Felix Kessler

Summary

Country: Switzerland

Publications

  1. ncbi request reprint Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles
    Pierre Alexandre Vidi
    Institute of Botany, University of Neuchatel, Emile Argand 11, CH 2007 Neuchatel, Switzerland
    J Biol Chem 281:11225-34. 2006
  2. doi request reprint Preparation of multiprotein complexes from Arabidopsis chloroplasts using tandem affinity purification
    Charles Andres
    Plant Physiology Laboratory, University of Neuchatel, Neuchatel, Switzerland
    Methods Mol Biol 775:31-49. 2011
  3. pmc A novel method for prenylquinone profiling in plant tissues by ultra-high pressure liquid chromatography-mass spectrometry
    Jacopo Martinis
    Chemical Analytical Service of the Swiss Plant Science Web, University of Neuchatel, 2000 Neuchatel, Switzerland
    Plant Methods 7:23. 2011
  4. ncbi request reprint Plastoglobule lipid bodies: their functions in chloroplasts and their potential for applications
    Felix Kessler
    Institute of Botany, University of Neuchatel, Emile Argand 11, CP158, 2009, Neuchatel, Switzerland
    Adv Biochem Eng Biotechnol 107:153-72. 2007
  5. ncbi request reprint Chloroplast protein import: solve the GTPase riddle for entry
    Felix Kessler
    Laboratoire de Physiologie Vegetale, Institute de Botanique, Universite de Neuchatel, Rue Emile Argand 11, 2007 Neuchatel, Switzerland
    Trends Cell Biol 14:334-8. 2004
  6. ncbi request reprint The function and diversity of plastid protein import pathways: a multilane GTPase highway into plastids
    Felix Kessler
    Laboratoire de Physiologie Vegetale, Institut de Botanique, Universite de Neuchatel, Rue Emile Argand 11, 2007 Neuchatel, Switzerland
    Traffic 7:248-57. 2006
  7. pmc The acidic A-domain of Arabidopsis TOC159 occurs as a hyperphosphorylated protein
    Birgit Agne
    Laboratoire de Physiologie Vegetale, Universite de Neuchatel, CH 2009 Neuchatel, Switzerland
    Plant Physiol 153:1016-30. 2010
  8. doi request reprint Plastid lipid droplets at the crossroads of prenylquinone metabolism
    Lucia Eugeni Piller
    Laboratoire de Physiologie Vegetale, Universite de Neuchatel, 2000 Neuchatel, Switzerland
    J Exp Bot 63:1609-18. 2012
  9. doi request reprint In vivo interaction between atToc33 and atToc159 GTP-binding domains demonstrated in a plant split-ubiquitin system
    Gwendoline Rahim
    Laboratoire de Physiologie Vegetale, Institut de Biologie, Universite de Neuchatel, Rue Emile Argand 11, CH 2009 Neuchatel, Switzerland
    J Exp Bot 60:257-67. 2009
  10. doi request reprint The chloroplast import receptor Toc90 partially restores the accumulation of Toc159 client proteins in the Arabidopsis thaliana ppi2 mutant
    Sibylle Infanger
    Laboratoire de Physiologie Vegetale, Universite de Neuchatel, Rue Emile Argand 11, 2000 Neuchatel, Switzerland
    Mol Plant 4:252-63. 2011

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles
    Pierre Alexandre Vidi
    Institute of Botany, University of Neuchatel, Emile Argand 11, CH 2007 Neuchatel, Switzerland
    J Biol Chem 281:11225-34. 2006
    ..Thus, in addition to their lipid storage function, we propose that plastoglobules are metabolically active, taking part in tocopherol synthesis and likely other pathways...
  2. doi request reprint Preparation of multiprotein complexes from Arabidopsis chloroplasts using tandem affinity purification
    Charles Andres
    Plant Physiology Laboratory, University of Neuchatel, Neuchatel, Switzerland
    Methods Mol Biol 775:31-49. 2011
    ..PLoS ONE 4:e6685, 2009). Here, we describe a TAP tag purification method for the purification of protein complexes from total Arabidopsis extracts, that we employed successfully using a TAP-tagged chloroplast outer envelope protein...
  3. pmc A novel method for prenylquinone profiling in plant tissues by ultra-high pressure liquid chromatography-mass spectrometry
    Jacopo Martinis
    Chemical Analytical Service of the Swiss Plant Science Web, University of Neuchatel, 2000 Neuchatel, Switzerland
    Plant Methods 7:23. 2011
    ..abstract:..
  4. ncbi request reprint Plastoglobule lipid bodies: their functions in chloroplasts and their potential for applications
    Felix Kessler
    Institute of Botany, University of Neuchatel, Emile Argand 11, CP158, 2009, Neuchatel, Switzerland
    Adv Biochem Eng Biotechnol 107:153-72. 2007
    ..On the basis of similarities between plastoglobules and seed oleosomes, the potential of plastoglobules for bioengineering applications is discussed...
  5. ncbi request reprint Chloroplast protein import: solve the GTPase riddle for entry
    Felix Kessler
    Laboratoire de Physiologie Vegetale, Institute de Botanique, Universite de Neuchatel, Rue Emile Argand 11, 2007 Neuchatel, Switzerland
    Trends Cell Biol 14:334-8. 2004
    ..Recent studies of protein targeting to chloroplasts suggest a novel mechanism in which GTP-dependent substrate recognition is coupled to a GTP-driven motor that initiates the translocation of proteins into the organelle...
  6. ncbi request reprint The function and diversity of plastid protein import pathways: a multilane GTPase highway into plastids
    Felix Kessler
    Laboratoire de Physiologie Vegetale, Institut de Botanique, Universite de Neuchatel, Rue Emile Argand 11, 2007 Neuchatel, Switzerland
    Traffic 7:248-57. 2006
    ..These different import pathways appear to be necessary to balance the essential physiological role of plastids in cellular metabolism with the demands of cellular differentiation and plant development...
  7. pmc The acidic A-domain of Arabidopsis TOC159 occurs as a hyperphosphorylated protein
    Birgit Agne
    Laboratoire de Physiologie Vegetale, Universite de Neuchatel, CH 2009 Neuchatel, Switzerland
    Plant Physiol 153:1016-30. 2010
    ..However, the physiological relevance of this process is unclear. The data show that the A-domain of Toc159 as well as those of its homologs Toc132 and Toc120 are targets of a casein kinase 2-like activity...
  8. doi request reprint Plastid lipid droplets at the crossroads of prenylquinone metabolism
    Lucia Eugeni Piller
    Laboratoire de Physiologie Vegetale, Universite de Neuchatel, 2000 Neuchatel, Switzerland
    J Exp Bot 63:1609-18. 2012
    ..In this review the function of PGs and their associated enzymes in prenylquinone metabolism will be discussed...
  9. doi request reprint In vivo interaction between atToc33 and atToc159 GTP-binding domains demonstrated in a plant split-ubiquitin system
    Gwendoline Rahim
    Laboratoire de Physiologie Vegetale, Institut de Biologie, Universite de Neuchatel, Rue Emile Argand 11, CH 2009 Neuchatel, Switzerland
    J Exp Bot 60:257-67. 2009
    ..Using the same method, the self-interaction of the peroxisomal membrane protein atPex11e is demonstrated. The finding suggests a more general suitability of the split-ubiquitin system as a plant in vivo interaction assay...
  10. doi request reprint The chloroplast import receptor Toc90 partially restores the accumulation of Toc159 client proteins in the Arabidopsis thaliana ppi2 mutant
    Sibylle Infanger
    Laboratoire de Physiologie Vegetale, Universite de Neuchatel, Rue Emile Argand 11, 2000 Neuchatel, Switzerland
    Mol Plant 4:252-63. 2011
    ..Several lines of evidence including proteome profiling demonstrate the import and accumulation of proteins essential for chloroplast biogenesis and functionality...
  11. pmc A toc159 import receptor mutant, defective in hydrolysis of GTP, supports preprotein import into chloroplasts
    Birgit Agne
    Laboratoire de Physiologie Vegetale, Universite de Neuchatel, Rue Emile Argand 11, 2007 Neuchatel, Switzerland
    J Biol Chem 284:8670-9. 2009
    ..The data also indicate that preprotein import requires at least one additional GTPase other than Toc159...
  12. doi request reprint The TOC complex: preprotein gateway to the chloroplast
    Charles Andres
    Institut de Biologie, Universite de Neuchatel, CH 2009 Neuchatel, Switzerland
    Biochim Biophys Acta 1803:715-23. 2010
    ..In this review we will describe the current state of knowledge regarding the composition and function of the TOC complex...
  13. doi request reprint Protein transport in organelles: The Toc complex way of preprotein import
    Birgit Agne
    Laboratoire de Physiologie Vegetale, Universite de Neuchatel, Switzerland
    FEBS J 276:1156-65. 2009
    ..This minireview describes the components of the Toc complex and their function during the initial steps of preprotein translocation across the chloroplast envelope...
  14. pmc Chloroplast lipid droplet type II NAD(P)H quinone oxidoreductase is essential for prenylquinone metabolism and vitamin K1 accumulation
    Lucia Eugeni Piller
    Laboratoire de Physiologie Vegetale, Universite de Neuchatel, 2000 Neuchatel, Switzerland
    Proc Natl Acad Sci U S A 108:14354-9. 2011
    ..Finally, NDC1 is required for normal plastochromanol-8 accumulation and is essential for vitamin K(1) production...
  15. pmc Plastoglobules: a new address for targeting recombinant proteins in the chloroplast
    Pierre Alexandre Vidi
    Institute of Botany, University of Neuchatel, Rue Emile Argand 11, CP158, CH 2009 Neuchatel, Switzerland
    BMC Biotechnol 7:4. 2007
    ..Extraction and purification of recombinant proteins from leaf material contribute to a large extent to the production costs. Developing new strategies facilitating these processes is therefore necessary...
  16. doi request reprint Chloroplast biogenesis: diversity and regulation of the protein import apparatus
    Felix Kessler
    Laboratoire de Physiologie Vegetale, Universite de Neuchatel, Neuchatel, Switzerland
    Curr Opin Cell Biol 21:494-500. 2009
    ..Recent studies also have revealed new components that could represent additional levels of control on the import process...
  17. ncbi request reprint Plastoglobules: versatile lipoprotein particles in plastids
    Claire Bréhélin
    Laboratoire de Physiologie Vegetale, Institut de Biologie, Universite de Neuchatel, Neuchatel, Switzerland
    Trends Plant Sci 12:260-6. 2007
    ..Understanding the function of plastoglobules should provide a foundation for improving the nutritional value and yield of plants...
  18. doi request reprint A mechanism implicating plastoglobules in thylakoid disassembly during senescence and nitrogen starvation
    Celine Besagni
    Laboratoire de Physiologie Vegetale, Universite de Neuchatel, Neuchatel, Switzerland
    Planta 237:463-70. 2013
    ..Recently, the characterization of two phytyl ester synthases has established a firm metabolic link between PG enzymatic activity and thylakoid disassembly during chloroplast senescence and nitrogen starvation...
  19. doi request reprint The plastoglobule: a bag full of lipid biochemistry tricks
    Claire Bréhélin
    Laboratoire de Physiologie Vegetale, Universite de Neuchatel, Neuchatel, Switzerland
    Photochem Photobiol 84:1388-94. 2008
    ..This review will give a summary of research, past and present, attempting to elucidate the role of plastoglobules in the context of plastid function...
  20. ncbi request reprint Dimerization of Toc-GTPases at the chloroplast protein import machinery
    Petra Weibel
    Laboratoire de Physiologie Vegetale, Institut de Botanique, Universite de Neuchatel, Rue Emile Argand 11, 2007 Neuchatel, Switzerland
    J Biol Chem 278:37321-9. 2003
    ..Independent regulation of GTPase activity may serve to coordinate the interactions of the GTPases during the import of proteins into the chloroplast...
  21. pmc A chloroplast ABC1-like kinase regulates vitamin E metabolism in Arabidopsis
    Jacopo Martinis
    Laboratory of Plant Physiology, University of Neuchatel, 2000 Neuchatel, Switzerland
    Plant Physiol 162:652-62. 2013
    ..We provide evidence that the ABC1-like kinase ABC1K3 phosphorylates VTE1, possibly stabilizing it at plastoglobules. However, ABC1K3 may also have other targets and be involved in a wider chloroplast regulatory network...
  22. pmc Plastoglobules are lipoprotein subcompartments of the chloroplast that are permanently coupled to thylakoid membranes and contain biosynthetic enzymes
    Jotham R Austin
    Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Colorado 80309 0347, USA
    Plant Cell 18:1693-703. 2006
    ....
  23. pmc Arabidopsis tic110 is essential for the assembly and function of the protein import machinery of plastids
    Takehito Inaba
    Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts 01003, USA
    Plant Cell 17:1482-96. 2005
    ..Together, these data suggest that Tic110 plays a general role in the import of nuclear-encoded preproteins as a common component of Tic complexes...
  24. ncbi request reprint atTic110 functions as a scaffold for coordinating the stromal events of protein import into chloroplasts
    Takehito Inaba
    Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts 01003, USA
    J Biol Chem 278:38617-27. 2003
    ..These data support the hypothesis that the bulk of Tic110 extends into the chloroplast stroma and suggest that the domain forms a docking site for preproteins as they emerge from the Tic translocon...
  25. pmc The targeting of the atToc159 preprotein receptor to the chloroplast outer membrane is mediated by its GTPase domain and is regulated by GTP
    Matthew D Smith
    Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA
    J Cell Biol 159:833-43. 2002
    ..Our findings demonstrate a role for the coordinate action of the Toc GTPases in assembly of the functional Toc complex at the chloroplast outer envelope membrane...
  26. pmc Essential role of the G-domain in targeting of the protein import receptor atToc159 to the chloroplast outer membrane
    Jörg Bauer
    Plant Physiology and Biochemistry Group, Institute of Plant Sciences, ETH Zurich, CH 8092 Zurich, Switzerland
    J Cell Biol 159:845-54. 2002
    ..Thus, the function of atToc159 in chloroplast biogenesis is dependent on an intrinsic GTP-regulated switch that controls localization of the receptor to the chloroplast envelope...
  27. ncbi request reprint A GTPase gate for protein import into chloroplasts
    Felix Kessler
    Nat Struct Biol 9:81-3. 2002
  28. ncbi request reprint Nitrogen deficiency in Arabidopsis affects galactolipid composition and gene expression and results in accumulation of fatty acid phytyl esters
    Nicole Gaude
    Department of Molecular Physiology, Max Planck Institute of Molecular Plant Physiology, Am Muhlenberg 1, 14476 Golm, Germany
    Plant J 49:729-39. 2007
    ..Therefore N deficiency in higher plants results in a co-ordinated breakdown of galactolipids and chlorophyll with deposition of specific fatty acid phytyl esters in thylakoids and plastoglobules of chloroplasts...
  29. ncbi request reprint AtToc90, a new GTP-binding component of the Arabidopsis chloroplast protein import machinery
    Andreas Hiltbrunner
    Albert Ludwigs Universitat Freiburg, Institut für Biologie II Botanik, Schanzlestrasse 1, D 79104 Freiburg, Germany
    Plant Mol Biol 54:427-40. 2004
    ..As both proteins specifically contribute to the accumulation of photosynthetic proteins in chloroplasts they may be components of the same import pathway...