L Meinel

Summary

Affiliation: Swiss Federal Institute of Technology
Country: Switzerland

Publications

  1. pmc An experimental animal model of aseptic loosening of hip prostheses in sheep to study early biochemical changes at the interface membrane
    Alexander O El-Warrak
    Musculoskeletal Research Unit, Dept of Veterinary Surgery, University of Zurich, Winterthurerstr, 260, 8057 Zurich, Switzerland
    BMC Musculoskelet Disord 5:7. 2004
  2. ncbi request reprint Silk based biomaterials to heal critical sized femur defects
    L Meinel
    Departments of Biomedical Engineering and Chemical and Biological Engineering, Tufts University, Medford, MA 02155, USA
    Bone 39:922-31. 2006
  3. doi request reprint Insulin-like growth factor I releasing silk fibroin scaffolds induce chondrogenic differentiation of human mesenchymal stem cells
    Lorenz Uebersax
    Institute of Pharmaceutical Sciences, ETH Zurich, Wolfgang Pauli Strasse 10, CH 8093 Zurich, Switzerland
    J Control Release 127:12-21. 2008
  4. pmc Optimization strategies for electrospun silk fibroin tissue engineering scaffolds
    Anne J Meinel
    Institute of Pharmaceutical Sciences, ETH Zurich, Department for Chemistry and Applied Biosciences, HCI J 390 1, Wolfgang Pauli Strasse 10, CH 8093 Zurich, Switzerland
    Biomaterials 30:3058-67. 2009
  5. ncbi request reprint Silk fibroin as an organic polymer for controlled drug delivery
    S Hofmann
    Drug Formulation and Delivery, ETH Zurich, 8093 Zurich, Switzerland
    J Control Release 111:219-27. 2006
  6. ncbi request reprint Stabilizing insulin-like growth factor-I in poly(D,L-lactide-co-glycolide) microspheres
    L Meinel
    Department of Applied BioSciences, Galenical Pharmacy, ETH Zurich, Winterthurer Strasse 190, 8057 Zurich, Switzerland
    J Control Release 70:193-202. 2001
  7. ncbi request reprint Bioreactor cultivation of osteochondral grafts
    G Vunjak-Novakovic
    Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Orthod Craniofac Res 8:209-18. 2005
  8. pmc BMP-silk composite matrices heal critically sized femoral defects
    C Kirker-Head
    Tufts Cummings School of Veterinary Medicine, North Grafton, MA, USA
    Bone 41:247-55. 2007

Collaborators

  • S Hofmann
  • Viola Vogel
  • R Langer
  • Marcos Garcia-Fuentes
  • Anne J Meinel
  • Hans P Merkle
  • Lorenz Uebersax
  • C Kirker-Head
  • D Kaplan
  • G Vunjak-Novakovic
  • Alexander O El-Warrak
  • Enrico Klotzsch
  • Kristopher E Kubow
  • Michael L Smith
  • B von Rechenberg
  • J McCool
  • V Karageorgiou
  • R Fajardo
  • M Curtis
  • L Abrahamsen
  • M Hilbe
  • A Nazarian
  • E Cory
  • H P Merkle
  • O Betz
  • G Altman
  • Joerg Auer
  • Brigitte von Rechenberg
  • Rebecca Schneider
  • Margarete K Akens
  • Marvin Olmstead
  • Regula Bettschart-Wolfisberger

Detail Information

Publications8

  1. pmc An experimental animal model of aseptic loosening of hip prostheses in sheep to study early biochemical changes at the interface membrane
    Alexander O El-Warrak
    Musculoskeletal Research Unit, Dept of Veterinary Surgery, University of Zurich, Winterthurerstr, 260, 8057 Zurich, Switzerland
    BMC Musculoskelet Disord 5:7. 2004
    ....
  2. ncbi request reprint Silk based biomaterials to heal critical sized femur defects
    L Meinel
    Departments of Biomedical Engineering and Chemical and Biological Engineering, Tufts University, Medford, MA 02155, USA
    Bone 39:922-31. 2006
    ..Thus, these new constructs provide an alternative protein-based biomaterial for load bearing applications...
  3. doi request reprint Insulin-like growth factor I releasing silk fibroin scaffolds induce chondrogenic differentiation of human mesenchymal stem cells
    Lorenz Uebersax
    Institute of Pharmaceutical Sciences, ETH Zurich, Wolfgang Pauli Strasse 10, CH 8093 Zurich, Switzerland
    J Control Release 127:12-21. 2008
    ..IGF-I loaded porous SF scaffolds have the potential to provide chondrogenic stimuli to hMSC. Evidence for in vivo cartilage (re)generation must be demonstrated by future, pre-clinical proof of concept studies...
  4. pmc Optimization strategies for electrospun silk fibroin tissue engineering scaffolds
    Anne J Meinel
    Institute of Pharmaceutical Sciences, ETH Zurich, Department for Chemistry and Applied Biosciences, HCI J 390 1, Wolfgang Pauli Strasse 10, CH 8093 Zurich, Switzerland
    Biomaterials 30:3058-67. 2009
    ..Our studies demonstrate the versatility of SF as a biomaterial to engineer modified fibrous scaffolds and underscore the use of biofunctionally relevant analytical assays to optimize fibrous biomaterial scaffolds...
  5. ncbi request reprint Silk fibroin as an organic polymer for controlled drug delivery
    S Hofmann
    Drug Formulation and Delivery, ETH Zurich, 8093 Zurich, Switzerland
    J Control Release 111:219-27. 2006
    ....
  6. ncbi request reprint Stabilizing insulin-like growth factor-I in poly(D,L-lactide-co-glycolide) microspheres
    L Meinel
    Department of Applied BioSciences, Galenical Pharmacy, ETH Zurich, Winterthurer Strasse 190, 8057 Zurich, Switzerland
    J Control Release 70:193-202. 2001
    ..In conclusion, the developed microspheres proved to be suitable to release biologically intact IGF-I over up to 13 days, a time-period considered to be relevant to promote bone fracture healing...
  7. ncbi request reprint Bioreactor cultivation of osteochondral grafts
    G Vunjak-Novakovic
    Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Orthod Craniofac Res 8:209-18. 2005
    ..Taken together, these studies provide a basis for the ongoing work on engineering osreochondral grafts for a variety of potential applications, including those in the craniofacial complex...
  8. pmc BMP-silk composite matrices heal critically sized femoral defects
    C Kirker-Head
    Tufts Cummings School of Veterinary Medicine, North Grafton, MA, USA
    Bone 41:247-55. 2007
    ..These data imply the clinical potential of silk scaffolds and rhBMP-2 as composite osteopromotive implants when used alone or with select stem cell populations. Additional studies in larger species are now warranted...