Jane Durga

Summary

Country: Switzerland

Publications

  1. ncbi Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial
    Jane Durga
    Division of Human Nutrition, Wageningen University, 6700 EV Wageningen, Netherlands
    Lancet 369:208-16. 2007
  2. ncbi Effects of folic acid supplementation on hearing in older adults: a randomized, controlled trial
    Jane Durga
    Wageningen University and Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    Ann Intern Med 146:1-9. 2007
  3. ncbi Association of folate with hearing is dependent on the 5,10-methylenetetrahdyrofolate reductase 677C-->T mutation
    Jane Durga
    Division of Human Nutrition, Wageningen University, P O Box 8129, 6700 EV Wageningen, The Netherlands
    Neurobiol Aging 27:482-9. 2006
  4. doi Effect of 3 y of folic acid supplementation on the progression of carotid intima-media thickness and carotid arterial stiffness in older adults
    Jane Durga
    Division of Human Nutrition, Wageningen University, Wageningen, Netherlands
    Am J Clin Nutr 93:941-9. 2011
  5. ncbi Folate and the methylenetetrahydrofolate reductase 677C-->T mutation correlate with cognitive performance
    Jane Durga
    Division of Human Nutrition, Wageningen University, 6700 EV Wageningen, The Netherlands
    Neurobiol Aging 27:334-43. 2006
  6. doi Hemochromatosis (HFE) genotype and atherosclerosis: Increased susceptibility to iron-induced vascular damage in C282Y carriers?
    Marielle F Engberink
    Wageningen University, Division of Human Nutrition, Wageningen, The Netherlands
    Atherosclerosis 211:520-5. 2010
  7. ncbi Low concentrations of folate, not hyperhomocysteinemia, are associated with carotid intima-media thickness
    Jane Durga
    Division of Human Nutrition, Wageningen University, PO Box 8129, 6700 EV Wageningen, The Netherlands
    Atherosclerosis 179:285-92. 2005
  8. ncbi No effect of folic acid supplementation in the course of 1 year on haemostasis markers and C-reactive protein in older adults
    Mariska Klerk
    Wageningen Centre for Food Sciences, c o Wageningen University, Division of Human Nutrition, P O Box 8129, 6700 EV Wageningen, The Netherlands
    Thromb Haemost 94:96-100. 2005
  9. ncbi Effect of lowering of homocysteine levels on inflammatory markers: a randomized controlled trial
    Jane Durga
    Division of Human Nutrition, Wageningen University, and Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    Arch Intern Med 165:1388-94. 2005
  10. ncbi Validation of a food frequency questionnaire to assess folate intake of Dutch elderly people
    Ondine van de Rest
    Division of Human Nutrition, Wageningen University, The Netherlands
    Br J Nutr 98:1014-20. 2007

Collaborators

Detail Information

Publications15

  1. ncbi Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial
    Jane Durga
    Division of Human Nutrition, Wageningen University, 6700 EV Wageningen, Netherlands
    Lancet 369:208-16. 2007
    ....
  2. ncbi Effects of folic acid supplementation on hearing in older adults: a randomized, controlled trial
    Jane Durga
    Wageningen University and Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    Ann Intern Med 146:1-9. 2007
    ..Age-related hearing loss is a common chronic condition of elderly persons. Low folate status has been associated with poor hearing...
  3. ncbi Association of folate with hearing is dependent on the 5,10-methylenetetrahdyrofolate reductase 677C-->T mutation
    Jane Durga
    Division of Human Nutrition, Wageningen University, P O Box 8129, 6700 EV Wageningen, The Netherlands
    Neurobiol Aging 27:482-9. 2006
    ..10, p = 0.291). This supports the hypothesis that a greater one-carbon moiety commitment to de novo synthesis of nucleotides and an increase in formyl-folate derivatives relative to methyl-folate derivatives is protective for hearing...
  4. doi Effect of 3 y of folic acid supplementation on the progression of carotid intima-media thickness and carotid arterial stiffness in older adults
    Jane Durga
    Division of Human Nutrition, Wageningen University, Wageningen, Netherlands
    Am J Clin Nutr 93:941-9. 2011
    ..Randomized controlled trials in vascular patients have failed to show that folic acid reduces the risk of recurrent vascular disease, whereas such trials are lacking in the general population...
  5. ncbi Folate and the methylenetetrahydrofolate reductase 677C-->T mutation correlate with cognitive performance
    Jane Durga
    Division of Human Nutrition, Wageningen University, 6700 EV Wageningen, The Netherlands
    Neurobiol Aging 27:334-43. 2006
    ..15, 95% CI: -0.30 to 0.00). Low concentrations of erythrocyte folate are associated with decreased cognitive performance, possibly through a homocysteine-independent mechanism such as DNA infidelity and mitochondrial decay...
  6. doi Hemochromatosis (HFE) genotype and atherosclerosis: Increased susceptibility to iron-induced vascular damage in C282Y carriers?
    Marielle F Engberink
    Wageningen University, Division of Human Nutrition, Wageningen, The Netherlands
    Atherosclerosis 211:520-5. 2010
    ..It has also been postulated that the C282Y mutation could alter aspects of iron metabolism. We examined the relationship between the C282Y mutation, iron status, and carotid intima-media thickness (IMT) as a marker of atherosclerosis...
  7. ncbi Low concentrations of folate, not hyperhomocysteinemia, are associated with carotid intima-media thickness
    Jane Durga
    Division of Human Nutrition, Wageningen University, PO Box 8129, 6700 EV Wageningen, The Netherlands
    Atherosclerosis 179:285-92. 2005
    ....
  8. ncbi No effect of folic acid supplementation in the course of 1 year on haemostasis markers and C-reactive protein in older adults
    Mariska Klerk
    Wageningen Centre for Food Sciences, c o Wageningen University, Division of Human Nutrition, P O Box 8129, 6700 EV Wageningen, The Netherlands
    Thromb Haemost 94:96-100. 2005
    ..Although homocysteine is associated with vascular disease risk in the general population, marked lowering of slightly elevated homocysteine concentrations by one-year folic acid supplementation does not influence haemostasis markers...
  9. ncbi Effect of lowering of homocysteine levels on inflammatory markers: a randomized controlled trial
    Jane Durga
    Division of Human Nutrition, Wageningen University, and Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    Arch Intern Med 165:1388-94. 2005
    ..We investigated the effect of lowering homocysteine concentrations by means of folic acid supplementation on markers of inflammation...
  10. ncbi Validation of a food frequency questionnaire to assess folate intake of Dutch elderly people
    Ondine van de Rest
    Division of Human Nutrition, Wageningen University, The Netherlands
    Br J Nutr 98:1014-20. 2007
    ..Our FFQ showed a weak correlation between folate intake and blood folate concentrations and reproducibility was acceptable. This FFQ is able to rank subjects according to their folate intake...
  11. ncbi n 3 fatty acid proportions in plasma and cognitive performance in older adults
    Carla Dullemeijer
    Wageningen Centre for Food Sciences, Wageningen, Netherlands
    Am J Clin Nutr 86:1479-85. 2007
    ..However, limited data exist on the association between n-3 PUFAs and performance in specific cognitive domains...
  12. ncbi Blood donation, body iron status and carotid intima-media thickness
    Marielle F Engberink
    Wageningen University, Division of Human Nutrition, Wageningen, The Netherlands
    Atherosclerosis 196:856-62. 2008
    ..CIMT was not significantly related to NTBI. Frequent blood donation, resulting in lowered body iron, might give some protection against accelerated atherosclerosis...
  13. ncbi Homocysteine and carotid intima-media thickness: a critical appraisal of the evidence
    Jane Durga
    Division of Human Nutrition, Wageningen Centre for Food Sciences, Wageningen University, PO Box 8129, 6700 EV Wageningen, The Netherlands
    Atherosclerosis 176:1-19. 2004
    ..The relationship between two important determinants of hyperhomocysteinemia in the general population-folate status and the 677C --> T methylenetetrahydrofolate reductase (MTHFR) polymorphism-and CIMT is also covered...
  14. ncbi Erythrocyte folate and plasma DHA in the FACIT study
    Carla Dullemeijer
    Lancet 370:216. 2007
  15. ncbi Gender and body size affect the response of erythrocyte folate to folic acid treatment
    Renate M Winkels
    Top Institute Food and Nutrition, 6709PA Wageningen, The Netherlands
    J Nutr 138:1456-61. 2008
    ..This could be an indication that the RDA for folate should be higher for men than for women, or that the RDA should be expressed per kilogram of lean body mass...