Thomas J Fuchs

Summary

Affiliation: Swiss Federal Institute of Technology
Country: Switzerland

Publications

  1. pmc Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer
    Jürgen Veeck
    Molecular Oncology Group, Institute of Pathology, University Hospital of the RWTH Aachen, Pauwelsstrasse 30, D 52074 Aachen, Germany
    BMC Cancer 9:217. 2009
  2. pmc Nuclear detection of Y-box protein-1 (YB-1) closely associates with progesterone receptor negativity and is a strong adverse survival factor in human breast cancer
    Edgar Dahl
    Molecular Oncology Group, Institute of Pathology, Medical Faculty, RWTH Aachen University, Aachen, Germany
    BMC Cancer 9:410. 2009
  3. pmc Infinite mixture-of-experts model for sparse survival regression with application to breast cancer
    Sudhir Raman
    Department of Computer Science, University of Basel, Bernoullistr, 16, CH 4056 Basel, Switzerland
    BMC Bioinformatics 11:S8. 2010
  4. ncbi Computational pathology analysis of tissue microarrays predicts survival of renal clear cell carcinoma patients
    Thomas J Fuchs
    Institute for Computational Science, ETH Zurich, Switzerland
    Med Image Comput Comput Assist Interv 11:1-8. 2008
  5. ncbi Geometrical consistent 3D tracing of neuronal processes in ssTEM data
    Verena Kaynig
    Department of Computer Science, ETH Zurich, Switzerland
    Med Image Comput Comput Assist Interv 13:209-16. 2010
  6. doi Computational pathology: challenges and promises for tissue analysis
    Thomas J Fuchs
    Department of Computer Science, ETH Zurich, Universitaetstrasse 6, CH 8092 Zurich, Switzerland
    Comput Med Imaging Graph 35:515-30. 2011
  7. ncbi Graph-based pancreatic islet segmentation for early type 2 diabetes mellitus on histopathological tissue
    Xenofon Floros
    Department of Computer Science, ETH Zurich, Switzerland
    Med Image Comput Comput Assist Interv 12:633-40. 2009
  8. pmc TMARKER: A free software toolkit for histopathological cell counting and staining estimation
    Peter J Schüffler
    Institute for Computational Science, ETH Zurich, Switzerland Competence Center for Systems Physiology and Metabolic Diseases, ETH Zurich, Switzerland
    J Pathol Inform 4:S2. 2013

Collaborators

  • Joachim M Buhmann
  • Xenofon Floros
  • Verena Kaynig
  • Peter J Wild
  • Edgar Dahl
  • Peter J Schüffler
  • Sudhir Raman
  • Jürgen Veeck
  • Arndt Hartmann
  • Niels J Rupp
  • Cheng Soon Ong
  • Volker Roth
  • Abdelaziz En-Nia
  • Peter R Mertens
  • Elisabeth Breuer
  • Sonja Djudjaj
  • Renate Krings
  • Frank Wiesmann
  • Sandra E Dunn
  • Ruth Knüchel

Detail Information

Publications8

  1. pmc Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer
    Jürgen Veeck
    Molecular Oncology Group, Institute of Pathology, University Hospital of the RWTH Aachen, Pauwelsstrasse 30, D 52074 Aachen, Germany
    BMC Cancer 9:217. 2009
    ....
  2. pmc Nuclear detection of Y-box protein-1 (YB-1) closely associates with progesterone receptor negativity and is a strong adverse survival factor in human breast cancer
    Edgar Dahl
    Molecular Oncology Group, Institute of Pathology, Medical Faculty, RWTH Aachen University, Aachen, Germany
    BMC Cancer 9:410. 2009
    ..Given these predictive qualities of YB-1 detection we sought to establish a highly specific monoclonal antibody (Mab) for diagnostic testing and its characterization towards outcome prediction (relapse-free and overall survival)...
  3. pmc Infinite mixture-of-experts model for sparse survival regression with application to breast cancer
    Sudhir Raman
    Department of Computer Science, University of Basel, Bernoullistr, 16, CH 4056 Basel, Switzerland
    BMC Bioinformatics 11:S8. 2010
    ..The model is able to find key explanatory factors (chosen from main effects and higher-order interactions) for each sub-group by enforcing sparsity on the regression coefficients via the Bayesian Group-Lasso...
  4. ncbi Computational pathology analysis of tissue microarrays predicts survival of renal clear cell carcinoma patients
    Thomas J Fuchs
    Institute for Computational Science, ETH Zurich, Switzerland
    Med Image Comput Comput Assist Interv 11:1-8. 2008
    ..The application to a test set of 133 patients clearly demonstrates that our computational pathology analysis matches the prognostic performance of expert pathologists...
  5. ncbi Geometrical consistent 3D tracing of neuronal processes in ssTEM data
    Verena Kaynig
    Department of Computer Science, ETH Zurich, Switzerland
    Med Image Comput Comput Assist Interv 13:209-16. 2010
    ..Our experiments demonstrate significant improvement over grouping by Euclidean distance, reducing the split and merge error per object by a factor of two...
  6. doi Computational pathology: challenges and promises for tissue analysis
    Thomas J Fuchs
    Department of Computer Science, ETH Zurich, Universitaetstrasse 6, CH 8092 Zurich, Switzerland
    Comput Med Imaging Graph 35:515-30. 2011
    ..This paper reports on state-of-the-art of the design and effectiveness of computational pathology workflows and it discusses future research directions in this emergent field of medical informatics and diagnostic machine learning...
  7. ncbi Graph-based pancreatic islet segmentation for early type 2 diabetes mellitus on histopathological tissue
    Xenofon Floros
    Department of Computer Science, ETH Zurich, Switzerland
    Med Image Comput Comput Assist Interv 12:633-40. 2009
    ....
  8. pmc TMARKER: A free software toolkit for histopathological cell counting and staining estimation
    Peter J Schüffler
    Institute for Computational Science, ETH Zurich, Switzerland Competence Center for Systems Physiology and Metabolic Diseases, ETH Zurich, Switzerland
    J Pathol Inform 4:S2. 2013
    ..To facilitate reproducible analysis in clinical practice as well as for cancer research, objective computer assisted staining estimation is highly desirable...