Christian Starkenmann

Summary

Affiliation: Firmenich SA
Country: Switzerland

Publications

  1. ncbi request reprint Analysis of a model reaction system containing cysteine and (E)-2-methyl-2-butenal, (E)-2-hexenal, or mesityl oxide
    Christian Starkenmann
    Firmenich S A 1, route des Jeunes, 1211 Geneva 8, Switzerland
    J Agric Food Chem 51:7146-55. 2003
  2. ncbi request reprint 5α-Androst-16-en-3α-ol β-D-glucuronide, precursor of 5α-androst-16-en-3α-ol in human sweat
    Christian Starkenmann
    Firmenich SA, Corporate R and D Division, 1 Route des Jeunes, P O Box 239, CH 1211 Geneva 8, phone 41 22 7803477 fax 41 22 7803334
    Chem Biodivers 10:2197-208. 2013
  3. doi request reprint Four windows on modern science in flavor and fragrance chemistry at Firmenich
    Christian Starkenmann
    Firmenich SA, Corporate R and D Division, P O Box 239, CH 1211 Geneva 8, Switzerland
    Chimia (Aarau) 66:343-4. 2012
  4. doi request reprint Nonvolatile S-alk(en)ylthio-L-cysteine derivatives in fresh onion (Allium cepa L. cultivar)
    Christian Starkenmann
    Corporate R and D Division, Firmenich SA, P O Box 239, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 59:9457-65. 2011
  5. ncbi request reprint Exploring natural products for new taste sensations
    Christian Starkenmann
    Firmenich SA, Corporate R and D Division, P O Box 239, CH 1211 Geneva 8
    Chimia (Aarau) 65:407-10. 2011
  6. doi request reprint New cysteine-S-conjugate precursors of volatile sulfur compounds in bell peppers (Capsicum annuum L. cultivar)
    Christian Starkenmann
    Corporate R and D Division, Firmenich SA, P O Box 239, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 59:3358-65. 2011
  7. doi request reprint Hemisynthesis of dihydroumbellulols from umbellulone: new cooling compounds
    Christian Starkenmann
    Corporate R and D Division, Firmenich SA, PO Box 239, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 59:677-83. 2011
  8. ncbi request reprint Taste contribution of (R)-strombine to dried scallop
    Christian Starkenmann
    Corporate R and D Division, Firmenich SA, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 57:7938-43. 2009
  9. doi request reprint Olfactory perception of cysteine-S-conjugates from fruits and vegetables
    Christian Starkenmann
    Corporate R and D Division, Firmenich SA, P O Box 239, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 56:9575-80. 2008
  10. ncbi request reprint Structure elucidation of a pungent compound in black cardamom: Amomum tsao-ko Crevost et Lemarié (Zingiberaceae)
    Christian Starkenmann
    Firmenich SA, Corporate R and D Division, Geneva, Switzerland
    J Agric Food Chem 55:10902-7. 2007

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Analysis of a model reaction system containing cysteine and (E)-2-methyl-2-butenal, (E)-2-hexenal, or mesityl oxide
    Christian Starkenmann
    Firmenich S A 1, route des Jeunes, 1211 Geneva 8, Switzerland
    J Agric Food Chem 51:7146-55. 2003
    ..Addition of cysteine to mesityl oxide (16), at pH 8, followed by reduction with NaBH(4) furnished (R)-S-(3-hydroxy-1,1-dimethylbutyl)cysteine (3) and the new compound (3R)-hexahydro-5,7,7-trimethyl-1,4-thiazepine-3-carboxylic acid (18)...
  2. ncbi request reprint 5α-Androst-16-en-3α-ol β-D-glucuronide, precursor of 5α-androst-16-en-3α-ol in human sweat
    Christian Starkenmann
    Firmenich SA, Corporate R and D Division, 1 Route des Jeunes, P O Box 239, CH 1211 Geneva 8, phone 41 22 7803477 fax 41 22 7803334
    Chem Biodivers 10:2197-208. 2013
    ....
  3. doi request reprint Four windows on modern science in flavor and fragrance chemistry at Firmenich
    Christian Starkenmann
    Firmenich SA, Corporate R and D Division, P O Box 239, CH 1211 Geneva 8, Switzerland
    Chimia (Aarau) 66:343-4. 2012
    ..The objective was to stimulate young students to choose sciences. The challenges in the discovery, synthesis, or extraction of new molecules were presented, as well as the structure-activity relationships of human odorant receptors...
  4. doi request reprint Nonvolatile S-alk(en)ylthio-L-cysteine derivatives in fresh onion (Allium cepa L. cultivar)
    Christian Starkenmann
    Corporate R and D Division, Firmenich SA, P O Box 239, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 59:9457-65. 2011
    ..Whereas the plant enzyme efficiently transforms S-alk(en)yl-S-oxo-L-cysteine, mouth bacteria are responsible for the transformation of S-alk(en)ylthio-L-cysteine...
  5. ncbi request reprint Exploring natural products for new taste sensations
    Christian Starkenmann
    Firmenich SA, Corporate R and D Division, P O Box 239, CH 1211 Geneva 8
    Chimia (Aarau) 65:407-10. 2011
    ..1.0]hexan-2-ol, named dihydroumbellulol, a new cooling compound obtained by hemi-synthesis from umbellulone extracted from Umbellularia californica Nutt...
  6. doi request reprint New cysteine-S-conjugate precursors of volatile sulfur compounds in bell peppers (Capsicum annuum L. cultivar)
    Christian Starkenmann
    Corporate R and D Division, Firmenich SA, P O Box 239, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 59:3358-65. 2011
    ..A quantitative estimation based on external calibration curves, established by UPLC-MS ESI(+) in selected reaction monitoring mode, showed that cysteine-S-conjugates were present at concentrations in the range of 1 to 100 μg/kg (±20%)...
  7. doi request reprint Hemisynthesis of dihydroumbellulols from umbellulone: new cooling compounds
    Christian Starkenmann
    Corporate R and D Division, Firmenich SA, PO Box 239, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 59:677-83. 2011
    ..In addition, a previously unreported compound was discovered, (-)-(1R)-1-isopropyl-4-methylenebicyclo[3.1.0]hexan-2-one...
  8. ncbi request reprint Taste contribution of (R)-strombine to dried scallop
    Christian Starkenmann
    Corporate R and D Division, Firmenich SA, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 57:7938-43. 2009
    ..R) and (S)-strombine were prepared, and a sensory analysis with 47 judges demonstrated that the taste thresholds were 0.5 g/L for (R)-strombine and 0.7 g/L for (S)-strombine. The sensory attributes were described as salty and umami...
  9. doi request reprint Olfactory perception of cysteine-S-conjugates from fruits and vegetables
    Christian Starkenmann
    Corporate R and D Division, Firmenich SA, P O Box 239, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 56:9575-80. 2008
    ..The cysteine- S-conjugates are transformed in free thiol by anaerobes. The mouth acts as a reactor, adding another dimension to odor perception, and saliva modulates flavors by trapping free thiols...
  10. ncbi request reprint Structure elucidation of a pungent compound in black cardamom: Amomum tsao-ko Crevost et Lemarié (Zingiberaceae)
    Christian Starkenmann
    Firmenich SA, Corporate R and D Division, Geneva, Switzerland
    J Agric Food Chem 55:10902-7. 2007
    ....
  11. ncbi request reprint Volatile organic sulfur-containing constituents in Poncirus trifoliata (L.) Raf. (Rutaceae)
    Christian Starkenmann
    Firmenich SA, Corporate R and D Division, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 55:4511-7. 2007
    ..No cysteine-S-conjugates were detected in the fruit juice...
  12. ncbi request reprint How cysteine reacts with citral: an unexpected reaction of beta,beta-disubstituted acroleins with cysteine leading to hexahydro-1,4-thiazepines
    Christian Starkenmann
    R and D Division, Firmenich SA, P O Box 239, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 53:9244-8. 2005
    ..The adduct 6 obtained from citral, under acidic conditions, reacted further to give the new bicyclic compound 8...
  13. ncbi request reprint Comparison of volatile constituents of Persicaria odorata(Lour.) Soják (Polygonum odoratum Lour.) and Persicaria hydropiper L. Spach (Polygonum hydropiper L.)
    Christian Starkenmann
    Corporate R and D Division, Firmenich SA, P O Box 239, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 54:3067-71. 2006
    ..Spach (formerly Polygonum hydropiper L., synonym water pepper) is produced by polygodial, a 1,4-dialdehyde derived from drimane terpenoids. We also identified polygodial as the active pungent compound in P. odorata (Lour.) Soják...
  14. ncbi request reprint Combinatorial synthesis by nature: volatile organic sulfur-containing constituents of Ruta chalepensis L
    Sina Escher
    Firmenich SA, Corporate R and D Division, P O Box 239, CH 1211 Geneva 8
    Chem Biodivers 3:943-57. 2006
    ..The relative and absolute configurations of the four stereoisomers of 4-methyl-3-sulfanylhexan-1-ol (5) were established by stereoselective synthesis. The natural isomers consisted of a 65 : 35 mixture of (3R,4S)-5 and (3S,4S)-5...
  15. doi request reprint Gender-specific differences between the concentrations of nonvolatile (R)/(S)-3-methyl-3-sulfanylhexan-1-Ol and (R)/(S)-3-hydroxy-3-methyl-hexanoic acid odor precursors in axillary secretions
    Myriam Troccaz
    Firmenich SA, Corporate R and D Division, PO Box 239, CH 1211 Geneva 8, Switzerland
    Chem Senses 34:203-10. 2009
    ..Sweat samples having the highest sulfur intensity were also found to be the most intense and the most unpleasant...
  16. ncbi request reprint Identification of the precursor of (S)-3-methyl-3-sulfanylhexan-1-ol, the sulfury malodour of human axilla sweat
    Christian Starkenmann
    Firmenich SA, Analysis and Perception Department, Corporate R and D Division, Geneva
    Chem Biodivers 2:705-16. 2005
    ..epidermidis were less efficient in cleaving Cys-Gly-(S)-conjugate 12 to form the corresponding thiol 3. Incubation of glutathione-(S)-conjugate 11 never led to the formation of 3 under the experimental conditions employed...
  17. ncbi request reprint 3-Methyl-3-sulfanylhexan-1-ol as a major descriptor for the human axilla-sweat odour profile
    Myriam Troccaz
    Firmenich SA, Corporate R and D Division, P O Box 239, CH 1211 Geneva 8
    Chem Biodivers 1:1022-35. 2004
    ..The (S)-form was found to be the major enantiomer (75%)...
  18. ncbi request reprint Volatile constituents of Semnostachya menglaensis Tsui
    Regula Naef
    Corporate R and D Division, Firmenich SA, P O Box 239, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 53:9161-4. 2005
    ..9%), 1-(1,4,5,6-tetrahydro-2-pyridyl)-1-ethanone (4.8%), 1-(2-piperidyl)-1-propanone (5.2%), 1-octen-3-ol (3.2%), 1-octen-3-one (1.9%), and 3-octanol and 1-(2-pyridyl)-1-propanone in trace amounts...
  19. ncbi request reprint Chiral multidimensional gas chromatography (MDGC) and chiral GC-olfactometry with a double-cool-strand interface: application to malodors
    Frederic Begnaud
    Firmenich SA, Corporate R and D Division, CH 1211 Geneva 8, Switzerland
    Chem Biodivers 3:150-60. 2006
    ..The enantiomer ratio of the sweat malodor 1 was determined as (S)/(R) 3 : 1, and the dominating (S)-isomer was shown to largely impart its specific character to the overall odor of the sweat extract...
  20. doi request reprint Qualitative and quantitative analysis of volatile constituents from latrines
    Jianming Lin
    Firmenich SA, Corporate R and D Division, P O Box 239, CH 1211 Geneva 8, Switzerland
    Environ Sci Technol 47:7876-82. 2013
    ....
  21. doi request reprint Volatile composition of oyster leaf (Mertensia maritima (L.) Gray)
    Estelle Delort
    Corporate R and D Division, Firmenich SA, P O Box 239, CH 1211 Geneva 8, Switzerland
    J Agric Food Chem 60:11681-90. 2012
    ..After evaluation of freshly prepared reference samples, these compounds were confirmed to be reminiscent of the oyster-like marine notes perceived in the tasting of cut leaves...