Frederik Graw

Summary

Affiliation: Swiss Federal Institute of Technology
Country: Switzerland

Publications

  1. doi On pseudo-values for regression analysis in competing risks models
    Frederik Graw
    Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland
    Lifetime Data Anal 15:241-55. 2009
  2. pmc Investigating CTL mediated killing with a 3D cellular automaton
    Frederik Graw
    Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland
    PLoS Comput Biol 5:e1000466. 2009
  3. pmc Theoretical analysis of the evolution of immune memory
    Frederik Graw
    Integrative Biology, ETH Zurich, Switzerland
    BMC Evol Biol 10:380. 2010
  4. pmc Influence of the fibroblastic reticular network on cell-cell interactions in lymphoid organs
    Frederik Graw
    Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland
    PLoS Comput Biol 8:e1002436. 2012
  5. ncbi CD8+ T Cells Are Activated in an Antigen-Independent Manner in HIV-Infected Individuals
    Sonia Bastidas
    Institute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland
    J Immunol 192:1732-44. 2014
  6. pmc Comparison of cytotoxic T lymphocyte efficacy in acute and persistent lymphocytic choriomeningitis virus infection
    Frederik Graw
    Institute of Integrative Biology, ETH Zurich, Universitatstrasse 16, 8092 Zurich, Switzerland
    Proc Biol Sci 278:3395-402. 2011

Collaborators

Detail Information

Publications6

  1. doi On pseudo-values for regression analysis in competing risks models
    Frederik Graw
    Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland
    Lifetime Data Anal 15:241-55. 2009
    ..In the application we consider for comparison the estimates obtained with the Fine and Gray approach (J Am Stat Assoc 94:496-509, 1999) and also time-dependent solutions of pseudo-value regression equations...
  2. pmc Investigating CTL mediated killing with a 3D cellular automaton
    Frederik Graw
    Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland
    PLoS Comput Biol 5:e1000466. 2009
    ..Our analysis identifies additional experimental directions which are of particular importance to interpret estimates of killing rates and could advance our quantitative understanding of CTL killing...
  3. pmc Theoretical analysis of the evolution of immune memory
    Frederik Graw
    Integrative Biology, ETH Zurich, Switzerland
    BMC Evol Biol 10:380. 2010
    ..Is there a limit to how many memory cells a host can generate and maintain? If there is a limit, how should new cells be incorporated into a filled memory compartment? And how many different pathogens should the immune system remember?..
  4. pmc Influence of the fibroblastic reticular network on cell-cell interactions in lymphoid organs
    Frederik Graw
    Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland
    PLoS Comput Biol 8:e1002436. 2012
    ..We propose alternative hypotheses by which the FRC network might influence the functionality of immune responses in a more significant way...
  5. ncbi CD8+ T Cells Are Activated in an Antigen-Independent Manner in HIV-Infected Individuals
    Sonia Bastidas
    Institute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland
    J Immunol 192:1732-44. 2014
    ..These observations explain the higher abundance of activated CD8(+) T cells compared with CD4(+) T cells in untreated HIV-1 infection. ..
  6. pmc Comparison of cytotoxic T lymphocyte efficacy in acute and persistent lymphocytic choriomeningitis virus infection
    Frederik Graw
    Institute of Integrative Biology, ETH Zurich, Universitatstrasse 16, 8092 Zurich, Switzerland
    Proc Biol Sci 278:3395-402. 2011
    ..These results strongly suggest that the in vivo cytotoxicity of CD8(+) T-cell responses in persistent infection is modulated via the number of CTLs rather than their individual functionality...