Research Topics
| Marcel LeuteneggerSummaryCountry: Switzerland Publications
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Publications
Imaging of G protein-coupled receptors in solid-supported planar lipid membranesMarcel Leutenegger
Laboratoire d Optique Biomedicale, Ecole Polytechnique Federale de Lausanne, 1015 Lausanne, Switzerland
Biointerphases 3:FA136. 2008..Ligand-independent aggregation behavior of the GPCRs and quantitative analysis of the fluorescent signals are presented in this work...
Analytical description of STED microscopy performanceMarcel Leutenegger
Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Gottingen, Germany
Opt Express 18:26417-29. 2010..Particular emphasis is placed on fluorescence fluctuation methods such as correlation spectroscopy (FCS) using STED...
Multiple scattering in optical coherence tomography. II. Experimental and theoretical investigation of cross talk in wide-field optical coherence tomographyBoris Karamata
Laboratoire d Optique Biomedicale, Swiss Federal Institute of Technology, CH 1015 Lausanne, Switzerland
J Opt Soc Am A Opt Image Sci Vis 22:1380-8. 2005..This further confirms the validity of the model developed in our companion paper [J. Opt. Soc. Am. A 22, 1369-1379 (2005)]...
Fluorescence correlation spectroscopy with a total internal reflection fluorescence STED microscope (TIRF-STED-FCS)Marcel Leutenegger
Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Gottingen, Germany
Opt Express 20:5243-63. 2012..Together with the estimated axial confinement of about 55 nm, our TIRF-STED nanoscope achieved an almost isotropic and less than 1 attoliter small all-optically induced measurement volume...
A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switchingTanja Brakemann
Max Planck Institute for Biophysical Chemistry, Department of NanoBiophotonics, Gottingen, Germany
Nat Biotechnol 29:942-7. 2011..The switching properties of Dreiklang enable far-field fluorescence nanoscopy in living mammalian cells using both a coordinate-targeted and a stochastic single molecule switching approach...
Detection efficiency in total internal reflection fluorescence microscopyMarcel Leutenegger
Laboratoire d Optique Biomedicale, Ecole Polytechnique Federale de Lausanne, 1015 Lausanne, Switzerland
Opt Express 16:8519-31. 2008..This analysis proved to be useful for quantitative measurements, i.e. the fluorescence detection at a glass???water interface for total internal reflection fluorescence microscopy in an epi- and a trans-illumination configuration...
Diffraction-unlimited all-optical imaging and writing with a photochromic GFPTim Grotjohann
Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Gottingen, Germany
Nature 478:204-8. 2011..The reversible switching also enables all-optical writing of features with subdiffraction size and spacings, which can be used for data storage...
Fast molecular tracking maps nanoscale dynamics of plasma membrane lipidsSteffen J Sahl
Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Gottingen, Germany
Proc Natl Acad Sci U S A 107:6829-34. 2010..Our experimental approach demonstrates that fast molecular movements can be tracked with minimal invasion, which can reveal new important details of cellular nano-organization...
Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5)Matthias Geissbuehler
Laboratoire d Optique Biomedicale, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland
Biophys J 98:339-49. 2010..The proposed method has the potential to become a new tool for investigating oxygen metabolism at the single cell and the subcellular level...
Multiple scattering in optical coherence tomography. I. Investigation and modelingBoris Karamata
Laboratoire d Optique Biomedicale, Swiss Federal Institute of Technology, CH 1015 Lausanne, Switzerland
J Opt Soc Am A Opt Image Sci Vis 22:1369-79. 2005..We discuss other comprehensive OCT models based on the extended Huygens-Fresnel principle, which rest on the assumption of partially coherent interfering fields...
