Werner Kempf

Summary

Country: Switzerland

Publications

  1. doi request reprint MUM1 expression in cutaneous CD30+ lymphoproliferative disorders: a valuable tool for the distinction between lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma
    W Kempf
    Kempf und Pfaltz, Histologische Diagnostik, Schaffhauserplatz 3, CH 8006 Zurich, Switzerland
    Br J Dermatol 158:1280-7. 2008
  2. doi request reprint Critical skin cancer in organ transplant recipients--a dermatopathological view
    Werner Kempf
    Kempf and Pfaltz, Histological Diagnostics, University Hospital Zurich, Seminarstrasse 1, Zurich, Switzerland
    Curr Probl Dermatol 43:18-35. 2012
  3. ncbi request reprint CD4/CD8 double negative mycosis fungoides with PD-1 (CD279) expression--a disease of follicular helper T-cells?
    Werner Kempf
    Kempf und Pfaltz, Histologische Diagnostik, Zurich, Switzerland
    Am J Dermatopathol 34:757-61. 2012
  4. doi request reprint Follicular lymphomatoid papulosis revisited: a study of 11 cases, with new histopathological findings
    Werner Kempf
    Kempf und Pfaltz, Histologische Diagnostik, Zurich, Switzerland
    J Am Acad Dermatol 68:809-16. 2013
  5. doi request reprint Unilesional follicular mycosis fungoides: report of two cases with progression to tumor stage and review of the literature
    Werner Kempf
    Kempf und Pfaltz, Histologische Diagnostik, Zurich, Switzerland
    J Cutan Pathol 39:853-60. 2012
  6. doi request reprint Pityriasis lichenoides et varioliformis acuta with numerous CD30(+) cells: a variant mimicking lymphomatoid papulosis and other cutaneous lymphomas. A clinicopathologic, immunohistochemical, and molecular biological study of 13 cases
    Werner Kempf
    Kempf und Pfaltz Histologische Diagnostik, Seminarstrasse 1, CH 8042 Zürich, Switzerland
    Am J Surg Pathol 36:1021-9. 2012
  7. doi request reprint Classification of cutaneous lymphomas - an update
    Werner Kempf
    Kempf und Pfaltz, Histologische Diagnostik, University Hospital Zurich, Zurich, Switzerland
    Histopathology 56:57-70. 2010
  8. doi request reprint Detection of Merkel cell polyomavirus in epidermodysplasia-verruciformis-associated skin neoplasms
    K D Mertz
    Kempf and Pfaltz Histological Diagnostics, Research Unit, University Hospital Zurich, Zurich, Switzerland
    Dermatology 222:87-92. 2011
  9. ncbi request reprint Detection of clonal rearrangement of T-cell receptor genes in the diagnosis of primary cutaneous CD30 lymphoproliferative disorders
    Johannes Greisser
    Department of Dermatology, University Hospital, Zurich, Switzerland
    J Cutan Pathol 33:711-5. 2006
  10. doi request reprint Merkel cell polyomavirus is present in common warts and carcinoma in situ of the skin
    Kirsten D Mertz
    Kempf and Pfaltz Histological Diagnostics, Research Unit, Zurich, Switzerland
    Hum Pathol 41:1369-79. 2010

Detail Information

Publications60

  1. doi request reprint MUM1 expression in cutaneous CD30+ lymphoproliferative disorders: a valuable tool for the distinction between lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma
    W Kempf
    Kempf und Pfaltz, Histologische Diagnostik, Schaffhauserplatz 3, CH 8006 Zurich, Switzerland
    Br J Dermatol 158:1280-7. 2008
    ..MUM1 (Multiple Myeloma oncogene 1) is expressed in systemic ALCL and classical Hodgkin lymphoma. MUM1 expression has not been studied in detail in CD30+ lymphoproliferative disorders...
  2. doi request reprint Critical skin cancer in organ transplant recipients--a dermatopathological view
    Werner Kempf
    Kempf and Pfaltz, Histological Diagnostics, University Hospital Zurich, Seminarstrasse 1, Zurich, Switzerland
    Curr Probl Dermatol 43:18-35. 2012
    ..This review discusses the histopathological aspects of skin cancers in OTR, the impact of dermatopathological analysis on prognosis and understanding of the pathogenesis of these neoplasms...
  3. ncbi request reprint CD4/CD8 double negative mycosis fungoides with PD-1 (CD279) expression--a disease of follicular helper T-cells?
    Werner Kempf
    Kempf und Pfaltz, Histologische Diagnostik, Zurich, Switzerland
    Am J Dermatopathol 34:757-61. 2012
    ..Our observation may give an insight into the histogenesis of this unique MF variant and may also be of therapeutic significance because programmed death-1 may serve as a target for therapeutic intervention...
  4. doi request reprint Follicular lymphomatoid papulosis revisited: a study of 11 cases, with new histopathological findings
    Werner Kempf
    Kempf und Pfaltz, Histologische Diagnostik, Zurich, Switzerland
    J Am Acad Dermatol 68:809-16. 2013
    ..Follicular lymphomatoid papulosis (LyP) describes a variant of LyP with perifollicular infiltrates and some degree of folliculotropism of CD30(+) atypical lymphocytes. So far, only a few cases of follicular LyP have been described...
  5. doi request reprint Unilesional follicular mycosis fungoides: report of two cases with progression to tumor stage and review of the literature
    Werner Kempf
    Kempf und Pfaltz, Histologische Diagnostik, Zurich, Switzerland
    J Cutan Pathol 39:853-60. 2012
    ..Complete remission was achieved by local radiation therapy in both patients. The differential diagnoses, classification and implications for the treatment of unilesional FMF as well as the pertinent literature are discussed...
  6. doi request reprint Pityriasis lichenoides et varioliformis acuta with numerous CD30(+) cells: a variant mimicking lymphomatoid papulosis and other cutaneous lymphomas. A clinicopathologic, immunohistochemical, and molecular biological study of 13 cases
    Werner Kempf
    Kempf und Pfaltz Histologische Diagnostik, Seminarstrasse 1, CH 8042 Zürich, Switzerland
    Am J Surg Pathol 36:1021-9. 2012
    ....
  7. doi request reprint Classification of cutaneous lymphomas - an update
    Werner Kempf
    Kempf und Pfaltz, Histologische Diagnostik, University Hospital Zurich, Zurich, Switzerland
    Histopathology 56:57-70. 2010
    ..Recent changes in the terminology and staging, practical implications and future perspectives are discussed...
  8. doi request reprint Detection of Merkel cell polyomavirus in epidermodysplasia-verruciformis-associated skin neoplasms
    K D Mertz
    Kempf and Pfaltz Histological Diagnostics, Research Unit, University Hospital Zurich, Zurich, Switzerland
    Dermatology 222:87-92. 2011
    ..Among polyomaviruses, the novel Merkel cell polyomavirus (MCPyV) has been found in different epithelial skin neoplasias...
  9. ncbi request reprint Detection of clonal rearrangement of T-cell receptor genes in the diagnosis of primary cutaneous CD30 lymphoproliferative disorders
    Johannes Greisser
    Department of Dermatology, University Hospital, Zurich, Switzerland
    J Cutan Pathol 33:711-5. 2006
    ....
  10. doi request reprint Merkel cell polyomavirus is present in common warts and carcinoma in situ of the skin
    Kirsten D Mertz
    Kempf and Pfaltz Histological Diagnostics, Research Unit, Zurich, Switzerland
    Hum Pathol 41:1369-79. 2010
    ..Remarkably, some of the Merkel cell polyomavirus-positive common warts did not contain human papillomavirus. Furthermore, Merkel cell polyomavirus can be found in various skin neoplasms of the same individual...
  11. doi request reprint Angioinvasive lymphomatoid papulosis: a new variant simulating aggressive lymphomas
    Werner Kempf
    Kempf und Pfaltz, Histologische Diagnostik, Zurich, Switzerland
    Am J Surg Pathol 37:1-13. 2013
    ..This LyP variant should be distinguished from aggressive forms of angiocentric and angiodestructive and cytotoxic T-cell lymphomas. We propose the term LyP type E for this clinically and histologically unusual variant...
  12. ncbi request reprint Cutaneous malignant lymphomas: update 2006
    Gunter Burg
    Dept of Dermatology, University Hospital, Zurich, Switzerland
    J Dtsch Dermatol Ges 4:914-33. 2006
    ..Besides the classical options for therapy, there are new and "experimental" strategies, the efficacy of which has to be studied in clinical trials...
  13. ncbi request reprint Apoptosis in CD30-positive lymphoproliferative disorders of the skin
    Johannes Greisser
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Exp Dermatol 14:380-5. 2005
    ..Pro-apoptotic protein Bax is expressed at high levels in CD30+ CLPD and may play a crucial role in mediating apoptosis of tumour cells...
  14. ncbi request reprint Superficial radiotherapy for patients with basal cell carcinoma: recurrence rates, histologic subtypes, and expression of p53 and Bcl-2
    Beate Zagrodnik
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Cancer 98:2708-14. 2003
    ..In the current article, the authors report recurrence rates among patients with BCC after superficial radiotherapy as well as Bcl-2 and p53 expression levels stratified by BCC subtype...
  15. ncbi request reprint Primary cutaneous B-cell lymphomas - clinicopathological, prognostic and therapeutic characterisation of 54 cases according to the WHO-EORTC classification and the ISCL/EORTC TNM classification system for primary cutaneous lymphomas other than mycosis fun
    Philippa Golling
    Department of Dermatology, Cutaneous Lymphoma Study Group, University Hospital, Zurich, Switzerland
    Leuk Lymphoma 49:1094-103. 2008
    ..Surgical excision or radiotherapy is highly effective in pcMZL and pcFCL...
  16. doi request reprint Basal cell carcinoma in a series of renal transplant recipients: epidemiology and clinicopathologic features
    Kirsten D Mertz
    Kempf and Pfaltz Histological Diagnostics, Schaffhauserplatz 3, CH 8042 Zürich, Switzerland
    Int J Dermatol 49:385-9. 2010
    ..Basal cell carcinoma (BCC) is the most common malignancy among Caucasians worldwide. The risk of BCC is 10-16 times higher among immunosuppressed transplant recipients compared with the general population...
  17. ncbi request reprint The anti-MAGE antibody B57 as a diagnostic marker in melanocytic lesions
    Dmitry V Kazakov
    Unit of Dermatopathology, Department of Dermatology, University Hospital, Zurich, Switzerland
    Am J Dermatopathol 26:102-7. 2004
    ....
  18. ncbi request reprint Extracutaneous transformation into a high-grade lymphoma: a potential pitfall in the management of patients with Sézary syndrome
    Sonja Michaelis
    Department of Dermatology, University Hospital, Zurich, Switzerland
    Int J Dermatol 45:277-9. 2006
    ..Transformation into a high-grade lymphoma in cutaneous T-cell lymphoma (CTCL) occurs in approximately 25% of cases and is associated with an aggressive clinical course...
  19. ncbi request reprint Hepatitis C and G viruses in B-cell lymphomas of the skin
    Sonja Michaelis
    Unit of Dermatopathology, Department of Dermatology, University Hospital, Zurich, Switzerland
    J Cutan Pathol 30:369-72. 2003
    ..Most studies were performed in patients with known HCV infection, but the overall frequency of HCV- and HGV-RNA in tumoral tissue of primary cutaneous B-cell lymphomas (CBCLs) is unknown...
  20. ncbi request reprint Micronodular Kaposi's sarcoma - a new variant of classic-sporadic Kaposi's sarcoma
    Werner Kempf
    Department of Dermatology, Institute for Clinical Pathology, University Hospital Zurich, Zurich, Switzerland
    Dermatology 208:255-8. 2004
    ..We propose the term 'micronodular KS' for this unusual clinical variant of KS mimicking capillary hemangioma...
  21. ncbi request reprint WHO/EORTC classification of cutaneous lymphomas 2005: histological and molecular aspects
    Gunter Burg
    Department of Dermatology, University Hospital Zurich, Switzerland
    J Cutan Pathol 32:647-74. 2005
    ..These findings always have to be interpreted in the context of the clinical features and biologic behavior...
  22. ncbi request reprint Multilineage progression of genetically unstable tumor subclones in cutaneous T-cell lymphoma
    Albert Rübben
    Department of Dermatology, Universitatsspital Zurich, Zurich, Switzerland
    Exp Dermatol 13:472-83. 2004
    ..Our results suggest that CTCL may evolve by multilineage progression and that tumor subclones in MF can be detected in early disease stages by mutation analysis of microsatellite DNA obtained from multiple microdissected areas...
  23. doi request reprint Clonality in sarcoidosis, granuloma annulare, and granulomatous mycosis fungoides
    Katrin Pfaltz
    Kempf and Pfaltz Histological Diagnostics, Zurich, Switzerland
    Am J Dermatopathol 33:659-62. 2011
    ..The analysis of T-cell clonality is a useful diagnostic adjunct in the differentiation between sarcoidosis and GA from granulomatous CTCLs...
  24. doi request reprint Skin cancer in organ transplant recipients
    Werner Kempf
    Kempf and Pfaltz Histological Diagnostics, Zurich, Switzerland
    Pathobiology 80:302-9. 2013
    ..This review discusses the clinical and histopathological aspects of skin cancers in OTR, the impact of dermatopathological analysis on prognosis and the understanding of the pathogenesis of these neoplasms. ..
  25. ncbi request reprint Study of HHV-8 DNA sequences in archival biopsies from lesional skin of Kaposi's sarcoma, various mesenchymal tumors and related reactive conditions
    Dmitry V Kazakov
    Department of Dermatology, University Hospital, Zurich, Switzerland
    J Cutan Pathol 29:279-81. 2002
    ..The aim of the study was to ascertain the value of identification of HHV-8 viral DNA sequences in routinely processed, formalin-fixed, paraffin-embedded tissues for the diagnosis of Kaposi's sarcoma and other mesenchymal tumors...
  26. ncbi request reprint Angiolymphoid hyperplasia with eosinophilia: evidence for a T-cell lymphoproliferative origin
    Werner Kempf
    Department of Dermatology, University Hospital Zurich, Switzerland
    Hum Pathol 33:1023-9. 2002
    ..These data suggest that ALHE or a subset of ALHE cases harboring a clonal T-cell population may represent a T-cell lymphoproliferative disorder of a benign or low-grade malignant nature...
  27. ncbi request reprint Topical photodynamic therapy in the treatment of actinic keratoses and Bowen's disease in transplant recipients
    Galya Dragieva
    Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland
    Transplantation 77:115-21. 2004
    ..Topical photodynamic therapy (PDT) has been proven to be an effective treatment for AK and BD in immunocompetent patients, but no prospective trials in immunocompromised TR have been performed so far...
  28. ncbi request reprint Topical and systemic retinoid therapy for cutaneous T-cell lymphoma
    Werner Kempf
    Department of Dermatology, University Hospital, Gloriastrasse 31, CH 8091, Zurich, Switzerland
    Hematol Oncol Clin North Am 17:1405-19. 2003
    ..In addition, new agonists of RAR and RXR, either selective or pan agonists, will become available and will enlarge the spectrum of vitamin A analogs that have antitumoral properties...
  29. doi request reprint Primary cutaneous CD8(+) small- to medium-sized lymphoproliferative disorder in extrafacial sites: clinicopathologic features and concept on their classification
    Werner Kempf
    Kempf und Pfaltz Histologische Diagnostik, Zurich, Switzerland
    Am J Dermatopathol 35:159-66. 2013
    ....
  30. ncbi request reprint Intra-lesional low-dose interferon alpha2a therapy for primary cutaneous marginal zone B-cell lymphoma
    Antonio Cozzio
    Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland
    Leuk Lymphoma 47:865-9. 2006
    ..All other patients remained free of disease. Thus, intra-lesional IFNalpha2a may represent a valuable alternative to surgery and radiotherapy as first-line treatment of pcMZL...
  31. doi request reprint Inflammatory monocytes are a reservoir for Merkel cell polyomavirus
    Kirsten D Mertz
    Kempf and Pfaltz Histological Diagnostics, Research Unit, Zurich, Switzerland
    J Invest Dermatol 130:1146-51. 2010
    ..This points to intervention strategies to contain MCPyV. Moreover, blood or urine tests may serve as ancillary tests to confirm MCPyV infection in a clinical setting...
  32. ncbi request reprint Cutaneous lymphomas and pseudolymphomas: newly described entities
    Dmitry V Kazakov
    Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland
    Recent Results Cancer Res 160:283-93. 2002
    ..In the context of pseudolymphomas, cutaneous follicular lymphoid hyperplasia with monotypic plasma cells, pleomorphic reactions in molluscum contagiosum, and CD30+ reactions to parapoxvirus are discussed...
  33. ncbi request reprint Proliferation of CD30+ T-helper 2 lymphoma cells can be inhibited by CD30 receptor cross-linking with recombinant CD30 ligand
    Jörg Willers
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Clin Cancer Res 9:2744-54. 2003
    ..Proliferation and apoptosis of cultured cells were measured by 5-bromo-2-desoxyuridine and propidium iodine incorporation...
  34. doi request reprint Primary cutaneous B-cell lymphomas
    Werner Kempf
    Department of Dermatology, University Hospital Zurich, Switzerland
    J Dtsch Dermatol Ges 10:12-22; quiz 23. 2012
    ..Clinico-pathologic correlation, histology with immunohistochemical profile and genotyping as well as staging examinations are crucial diagnostic elements in the work-up of CBCL...
  35. doi request reprint Spindle-cell variant of primary cutaneous follicle center lymphoma spreading to the hepatobiliary tree, mimicking Klatskin tumor
    Sima Rozati
    Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland
    J Cutan Pathol 40:56-60. 2013
    ..On the basis of the sparse published data on spindle-cell morphology of pcBCL, this growth pattern should elicit awareness of an increased risk of systemic involvement in the otherwise indolent pcFCL...
  36. ncbi request reprint Granulomatous mycosis fungoides and granulomatous slack skin: a multicenter study of the Cutaneous Lymphoma Histopathology Task Force Group of the European Organization For Research and Treatment of Cancer (EORTC)
    Werner Kempf
    Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, CH 8091 Zurich, Switzerland
    Arch Dermatol 144:1609-17. 2008
    ..We studied 19 patients with granulomatous CTCLs to further characterize the clinicopathological, therapeutic, and prognostic features...
  37. ncbi request reprint Imiquimod induces complete clearance of a PUVA-resistant plaque in mycosis fungoides
    Reinhard Dummer
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Dermatology 207:116-8. 2003
    ..However, the plaque on the face was PUVA resistant. Local imiquimod treatment resulted in the complete clearance of the plaque. The patient has now been in complete remission for 12 months...
  38. ncbi request reprint CD30+ lymphoproliferative disorders: histopathology, differential diagnosis, new variants, and simulators
    Werner Kempf
    Department of Dermatology, University Hospital Zurich, Switzerland
    J Cutan Pathol 33:58-70. 2006
    ..The term CD30+ pseudolymphoma is proposed to designate inflammatory processes with CD30+ T cells. The final diagnosis of CD30+ LPD is based on a synthesis of clinical, histologic, phenotypic, and molecular genetic findings...
  39. doi request reprint Pre- and posttransplant management of solid organ transplant recipients: risk-adjusted follow-up
    Bahar Shafaeddin Schreve
    Dermatologische Klinik, Universitatsspital Zurich, Gloriastrasse 31, Zurich, Switzerland
    Curr Probl Dermatol 43:57-70. 2012
    ..The dermatological follow-up of SOTR should be integrated into the comprehensive posttransplant care...
  40. doi request reprint Borrelia in granuloma annulare, morphea and lichen sclerosus: a PCR-based study and review of the literature
    Therese Zollinger
    Kempf und Pfaltz Histologische Diagnostik, Zurich, Switzerland
    J Cutan Pathol 37:571-7. 2010
    ..Thus, we examined skin biopsies of morphea, GA and LSA by PCR to assess the prevalence of Borrelia DNA in an endemic area and to compare our results with data in the literature...
  41. doi request reprint Primary cutaneous anaplastic large cell lymphoma with angioinvasive features and cytotoxic phenotype: a rare lymphoma variant within the spectrum of CD30+ lymphoproliferative disorders
    Werner Kempf
    Kempf und Pfaltz, Histologische Diagnostik, University Hospital, Zurich, Switzerland
    Dermatology 227:346-52. 2013
    ..Primary cutaneous anaplastic large cell lymphoma (PCALCL) presents with solitary or grouped exophytic tumors and cohesive infiltrates of large CD30+ T cells...
  42. doi request reprint Immunohistochemical dual staining as an adjunct in assessment of mitotic activity in melanoma
    Kristian Ikenberg
    Kempf and Pfaltz Histological Diagnostics, Zurich, Switzerland
    J Cutan Pathol 39:324-30. 2012
    ..The detection of a single mitotic figure changes the tumor stage in thin melanoma. We sought to address the value of a dual staining to facilitate the determination of the mitotic rate and to assign the mitotic activity to melanocytes...
  43. ncbi request reprint Nephrogenic fibrosing dermopathy treated with extracorporeal photopheresis
    Severin Lauchli
    Department of Dermatology, University Hospital, Zurich, Switzerland
    Dermatology 208:278-80. 2004
    ..Two years after transplantation, she developed sclerodermiform brownish plaques on her extremities. The induration improved significantly after 4 cycles of extracorporeal photopheresis...
  44. ncbi request reprint Primary cutaneous plasmacytoma: a clinicopathological study of two cases with a long-term follow-up and review of the literature
    Dmitry V Kazakov
    Department of Dermatology, University Hospital, Zurich, Switzerland
    J Cutan Pathol 29:244-8. 2002
    ..The disease is rare with only 30 cases reported so far...
  45. doi request reprint Necrotizing infundibular crystalline folliculitis: a clinicopathological study
    Natalja Denisjuk
    Kempf and Pfaltz, Histological Diagnostics, Zurich, Switzerland
    J Am Acad Dermatol 66:823-6. 2012
    ..There are only very few data published about this disorder of unknown origin...
  46. pmc EORTC, ISCL, and USCLC consensus recommendations for the treatment of primary cutaneous CD30-positive lymphoproliferative disorders: lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma
    Werner Kempf
    Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
    Blood 118:4024-35. 2011
    ..The recommendations represent the state-of-the-art management of CD30(+) LPDs and include definitions for clinical endpoints as well as response criteria for future clinical trials in CD30(+) LPDs...
  47. doi request reprint A rare case of atypical cellular neurothekeoma in a 68-year-old woman
    Kirsten D Mertz
    Kempf and Pfaltz Histological Diagnostics, Zurich, Switzerland
    J Cutan Pathol 36:1210-4. 2009
    ..Our report contributes to a better characterization of the clinical and morphologic features of atypical cellular neurothekeoma...
  48. ncbi request reprint From inflammation to neoplasia: new concepts in the pathogenesis of cutaneous lymphomas
    Gunter Burg
    Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland
    Recent Results Cancer Res 160:271-80. 2002
    ..g. environmental foreign antigens, bacterial superantigen, and/or endogenous factors, e.g. autocrine cytokine loops, CD40/CD40L and B7/CD28 interaction...
  49. ncbi request reprint Successful treatment of recalcitrant chronic actinic dermatitis with tacrolimus
    Christian Schuster
    Department of Dermatology, University Hospital Zurich, Switzerland
    Dermatology 209:325-8. 2004
    ..We present a case of chronic actinic dermatitis responding well to topically applied tacrolimus (Protopic) in combination with chemical and physical UV protection...
  50. ncbi request reprint C3d immunohistochemistry on formalin-fixed tissue is a valuable tool in the diagnosis of bullous pemphigoid of the skin
    Katrin Pfaltz
    Kempf and Pfaltz Histological Diagnostics, CH 8042 Zürich, Switzerland
    J Cutan Pathol 37:654-8. 2010
    ..Direct immunofluorescence (DIF) testing is an important procedure in the diagnosis of autoimmune bullous dermatoses. We investigated the expression of C3d in formalin-fixed, paraffin-embedded tissue of autoimmune bullous dermatoses...
  51. ncbi request reprint Pediatric CD8+CD56+ Non-poikilodermatous Mycosis Fungoides: Case Report and Review of the Literature
    Werner Kempf
    Kempf und Pfaltz, Histologische Diagnostik, Zurich, Switzerland Department of Pathology, Faculty of Medicine in Pilsen, Charles University in Prague, Prague, Czech Republic and Department of Dermatology, University of Munster, Munster, Germany
    Am J Dermatopathol 36:598-602. 2014
    ..The differential diagnosis of CD8 epidermotropic lymphocytic infiltrates in children is discussed, and the cases of CD8CD56 MF reported in the literature are reviewed. ..
  52. doi request reprint Cutaneous lymphomas: an update. Part 1: T-cell and natural killer/t-cell lymphomas and related conditions
    Werner Kempf
    Dermatopathologist and Dermatologist, Kempf und Pfaltz, Histologische Diagnostik, Zurich, Switzerland Professor, Department of Dermatology, University Hospital Zurich, Switzerland Dermatopathologist and Dermatologist, Professor, Department of Pathology, Medical Faculty in Pilsen, Charles University, Prague, Czech Republic and Dermatopathologist and Dermatologist, Faculty Member, Department of Dermatology, University Hospital Zurich, Switzerland
    Am J Dermatopathol 36:105-23. 2014
    ..Clinicopathologic correlation is mandatory for the diagnosis of primary CLs. Analysis of genetic and epigenetic alterations in CLs revealed new diagnostic markers and putative targets for therapy of aggressive forms of CLs...
  53. ncbi request reprint CO2 laser treatment of warts in immunosuppressed patients
    Severin Lauchli
    Department of Dermatology, University Hospital, Zurich, Switzerland
    Dermatology 206:148-52. 2003
    ..Furthermore, the incidence of nonmelanoma skin cancer is clearly elevated in this patient group and human papillomavirus is most likely to play a causal role in these neoplasms...
  54. ncbi request reprint HistoClinC: a Web-based telemedicine application for clinicopathologic correlations in dermatopathology
    Werner Kempf
    Department of Dermatology, University Hospital, Zurich, Switzerland
    Curr Probl Dermatol 32:213-20. 2003
  55. doi request reprint Lobular panniculitis due to Borrelia burgdorferi infection mimicking subcutaneous panniculitis-like T-cell lymphoma
    Werner Kempf
    Kempf und Pfaltz, Histologische Diagnostik, Zurich, Switzerland
    Am J Dermatopathol 35:e30-3. 2013
    ..B. burgdorferi etiology was proven by positive polymerase chain reaction and serology and positive response to antibiotics...
  56. ncbi request reprint HLA-G protein up-regulation in primary cutaneous lymphomas is associated with interleukin-10 expression in large cell T-cell lymphomas and indolent B-cell lymphomas
    Mirjana Urosevic
    Department of Dermatology, University Hospital Zurich, Switzerland
    Blood 99:609-17. 2002
    ..001). HLA-G up-regulation together with IL-10 expression in CL might additionally contribute to the evasion of immunosurveillance and facilitate the transition from low- to high-grade lymphomas...
  57. doi request reprint Spitzoid melanoma and micrometastases in two lymph node regions: a critical situation
    Alexander A Navarini
    Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, 8091 Zurich, Switzerland
    Eur J Dermatol 21:229-33. 2011
    ..Treatment decisions for atypical Spitz tumors are a major medical and ethical challenge due to the limited available data...
  58. ncbi request reprint Two Cases of Primary Cutaneous Lymphoma With a γ/δ+ Phenotype and an Indolent Course: Further Evidence of Heterogeneity of Cutaneous γ/δ+ T-Cell Lymphomas
    Werner Kempf
    Kempf und Pfaltz Histologische Diagnostik, Zurich, Switzerland Department of Pathology, Faculty of Medicine in Pilsen, Charles University in Prague, Prague, Czech Republic Dermatology Practice, Brugg, Switzerland and Department of Dermatology, University of Cologne, Cologne, Germany
    Am J Dermatopathol 36:570-7. 2014
    ..These cases corroborate the view that expression of a γ/δ+ phenotype in cutaneous T-cell lymphomas per se does not portend a worse prognosis and that CGD-TCL may represent a clinically and prognostically heterogeneous group. ..
  59. doi request reprint Cutaneous lymphomas: an update. Part 2: B-cell lymphomas and related conditions
    Werner Kempf
    Kempf und Pfaltz, Histologische Diagnostik, Zurich, Switzerland Professor, Department of Dermatology, University Hospital Zurich, Zurich, Switzerland Professor, Department of Pathology, Medical Faculty in Pilsen, Pilsen, Charles University in Prague, Czech Republic and Doctor, Department of Dermatology, Klinikum Hildesheim GmbH, Hildesheim, Germany
    Am J Dermatopathol 36:197-208; quiz 209-10. 2014
    ....
  60. pmc Disseminated molluscum contagiosum in a HIV-positive child. Improvement after therapy with 5% imiquimod
    Martin Theiler
    Department of Dermatology, University Hospital, Zurich, Switzerland
    J Dermatol Case Rep 5:19-23. 2011
    ..With the emergence of HIV/AIDS, a new patient group at risk has been identified with often extensive skin involvement and recalcitrant disease...