W H Reinhart

Summary

Country: Switzerland

Publications

  1. ncbi request reprint Creatine kinase MB during myocardial infarction: relationship to preexisting coronary heart disease and medication
    H Sax
    Kantonsspital, Chur, Switzerland
    Acta Cardiol 52:423-30. 1997
  2. doi request reprint [Dying with living donor transplantation]
    W Reinhart
    Departement Innere Medizin, Kantonsspital Graubunden, Chur
    Ther Umsch 69:683-6. 2012
  3. doi request reprint Platelets in vascular disease
    W H Reinhart
    Department of Internal Medicine, Kantonsspital Graubunden, Chur, Switzerland
    Clin Hemorheol Microcirc 53:71-9. 2013
  4. doi request reprint Activation of N-methyl D-aspartate (NMDA) receptors has no influence on rheological properties of erythrocytes
    W H Reinhart
    Department of Internal Medicine, Kantonsspital Graubunden, Chur, Switzerland
    Clin Hemorheol Microcirc 49:307-13. 2011
  5. doi request reprint Metabolic depletion decreases the aggregability of erythrocytes
    W H Reinhart
    Department of Internal Medicine, Kantonsspital Graubünden and Regional Blood Bank, Swiss Red Cross, Chur, Switzerland
    Clin Hemorheol Microcirc 49:451-61. 2011
  6. doi request reprint [Between thrombosis and bleeding - a case of paroxysmal nocturnal hemoglobinuria]
    Walter H Reinhart
    Departement Innere Medizin, Kantonsspital Graubunden, Chur
    Ther Umsch 67:609-12. 2010
  7. ncbi request reprint [From starving to life-threatening nutrition--the history of an intestinal pseudoobstruction]
    W H Reinhart
    Departement Innere Medizin, Kantonsspital Graubunden, Chur
    Ther Umsch 63:757-61. 2006
  8. ncbi request reprint Stored erythrocytes have less capacity than normal erythrocytes to support primary haemostasis
    Walter H Reinhart
    Department of Internal Medicine, Kantonsspital Graubunden, CH 7000 Chur, Switzerland
    Thromb Haemost 101:720-3. 2009
  9. ncbi request reprint [An unconscious odyssey]
    Walter H Reinhart
    Departement Innere Medizin, Kantonsspital Graubunden, Chur
    Ther Umsch 65:717-20. 2008
  10. doi request reprint Viscosity of human bile sampled from the common bile duct
    Walter H Reinhart
    Department of Internal Medicine, Kantonsspital Graubunden, Chur, Switzerland
    Clin Hemorheol Microcirc 44:177-82. 2010

Collaborators

Detail Information

Publications39

  1. ncbi request reprint Creatine kinase MB during myocardial infarction: relationship to preexisting coronary heart disease and medication
    H Sax
    Kantonsspital, Chur, Switzerland
    Acta Cardiol 52:423-30. 1997
    ..02-0.11, versus 0.04, range 0.02-0.07, p < 0.05). We conclude that relative CK-MBm/CK levels reflect to a certain degree the extent of the coronary disease and that preinfarctional beta-blockade may result in lower CK-MBm levels...
  2. doi request reprint [Dying with living donor transplantation]
    W Reinhart
    Departement Innere Medizin, Kantonsspital Graubunden, Chur
    Ther Umsch 69:683-6. 2012
    ..She refused any further intensive care and died, with the well functioning donated left liver lobe of the daughter dying with her...
  3. doi request reprint Platelets in vascular disease
    W H Reinhart
    Department of Internal Medicine, Kantonsspital Graubunden, Chur, Switzerland
    Clin Hemorheol Microcirc 53:71-9. 2013
    ..Newer agents are being developed with the difficult mission to inhibit platelet aggregation more efficiently, and simultaneously reduce the risk of bleeding...
  4. doi request reprint Activation of N-methyl D-aspartate (NMDA) receptors has no influence on rheological properties of erythrocytes
    W H Reinhart
    Department of Internal Medicine, Kantonsspital Graubunden, Chur, Switzerland
    Clin Hemorheol Microcirc 49:307-13. 2011
    ..Red blood cells (RBCs) express N-methyl D-aspartate (NMDA) receptors on their surface. We tested if NMDA receptor activation or inhibition had an influence on RBC deformability and aggregability...
  5. doi request reprint Metabolic depletion decreases the aggregability of erythrocytes
    W H Reinhart
    Department of Internal Medicine, Kantonsspital Graubünden and Regional Blood Bank, Swiss Red Cross, Chur, Switzerland
    Clin Hemorheol Microcirc 49:451-61. 2011
    ..These ATP-depleted, but normally shaped RBCs had a decreased aggregability. In contrast to all other methods used, low shear viscosity was inaccurate and should not be used to test RBC aggregability...
  6. doi request reprint [Between thrombosis and bleeding - a case of paroxysmal nocturnal hemoglobinuria]
    Walter H Reinhart
    Departement Innere Medizin, Kantonsspital Graubunden, Chur
    Ther Umsch 67:609-12. 2010
    ..This tragic case illustrates that an antithrombotic treatment is always a balancing act with an unsecure outcome...
  7. ncbi request reprint [From starving to life-threatening nutrition--the history of an intestinal pseudoobstruction]
    W H Reinhart
    Departement Innere Medizin, Kantonsspital Graubunden, Chur
    Ther Umsch 63:757-61. 2006
    ..She also survived this second heart surgery and is currently under parenteral nutrition again, with a more than uncertain future...
  8. ncbi request reprint Stored erythrocytes have less capacity than normal erythrocytes to support primary haemostasis
    Walter H Reinhart
    Department of Internal Medicine, Kantonsspital Graubunden, CH 7000 Chur, Switzerland
    Thromb Haemost 101:720-3. 2009
    ....
  9. ncbi request reprint [An unconscious odyssey]
    Walter H Reinhart
    Departement Innere Medizin, Kantonsspital Graubunden, Chur
    Ther Umsch 65:717-20. 2008
    ..Why could nobody prevent or stop this insane odyssey?..
  10. doi request reprint Viscosity of human bile sampled from the common bile duct
    Walter H Reinhart
    Department of Internal Medicine, Kantonsspital Graubunden, Chur, Switzerland
    Clin Hemorheol Microcirc 44:177-82. 2010
    ..We conclude that bile viscosity in the common bile duct is usually lower than that of plasma, in 15% it is higher and increases exponentially with decreasing flow rate, which may lead to a vicious cycle...
  11. doi request reprint The influence of erythrocyte aggregation on induced platelet aggregation
    C Ott
    Department of Internal Medicine and Division of Transfusion Medicine, Kantonsspital Graubunden, Chur, Switzerland
    Clin Hemorheol Microcirc 45:375-82. 2010
    ..Our data suggest that RBC aggregation does not affect platelet aggregation in vitro and plays no role in primary hemostasis...
  12. doi request reprint Overhead rotation: A simple method to assess the mechanical stability of stored erythrocytes
    T Schulzki
    Division of Transfusion Medicine and Department of Internal Medicine, Kantonsspital, Graubunden, Chur, Switzerland
    Clin Hemorheol Microcirc 45:383-9. 2010
    ..Large variations between different RBC units suggest that this may be valuable tool for the quality control of stored RBCs...
  13. ncbi request reprint Effects of high-altitude exposure on vascular endothelial growth factor levels in man
    R Walter
    Department Innere Medizin, Kantonsspital, Chur, Switzerland
    Eur J Appl Physiol 85:113-7. 2001
    ..We conclude that VEGF release is stimulated at high altitude, but that VEGF is probably not related to high-altitude illness...
  14. ncbi request reprint Influence of blood withdrawal and anticoagulant on clotting activity, hematologic data, and certain rheologic measurements
    W H Reinhart
    Department of Internal Medicine, University of Berne, Inselspital, Switzerland
    J Lab Clin Med 115:98-103. 1990
    ..The results suggest that EDTA is probably a reasonable choice for rheologic studies of whole blood and should be combined with PPACK when plasma properties are studied...
  15. pmc Commercial taxane formulations induce stomatocytosis and increase blood viscosity
    M Mark
    Department of Internal Medicine, Kantonsspital, CH-7000 Chur, Switzerland
    Br J Pharmacol 134:1207-14. 2001
    ..4. Commercial taxane drug formulations induce stomatocytosis and increase blood viscosity, which is due to their formulation vehicles. These findings may contribute to the understanding of the cardiovascular side effects of these drugs...
  16. doi request reprint The influence of bevacizumab on platelet function
    M Fehr
    Division of Oncology, Department of Medicine, Kantonsspital Graubunden, Loéstrasse, Chur, CH
    Swiss Med Wkly 141:w13243. 2011
    ..Our data do not support the view that increased platelet activation or increased platelet adhesiveness and aggregation by bevacizumab are relevant mechanisms for thrombus formation in clinical practice...
  17. ncbi request reprint Influence of propofol on erythrocyte morphology, blood viscosity and platelet function
    W H Reinhart
    Department of Internal Medicine, Kantonsspital, CH 7000 Chur, Switzerland
    Clin Hemorheol Microcirc 29:33-40. 2003
    ..We conclude that propofol interacts with the erythrocyte membrane without affecting blood and plasma viscosity and decreases platelet aggregation, which may have clinical implications...
  18. ncbi request reprint Oscillating viscometer--evaluation of a new bedside test
    M Mark
    Internal Medicine, Kantonsspital, CH 7000 Chur, Switzerland
    Biorheology 43:133-46. 2006
    ..We conclude that oscillating viscometry is an interesting bedside test, which is capable of providing new information on the biorheology of the erythrocyte-poor boundary layer near the vessel wall...
  19. ncbi request reprint Viscosity measurements on very small capillary blood samples
    M Eugster
    Internal Medicine, Kantonsspital, Chur, Switzerland
    Clin Hemorheol Microcirc 36:195-202. 2007
    ..It remains to be determined if such new informations have clinical implications...
  20. ncbi request reprint Blood viscosity and platelet function in patients with obstructive sleep apnea syndrome treated with nasal continuous positive airway pressure
    W H Reinhart
    Department of Internal Medicine, Kantonsspital, Switzerland
    Clin Hemorheol Microcirc 27:201-7. 2002
    ..The increase of plasma viscosity and fibrinogen in OSA patients as well as the general increase of platelet aggregation in the morning may contribute to the increased incidence of cardiovascular events...
  21. ncbi request reprint No influence of C-peptide, insulin, and glucagon on blood viscosity in vitro in healthy humans and patients with diabetes mellitus
    L Schnyder
    Department of Internal Medicine, Kantonsspital, Switzerland
    Clin Hemorheol Microcirc 24:65-74. 2001
    ..It is, therefore, unlikely that microvascular disturbances seen with either deficiency or excess of these hormones is due to haemorheological factors...
  22. ncbi request reprint Influence of a parenteral fish-oil preparation (Omegaven) on erythrocyte morphology and blood viscosity in vitro
    L Fischler
    Department of Internal Medicine, Kantonsspital, CH 7000 Chur, Switzerland
    Clin Hemorheol Microcirc 28:79-88. 2003
    ..We conclude that the intravenous fish-oil preparation Omegaven interacts with the outer hemileaflet of the erythrocyte membrane and may affect membrane functions. At pharmacological concentrations these effects seem to be negligeable...
  23. ncbi request reprint Pharmacological concentrations of arginine influence human whole blood viscosity independent of nitric oxide synthase activity in vitro
    R Walter
    Department of Internal Medicine, Kantonsspital, Chur, Switzerland
    Biochem Biophys Res Commun 269:687-91. 2000
    ..We conclude that high concentrations amino acids may decrease blood viscosity at low shear rate independent of NOS activity. This effect may contribute to the improved blood flow after intravascular administration of l-arginine...
  24. doi request reprint Acute effects of short-term exposure to second-hand smoke on induced platelet aggregation
    E Lardi
    Department of Internal Medicine, Kantonsspital Graubunden, Chur, Switzerland
    Clin Hemorheol Microcirc 45:359-64. 2010
    ..We conclude that acute exposure to second-hand smoke is unlikely to increase platelet aggregability. Other mechanisms must be involved in the increased risk of cardiovascular events associated with passive smoking...
  25. ncbi request reprint The passage of a hemodialysis filter affects hemorheology, red cell shape, and platelet aggregation
    W H Reinhart
    Department of Internal Medicine, Kantonsspital Graubunden, Chur, Switzerland
    Clin Hemorheol Microcirc 57:49-62. 2014
    ..We conclude that the passage of a hemodialysis filter induced RBC shape changes, increased the hematocrit, whole blood and plasma viscosity, decreased RBC aggregation, and affected platelet aggregation. ..
  26. ncbi request reprint Influence of prestorage leucocyte depletion and storage time on rheologic properties of erythrocyte concentrates
    T Sollberger
    Department of Internal Medicine, Kantonsspital, Chur, Switzerland
    Vox Sang 82:191-7. 2002
    ..Rheological blood properties were studied during storage...
  27. ncbi request reprint How important is malnutrition? A prospective study in internal medicine
    R M Venzin
    Department of Internal Medicine, Kantonsspital Graubunden, Chur, Switzerland
    Eur J Clin Nutr 63:430-6. 2009
    ..Data about the prevalence of malnutrition on hospital admission vary and follow-up data are scarce. We assessed the nutritional status of unselected patients on admission and discharge...
  28. doi request reprint Particulate matter inhalation during hay storing activity induces systemic inflammation and platelet aggregation
    B Schicker
    Department of Internal Medicine, Kantonsspital Graubunden, 7000, Chur, Switzerland
    Eur J Appl Physiol 105:771-8. 2009
    ..These results confirm that acute inhalative exposure to high PM(10) concentrations during hay storage activity leads to a systemic inflammatory reaction, endothelial activation, and platelet aggregation...
  29. doi request reprint Studies on metabolically depleted erythrocytes
    S A Reinhart
    Department of Internal Medicine, Kantonsspital Graubunden, Chur, Switzerland
    Clin Hemorheol Microcirc 56:161-73. 2014
    ..2% albumin. This phenomenon is specific for albumin, since molecules with a similar molecular weight (dextran 70, heat shock protein, protein C) had no effect. These finding may have an impact on blood banking and transfusion medicine. ..
  30. ncbi request reprint Platelet count and function at high altitude and in high-altitude pulmonary edema
    T Lehmann
    Dept of Internal Medicine, Kantonsspital, CH 7000 Chur, Switzerland
    J Appl Physiol 100:690-4. 2006
    ..These effects are, however, not more pronounced in individuals with a history of HAPE or actually suffering from HAPE than in controls and therefore may not be a pathophysiological mechanism of HAPE...
  31. doi request reprint Erythrocyte storage in hypertonic (SAGM) or isotonic (PAGGSM) conservation medium: influence on cell properties
    L Zehnder
    Department of Internal Medicine, Kantonsspital Graubunden, Chur, Switzerland
    Vox Sang 95:280-7. 2008
    ..A contributing factor is RBC storage lesions. We analysed the role of additive conservation solutions, either hypertonic or isotonic, on such cell properties...
  32. ncbi request reprint Molecular biology and self-regulatory mechanisms of blood viscosity: a review
    W H Reinhart
    Department of Internal Medicine, Kantonsspital, Chur, Switzerland
    Biorheology 38:203-12. 2001
    ..Further investigations into these self-regulatory mechanisms in biorheology are, however, needed for a better understanding of blood viscosity regulation in health and disease...
  33. ncbi request reprint Influence of parenteral nutrition on blood rheology and platelet aggregation in vitro
    S C Compagnoni
    Department of Internal Medicine, Kantonsspital Graubunden, Chur, Switzerland
    Biorheology 51:187-96. 2014
    ..Parenteral nutrition (PN) is a hyperosmolar solution composed of glucose, amino acids and a lipid emulsion, which is often used despite well-known side effects and complications...
  34. ncbi request reprint Cocaine induces a reversible stomatocytosis of red blood cells and increases blood viscosity
    F Cagienard
    Department of Internal Medicine, Kantonsspital Graubunden, Chur, Switzerland
    Clin Hemorheol Microcirc 55:321-9. 2013
    ..These effects occurred at a cocaine concentration, which is several-fold above those measured in vivo. Therefore, it is unlikely that hemorheological factors are involved in vascular events after cocaine consumption...
  35. doi request reprint [Herbal drugs mimicking primary biliary cirrhosis]
    C Elbl
    Department Innere Medizin, Kantonsspital Graubunden, Chur
    Praxis (Bern 1994) 101:195-8. 2012
    ..A second biopsy of the liver three months later showed a clear decline of the initial histologic changes...
  36. ncbi request reprint [Diarrhea and weight loss in common variable immunodeficiency]
    Z Liesch
    Departement Innere Medizin, Kantonsspital, Chur, Schweiz
    Z Gastroenterol 42:599-603. 2004
    ..This case report focuses on CVID as a potential underlying cause of diarrhea. The most important complications of the disease are presented. Therapeutical options are discussed in the light of recently published data...
  37. ncbi request reprint Drug-induced bronchospasm: analysis of 187 spontaneously reported cases
    J D Leuppi
    Department of Internal Medicine, Kantonsspital, Switzerland
    Respiration 68:345-51. 2001
    ..CONCLUSION: Drug-induced bronchospasm is frequently reported with NSAIDs, anti-infective agents, cardiovascular drugs and excipients with a high proportion of serious reactions...
  38. ncbi request reprint [Stenting ovation?]
    W H Reinhart
    Ther Umsch 60:177. 2003
  39. ncbi request reprint Transregional spread of a single clone of methicillin-resistant Staphylococcus aureus between groups of drug users in Switzerland
    F Fleisch
    Dept of Internal Medicine and Laboratory of Microbiology, Kantonsspital, 7000 Chur, Switzerland
    Infection 33:273-7. 2005
    ..An epidemic spread of methicillin-resistant Staphylococcus aureus (MRSA) among intravenous drug users (IDUs) has been observed in Zurich. In the present study we investigated the situation in the Grisons, Switzerland...