Affiliation: Friedrich Miescher Institute
- Neurofibrosarcoma-derived Schwann cells overexpress platelet-derived growth factor (PDGF) receptors and are induced to proliferate by PDGF BBA Badache
Department of Cell Biology, Neurobiology and Anatomy, Loyola University Medical Center, Chicago, Illinois, USA
J Cell Physiol 177:334-42. 1998..Therefore, aberrant expression of growth factor receptors by Schwann cells, such as the PDGF receptors, could represent an important step in the process leading to Schwann cell hyperplasia in NF1...
- Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cellsA Badache
Friedrich Miescher Institute, Basel, Switzerland
Cancer Res 61:383-91. 2001..Cooperation between IL-6 and the EGF receptor in T47D breast carcinoma cells illustrates how a combination of multiple stimuli, either exogenous or endogenous, may result in synergistic cellular responses...
- An essential role for Src kinase in ErbB receptor signaling through the MAPK pathwayM A Olayioye
Friedrich Miescher Institute, Basel, CH-4002, Switzerland
Exp Cell Res 267:81-7. 2001..Thus, ErbB signaling requires the engagement of a novel Src-dependent route to MAPK, to trigger its rapid activation and subsequent efficient stimulation of transcription...
- The ErbB receptor tyrosine family as signal integratorsN E Hynes
Friedrich Miescher Institute, PO Box 2543, CH 4002 Basel, Switzerland
Endocr Relat Cancer 8:151-9. 2001..Cross-regulation of ErbB RTKs and cytokines receptors represents another mechanism for controlling and enhancing tumor cell proliferation...