Matthias Lutolf

Summary

Country: Switzerland

Publications

  1. ncbi Designing materials to direct stem-cell fate
    Matthias P Lutolf
    Institute of Bioengineering, Ecole Polytechnique Federale de Lausanne, CH 1015 Lausanne, Switzerland
    Nature 462:433-41. 2009
  2. ncbi Patterning of cell-instructive hydrogels by hydrodynamic flow focusing
    Steffen Cosson
    Laboratory of Stem Cell Bioengineering, Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Federale de Lausanne, Station 15, Bldg AI 1109, CH 1015 Lausanne, Switzerland
    Lab Chip 13:2099-105. 2013
  3. ncbi Automated analysis of single stem cells in microfluidic traps
    Stefan A Kobel
    Laboratory of Stem Cell Bioengineering LSCB, Institute of Bioengineering and School of Life Sciences, Ecole Polytechnique Federale de Lausanne EPFL, CH 1015, Lausanne, Switzerland
    Lab Chip 12:2843-9. 2012
  4. ncbi Diagnostic microchip to assay 3D colony-growth potential of captured circulating tumor cells
    Colette A Bichsel
    School of Life Sciences, Institute of Bioengineering and Laboratory of Stem Cell Bioengineering, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland
    Lab Chip 12:2313-6. 2012
  5. ncbi High-throughput clonal analysis of neural stem cells in microarrayed artificial niches
    Marta Roccio
    School of Life Sciences, Institute of Bioengineering and Laboratory of Stem Cell Bioengineering, Ecole Polytechnique Federale de Lausanne EPFL, Switzerland
    Integr Biol (Camb) 4:391-400. 2012
  6. ncbi Integration column: artificial ECM: expanding the cell biology toolbox in 3D
    Matthias P Lutolf
    Laboratory of Stem Cell Bioengineering and Institute of Bioengineering, Ecole Polytechnique Federale de Lausanne EPFL, Switzerland
    Integr Biol (Camb) 1:235-41. 2009
  7. ncbi Artificial stem cell niches
    Matthias P Lutolf
    Institute of Bioengineering, Ecole Polytechnique Federale de Lausanne, Switzerland
    Adv Mater 21:3255-68. 2009
  8. ncbi Programmable microfluidic patterning of protein gradients on hydrogels
    Simone Allazetta
    Laboratory of Stem Cell Bioengineering, Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne Station 15 Bldg AI 1109, CH 1015 Lausanne, Switzerland
    Chem Commun (Camb) 47:191-3. 2011
  9. ncbi High-throughput methods to define complex stem cell niches
    Stefan Kobel
    Laboratory of Stem Cell Bioengineering LSCB and Institute of Bioengineering IBI, Ecole Polytechnique Federale de Lausanne EPFL, Lausanne, Switzerland
    Biotechniques 48:ix-xxii. 2010

Collaborators

  • Steffen Cosson
  • Simone Allazetta
  • Stefan Kobel
  • Stefan A Kobel
  • Samy Gobaa
  • Colette A Bichsel
  • Marta Roccio
  • Arne Seitz
  • Chiara Secondini
  • Marco G Cecchini
  • Mukul Girotra
  • George N Thalmann
  • Olivier Burri
  • Alexandra Griffa

Detail Information

Publications9

  1. ncbi Designing materials to direct stem-cell fate
    Matthias P Lutolf
    Institute of Bioengineering, Ecole Polytechnique Federale de Lausanne, CH 1015 Lausanne, Switzerland
    Nature 462:433-41. 2009
    ..Further synergism of cell biological and biomaterials technologies promises to have a profound impact on stem-cell biology and provide insights that will advance stem-cell-based clinical approaches to tissue regeneration...
  2. ncbi Patterning of cell-instructive hydrogels by hydrodynamic flow focusing
    Steffen Cosson
    Laboratory of Stem Cell Bioengineering, Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Federale de Lausanne, Station 15, Bldg AI 1109, CH 1015 Lausanne, Switzerland
    Lab Chip 13:2099-105. 2013
    ..Our concept should be broadly applicable to probe how complex signaling microenvironments influence stem cell fate in culture...
  3. ncbi Automated analysis of single stem cells in microfluidic traps
    Stefan A Kobel
    Laboratory of Stem Cell Bioengineering LSCB, Institute of Bioengineering and School of Life Sciences, Ecole Polytechnique Federale de Lausanne EPFL, CH 1015, Lausanne, Switzerland
    Lab Chip 12:2843-9. 2012
    ..This approach should be applicable to automatically track single live cells in a wealth of microfluidic systems...
  4. ncbi Diagnostic microchip to assay 3D colony-growth potential of captured circulating tumor cells
    Colette A Bichsel
    School of Life Sciences, Institute of Bioengineering and Laboratory of Stem Cell Bioengineering, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland
    Lab Chip 12:2313-6. 2012
    ....
  5. ncbi High-throughput clonal analysis of neural stem cells in microarrayed artificial niches
    Marta Roccio
    School of Life Sciences, Institute of Bioengineering and Laboratory of Stem Cell Bioengineering, Ecole Polytechnique Federale de Lausanne EPFL, Switzerland
    Integr Biol (Camb) 4:391-400. 2012
    ..We believe that the bioengineering of such in vitro niche analogues is a powerful approach to elucidate single stem cell fate regulation in a well-controlled fashion...
  6. ncbi Integration column: artificial ECM: expanding the cell biology toolbox in 3D
    Matthias P Lutolf
    Laboratory of Stem Cell Bioengineering and Institute of Bioengineering, Ecole Polytechnique Federale de Lausanne EPFL, Switzerland
    Integr Biol (Camb) 1:235-41. 2009
    ..Here I will discuss emerging approaches in aECM design, hopefully inspiring cell biologists to apply these systems to address their specific biological question...
  7. ncbi Artificial stem cell niches
    Matthias P Lutolf
    Institute of Bioengineering, Ecole Polytechnique Federale de Lausanne, Switzerland
    Adv Mater 21:3255-68. 2009
    ..Such "artificial niches" constitute potent tools for elucidating stem cell regulatory mechanisms with the capacity to directly impact the development of novel therapeutic strategies for tissue regeneration...
  8. ncbi Programmable microfluidic patterning of protein gradients on hydrogels
    Simone Allazetta
    Laboratory of Stem Cell Bioengineering, Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne Station 15 Bldg AI 1109, CH 1015 Lausanne, Switzerland
    Chem Commun (Camb) 47:191-3. 2011
    ..Computer-controlled hydrodynamic flow focusing was utilized to generate tethered protein gradients of any user-defined shape on the surface of soft synthetic hydrogels...
  9. ncbi High-throughput methods to define complex stem cell niches
    Stefan Kobel
    Laboratory of Stem Cell Bioengineering LSCB and Institute of Bioengineering IBI, Ecole Polytechnique Federale de Lausanne EPFL, Lausanne, Switzerland
    Biotechniques 48:ix-xxii. 2010
    ..Increased merging of microfabrication with advanced biomaterials technologies may ultimately result in functional artificial niches capable of recapitulating extrinsic stem cell regulation in vitro and on a single-cell level...