Michel Schalk

Summary

Affiliation: Firmenich SA
Country: Switzerland

Publications

  1. pmc Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae
    Gionata Scalcinati
    Department of Chemical and Biological Engineering, Chalmers University of Technology, SE 412 96, Goteborg, Sweden
    Microb Cell Fact 11:117. 2012
  2. doi request reprint Toward a biosynthetic route to sclareol and amber odorants
    Michel Schalk
    Biotechnology Department, Corporate R and D Division, Firmenich SA, Geneva CH 1211, Switzerland
    J Am Chem Soc 134:18900-3. 2012
  3. pmc Functional annotation, genome organization and phylogeny of the grapevine (Vitis vinifera) terpene synthase gene family based on genome assembly, FLcDNA cloning, and enzyme assays
    Diane M Martin
    Michael Smith Laboratories, University of British Columbia, 2185 East Mall, Vancouver, B C, V6T 1Z4, Canada
    BMC Plant Biol 10:226. 2010
  4. pmc Whole genome sequencing of Saccharomyces cerevisiae: from genotype to phenotype for improved metabolic engineering applications
    Jose Manuel Otero
    Department of Chemical and Biological Engineering, Chalmers University of Technology, SE 41296 Gothenburg, Sweden
    BMC Genomics 11:723. 2010
  5. ncbi request reprint The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases
    Fabienne Deguerry
    Firmenich SA, Biotechnology Department, Corporate R and D Division, P O Box 239, CH 1211 Geneva 8, Switzerland
    Arch Biochem Biophys 454:123-36. 2006

Collaborators

  • Gionata Scalcinati
  • Laurent Daviet
  • Jens Nielsen
  • Diane M Martin
  • Jose Manuel Otero
  • Anthony Clark
  • Fabienne Deguerry
  • Verena Siewers
  • Siavash Partow
  • Steven T Lund
  • Wanwipa Vongsangnak
  • Mohammad A Asadollahi
  • Omid Toub
  • Jerome Maury
  • Jörg Bohlmann
  • Sébastien Aubourg
  • Loïc Barlocher
  • Magne Osterås
  • Roberto Olivares-Hernandes
  • Laurent Farinelli
  • Marina B Schouwey
  • Laurence Pastore
  • Shuiqin Wu
  • Joseph Chappell

Detail Information

Publications5

  1. pmc Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae
    Gionata Scalcinati
    Department of Chemical and Biological Engineering, Chalmers University of Technology, SE 412 96, Goteborg, Sweden
    Microb Cell Fact 11:117. 2012
    ..The hydrocarbon α-santalene is a precursor of sesquiterpenes with relevant commercial applications. Here, we construct an efficient Saccharomyces cerevisiae cell factory for α-santalene production...
  2. doi request reprint Toward a biosynthetic route to sclareol and amber odorants
    Michel Schalk
    Biotechnology Department, Corporate R and D Division, Firmenich SA, Geneva CH 1211, Switzerland
    J Am Chem Soc 134:18900-3. 2012
    ..5 g/L in high-cell-density fermentation. Our work provides a basis for the development of an alternative, sustainable, and cost-efficient route to sclareol and other diterpene analogues...
  3. pmc Functional annotation, genome organization and phylogeny of the grapevine (Vitis vinifera) terpene synthase gene family based on genome assembly, FLcDNA cloning, and enzyme assays
    Diane M Martin
    Michael Smith Laboratories, University of British Columbia, 2185 East Mall, Vancouver, B C, V6T 1Z4, Canada
    BMC Plant Biol 10:226. 2010
    ....
  4. pmc Whole genome sequencing of Saccharomyces cerevisiae: from genotype to phenotype for improved metabolic engineering applications
    Jose Manuel Otero
    Department of Chemical and Biological Engineering, Chalmers University of Technology, SE 41296 Gothenburg, Sweden
    BMC Genomics 11:723. 2010
    ..The exact genetic modification or resulting genotype that leads to the improved phenotype is often not identified or understood to enable further metabolic engineering...
  5. ncbi request reprint The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases
    Fabienne Deguerry
    Firmenich SA, Biotechnology Department, Corporate R and D Division, P O Box 239, CH 1211 Geneva 8, Switzerland
    Arch Biochem Biophys 454:123-36. 2006
    ....