Research Topics
| G ZanettiSummaryAffiliation: Centre Hospitalier Universitaire Vaudois Country: Switzerland Publications
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Detail Information
Publications
[Infectious diseases in the ambulatory care setting]G Zanetti
Service des Maladies Infectieuses, et Division autonome de médecine, preventive hospitalière, CHUV, 1011 Lausanne
Rev Med Suisse 1:134, 136-9. 2005....
Meropenem (1.5 g/day) is as effective as imipenem/cilastatin (2 g/day) for the treatment of moderately severe intra-abdominal infectionsG Zanetti
Division of Infectious Diseases, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
Int J Antimicrob Agents 11:107-13. 1999..1 vs 86.1%, respectively), were not statistically significant. Both drugs were generally well tolerated. Thus, meropenem 0.5 g/8 h is as clinically effective and well tolerated as imipenem/cilastatin 0.5 g/6 h in moderately severe IAIs...
Clinical consequences and cost of limiting use of vancomycin for perioperative prophylaxis: example of coronary artery bypass surgeryG Zanetti
Channing Laboratory, Brigham and Women s Hospital, and Eastern Massachusetts CDC Prevention Epicenter, Boston, USA
Emerg Infect Dis 7:820-7. 2001..Data on vancomycin's impact on resistance are needed to quantify the trade-off between individual patients' improved clinical outcomes and lower costs and the future long-term consequences to society...
Intraoperative redosing of cefazolin and risk for surgical site infection in cardiac surgeryG Zanetti
Brigham and Women s Hospital, Harvard Medical School, and Eastern Massachusetts CDC Prevention Epicenter, Boston, USA
Emerg Infect Dis 7:828-31. 2001..44, 95% CI 0.23-0.86). Intraoperative redosing of cefazolin was associated with a 16% reduction in the overall risk for surgical site infection after cardiac surgery, including procedures lasting <240 min...
Cefepime versus imipenem-cilastatin for treatment of nosocomial pneumonia in intensive care unit patients: a multicenter, evaluator-blind, prospective, randomized studyG Zanetti
Division of Infectious Diseases, Department of Microbiology, and Intensive Care Unit, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
Antimicrob Agents Chemother 47:3442-7. 2003..aeruginosa. Selection of a single agent for therapy of nosocomial pneumonia should be guided by local resistance patterns...
Investigation of classical epidemiological links between patients harbouring identical, non-predominant meticillin-resistant Staphylococcus aureus genotypes and lessons for epidemiological trackingL Senn
Hospital Preventive Medicine Service, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
J Hosp Infect 79:202-5. 2011..A prospective surveillance of MRSA genotypes could help to target epidemiological tracking in order to recognise new risk factors in hospital and community settings, or emergence of new epidemic clones...
Changes in the use of broad-spectrum antibiotics after cefepime shortage: a time series analysisC Plüss-Suard
Service of Hospital Preventive Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
Antimicrob Agents Chemother 56:989-94. 2012..aeruginosa in hospitals. This warrants caution with regard to shortages and withdrawals of antibiotics...
Usefulness of double locus sequence typing (DLST) for regional and international epidemiological surveillance of methicilin-resistant Staphylococcus aureusP Basset
Service of Hospital Preventive Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Clin Microbiol Infect 16:1289-96. 2010..It is only the combination of data from different methods that gives the best chance of describing precisely the epidemiology and phylogeny of MRSA...
Comparison of hospital-wide and unit-specific cumulative antibiograms in hospital- and community-acquired infectionF Lamoth
Infectious Diseases Service, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Rue du Bugnon 46, 1011 Lausanne, Switzerland
Infection 38:249-53. 2010..We investigated additional information inferred by aggregating cumulative antibiograms by type of unit or according to the place of acquisition (i.e. community vs. hospital) of the bacteria...
Which anatomical sites should be sampled for screening of methicillin-resistant Staphylococcus aureus carriage by culture or by rapid PCR test?L Senn
Service of Hospital Preventive Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Clin Microbiol Infect 18:E31-3. 2012..In conclusion, neither by culture nor by rapid PCR test is nose sampling alone sufficient for MRSA detection. Additional anatomical sites should include at least the groin and throat...
Molecular epidemiology of Pseudomonas aeruginosa in intensive care units over a 10-year period (1998-2007)M Cuttelod
Hospital Preventive Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Clin Microbiol Infect 17:57-62. 2011..The present study shows that repeated molecular typing can help identify variations in the epidemiology of P. aeruginosa in ICU patients and guide infection control measures...
Impact of standardised review of intravenous antibiotic therapy 72 hours after prescription in two internal medicine wardsO Manuel
Service of Hospital Preventive Medicine and Service of Infectious Diseases, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
J Hosp Infect 74:326-31. 2010..0 days, P=0.007). Patients included in the intervention group had lower antibiotic consumption than patients in the control group, but the intervention had no significant impact on the overall antibiotic consumption of the two wards...
[Bioterrorism: ideas of first resource medicine]P Staeger
Rev Med Suisse 3:2495-8, 2500-1. 2007
Changing molecular epidemiology of methicillin-resistant Staphylococcus aureus in a small geographic area over an eight-year periodD S Blanc
Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
J Clin Microbiol 45:3729-36. 2007..Moreover, MRSA clones were replaced by other emerging clones, suggesting a rapid change...
Hospital antibiotic consumption in Switzerland: comparison of a multicultural country with EuropeC Plüss-Suard
Department of Pharmacy, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
J Hosp Infect 79:166-71. 2011..Some of the patterns of variation in consumption levels noticed among European countries are also observed among the cultural regions of Switzerland...
[Antimicrobial agents and renal elimination: towards individual dosage adjustment?]C Willi-Robatel
Division de pharmacologie et toxicologie cliniques, Département des laboratoires, CHUV, Lausanne
Rev Med Suisse 8:894-900. 2012..The literature has been reviewed and compared to a predictive model of the fraction of drug cleared by the kidney based on the Dettli's principle. Revised drug dosing recommendations integrating these predictive parameters are proposed...
Randomized controlled trial of peripherally inserted central catheters vs. peripheral catheters for middle duration in-hospital intravenous therapyD Periard
Department of Angiology, Lausanne University Hospital, CHUV, Lausanne, Switzerland
J Thromb Haemost 6:1281-8. 2008..The safety, efficacy, comfort, and cost-effectiveness of peripherally inserted central catheters (PICCs) were compared to peripheral catheters (PCs) in a randomized controlled trial...
Blood samples drawn for culture as a surrogate marker for case-mix adjustment of hospital antibiotic useF Lamoth
Service of Infectious Deseases, Department of Medicine, University Hospital, Lausanne, Switzerland
Clin Microbiol Infect 13:454-6. 2007..Blood culture numbers enabled easy and accurate identification of periods with a drift in antibiotic consumption ina medical ward...
Legionella pneumophila aortitis in a heart transplant recipientS Guyot
Service of Infectious Diseases, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
Transpl Infect Dis 9:58-9. 2007..A Teflon ring implanted around the aortic suture line during the intervention may have contributed to the unusual localization of the infection. The patient was successfully treated with antibiotics and aortic reconstruction...
Contribution of TNF/TNF receptor and of Fas ligand to toxicity in murine models of endotoxemia and bacterial peritonitisD Heumann
Department of Internal Medicine, CHUV, Laussane, Switzerland
J Inflamm 47:173-9. 1995..Thus, these observations confirmed the pathogenic role of TNF/TNFR in endotoxemia and its beneficial role in local bacterial infections. In addition the data ruled out a major role for Fas/FasL in septic shock in mice...
[Infectious diseases (beside AIDS)]C Bellini
Service de Médecine Préventive Hospitalière, CHUV, 1011 Lausanne
Rev Med Suisse 4:34, 36-9. 2008..Finally, we address a basic research topic that may change practice in the future: the relationship between individual susceptibility to infection and innate immunity...
[Infectious diseases (beside AIDS)]G Zanetti
Service de médecine preventive, hospitalière et Service des maladies infectieuses, CHUV, Lausanne
Rev Med Suisse 3:26-9. 2007..A new Papillomavirus vaccine is now available for prevention of cervical cancer...
Latent tuberculosis infection among undergraduate medical students in Rio de Janeiro State, BrazilE G Teixeira
Department of Internal Medicine, Gama Filho University, Rio de Janeiro, Brazil
Int J Tuberc Lung Dis 9:841-7. 2005..Five medical schools in three cities with different tuberculosis (TB) incidence rates in Rio de Janeiro State, Brazil...
