K Schwarz

Summary

Affiliation: St. Gallen

Country: Switzerland

Interferon-gamma inducible exchanges of 20S proteasome active site subunits: why?
M Groettrup
Research Department, Cantonal Hospital St Gall, 9007, St Gallen, Switzerland
Biochimie 83:367-72. 2001
Structural plasticity of the proteasome and its function in antigen processing
M Groettrup
Research Department, Cantonal Hospital St Gallen, Switzerland
Crit Rev Immunol 21:339-58. 2001
Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver
S Khan
Research Department and Institute for Pathology, Cantonal Hospital St Gallen, St Gallen, Switzerland
J Immunol 167:6859-68. 2001

Interferon-gamma inducible exchanges of 20S proteasome active site subunits: why?
M Groettrup
Research Department, Cantonal Hospital St Gall, 9007, St Gallen, Switzerland
Biochimie 83:367-72. 2001
..This difference in epitope generation may serve to better stimulate T cells in the sites of an ongoing immune response and to avoid autoimmunity in uninflamed tissues...
Structural plasticity of the proteasome and its function in antigen processing
M Groettrup
Research Department, Cantonal Hospital St Gallen, Switzerland
Crit Rev Immunol 21:339-58. 2001
..Moreover, we review the latest data on how the ubiquitin pathway targets protein antigens for peptide processing and discuss the potential of proteasome inhibitors for the modulation of antigen presentation...
Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver
S Khan
Research Department and Institute for Pathology, Cantonal Hospital St Gallen, St Gallen, Switzerland
J Immunol 167:6859-68. 2001
....