S Alizon

Summary

Affiliation: Swiss Federal Institute of Technology
Country: Switzerland

Publications

  1. ncbi The Price equation framework to study disease within-host evolution
    S Alizon
    Institut für Integrative Biologie, ETH, Universitatstrasse 16, Zurich, Switzerland
    J Evol Biol 22:1123-32. 2009
  2. ncbi Virulence evolution and the trade-off hypothesis: history, current state of affairs and the future
    S Alizon
    Department of Mathematics and Statistics, Queen s University, Kingston, Canada
    J Evol Biol 22:245-59. 2009
  3. ncbi Acute or chronic? Within-host models with immune dynamics, infection outcome, and parasite evolution
    Samuel Alizon
    Ecole Normale Superieure, Unité Mixte de Recherche 7625 Fonctionnement et Evolution des Systèmes Ecologiques, Paris F 75005, France
    Am Nat 172:E244-56. 2008
  4. ncbi Multiple infections, immune dynamics, and the evolution of virulence
    Samuel Alizon
    Ecole Normale Superieure, Unité Mixte de Recherche 7625 Fonctionnement et Evolution des Systèmes Ecologiques, Paris F 75005, France
    Am Nat 172:E150-68. 2008
  5. ncbi Decreased overall virulence in coinfected hosts leads to the persistence of virulent parasites
    Samuel Alizon
    Department of Mathematics and Statistics, Queen s University, Jeffery Hall, Kingston, Ontario K7L 3N6, Canada
    Am Nat 172:E67-79. 2008
  6. ncbi Competition between cryptic species explains variations in rates of lineage evolution
    Samuel Alizon
    Department of Mathematics and Statistics, Jeffery Hall, Queen s University, Kingston, ON, Canada K7L 3N6
    Proc Natl Acad Sci U S A 105:12382-6. 2008
  7. ncbi Transmission-recovery trade-offs to study parasite evolution
    Samuel Alizon
    Department of Mathematics and Statistics, Queen s University, Kingston, Ontario K7L 3N6, Canada
    Am Nat 172:E113-21. 2008
  8. ncbi Linking within- and between-host dynamics in the evolutionary epidemiology of infectious diseases
    Nicole Mideo
    Department of Biology, Queen s University, Kingston, ON K7L 3N6, Canada
    Trends Ecol Evol 23:511-7. 2008
  9. ncbi Transmission-virulence trade-offs in vector-borne diseases
    Samuel Alizon
    Ecole Normale Superieure, UMR 7625 Fonctionnement et Evolution des Systèmes Ecologiques, Paris, F 75005, France
    Theor Popul Biol 74:6-15. 2008
  10. ncbi Emergence of a convex trade-off between transmission and virulence
    Samuel Alizon
    Laboratoire d Ecologie, Centre Nationale de la Recherche Scientifique Unité Mixte de Recherche CNRS UMR 7625, Ecole Normale Superieure, 75005 Paris, France
    Am Nat 165:E155-67. 2005

Detail Information

Publications10

  1. ncbi The Price equation framework to study disease within-host evolution
    S Alizon
    Institut für Integrative Biologie, ETH, Universitatstrasse 16, Zurich, Switzerland
    J Evol Biol 22:1123-32. 2009
    ..This framework can be used to address important biological issues, from immune escape to disease evolutionary response to treatments...
  2. ncbi Virulence evolution and the trade-off hypothesis: history, current state of affairs and the future
    S Alizon
    Department of Mathematics and Statistics, Queen s University, Kingston, Canada
    J Evol Biol 22:245-59. 2009
    ....
  3. ncbi Acute or chronic? Within-host models with immune dynamics, infection outcome, and parasite evolution
    Samuel Alizon
    Ecole Normale Superieure, Unité Mixte de Recherche 7625 Fonctionnement et Evolution des Systèmes Ecologiques, Paris F 75005, France
    Am Nat 172:E244-56. 2008
    ..g., predicting evolutionary consequences of new therapies and public health policies). We conclude by discussing new approaches based on embedded (or nested) models and identify future perspectives for the modeling of infectious diseases...
  4. ncbi Multiple infections, immune dynamics, and the evolution of virulence
    Samuel Alizon
    Ecole Normale Superieure, Unité Mixte de Recherche 7625 Fonctionnement et Evolution des Systèmes Ecologiques, Paris F 75005, France
    Am Nat 172:E150-68. 2008
    ..We interpret this result as a parasite specialization to the infectious state of the hosts. Our study has experimental and theoretical implications in a virulence management perspective...
  5. ncbi Decreased overall virulence in coinfected hosts leads to the persistence of virulent parasites
    Samuel Alizon
    Department of Mathematics and Statistics, Queen s University, Jeffery Hall, Kingston, Ontario K7L 3N6, Canada
    Am Nat 172:E67-79. 2008
    ..This model has theoretical and experimental implications: it underlines the importance of overall virulence and of epidemiological feedbacks on virulence evolution...
  6. ncbi Competition between cryptic species explains variations in rates of lineage evolution
    Samuel Alizon
    Department of Mathematics and Statistics, Jeffery Hall, Queen s University, Kingston, ON, Canada K7L 3N6
    Proc Natl Acad Sci U S A 105:12382-6. 2008
    ..This mechanism explains both the remarkable variation in apparent rates of evolution observed in marine plankton, as well as the presence of long gradual evolutionary trends...
  7. ncbi Transmission-recovery trade-offs to study parasite evolution
    Samuel Alizon
    Department of Mathematics and Statistics, Queen s University, Kingston, Ontario K7L 3N6, Canada
    Am Nat 172:E113-21. 2008
    ..Transmission-recovery trade-offs are of particular interest to the study of the evolution of human pathogens because of the use of antipathogen treatments, which strengthens the recovery constraint...
  8. ncbi Linking within- and between-host dynamics in the evolutionary epidemiology of infectious diseases
    Nicole Mideo
    Department of Biology, Queen s University, Kingston, ON K7L 3N6, Canada
    Trends Ecol Evol 23:511-7. 2008
    ..Nevertheless, these models have proven very useful through their highlighting of the importance of within-host disease dynamics on pathogen evolution...
  9. ncbi Transmission-virulence trade-offs in vector-borne diseases
    Samuel Alizon
    Ecole Normale Superieure, UMR 7625 Fonctionnement et Evolution des Systèmes Ecologiques, Paris, F 75005, France
    Theor Popul Biol 74:6-15. 2008
    ..Finally, we compare the effect of treatments targeting either the asexual or the sexual parasite life-stage...
  10. ncbi Emergence of a convex trade-off between transmission and virulence
    Samuel Alizon
    Laboratoire d Ecologie, Centre Nationale de la Recherche Scientifique Unité Mixte de Recherche CNRS UMR 7625, Ecole Normale Superieure, 75005 Paris, France
    Am Nat 165:E155-67. 2005
    ..We discuss possible experiments and implications of our results for the development of virulence management strategies...