Research Topics
| Brigitte M KudielkaSummaryAffiliation: Swiss Federal Institute of Technology Country: Switzerland Publications
| Collaborators
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Detail Information
Publications
Differential heart rate reactivity and recovery after psychosocial stress (TSST) in healthy children, younger adults, and elderly adults: the impact of age and genderBrigitte M Kudielka
Department of Behavioral Sciences, Swiss Federal Institute of Technology, CH 8092 Zurich, Switzerland
Int J Behav Med 11:116-21. 2004..In sum, this reanalysis revealed differential heart rate responses and recovery after exposition to the TSST in healthy children, younger adults, and elderly adults...- The interrelationship of psychosocial risk factors for coronary artery disease in a working population: do we measure distinct or overlapping psychological concepts?Brigitte M Kudielka
Institute for Behavioral Sciences, Swiss Federal Institute of Technology ETH, Zurich, Switzerland
Behav Med 30:35-43. 2004..This strengthens the assumption that the psychometric scales used constitute distinct psychological concepts, in particular, depressive symptomatology and negative affectivity versus vital exhaustion... - Acute HPA axis responses, heart rate, and mood changes to psychosocial stress (TSST) in humans at different times of dayBrigitte M Kudielka
Department of Behavioral Sciences, Swiss Federal Institute of Technology ETH, Turnerstr 1, CH 8092 Zurich, Switzerland
Psychoneuroendocrinology 29:983-92. 2004..We conclude that comparable HPA axis and heart rate stress responses to psychosocial stress can be measured in the morning and afternoon... - The effect of repeated acute mental stress on habituation and recovery responses in hemoconcentration and blood cells in healthy menKatharina Mischler
Institute for Behavioral Sciences, Federal Institute of Technology, Zurich, Switzerland
Life Sci 77:1166-79. 2005..Plasma volume shift accompanying stress affects the time course of stress polycytosis... - Overcommitment to work is associated with vital exhaustionDaniel Preckel
Swiss Federal Institute of Technology (ETH, Institute for Behavioral Sciences, Turnerstrasse 1, 8092 Zurich, Switzerland
Int Arch Occup Environ Health 78:117-22. 2005..It appears to be an important personality trait that may contribute to feelings of exhaustion at times of increased job strain... - Relationship between overnight neuroendocrine activity and morning haemostasis in working menRoland von Kanel
Institute for Behavioral Sciences, Federal Institute of Technology, Zurich, Switzerland
Clin Sci (Lond) 107:89-95. 2004..Although overnight SNS hyperactivity was associated independently with morning hypercoagulability, the relationship between the activity of HPAA and haemostasis was mediated by traditional cardiovascular risk factors... - Hypercoagulability in working men and women with high levels of panic-like anxietyRoland von Kanel
Institute for Behavioral Sciences, Swiss Federal Institute of Technology, Zurich, Switzerland
Psychother Psychosom 73:353-60. 2004..An increased clotting diathesis might subject anxious individuals to an elevated arterial thrombotic risk. We investigated whether panic-like anxiety would relate to a hypercoagulable state... - Relationship between hemoconcentration and blood coagulation responses to acute mental stressLilian Zgraggen
Institute for Behavioral Sciences, Federal Institute of Technology, Zurich, Switzerland
Thromb Res 115:175-83. 2005..However, stress hemoconcentration appears not to explain a substantial proportion in coagulation changes elicited by acute mental stress... - Circadian cortisol profiles and psychological self-reports in shift workers with and without recent change in the shift rotation systemBrigitte M Kudielka
Department of Theoretical and Clinical Psychobiology, University of Trier, Johanniterufer 15, D 54290 Trier, Germany
Biol Psychol 74:92-103. 2007..Results of a psychological assessment including exhaustion, chronic stress, effort-reward imbalance, and ratings of sleep quality and sleep length are also presented... 
Day-to-day dynamics of experience--cortisol associations in a population-based sample of older adultsEmma K Adam
School of Education and Social Policy and Cells to Society Center, Institute for Policy Research, Northwestern University, Evanston, IL 60208, USA
Proc Natl Acad Sci U S A 103:17058-63. 2006..Results are consistent with a dynamic and transactional function of cortisol as both a transducer of psychosocial and emotional experience into physiological activation and an influence on feelings of energy and physical well-being...- Parity does not alter baseline or stimulated activity of the hypothalamus-pituitary-adrenal axis in womenIlona S Federenko
Department of Psychology and Social Behavior, University of California, Irvine, 3340 Social Ecology II, Irvine, CA 92697 7085, USA
Dev Psychobiol 48:703-11. 2006.... - Age and sex steroid-related changes in glucocorticoid sensitivity of pro-inflammatory cytokine production after psychosocial stressNicolas Rohleder
Center for Psychobiological and Psychosomatic Research, University of Trier, Germany
J Neuroimmunol 126:69-77. 2002.... - Is the cortisol awakening rise a response to awakening?Ines Wilhelm
Department of Psychobiology, University of Trier, Johanniterufer 15, 54290 Trier, Germany
Psychoneuroendocrinology 32:358-66. 2007..Although the cortisol awakening response is modulated by circadian influences, it primarily reflects phasic psychophysiological processes specific to the sleep-wake transition... - Further support for higher salivary cortisol levels in "morning" compared to "evening" personsBrigitte M Kudielka
Department of Theoretical and Clinical Psychobiology, University of Trier, Trier, Germany
J Psychosom Res 62:595-6. 2007..04). In sum, the present data seem to corroborate the idea of higher daytime cortisol levels in morning relative to evening types in a sample of healthy middle-aged male and female adults... - Compliance with ambulatory saliva sampling in the chicago health, aging, and social relations study and associations with social supportBrigitte M Kudielka
Graduate School of Psychobiology, University of Trier, Trier, Germany
Ann Behav Med 34:209-16. 2007..Noncompliance with instructed saliva sampling times in ambulatory settings can compromise resulting cortisol findings... 
Cortisol dysregulation in school teachers in relation to burnout, vital exhaustion, and effort-reward-imbalanceSilja Bellingrath
Department of Theoretical and Clinical Psychobiology, Graduate School of Psychobiology, University of Trier, Johanniterufer 15, D 54290 Trier, Germany
Biol Psychol 78:104-13. 2008....- Circulating fibrinogen but not D-dimer level is associated with vital exhaustion in school teachersBrigitte M Kudielka
Department of Theoretical and Clinical Psychobiology, Graduate School of Psychobiology, University of Trier, Trier, Germany
Stress 11:250-8. 2008..Elevated fibrinogen might be one biological pathway by which chronic work stress may impact on teachers' cardiovascular health in the long run... - Health-related quality of life measured by the SF12 in working populations: associations with psychosocial work characteristicsBrigitte M Kudielka
Department of Clinical and Theoretical Psychobiology, University of Trier, Trier, Germany
J Occup Health Psychol 10:429-40. 2005..Psychosocial work characteristics account for relevant proportions in the subjective perception of mental health beyond a wide array of medical variables and personality factors... - Morningness and eveningness: the free cortisol rise after awakening in "early birds" and "night owls"Brigitte M Kudielka
Department of Clinical and Theoretical Psychobiology, University of Trier, Johanniterufer 15, D 54290 Trier, Germany
Biol Psychol 72:141-6. 2006..In sum, individual chronotype should be acknowledged as one further possible source of interindividual variability in the cortisol rise after awakening... - Exhaustion is associated with reduced habituation of free cortisol responses to repeated acute psychosocial stressBrigitte M Kudielka
Department of Clinical and Theoretical Psychobiology, University of Trier, Johanniterufer 15, D 54290 Trier, Germany
Biol Psychol 72:147-53. 2006..Absence of normal habituation might be one potential mechanism how exhaustion relates to increased disease vulnerability... - Compliance with saliva sampling protocols: electronic monitoring reveals invalid cortisol daytime profiles in noncompliant subjectsBrigitte M Kudielka
Department of Experimental Psychology II, , Germany
Psychosom Med 65:313-9. 2003..We therefore recommend the use of electronic monitoring devices or other suitable methods and that study participants be informed about the device when ambulatory saliva collection is performed... - Stress, health and ageing: a focus on postmenopausal womenOliver T Wolf
Department of Cognitive Psychology, Ruhr University Bochum, Universitatsstrasse 150, D 44780 Bochum, Germany
Menopause Int 14:129-33. 2008..At the end, the concept of allostatic load (AL) is described, which aims at a broader assessment of the impact of stress on the individual. The strengths and also the current limitations of the AL concept are highlighted... - The effect of natural habituation on coagulation responses to acute mental stress and recovery in menRoland von Kanel
Department of General Internal Medicine Division of Psychosomatic Medicine, University Hospital Inselspital, CH 3010 Berne, Switzerland
Thromb Haemost 92:1327-35. 2004..An incapacity of the coagulation system to adapt to stress repeats is perhaps a consequence of evolution, but might also contribute to increased coronary risk in some individuals, particularly in those with cardiovascular diseases... - Sex differences in HPA axis responses to stress: a reviewBrigitte M Kudielka
Department of Clinical and Theoretical Psychobiology, University of Trier, Johanniterufer 15, D-54290 Trier, Germany
Biol Psychol 69:113-32. 2005 - Different contribution of interleukin-6 and cortisol activity to total plasma fibrin concentration and to acute mental stress-induced fibrin formationRoland von Kanel
Department of General Internal Medicine, Division of Psychosomatic Medicine, University Hospital, CH 3010 Berne, Switzerland
Clin Sci (Lond) 109:61-7. 2005..Pro-inflammatory and procoagulant changes with stress were associated. Aside from fibrinogen reactivity, IL-6 reactivity was an independent predictor of stress-induced fibrin formation... - Opposite effect of negative and positive affect on stress procoagulant reactivityRoland von Kanel
Department of General Internal Medicine, Division of Psychosomatic Medicine, University Hospital Berne, Switzerland
Physiol Behav 86:61-8. 2005..Negative affect was associated with attenuated procoagulant reactivity to stress and the opposite was observed for positive affect. Negative affect is not likely to enhance the acute procoagulant stress response in healthy men... - Delayed response and lack of habituation in plasma interleukin-6 to acute mental stress in menRoland von Kanel
Department of General Internal Medicine, Division of Psychosomatic Medicine, University Hospital Berne, Switzerland
Brain Behav Immun 20:40-8. 2006..The hypothalamus-pituitary-adrenal axis may attenuate stress reactivity of IL-6. The lack of habituation in IL-6 responses to daily stress could subject at-risk individuals to higher atherosclerotic morbidity and mortality... - Association between burnout and circulating levels of pro- and anti-inflammatory cytokines in schoolteachersRoland von Kanel
Division of Psychosomatic Medicine, Inselspital, Bern University Hospital and University of Bern, Switzerland
J Psychosom Res 65:51-9. 2008..Knowing that a chronic low-grade systemic inflammatory state contributes to atherosclerosis, we investigated circulating cytokine levels in relation to burnout symptoms... - The effects of aspirin and nonselective beta blockade on the acute prothrombotic response to psychosocial stress in apparently healthy subjectsRoland von Kanel
Department of General Internal Medicine, University Hospital Berne, Switzerland
J Cardiovasc Pharmacol 51:231-8. 2008..This suggests that these cardiovascular drugs might exert limited protection from the development of stress-triggered coronary thrombosis... - Cortisol day profiles in victims of mobbing (bullying at the work place): preliminary results of a first psychobiological field studyBrigitte M Kudielka
J Psychosom Res 56:149-50. 2004 - No effect of 5-day treatment with acetylsalicylic acid (aspirin) or the beta-blocker propranolol (Inderal) on free cortisol responses to acute psychosocial stress: a randomized double-blind, placebo-controlled studyBrigitte M Kudielka
Department of Theoretical and Clinical Psychobiology, Graduate School of Psychobiology, University of Trier, Trier, Germany
Neuropsychobiology 56:159-66. 2007.... - Effects of aspirin and propranolol on the acute psychological stress response in factor VIII coagulant activity: a randomized, double-blind, placebo-controlled experimental studyRoland von Kanel
Department of General Internal Medicine, Swiss Cardiovascular Center, University Hospital Berne, Berne, Switzerland
Blood Coagul Fibrinolysis 19:75-81. 2008..The effect of single aspirin on the acute clotting factor VIII stress response was indistinguishable from a placebo effect... - Aspirin, but not propranolol, attenuates the acute stress-induced increase in circulating levels of interleukin-6: a randomized, double-blind, placebo-controlled studyRoland von Kanel
Department of General Internal Medicine, University Hospital Bern, CH 3010 Bern, Switzerland
Brain Behav Immun 22:150-7. 2008..Aspirin but not propranolol attenuated the stress-induced increase in plasma IL-6 levels. This suggests one mechanism by which aspirin treatment might reduce the risk of atherothrombotic events triggered by acute mental stress... - Relation of morning serum cortisol to prothrombotic activity in women with stable coronary artery diseaseRoland von Kanel
Department of General Internal Medicine, University Hospital, Berne 3010, Switzerland
J Thromb Thrombolysis 25:165-72. 2008..We hypothesized a direct relationship between cortisol and hemostasis factors related to a prothrombotic state in coronary artery disease... - Salivary cortisol sampling compliance: comparison of patients and healthy volunteersJoan E Broderick
Department of Psychiatry and Behavioral Science, Putnam Hall, Stony Brook University, Stony Brook, NY 11794 8790, USA
Psychoneuroendocrinology 29:636-50. 2004..This study investigated compliance with salivary cortisol sampling in a 7-day protocol. Impact of non-compliance on cortisol data was evaluated...