Research Topics
Species | Jane DurgaSummaryCountry: Switzerland Publications
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Detail Information
Publications
Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trialJane Durga
Division of Human Nutrition, Wageningen University, 6700 EV Wageningen, Netherlands
Lancet 369:208-16. 2007....- Effects of folic acid supplementation on hearing in older adults: a randomized, controlled trialJane Durga
Wageningen University and Wageningen Centre for Food Sciences, Wageningen, The Netherlands
Ann Intern Med 146:1-9. 2007..Age-related hearing loss is a common chronic condition of elderly persons. Low folate status has been associated with poor hearing... - Association of folate with hearing is dependent on the 5,10-methylenetetrahdyrofolate reductase 677C-->T mutationJane Durga
Division of Human Nutrition, Wageningen University, P O Box 8129, 6700 EV Wageningen, The Netherlands
Neurobiol Aging 27:482-9. 2006..10, p = 0.291). This supports the hypothesis that a greater one-carbon moiety commitment to de novo synthesis of nucleotides and an increase in formyl-folate derivatives relative to methyl-folate derivatives is protective for hearing... 
Effect of 3 y of folic acid supplementation on the progression of carotid intima-media thickness and carotid arterial stiffness in older adultsJane Durga
Division of Human Nutrition, Wageningen University, Wageningen, Netherlands
Am J Clin Nutr 93:941-9. 2011..Randomized controlled trials in vascular patients have failed to show that folic acid reduces the risk of recurrent vascular disease, whereas such trials are lacking in the general population...- Folate and the methylenetetrahydrofolate reductase 677C-->T mutation correlate with cognitive performanceJane Durga
Division of Human Nutrition, Wageningen University, 6700 EV Wageningen, The Netherlands
Neurobiol Aging 27:334-43. 2006..15, 95% CI: -0.30 to 0.00). Low concentrations of erythrocyte folate are associated with decreased cognitive performance, possibly through a homocysteine-independent mechanism such as DNA infidelity and mitochondrial decay... - Hemochromatosis (HFE) genotype and atherosclerosis: Increased susceptibility to iron-induced vascular damage in C282Y carriers?Marielle F Engberink
Wageningen University, Division of Human Nutrition, Wageningen, The Netherlands
Atherosclerosis 211:520-5. 2010..It has also been postulated that the C282Y mutation could alter aspects of iron metabolism. We examined the relationship between the C282Y mutation, iron status, and carotid intima-media thickness (IMT) as a marker of atherosclerosis... - Low concentrations of folate, not hyperhomocysteinemia, are associated with carotid intima-media thicknessJane Durga
Division of Human Nutrition, Wageningen University, PO Box 8129, 6700 EV Wageningen, The Netherlands
Atherosclerosis 179:285-92. 2005.... - No effect of folic acid supplementation in the course of 1 year on haemostasis markers and C-reactive protein in older adultsMariska Klerk
Wageningen Centre for Food Sciences, c/o Wageningen University, Division of Human Nutrition, P.O. Box 8129, 6700 EV Wageningen, The Netherlands
Thromb Haemost 94:96-100. 2005..Although homocysteine is associated with vascular disease risk in the general population, marked lowering of slightly elevated homocysteine concentrations by one-year folic acid supplementation does not influence haemostasis markers... - Effect of lowering of homocysteine levels on inflammatory markers: a randomized controlled trialJane Durga
Division of Human Nutrition, Wageningen University, and Wageningen Centre for Food Sciences, Wageningen, The Netherlands
Arch Intern Med 165:1388-94. 2005..We investigated the effect of lowering homocysteine concentrations by means of folic acid supplementation on markers of inflammation... - Validation of a food frequency questionnaire to assess folate intake of Dutch elderly peopleOndine van de Rest
Division of Human Nutrition, Wageningen University, The Netherlands
Br J Nutr 98:1014-20. 2007..Our FFQ showed a weak correlation between folate intake and blood folate concentrations and reproducibility was acceptable. This FFQ is able to rank subjects according to their folate intake... - n 3 fatty acid proportions in plasma and cognitive performance in older adultsCarla Dullemeijer
Wageningen Centre for Food Sciences, Wageningen, Netherlands
Am J Clin Nutr 86:1479-85. 2007..However, limited data exist on the association between n-3 PUFAs and performance in specific cognitive domains... - Blood donation, body iron status and carotid intima-media thicknessMarielle F Engberink
Wageningen University, Division of Human Nutrition, Wageningen, The Netherlands
Atherosclerosis 196:856-62. 2008..CIMT was not significantly related to NTBI. Frequent blood donation, resulting in lowered body iron, might give some protection against accelerated atherosclerosis... - Homocysteine and carotid intima-media thickness: a critical appraisal of the evidenceJane Durga
Division of Human Nutrition, Wageningen Centre for Food Sciences, Wageningen University, PO Box 8129, 6700 EV Wageningen, The Netherlands
Atherosclerosis 176:1-19. 2004..The relationship between two important determinants of hyperhomocysteinemia in the general population-folate status and the 677C --> T methylenetetrahydrofolate reductase (MTHFR) polymorphism-and CIMT is also covered... - Erythrocyte folate and plasma DHA in the FACIT studyCarla Dullemeijer
Lancet 370:216. 2007 - Gender and body size affect the response of erythrocyte folate to folic acid treatmentRenate M Winkels
Top Institute Food and Nutrition, 6709PA Wageningen, The Netherlands
J Nutr 138:1456-61. 2008..This could be an indication that the RDA for folate should be higher for men than for women, or that the RDA should be expressed per kilogram of lean body mass...