- Microdialytical monitoring of uric and ascorbic acids in the brains of patients after severe brain injury and during neurovascular surgeryH Langemann
Neurosurgery Laboratory, Department of Research, Cantonal Hospital, CH 4031 Basel, Switzerland
J Neurol Neurosurg Psychiatry 71:169-74. 2001..The aim was to investigate whether concentrations of uric and ascorbic acids were altered in such patients. Both these compounds play a part in free radical metabolism, which is accelerated after ischaemia and brain injury...
- Extracellular levels of glucose and lactate measured by quantitative microdialysis in the human brainH Langemann
Neurosurgery Laboratory, Department of Research, University Neurosurgical Clinic, Cantonal Hospital, Basel, Switzerland
Neurol Res 23:531-6. 2001..Extracellular glucose levels were positively correlated with blood glucose values measured before the operation, and with extracellular lactate. Results confirm that extracellular glucose is zero when blood glucose is about 2 mM...
- Chronic effects of an aminosteroid on microdialytically measured parameters after experimental middle cerebral artery occlusion in the ratB Alessandri
Department of Research, Cantonal Hospital, Basel, Switzerland
J Clin Neurosci 7:47-51. 2000....
- 17beta-Estradiol reduces cortical lesion size in the glutamate excitotoxicity model by enhancing extracellular lactate: a new neuroprotective pathwayA Mendelowitsch
Neurosurgical University Clinic, Department of Research, Cantonal Hospital Basel, Basel, Switzerland
Brain Res 901:230-6. 2001..These results suggest a new neuroprotective mechanism of 17beta-estradiol by activating glutamate-stimulated lactate production, which is estrogen receptor-dependent...