Pascal Mottier

Summary

Country: Switzerland

Publications

  1. ncbi request reprint Comparison of gas chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry methods to quantify alpha-tocopherol and alpha-tocopherolquinone levels in human plasma
    Pascal Mottier
    Nestle Research Center, Nestec Ltd, Vers chez les Blanc, Lausanne 26, 1000, Switzerland
    Anal Biochem 301:128-35. 2002
  2. ncbi request reprint Determination of the antibiotic chloramphenicol in meat and seafood products by liquid chromatography-electrospray ionization tandem mass spectrometry
    Pascal Mottier
    Nestle Research Center, Nestec Ltd Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Chromatogr A 994:75-84. 2003
  3. ncbi request reprint Quantitative determination of four nitrofuran metabolites in meat by isotope dilution liquid chromatography-electrospray ionisation-tandem mass spectrometry
    Pascal Mottier
    Department of Quality and Safety Assurance, Nestle Research Centre, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Chromatogr A 1067:85-91. 2005
  4. ncbi request reprint Quantitative high-throughput analysis of 16 (fluoro)quinolones in honey using automated extraction by turbulent flow chromatography coupled to liquid chromatography-tandem mass spectrometry
    Pascal Mottier
    Nestle Research Center, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Agric Food Chem 56:35-43. 2008
  5. ncbi request reprint Analysis of four 5-nitroimidazoles and their corresponding hydroxylated metabolites in egg, processed egg, and chicken meat by isotope dilution liquid chromatography tandem mass spectrometry
    Pascal Mottier
    Nestle Research Center, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Agric Food Chem 54:2018-26. 2006
  6. ncbi request reprint Analysis of matrix-bound nitrofuran residues in worldwide-originated honeys by isotope dilution high-performance liquid chromatography-tandem mass spectrometry
    Seu Ping Khong
    Nestle Research Center, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Agric Food Chem 52:5309-15. 2004
  7. doi request reprint Use of molecularly imprinted solid-phase extraction sorbent for the determination of four 5-nitroimidazoles and three of their metabolites from egg-based samples before tandem LC-ESIMS/MS analysis
    Rayane Mohamed
    Nestle Research Center, Nestec Ltd, P O Box 44, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Agric Food Chem 56:3500-8. 2008
  8. ncbi request reprint Preparation of stable isotope-labeled 2-nitrobenzaldehyde derivatives of four metabolites of nitrofuran antibiotics and their comprehensive characterization by UV, MS, and NMR techniques
    Thierry Delatour
    Nestle Research Center, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Agric Food Chem 51:6371-9. 2003
  9. ncbi request reprint Advantages of molecularly imprinted polymers LC-ESI-MS/MS for the selective extraction and quantification of chloramphenicol in milk-based matrixes. comparison with a classical sample preparation
    Rayane Mohamed
    Nestle Research Center, Nestec Limited, P O Box 44, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    Anal Chem 79:9557-65. 2007
  10. ncbi request reprint Quantitative determination of chloramphenicol in milk powders by isotope dilution liquid chromatography coupled to tandem mass spectrometry
    Philippe A Guy
    Department of Quality and Safety Assurance, Nestle Research Center, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Chromatogr A 1054:365-71. 2004

Detail Information

Publications17

  1. ncbi request reprint Comparison of gas chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry methods to quantify alpha-tocopherol and alpha-tocopherolquinone levels in human plasma
    Pascal Mottier
    Nestle Research Center, Nestec Ltd, Vers chez les Blanc, Lausanne 26, 1000, Switzerland
    Anal Biochem 301:128-35. 2002
    ..Both techniques showed that the ratio of TQ/TH was elevated by 35% immediately after exercise and had returned to basal levels when measured 24 h later...
  2. ncbi request reprint Determination of the antibiotic chloramphenicol in meat and seafood products by liquid chromatography-electrospray ionization tandem mass spectrometry
    Pascal Mottier
    Nestle Research Center, Nestec Ltd Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Chromatogr A 994:75-84. 2003
    ..The method is robust and suitable for routine quality control operations, and more than 200 sample injections were performed without excessive pollution of the mass spectrometer or loss of LC column performance...
  3. ncbi request reprint Quantitative determination of four nitrofuran metabolites in meat by isotope dilution liquid chromatography-electrospray ionisation-tandem mass spectrometry
    Pascal Mottier
    Department of Quality and Safety Assurance, Nestle Research Centre, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Chromatogr A 1067:85-91. 2005
    ..The method is robust and suitable for routine quality control operations, and more than 200 sample injections were performed without excessive pollution of the mass spectrometer or loss of LC column performance...
  4. ncbi request reprint Quantitative high-throughput analysis of 16 (fluoro)quinolones in honey using automated extraction by turbulent flow chromatography coupled to liquid chromatography-tandem mass spectrometry
    Pascal Mottier
    Nestle Research Center, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Agric Food Chem 56:35-43. 2008
    ....
  5. ncbi request reprint Analysis of four 5-nitroimidazoles and their corresponding hydroxylated metabolites in egg, processed egg, and chicken meat by isotope dilution liquid chromatography tandem mass spectrometry
    Pascal Mottier
    Nestle Research Center, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Agric Food Chem 54:2018-26. 2006
    ..Nevertheless, a reliable identification of these two analytes at levels < or = 1 microg/kg was still feasible...
  6. ncbi request reprint Analysis of matrix-bound nitrofuran residues in worldwide-originated honeys by isotope dilution high-performance liquid chromatography-tandem mass spectrometry
    Seu Ping Khong
    Nestle Research Center, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Agric Food Chem 52:5309-15. 2004
    ..12-0.56 microg/kg. The method has been successfully applied in a survey of honeys of various geographical origins, showing that furazolidone is the main nitrofuran antibiotic administered to treat bacterial diseases of bees...
  7. doi request reprint Use of molecularly imprinted solid-phase extraction sorbent for the determination of four 5-nitroimidazoles and three of their metabolites from egg-based samples before tandem LC-ESIMS/MS analysis
    Rayane Mohamed
    Nestle Research Center, Nestec Ltd, P O Box 44, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Agric Food Chem 56:3500-8. 2008
    ..34 and 0.39 microg/kg, respectively...
  8. ncbi request reprint Preparation of stable isotope-labeled 2-nitrobenzaldehyde derivatives of four metabolites of nitrofuran antibiotics and their comprehensive characterization by UV, MS, and NMR techniques
    Thierry Delatour
    Nestle Research Center, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Agric Food Chem 51:6371-9. 2003
    ..A major advantage of the described procedure is that it can be extended to the preparation of other carbon-13-labeled derivatives of metabolites of nitrofuran antibiotics...
  9. ncbi request reprint Advantages of molecularly imprinted polymers LC-ESI-MS/MS for the selective extraction and quantification of chloramphenicol in milk-based matrixes. comparison with a classical sample preparation
    Rayane Mohamed
    Nestle Research Center, Nestec Limited, P O Box 44, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    Anal Chem 79:9557-65. 2007
    ..The decision limit (CCalpha) and detection capability (CCbeta) were calculated to be 0.06 and 0.10 microg/kg, respectively...
  10. ncbi request reprint Quantitative determination of chloramphenicol in milk powders by isotope dilution liquid chromatography coupled to tandem mass spectrometry
    Philippe A Guy
    Department of Quality and Safety Assurance, Nestle Research Center, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Chromatogr A 1054:365-71. 2004
    ..This method can be applied to several types of milk powders (e.g. full cream, skim) and can serve as a monitoring tool to avoid that unacceptable levels of residues of CAP enter the food chain...
  11. doi request reprint Simultaneous quantitative determination of melamine and cyanuric acid in cow's milk and milk-based infant formula by liquid chromatography-electrospray ionization tandem mass spectrometry
    Aurelien Desmarchelier
    Nestle Research Centre, Nestec Ltd, Vers chez les Blanc, Lausanne 26, Switzerland
    J Agric Food Chem 57:7186-93. 2009
    ..CCalpha and CCbeta, at the 1 mg/kg maximum limit (ML) for infant formula powder endorsed by WHO, were respectively 1.03 and 1.05 mg/kg for melamine and 1.04 and 1.09 mg/kg for cyanuric acid...
  12. ncbi request reprint Semicarbazide is a minor thermal decomposition product of azodicarbonamide used in the gaskets of certain food jars
    Richard H Stadler
    Nestle Research Center, Nestec Ltd, Vers chez les Blanc, CH 1000 Lausanne 26, Switzerland
    Analyst 129:276-81. 2004
    ..A limited survey of plastic seals from used press twist and twist-off metal lids on food jars (non-foamed and foamed) revealed levels of SEM ranging from 2 to 8689 microg kg(-1)(average = 1593 microg kg(-1), n= 57 determinations)...
  13. doi request reprint Development and comparison of two multiresidue methods for the analysis of 17 mycotoxins in cereals by liquid chromatography electrospray ionization tandem mass spectrometry
    Aurelien Desmarchelier
    Nestle Research Centre, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Agric Food Chem 58:7510-9. 2010
    ..5 microg/kg for ochratoxin A, and the 5-100 microg/kg range for all other mycotoxins tested. The QuEChERS-like method was found to be easier to handle and allowed a higher sample throughput as compared to the ASE method...
  14. ncbi request reprint Limits of suspicion, recognition and confirmation as concepts that account for the confirmation transitions at the detection limit for quantification by liquid chromatography-tandem mass spectrometry
    Thierry Delatour
    Nestle Research Centre, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Chromatogr A 1169:103-10. 2007
    ..For these three limits, applications and drawbacks are shown, while determination methods are proposed...
  15. ncbi request reprint A comparative study of proteolysis methods for the measurement of 3-nitrotyrosine residues: enzymatic digestion versus hydrochloric acid-mediated hydrolysis
    Thierry Delatour
    Nestle Research Center, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    J Chromatogr B Analyt Technol Biomed Life Sci 851:268-76. 2007
    ..We additionally show that the enzyme efficacy is not altered when the digestion is carried out in the presence of BSA with a high content of NY...
  16. doi request reprint Combining the quick, easy, cheap, effective, rugged and safe approach and clean-up by immunoaffinity column for the analysis of 15 mycotoxins by isotope dilution liquid chromatography tandem mass spectrometry
    Aurelien Desmarchelier
    Nestle Research Centre, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland Electronic address
    J Chromatogr A 1337:75-84. 2014
    ..Method ruggedness was proved by a verification process conducted by another laboratory. ..
  17. ncbi request reprint Determination of alpha-tocopherol in infant foods by liquid chromatography combined with atmospheric pressure chemical ionisation mass spectrometry
    Andras Kalman
    Department of Quality Assurance, Nestle Research Center, Nestec Ltd, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    Rapid Commun Mass Spectrom 17:723-7. 2003
    ..This would simplify the preparation of the food samples and consequently enhance the vitamin analysis throughput in the food area...