of intermediates like volatile fatty acids. At the highest loading (217 g DS/kg CDW) the conversion of the substrate to methane was only minor...
  43. doi request reprint Response to comment on "Stress in puberty unmasks latent neuropathological consequences of prenatal immune activation in mice"
    Sandra Giovanoli
    Physiology and Behavior Laboratory, Swiss Federal Institute of Technology ETH Zurich, Schwerzenbach, Switzerland
    Science 340:811. 2013
    ..His theory-biased criticism is disproportionate in view of the robustness of our findings (even if different statistical methods are applied) and falls short in explaining the postpubertal onset of effects...
  44. ncbi request reprint Single and combined effects of prenatal immune activation and peripubertal stress on parvalbumin and reelin expression in the hippocampal formation
    Sandra Giovanoli
    Physiology and Behavior Laboratory, ETH Zurich, Schwerzenbach, Switzerland
    Brain Behav Immun 40:48-54. 2014
    ....
  45. doi request reprint The Y2 receptor agonist PYY(3-36) increases the behavioural response to novelty and acute dopaminergic drug challenge in mice
    Ulrike Stadlbauer
    Physiology and Behaviour Laboratory, Swiss Federal Institute of Technology ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland
    Int J Neuropsychopharmacol 17:407-19. 2014
    ..These effects do not seem to involve direct activation of midbrain dopamine cells but instead are associated with neuronal activation in the major input areas of the mesoaccumbal and nigrostriatal pathways...
  46. pmc Deficient maternal care resulting from immunological stress during pregnancy is associated with a sex-dependent enhancement of conditioned fear in the offspring
    Severin Schwendener
    Laboratory of Behavioural Neurobiology, ETH Zurich, Schorenstrasse 16, 8603, Schwerzenbach, Switzerland
    J Neurodev Disord 1:15-32. 2009
    ..This may have important implications for the identification and characterization of early-life risk factors involved in the developmental etiology of fear-related neuropsychiatric disorders...
  47. ncbi request reprint The neuropathological contribution of prenatal inflammation to schizophrenia
    Urs Meyer
    Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology, Zurich, Switzerland
    Expert Rev Neurother 11:29-32. 2011
    ....
  48. ncbi request reprint On-line titration of non-ionic surfactants in wastewater treatment plants using a specific electrode
    H Feitkenhauer
    Laboratorium für Technische Chemie, ETH Zurich, HCI, Switzerland
    Water Sci Technol 45:61-8. 2002
    ..The software used for the process control of a lab-scale anaerobic treatment plant was also used to evaluate the obtained titration curves. This allowed performing the titrations without using a more expensive titrator...
  49. ncbi request reprint Fuzzy-control for improved nitrogen removal and energy saving in WWT-plants with pre-denitrification
    U Meyer
    Vivendi Water Germany, Walter Köhn Str 1a, 04356 Leipzig, Germany
    Water Sci Technol 47:69-76. 2003
    ..It therefore can be expected that the developed fuzzy-control systems will be accepted by the operating personnel in wastewater treatment plants...
  50. ncbi request reprint The influence of an increased cobalt supply to dairy cows on the vitamin B status of their calves
    K Stemme
    Institute of Animal Nutrition, Federal Agricultural Research Centre Braunschweig, Germany
    J Anim Physiol Anim Nutr (Berl) 90:173-6. 2006
    ..From these results it can be concluded that cobalt content of 0.13 mg Co/kg DM in the ration based on wilted grass silage seems to be sufficient for pregnant dairy cows...
  51. ncbi request reprint Chronic psychosocial stress regulates the expression of both GR and MR mRNA in the hippocampal formation of tree shrews
    U Meyer
    Division of Neurobiology, German Primate Center,
    Hippocampus 11:329-36. 2001
    ..Moreover, the differential regulation of MR mRNA along the rostrocaudal axis of the hippocampus adds another feature to the heterogenous composition of this structure...
  52. ncbi request reprint Design and performance of a bioreactor system for mechanically promoted three-dimensional tissue engineering
    U Meyer
    Department of Cranio Maxillofacial Surgery, University of Munster, Waldeyerstr 30, D 48149 Munster, Germany
    Br J Oral Maxillofac Surg 44:134-40. 2006
    ..The mechanisms whereby mechanical stimulation leads to a defined cell reaction are not known, but the application of physiological micromovements in extracorporeal tissue chambers is a promising approach to the formation of hard tissue...