Adrien W Schmid
- Tissue transglutaminase-mediated glutamine deamidation of beta-amyloid peptide increases peptide solubility, whereas enzymatic cross-linking and peptide fragmentation may serve as molecular triggers for rapid peptide aggregationAdrien W Schmid
Proteomics Core Facility, AI 0151, Station 15, Institute of Chemical Sciences and Engineering, Lausanne, Switzerland
J Biol Chem 286:12172-88. 2011..Our in depth analyses indicate that TGase-induced post-translational modifications of Aβ peptide may serve as an important seed for aggregation...
- Alpha-synuclein post-translational modifications as potential biomarkers for Parkinson disease and other synucleinopathiesAdrien W Schmid
Proteomics Core Facility, School of Life Sciences, Station 19, Ecole Polytechnique Federale de Lausanne, CH 1015 Lausanne, Switzerland
Mol Cell Proteomics 12:3543-58. 2013....
- Dissecting the mechanisms of tissue transglutaminase-induced cross-linking of alpha-synuclein: implications for the pathogenesis of Parkinson diseaseAdrien W Schmid
Laboratory of Molecular Neurobiology and Neuroproteomics, Brain Mind Institute, School of Life Sciences, Ecole Polytechnique Federale de Lausanne EPFL, Lausanne, Switzerland
J Biol Chem 284:13128-42. 2009....
- Absolute quantification of transcription factors during cellular differentiation using multiplexed targeted proteomicsJovan Simicevic
Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Federale de Lausanne EPFL, Lausanne, Switzerland
Nat Methods 10:570-6. 2013..This model explains the increase in PPARγ binding sites during the final differentiation stage that occurs despite a concurrent saturation in PPARγ copy number...