Julius Popp

Summary

Affiliation: Centre Hospitalier Universitaire Vaudois
Country: Switzerland

Publications

  1. doi request reprint Cerebral and extracerebral cholesterol metabolism and CSF markers of Alzheimer's disease
    Julius Popp
    Department of Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland
    Biochem Pharmacol 86:37-42. 2013
  2. doi request reprint Prevention and treatment options for postoperative delirium in the elderly
    Julius Popp
    Department of Psychiatry, Division of Old Age Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland
    Curr Opin Psychiatry 25:515-21. 2012
  3. doi request reprint Cholesterol metabolism is associated with soluble amyloid precursor protein production in Alzheimer's disease
    Julius Popp
    Department of Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland
    J Neurochem 123:310-6. 2012
  4. doi request reprint CYP46A1 variants influence Alzheimer's disease risk and brain cholesterol metabolism
    Heike Kolsch
    Department of Psychiatry, University of Bonn, Germany
    Eur Psychiatry 24:183-90. 2009
  5. doi request reprint CETP polymorphisms influence cholesterol metabolism but not Alzheimer's disease risk
    Homeira Qureischie
    Department of Psychiatry, University of Bonn, Sigmund Freud Strabetae 25, 53105 Bonn, Germany
    Brain Res 1232:1-6. 2008
  6. ncbi request reprint Alterations of cholesterol precursor levels in Alzheimer's disease
    Heike Kolsch
    Department of Psychiatry, University of Bonn, 53105 Bonn, Germany
    Biochim Biophys Acta 1801:945-50. 2010
  7. doi request reprint Cerebrospinal fluid markers for Alzheimer's disease over the lifespan: effects of age and the APOEε4 genotype
    Julius Popp
    Department of Psychiatry, University of Bonn, Bonn, Germany
    J Alzheimers Dis 22:459-68. 2010
  8. doi request reprint Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease
    Julius Popp
    Department of Psychiatry, University of Bonn, 53105 Bonn, Germany
    J Alzheimers Dis 18:819-28. 2009
  9. doi request reprint Association of N-acetylaspartate and cerebrospinal fluid Aβ42 in dementia
    Frank Jessen
    Department of Psychiatry, University of Bonn, Bonn, Germany
    J Alzheimers Dis 27:393-9. 2011
  10. ncbi request reprint CSF cortisol in Alzheimer's disease and mild cognitive impairment
    Julius Popp
    Department of Psychiatry, University of Bonn, Bonn, Germany
    Neurobiol Aging 30:498-500. 2009

Collaborators

Detail Information

Publications17

  1. doi request reprint Cerebral and extracerebral cholesterol metabolism and CSF markers of Alzheimer's disease
    Julius Popp
    Department of Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland
    Biochem Pharmacol 86:37-42. 2013
    ..The results suggest that alterations of CNS cholesterol de novo genesis and metabolism are related to neurodegeneration and in particular to the cerebral accumulation of phosphorylated tau...
  2. doi request reprint Prevention and treatment options for postoperative delirium in the elderly
    Julius Popp
    Department of Psychiatry, Division of Old Age Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland
    Curr Opin Psychiatry 25:515-21. 2012
    ..To review recent findings and developments in strategies for prevention and treatment of postoperative delirium...
  3. doi request reprint Cholesterol metabolism is associated with soluble amyloid precursor protein production in Alzheimer's disease
    Julius Popp
    Department of Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland
    J Neurochem 123:310-6. 2012
    ..Furthermore, plasma 27-OHC concentrations were associated with the CSF sAPP levels. The results suggest that high CSF concentrations of cholesterol, 24S-OHC, and 27-OHC are associated with increased production of both sAPP forms in AD...
  4. doi request reprint CYP46A1 variants influence Alzheimer's disease risk and brain cholesterol metabolism
    Heike Kolsch
    Department of Psychiatry, University of Bonn, Germany
    Eur Psychiatry 24:183-90. 2009
    ..Only few gene variations in CYP46 gene (CYP46A1) have been investigated for their relevance as genetic risk factors of Alzheimer's disease (AD) and results are contradictory...
  5. doi request reprint CETP polymorphisms influence cholesterol metabolism but not Alzheimer's disease risk
    Homeira Qureischie
    Department of Psychiatry, University of Bonn, Sigmund Freud Strabetae 25, 53105 Bonn, Germany
    Brain Res 1232:1-6. 2008
    ..Our data suggest that CETP gene variations influence cerebral and peripheral cholesterol metabolism, but not AD risk...
  6. ncbi request reprint Alterations of cholesterol precursor levels in Alzheimer's disease
    Heike Kolsch
    Department of Psychiatry, University of Bonn, 53105 Bonn, Germany
    Biochim Biophys Acta 1801:945-50. 2010
    ..These findings raise doubt on a beneficial effect of cholesterol lowering treatment in manifest AD...
  7. doi request reprint Cerebrospinal fluid markers for Alzheimer's disease over the lifespan: effects of age and the APOEε4 genotype
    Julius Popp
    Department of Psychiatry, University of Bonn, Bonn, Germany
    J Alzheimers Dis 22:459-68. 2010
    ..They also suggest that the decrease of Aβ1-42, but not the increase of pTau181 CSF levels is accelerated by the APOEε4 genotype in middle-aged and older adults with normal cognition...
  8. doi request reprint Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease
    Julius Popp
    Department of Psychiatry, University of Bonn, 53105 Bonn, Germany
    J Alzheimers Dis 18:819-28. 2009
    ..The results suggest that alteration of the homocysteine metabolism is related to increased accumulation of phosphorylated tau and may contribute to the neurofibrillary pathology in normal aging and in AD...
  9. doi request reprint Association of N-acetylaspartate and cerebrospinal fluid Aβ42 in dementia
    Frank Jessen
    Department of Psychiatry, University of Bonn, Bonn, Germany
    J Alzheimers Dis 27:393-9. 2011
    ..Since the NAA concentration is coupled to neuronal mitochondrial function, the correlation between NAA and Aβ42 may reflect the interaction between disrupted mitochondrial pathways and amyloid production...
  10. ncbi request reprint CSF cortisol in Alzheimer's disease and mild cognitive impairment
    Julius Popp
    Department of Psychiatry, University of Bonn, Bonn, Germany
    Neurobiol Aging 30:498-500. 2009
    ..001) and to MCI subjects (p=0.002). There was no significant increase of cortisol in MCI subjects compared with controls suggesting that the increase of CSF cortisol is not an early event in the course of AD...
  11. ncbi request reprint Glucose metabolism, gray matter structure, and memory decline in subjective memory impairment
    Lukas Scheef
    Department of Radiology, University of Bonn, Bonn, Germany
    Neurology 79:1332-9. 2012
    ..To identify biological evidence for Alzheimer disease (AD) in individuals with subjective memory impairment (SMI) and unimpaired cognitive performance and to investigate the longitudinal cognitive course in these subjects...
  12. doi request reprint RXRA gene variations influence Alzheimer's disease risk and cholesterol metabolism
    Heike Kolsch
    Department of Psychiatry, University of Bonn, Bonn, Germany
    J Cell Mol Med 13:589-98. 2009
    ..009, plasma: P= 0.002; TGC haplotype: CSF: P= 0.019, plasma: P= 0.005). Our results suggest that RXRA gene variants might act as risk factor for AD via an influence on cerebral cholesterol metabolism...
  13. doi request reprint Volume loss of the medial temporal lobe structures in subjective memory impairment
    Nadine Striepens
    Department of Psychiatry, University of Bonn, Germany
    Dement Geriatr Cogn Disord 29:75-81. 2010
    ..In this study, we determined the volumes of the hippocampus, the entorhinal cortex (EC) and the amygdala to provide biological evidence for AD in SMI...
  14. doi request reprint Macrophage migration inhibitory factor in mild cognitive impairment and Alzheimer's disease
    Julius Popp
    University of Bonn, Department of Psychiatry, Bonn, Germany
    J Psychiatr Res 43:749-53. 2009
    ..407; p=0.023). These results demonstrate increased MIF production in AD and MCI suggesting that MIF may be involved in the occurring neuroinflammatory process at a clinical pre-dementia disease stage...
  15. doi request reprint Pharmacological treatment of dementia and mild cognitive impairment due to Alzheimer's disease
    Julius Popp
    Division of Old Age Psychiatry, Department of Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland
    Curr Opin Psychiatry 24:556-61. 2011
    ....
  16. ncbi request reprint Delirium and cognitive decline: more than a coincidence
    Julius Popp
    aDivision of Old Age Psychiatry, Department of Psychiatry bDepartment of Clinical Neuroscience, Leenaards Memory Center, University Hospital of Lausanne, Lausanne, Switzerland
    Curr Opin Neurol 26:634-9. 2013
    ..To review the recent findings on the relationships between delirium and cognitive decline in the elderly...
  17. doi request reprint Predisposing and precipitating factors of delirium after cardiac surgery: a prospective observational cohort study
    Ulf Guenther
    Klinik für Anästhesiologie and Operative Intensivmedizin, Universitätsklinikum der Rheinischen Friedrich Wilhelms Universität Bonn, Germany
    Ann Surg 257:1160-7. 2013
    ..To comprehensively assess pre-, intra-, and postoperative delirium risk factors as potential targets for intervention...