Harald F Krug

Summary

Affiliation: Swiss Federal Laboratories for Materials Testing and Research
Country: Switzerland

Publications

  1. ncbi request reprint Nanosafety research--are we on the right track?
    Harald F Krug
    International Reserach Cooperations Manager, Empa, Lerchenfeldstrasse 5, St Gallen, 9014 Switzerland
    Angew Chem Int Ed Engl 53:12304-19. 2014
  2. pmc Caspase-10 is the key initiator caspase involved in tributyltin-mediated apoptosis in human immune cells
    Harald F Krug
    Department Materials Meet Life, Empa Swiss Federal Laboratories for Materials Science and Technology, Lerchenfeldstrasse 5, 9014 St Gallen, Switzerland
    J Toxicol 2012:395482. 2012
  3. pmc Pulmonary surfactant coating of multi-walled carbon nanotubes (MWCNTs) influences their oxidative and pro-inflammatory potential in vitro
    Michael Gasser
    Adolphe Merkle Institute, University of Fribourg, Marly, Switzerland
    Part Fibre Toxicol 9:17. 2012
  4. ncbi request reprint Nanotoxicology: an interdisciplinary challenge
    Harald F Krug
    EMPA Materials Science and Technology, Department Materials Meet Life, St Gallen, Switzerland
    Angew Chem Int Ed Engl 50:1260-78. 2011
  5. pmc Comparability of in vitro tests for bioactive nanoparticles: a common assay to detect reactive oxygen species as an example
    Matthias Roesslein
    Empa, Materials Biology Interactions Laboratory, Swiss Federal Laboratories for Materials Science and Technology, Lerchenfeldstrasse 5, CH 9014 St Gallen, Switzerland
    Int J Mol Sci 14:24320-37. 2013
  6. ncbi request reprint A comparison of acute and long-term effects of industrial multiwalled carbon nanotubes on human lung and immune cells in vitro
    Tina Thurnherr
    Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Materials Biology Interactions, Lerchenfeldstrasse 5, 9014 St Gallen, Switzerland
    Toxicol Lett 200:176-86. 2011
  7. ncbi request reprint In vitro mechanistic study towards a better understanding of ZnO nanoparticle toxicity
    Tina Buerki-Thurnherr
    Empa, Swiss Federal Laboratories for Materials Testing and Technology, Laboratory for Materials Biology Interactions, Lerchenfeldstrasse, St Gallen, Switzerland
    Nanotoxicology 7:402-16. 2013
  8. ncbi request reprint Toward the development of decision supporting tools that can be used for safe production and use of nanomaterials
    Claudia Som
    Empa, Swiss Laboratory for Materials Science and Technology, Lerchenfeldstrasse 5, 9014 St Gallen, Switzerland
    Acc Chem Res 46:863-72. 2013
  9. ncbi request reprint Nanomaterial cell interactions: are current in vitro tests reliable?
    Cordula Hirsch
    Empa, Swiss Federal Laboratories for Materials Research and Testing, Laboratory for Materials Biology Interactions, Lerchenfeldstrasse 5, St Gallen, Switzerland
    Nanomedicine (Lond) 6:837-47. 2011
  10. pmc The adsorption of biomolecules to multi-walled carbon nanotubes is influenced by both pulmonary surfactant lipids and surface chemistry
    Michael Gasser
    Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Materials Biology Interactions, St, Gallen, Switzerland
    J Nanobiotechnology 8:31. 2010

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Nanosafety research--are we on the right track?
    Harald F Krug
    International Reserach Cooperations Manager, Empa, Lerchenfeldstrasse 5, St Gallen, 9014 Switzerland
    Angew Chem Int Ed Engl 53:12304-19. 2014
    ..Now, on the basis of a comprehensive review of the literature and with the help of selected toxicological end points, we attempt to indicate where the significant weaknesses of these studies lie and what we must improve in the future. ..
  2. pmc Caspase-10 is the key initiator caspase involved in tributyltin-mediated apoptosis in human immune cells
    Harald F Krug
    Department Materials Meet Life, Empa Swiss Federal Laboratories for Materials Science and Technology, Lerchenfeldstrasse 5, 9014 St Gallen, Switzerland
    J Toxicol 2012:395482. 2012
    ..We could show that caspase-10 is recruited by the TRAIL-R2 receptor and apoptosis is totally prevented when caspase-10 is specifically inhibited in all three cell lines...
  3. pmc Pulmonary surfactant coating of multi-walled carbon nanotubes (MWCNTs) influences their oxidative and pro-inflammatory potential in vitro
    Michael Gasser
    Adolphe Merkle Institute, University of Fribourg, Marly, Switzerland
    Part Fibre Toxicol 9:17. 2012
    ..The effect of MWCNTs surface charge was also investigated in terms of amino (-NH2) and carboxyl (-COOH) surface modifications...
  4. ncbi request reprint Nanotoxicology: an interdisciplinary challenge
    Harald F Krug
    EMPA Materials Science and Technology, Department Materials Meet Life, St Gallen, Switzerland
    Angew Chem Int Ed Engl 50:1260-78. 2011
    ..In particular, inadequate methods will be described together with recommendations how to avoid this in the future, thereby contributing to a sustainable improvement of the available data...
  5. pmc Comparability of in vitro tests for bioactive nanoparticles: a common assay to detect reactive oxygen species as an example
    Matthias Roesslein
    Empa, Materials Biology Interactions Laboratory, Swiss Federal Laboratories for Materials Science and Technology, Lerchenfeldstrasse 5, CH 9014 St Gallen, Switzerland
    Int J Mol Sci 14:24320-37. 2013
    ..However, a quantitative measurement of the absolute amount of ROS produced and a quantitative comparison between experiments is (at the moment) impossible. ..
  6. ncbi request reprint A comparison of acute and long-term effects of industrial multiwalled carbon nanotubes on human lung and immune cells in vitro
    Tina Thurnherr
    Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Materials Biology Interactions, Lerchenfeldstrasse 5, 9014 St Gallen, Switzerland
    Toxicol Lett 200:176-86. 2011
    ..Our study demonstrates that despite the high potential for ROS formation, pristine MWCNTs can accumulate and persist within cells without having major long-term consequences or inducing adaptive mechanisms...
  7. ncbi request reprint In vitro mechanistic study towards a better understanding of ZnO nanoparticle toxicity
    Tina Buerki-Thurnherr
    Empa, Swiss Federal Laboratories for Materials Testing and Technology, Laboratory for Materials Biology Interactions, Lerchenfeldstrasse, St Gallen, Switzerland
    Nanotoxicology 7:402-16. 2013
    ..In addition, we identified novel coating strategies to reduce ZnO NP dissolution and subsequent adverse effects...
  8. ncbi request reprint Toward the development of decision supporting tools that can be used for safe production and use of nanomaterials
    Claudia Som
    Empa, Swiss Laboratory for Materials Science and Technology, Lerchenfeldstrasse 5, 9014 St Gallen, Switzerland
    Acc Chem Res 46:863-72. 2013
    ....
  9. ncbi request reprint Nanomaterial cell interactions: are current in vitro tests reliable?
    Cordula Hirsch
    Empa, Swiss Federal Laboratories for Materials Research and Testing, Laboratory for Materials Biology Interactions, Lerchenfeldstrasse 5, St Gallen, Switzerland
    Nanomedicine (Lond) 6:837-47. 2011
    ..These recommendations consequently applied in the future will increase the safe and sustainable use of nanotechnology...
  10. pmc The adsorption of biomolecules to multi-walled carbon nanotubes is influenced by both pulmonary surfactant lipids and surface chemistry
    Michael Gasser
    Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Materials Biology Interactions, St, Gallen, Switzerland
    J Nanobiotechnology 8:31. 2010
    ..abstract:..
  11. ncbi request reprint 120 years of nanosilver history: implications for policy makers
    Bernd Nowack
    Empa Swiss Federal Laboratories for Materials Science and Technology, Lerchenfeldstrasse 5, CH 9014 St Gallen, Switzerland
    Environ Sci Technol 45:1177-83. 2011
    ....
  12. pmc Barrier capacity of human placenta for nanosized materials
    Peter Wick
    Empa, Swiss Federal Laboratories for Material Testing and Research, Laboratory for Materials Biology Interactions, St Gallen, Switzerland
    Environ Health Perspect 118:432-6. 2010
    ..Previous work has not addressed the question of whether nanoparticles may cross the placenta...