Andre P Gerber

Summary

Affiliation: Swiss Federal Institute of Technology
Country: Switzerland

Publications

  1. pmc Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system
    Alessia Galgano
    Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    PLoS ONE 3:e3164. 2008
  2. pmc A screen for RNA-binding proteins in yeast indicates dual functions for many enzymes
    Tanja Scherrer
    Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    PLoS ONE 5:e15499. 2010
  3. pmc Post-transcriptional gene regulation: from genome-wide studies to principles
    R E Halbeisen
    Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    Cell Mol Life Sci 65:798-813. 2008
  4. pmc Genome-wide identification of mRNAs associated with the translational regulator PUMILIO in Drosophila melanogaster
    Andre P Gerber
    Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland
    Proc Natl Acad Sci U S A 103:4487-92. 2006
  5. pmc Stress-dependent coordination of transcriptome and translatome in yeast
    Regula E Halbeisen
    Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland
    PLoS Biol 7:e1000105. 2009
  6. pmc RIP-chip-SRM--a new combinatorial large-scale approach identifies a set of translationally regulated bantam/miR-58 targets in C. elegans
    Marko Jovanovic
    Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland
    Genome Res 22:1360-71. 2012
  7. pmc Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins
    Tanja Scherrer
    Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Wolfgang Pauli Strasse 10, 8093 Zurich, Switzerland
    Genome Biol 12:R3. 2011
  8. pmc Cotranslational assembly of the yeast SET1C histone methyltransferase complex
    Andre Halbach
    Institute of Molecular Biology, University of Zurich, Zurich, Switzerland
    EMBO J 28:2959-70. 2009
  9. doi request reprint Affinity purification of ribosomes to access the translatome
    Regula E Halbeisen
    Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Wolfgang Pauli Strasse 10, CH 8093 Zurich, Switzerland
    Methods 48:306-10. 2009
  10. doi request reprint RNA-binding protein immunopurification-microarray (RIP-Chip) analysis to profile localized RNAs
    Alessia Galgano
    Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    Methods Mol Biol 714:369-85. 2011

Collaborators

Detail Information

Publications15

  1. pmc Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system
    Alessia Galgano
    Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    PLoS ONE 3:e3164. 2008
    ..Our work suggests extensive connections between the RBP and miRNA post-transcriptional regulatory systems and provides a framework for deciphering the molecular mechanism by which PUF proteins regulate their target mRNAs...
  2. pmc A screen for RNA-binding proteins in yeast indicates dual functions for many enzymes
    Tanja Scherrer
    Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    PLoS ONE 5:e15499. 2010
    ..Our results suggest that many proteins may associate with mRNAs and possibly control their fates, providing dense connections between different layers of cellular regulation...
  3. pmc Post-transcriptional gene regulation: from genome-wide studies to principles
    R E Halbeisen
    Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    Cell Mol Life Sci 65:798-813. 2008
    ..It will be a future challenge to link the spectra of targets for RNA-binding proteins to post-transcriptional regulatory programs and to reveal its physiological implications...
  4. pmc Genome-wide identification of mRNAs associated with the translational regulator PUMILIO in Drosophila melanogaster
    Andre P Gerber
    Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland
    Proc Natl Acad Sci U S A 103:4487-92. 2006
    ..The results suggest extensive posttranscriptional regulation by PUMILIO and uncover evolutionary features of this conserved family of RNA-binding proteins...
  5. pmc Stress-dependent coordination of transcriptome and translatome in yeast
    Regula E Halbeisen
    Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland
    PLoS Biol 7:e1000105. 2009
    ..These networks are preferentially activated for rapid adaptation of cells to minor environmental perturbations...
  6. pmc RIP-chip-SRM--a new combinatorial large-scale approach identifies a set of translationally regulated bantam/miR-58 targets in C. elegans
    Marko Jovanovic
    Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland
    Genome Res 22:1360-71. 2012
    ..Comparison of total mRNA and protein abundance changes in mir-58 mutant and wild-type animals indicated that the direct bantam/miR-58 targets identified here are mainly regulated at the level of protein abundance, not mRNA stability...
  7. pmc Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins
    Tanja Scherrer
    Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Wolfgang Pauli Strasse 10, 8093 Zurich, Switzerland
    Genome Biol 12:R3. 2011
    ..To explore the impact of these proteins on RNA regulation, we undertook a systematic analysis of the RNA targets and of the global implications for gene expression...
  8. pmc Cotranslational assembly of the yeast SET1C histone methyltransferase complex
    Andre Halbach
    Institute of Molecular Biology, University of Zurich, Zurich, Switzerland
    EMBO J 28:2959-70. 2009
    ....
  9. doi request reprint Affinity purification of ribosomes to access the translatome
    Regula E Halbeisen
    Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Wolfgang Pauli Strasse 10, CH 8093 Zurich, Switzerland
    Methods 48:306-10. 2009
    ..Finally, application of this method in other organisms provides a valuable tool to decipher cell-type specific gene expression patterns...
  10. doi request reprint RNA-binding protein immunopurification-microarray (RIP-Chip) analysis to profile localized RNAs
    Alessia Galgano
    Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    Methods Mol Biol 714:369-85. 2011
    ....
  11. pmc The expression levels of microRNA-361-5p and its target VEGFA are inversely correlated in human cutaneous squamous cell carcinoma
    Alexander Kanitz
    Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland
    PLoS ONE 7:e49568. 2012
    ..Importantly, we found that miR-361-5p levels are inversely correlated with VEGFA expression in SCC and in healthy skin, indicating that miR-361-5p could play a role in cancers...
  12. pmc Systematic screens of proteins binding to synthetic microRNA precursors
    Harry Towbin
    Institute of Pharmaceutical Sciences, ETH Zurich, CH 8093 Zurich, Switzerland
    Nucleic Acids Res 41:e47. 2013
    ....
  13. pmc La-motif-dependent mRNA association with Slf1 promotes copper detoxification in yeast
    Luca Schenk
    Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zurich, 8093 Zurich, Switzerland
    RNA 18:449-61. 2012
    ..These results provide the first evidence for post-transcriptional regulation of factors/pathways implicated in copper homeostasis by a cytoplasmic RBP...
  14. doi request reprint Circuitry of mRNA regulation
    Alexander Kanitz
    Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland
    Wiley Interdiscip Rev Syst Biol Med 2:245-51. 2010
    ..All gene regulatory systems are composed of simple network circuits that coordinate the transfer of regulatory signals to a target gene/message...
  15. pmc MicroRNA-96 directly inhibits γ-globin expression in human erythropoiesis
    Imane Azzouzi
    Division of Haematology, University Children s Hospital, Zurich, Switzerland
    PLoS ONE 6:e22838. 2011
    ..Based on these results we conclude that microRNA-96 directly suppresses γ-globin expression and thus contributes to HbF regulation...