Marc R Suter

Summary

Affiliation: Centre Hospitalier Universitaire Vaudois
Country: Switzerland

Publications

  1. pmc Large A-fiber activity is required for microglial proliferation and p38 MAPK activation in the spinal cord: different effects of resiniferatoxin and bupivacaine on spinal microglial changes after spared nerve injury
    Marc R Suter
    Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Mol Pain 5:53. 2009
  2. pmc Glial cells and chronic pain
    Romain Daniel Gosselin
    Pain Research Unit, Department of Anesthesiology, University Hospital Center, University of Lausanne, Lausanne, Switzerland
    Neuroscientist 16:519-31. 2010
  3. pmc Perioperative nerve blockade: clues from the bench
    M R Suter
    Pain Center, Department of Anesthesiology, University Hospital Center and University of Lausanne, 1011 Lausanne, Switzerland
    Anesthesiol Res Pract 2011:124898. 2011
  4. ncbi request reprint [New concepts in the pathophysiology, diagnosis and treatment of neuropathic pain]
    Marc R Suter
    Centre d antalogie, Service d anesthésiologie, CHUV, Lausanne
    Rev Med Suisse 9:1346, 1348-50. 2013
  5. doi request reprint Rufinamide attenuates mechanical allodynia in a model of neuropathic pain in the mouse and stabilizes voltage-gated sodium channel inactivated state
    Marc R Suter
    Pain Center, Department of Anesthesiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland
    Anesthesiology 118:160-72. 2013
  6. ncbi request reprint Nerve conduction blockade in the sciatic nerve prevents but does not reverse the activation of p38 mitogen-activated protein kinase in spinal microglia in the rat spared nerve injury model
    Yeong Ray Wen
    Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Anesthesiology 107:312-21. 2007
  7. pmc p38 MAPK, microglial signaling, and neuropathic pain
    Ru Rong Ji
    Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Mol Pain 3:33. 2007
  8. pmc JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain
    Yong Jing Gao
    Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Neurosci 29:4096-108. 2009
  9. ncbi request reprint [Glial cells and chronic pain: from the laboratory to clinical hope]
    Christine B Clarke
    Centre d antalgie, Service d anesthésiologie, CHUV, 1011 Lausanne
    Rev Med Suisse 9:1342-5. 2013
  10. ncbi request reprint Voltage-gated sodium channel expression in mouse DRG after SNI leads to re-evaluation of projections of injured fibers
    Cedric J Laedermann
    Pain Center, Department of Anesthesiology, University Hospital Center and University of Lausanne, Lausanne 1011, Switzerland
    Mol Pain 10:19. 2014

Detail Information

Publications12

  1. pmc Large A-fiber activity is required for microglial proliferation and p38 MAPK activation in the spinal cord: different effects of resiniferatoxin and bupivacaine on spinal microglial changes after spared nerve injury
    Marc R Suter
    Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Mol Pain 5:53. 2009
    ....
  2. pmc Glial cells and chronic pain
    Romain Daniel Gosselin
    Pain Research Unit, Department of Anesthesiology, University Hospital Center, University of Lausanne, Lausanne, Switzerland
    Neuroscientist 16:519-31. 2010
    ..The authors review the conceptual advances made in the recent years about the implication of central and peripheral glia in animal models of chronic pain and discuss the possibility to translate it into human therapies in the future...
  3. pmc Perioperative nerve blockade: clues from the bench
    M R Suter
    Pain Center, Department of Anesthesiology, University Hospital Center and University of Lausanne, 1011 Lausanne, Switzerland
    Anesthesiol Res Pract 2011:124898. 2011
    ..Finally, we will discuss three major disadvantages of the current blockade: the absence of blockade of myelinated fibers, the inappropriate duration of blockade, and the existence of activity-independent mechanisms...
  4. ncbi request reprint [New concepts in the pathophysiology, diagnosis and treatment of neuropathic pain]
    Marc R Suter
    Centre d antalogie, Service d anesthésiologie, CHUV, Lausanne
    Rev Med Suisse 9:1346, 1348-50. 2013
    ..The last articles remind us that interventional therapies, not always very invasive, have a future potential in the therapy of frequent conditions such as head pain disorders...
  5. doi request reprint Rufinamide attenuates mechanical allodynia in a model of neuropathic pain in the mouse and stabilizes voltage-gated sodium channel inactivated state
    Marc R Suter
    Pain Center, Department of Anesthesiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland
    Anesthesiology 118:160-72. 2013
    ..Sodium channel blockers currently used to treat neuropathic pain are poorly tolerated. Getting new molecules to clinical use is laborious. We here propose a drug already marketed as anticonvulsant, rufinamide...
  6. ncbi request reprint Nerve conduction blockade in the sciatic nerve prevents but does not reverse the activation of p38 mitogen-activated protein kinase in spinal microglia in the rat spared nerve injury model
    Yeong Ray Wen
    Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Anesthesiology 107:312-21. 2007
    ..Nerve injury-induced ectopic spontaneous activity is essential for the generation of neuropathic pain. The authors examined whether peripheral neural activity is necessary for p38 activation in spinal microglia...
  7. pmc p38 MAPK, microglial signaling, and neuropathic pain
    Ru Rong Ji
    Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Mol Pain 3:33. 2007
    ..Taken together, current data suggest that p38 plays a critical role in microglial signaling under neuropathic pain conditions and represents a valuable therapeutic target for neuropathic pain management...
  8. pmc JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain
    Yong Jing Gao
    Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Neurosci 29:4096-108. 2009
    ..Inhibition of the JNK/MCP-1 pathway may provide a new therapy for neuropathic pain management...
  9. ncbi request reprint [Glial cells and chronic pain: from the laboratory to clinical hope]
    Christine B Clarke
    Centre d antalgie, Service d anesthésiologie, CHUV, 1011 Lausanne
    Rev Med Suisse 9:1342-5. 2013
    ..This therapeutic hope is particularly highlighted in our discussion of the first completed clinical trials employing glial inhibitors in the treatment of chronic pain...
  10. ncbi request reprint Voltage-gated sodium channel expression in mouse DRG after SNI leads to re-evaluation of projections of injured fibers
    Cedric J Laedermann
    Pain Center, Department of Anesthesiology, University Hospital Center and University of Lausanne, Lausanne 1011, Switzerland
    Mol Pain 10:19. 2014
    ..In the SNI model, injured and non-injured neurons were intermingled in lumbar DRG, which were pooled to increase the tissue available for experiments...
  11. pmc Do glial cells control pain?
    Marc R Suter
    Pain Research Center, Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Neuron Glia Biol 3:255-68. 2007
    ..Investigating signaling mechanisms in microglia might lead to more effective management of devastating chronic pain...
  12. pmc Reverse transcription quantitative real-time polymerase chain reaction reference genes in the spared nerve injury model of neuropathic pain: validation and literature search
    Nicolas Piller
    Pain Center, Department of Anesthesiology, University Hospital Center and University of Lausanne, Avenue du Bugnon 46, 1011 Lausanne, Switzerland
    BMC Res Notes 6:266. 2013
    ..We compared the candidate genes and established a stability ranking using the geNorm algorithm. Finally, we assessed the number of reference genes necessary for accurate normalization in this neuropathic pain model...