Andre P Gerber

Summary

Affiliation: Swiss Federal Institute of Technology
Country: Switzerland

Publications

  1. ncbi Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system
    Alessia Galgano
    Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    PLoS ONE 3:e3164. 2008
  2. ncbi Post-transcriptional gene regulation: from genome-wide studies to principles
    R E Halbeisen
    Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    Cell Mol Life Sci 65:798-813. 2008
  3. ncbi Genome-wide identification of mRNAs associated with the translational regulator PUMILIO in Drosophila melanogaster
    Andre P Gerber
    Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland
    Proc Natl Acad Sci U S A 103:4487-92. 2006
  4. ncbi A screen for RNA-binding proteins in yeast indicates dual functions for many enzymes
    Tanja Scherrer
    Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    PLoS ONE 5:e15499. 2010
  5. ncbi Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins
    Tanja Scherrer
    Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Wolfgang Pauli Strasse 10, 8093 Zurich, Switzerland
    Genome Biol 12:R3. 2011
  6. ncbi Cotranslational assembly of the yeast SET1C histone methyltransferase complex
    Andre Halbach
    Institute of Molecular Biology, University of Zurich, Zurich, Switzerland
    EMBO J 28:2959-70. 2009
  7. ncbi La-motif-dependent mRNA association with Slf1 promotes copper detoxification in yeast
    Luca Schenk
    Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, 8093 Zurich, Switzerland
    RNA 18:449-61. 2012
  8. ncbi Circuitry of mRNA regulation
    Alexander Kanitz
    Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland
    Wiley Interdiscip Rev Syst Biol Med 2:245-51. 2010
  9. ncbi RNA-binding protein immunopurification-microarray (RIP-Chip) analysis to profile localized RNAs
    Alessia Galgano
    Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    Methods Mol Biol 714:369-85. 2011
  10. ncbi The expression levels of microRNA-361-5p and its target VEGFA are inversely correlated in human cutaneous squamous cell carcinoma
    Alexander Kanitz
    Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    PLoS ONE 7:e49568. 2012

Collaborators

Detail Information

Publications13

  1. ncbi Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system
    Alessia Galgano
    Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    PLoS ONE 3:e3164. 2008
    ..Our work suggests extensive connections between the RBP and miRNA post-transcriptional regulatory systems and provides a framework for deciphering the molecular mechanism by which PUF proteins regulate their target mRNAs...
  2. ncbi Post-transcriptional gene regulation: from genome-wide studies to principles
    R E Halbeisen
    Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    Cell Mol Life Sci 65:798-813. 2008
    ..It will be a future challenge to link the spectra of targets for RNA-binding proteins to post-transcriptional regulatory programs and to reveal its physiological implications...
  3. ncbi Genome-wide identification of mRNAs associated with the translational regulator PUMILIO in Drosophila melanogaster
    Andre P Gerber
    Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland
    Proc Natl Acad Sci U S A 103:4487-92. 2006
    ..The results suggest extensive posttranscriptional regulation by PUMILIO and uncover evolutionary features of this conserved family of RNA-binding proteins...
  4. ncbi A screen for RNA-binding proteins in yeast indicates dual functions for many enzymes
    Tanja Scherrer
    Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    PLoS ONE 5:e15499. 2010
    ..Our results suggest that many proteins may associate with mRNAs and possibly control their fates, providing dense connections between different layers of cellular regulation...
  5. ncbi Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins
    Tanja Scherrer
    Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Wolfgang Pauli Strasse 10, 8093 Zurich, Switzerland
    Genome Biol 12:R3. 2011
    ..To explore the impact of these proteins on RNA regulation, we undertook a systematic analysis of the RNA targets and of the global implications for gene expression...
  6. ncbi Cotranslational assembly of the yeast SET1C histone methyltransferase complex
    Andre Halbach
    Institute of Molecular Biology, University of Zurich, Zurich, Switzerland
    EMBO J 28:2959-70. 2009
    ....
  7. ncbi La-motif-dependent mRNA association with Slf1 promotes copper detoxification in yeast
    Luca Schenk
    Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, 8093 Zurich, Switzerland
    RNA 18:449-61. 2012
    ..These results provide the first evidence for post-transcriptional regulation of factors/pathways implicated in copper homeostasis by a cytoplasmic RBP...
  8. ncbi Circuitry of mRNA regulation
    Alexander Kanitz
    Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland
    Wiley Interdiscip Rev Syst Biol Med 2:245-51. 2010
    ..All gene regulatory systems are composed of simple network circuits that coordinate the transfer of regulatory signals to a target gene/message...
  9. ncbi RNA-binding protein immunopurification-microarray (RIP-Chip) analysis to profile localized RNAs
    Alessia Galgano
    Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    Methods Mol Biol 714:369-85. 2011
    ....
  10. ncbi The expression levels of microRNA-361-5p and its target VEGFA are inversely correlated in human cutaneous squamous cell carcinoma
    Alexander Kanitz
    Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    PLoS ONE 7:e49568. 2012
    ..Importantly, we found that miR-361-5p levels are inversely correlated with VEGFA expression in SCC and in healthy skin, indicating that miR-361-5p could play a role in cancers...
  11. ncbi Stress-dependent coordination of transcriptome and translatome in yeast
    Regula E Halbeisen
    Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland
    PLoS Biol 7:e1000105. 2009
    ..These networks are preferentially activated for rapid adaptation of cells to minor environmental perturbations...
  12. ncbi Affinity purification of ribosomes to access the translatome
    Regula E Halbeisen
    Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Wolfgang Pauli Strasse 10, CH 8093 Zurich, Switzerland
    Methods 48:306-10. 2009
    ..Finally, application of this method in other organisms provides a valuable tool to decipher cell-type specific gene expression patterns...
  13. ncbi MicroRNA-96 directly inhibits γ-globin expression in human erythropoiesis
    Imane Azzouzi
    Division of Haematology, University Children s Hospital, Zurich, Switzerland
    PLoS ONE 6:e22838. 2011
    ..Based on these results we conclude that microRNA-96 directly suppresses γ-globin expression and thus contributes to HbF regulation...