Jürg Nussberger

Summary

Affiliation: Centre Hospitalier Universitaire Vaudois
Country: Switzerland

Publications

  1. ncbi request reprint Measurement of immunoreactive angiotensin-(1-7) heptapeptide in human blood
    J Nussberger
    Hypertension Division CHUV, CH 1011 Lausanne, Switzerland
    Clin Chem 47:726-9. 2001
  2. ncbi request reprint Antagonizing the angiotensin II subtype 1 receptor: a focus on olmesartan medoxomil
    Jürg Nussberger
    Division of Hypertension and Vascular Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Clin Ther 26:A12-20. 2004
  3. ncbi request reprint Investigating mineralocorticoid hypertension
    Jürg Nussberger
    Division of Hypertension and Vascular Medicine, University Hospital Lausanne, Switzerland
    J Hypertens Suppl 21:S25-30. 2003
  4. ncbi request reprint Angiotensin II suppression in humans by the orally active renin inhibitor Aliskiren (SPP100): comparison with enalapril
    Juerg Nussberger
    Division of Hypertension and Vascular Medicine, University Hospital Lausanne, Switzerland
    Hypertension 39:E1-8. 2002
  5. ncbi request reprint Renal hemodynamic and natriuretic effects of concomitant Angiotensin-converting enzyme and neutral endopeptidase inhibition in men
    Frédéric Regamey
    Division of Hypertension and Vascular Medicine, CHUV, Lausanne, Switzerland
    Hypertension 40:266-72. 2002
  6. doi request reprint Swimming prevents vulnerable atherosclerotic plaque development in hypertensive 2-kidney, 1-clip mice by modulating angiotensin II type 1 receptor expression independently from hemodynamic changes
    Maxime Pellegrin
    Service of Vascular Medicine, Lausanne University Hospital, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Hypertension 53:782-9. 2009
  7. ncbi request reprint Blood pressure, cardiac, and renal responses to salt and deoxycorticosterone acetate in mice: role of Renin genes
    Qing Wang
    Division of Hypertension and Vascular Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    J Am Soc Nephrol 13:1509-16. 2002
  8. doi request reprint Renin inhibition by aliskiren prevents atherosclerosis progression: comparison with irbesartan, atenolol, and amlodipine
    Jürg Nussberger
    Service of Vascular Medicine, Department of Medicine, Lausanne University Hospital, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Hypertension 51:1306-11. 2008
  9. ncbi request reprint Metoprolol prevents sodium retention induced by lower body negative pressure in healthy men
    Gregoire Wuerzner
    Service de Nephrologie, Centre Hospitalier, Universitaire Vaudois, Lausanne, Switzerland
    Kidney Int 68:688-94. 2005
  10. doi request reprint Pharmacotherapy: Optimal blockade of the renin-angiotensin-aldosterone system
    Jürg Nussberger
    Division of Angiology and Hypertension, Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois CHUV, NES 6027, CH 1011 Lausanne, Switzerland
    Nat Rev Cardiol 10:183-4. 2013

Detail Information

Publications14

  1. ncbi request reprint Measurement of immunoreactive angiotensin-(1-7) heptapeptide in human blood
    J Nussberger
    Hypertension Division CHUV, CH 1011 Lausanne, Switzerland
    Clin Chem 47:726-9. 2001
    ..The Ang-(1-7) heptapeptide has been reported to have several physiological effects, including natriuresis, diuresis, vasodilation, and release of vasopressin and prostaglandins...
  2. ncbi request reprint Antagonizing the angiotensin II subtype 1 receptor: a focus on olmesartan medoxomil
    Jürg Nussberger
    Division of Hypertension and Vascular Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Clin Ther 26:A12-20. 2004
    ..Olmesartan medoxomil is the newest member of this class...
  3. ncbi request reprint Investigating mineralocorticoid hypertension
    Jürg Nussberger
    Division of Hypertension and Vascular Medicine, University Hospital Lausanne, Switzerland
    J Hypertens Suppl 21:S25-30. 2003
    ....
  4. ncbi request reprint Angiotensin II suppression in humans by the orally active renin inhibitor Aliskiren (SPP100): comparison with enalapril
    Juerg Nussberger
    Division of Hypertension and Vascular Medicine, University Hospital Lausanne, Switzerland
    Hypertension 39:E1-8. 2002
    ..Aliskiren has the potential to become the first orally active renin inhibitor that provides a true alternative to ACE-inhibitors and Ang II receptor antagonists in therapy for hypertension and other cardiovascular and renal diseases...
  5. ncbi request reprint Renal hemodynamic and natriuretic effects of concomitant Angiotensin-converting enzyme and neutral endopeptidase inhibition in men
    Frédéric Regamey
    Division of Hypertension and Vascular Medicine, CHUV, Lausanne, Switzerland
    Hypertension 40:266-72. 2002
    ..Omapatrilat combines potent ACE inhibition with a sustained natriuresis, which explains its well-documented potent antihypertensive efficacy...
  6. doi request reprint Swimming prevents vulnerable atherosclerotic plaque development in hypertensive 2-kidney, 1-clip mice by modulating angiotensin II type 1 receptor expression independently from hemodynamic changes
    Maxime Pellegrin
    Service of Vascular Medicine, Lausanne University Hospital, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Hypertension 53:782-9. 2009
    ..Ang II type 1 downregulation may protect the vessel wall from the Ang II proatherogenic effects. Moreover, data presented herein further emphasize the pivotal and blood pressure-independent role of Ang II in atherogenesis...
  7. ncbi request reprint Blood pressure, cardiac, and renal responses to salt and deoxycorticosterone acetate in mice: role of Renin genes
    Qing Wang
    Division of Hypertension and Vascular Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    J Am Soc Nephrol 13:1509-16. 2002
    ..Finally, these data provide further evidence that mineralocorticoids promote cardiac hypertrophy even in the absence of BP changes. This hypertrophic process is mediated in part by the activation of angiotensin II AT(1) receptors...
  8. doi request reprint Renin inhibition by aliskiren prevents atherosclerosis progression: comparison with irbesartan, atenolol, and amlodipine
    Jürg Nussberger
    Service of Vascular Medicine, Department of Medicine, Lausanne University Hospital, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Hypertension 51:1306-11. 2008
    ..The plasma renin concentration measurement by an indirect method did not confirm the excessive increase of plasma renin concentration reported in the literature during aliskiren compared with irbesartan or amlodipine treatment...
  9. ncbi request reprint Metoprolol prevents sodium retention induced by lower body negative pressure in healthy men
    Gregoire Wuerzner
    Service de Nephrologie, Centre Hospitalier, Universitaire Vaudois, Lausanne, Switzerland
    Kidney Int 68:688-94. 2005
    ..As beta-blockers play an important role in the management of CHF patients, the effects of metoprolol on the renal response were examined in healthy subjects during sustained LBNP...
  10. doi request reprint Pharmacotherapy: Optimal blockade of the renin-angiotensin-aldosterone system
    Jürg Nussberger
    Division of Angiology and Hypertension, Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois CHUV, NES 6027, CH 1011 Lausanne, Switzerland
    Nat Rev Cardiol 10:183-4. 2013
    ..Overdosing of RAAS inhibitors is occasionally observed when several agents are used together, and can cause adverse events such as hypotension, hyperkalaemia, and renal failure. We advocate optimal, rather than complete, RAAS blockade...
  11. ncbi request reprint Comparative angiotensin II receptor blockade in healthy volunteers: the importance of dosing
    Marc P Maillard
    Division of Hypertension and Vascular Medicine, University Hospital of Lausanne, Switzerland
    Clin Pharmacol Ther 71:68-76. 2002
    ..In this study we investigated the importance of drug dosing in mediating these differences by comparing the AT(1)-receptor blockade induced by 3 doses of valsartan with that obtained with 3 other antagonists at given doses...
  12. ncbi request reprint Effects of the peroxisomal proliferator-activated receptor-gamma agonist pioglitazone on renal and hormonal responses to salt in healthy men
    Anne Zanchi
    Division of Hypertension and Vascular Medicine, Department of Medicine, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland
    J Clin Endocrinol Metab 89:1140-5. 2004
    ..Pioglitazone stimulates plasma renin activity and favors sodium retention and weight gain in healthy volunteers. These effects could contribute to the development of edema in some subjects treated with glitazones...
  13. doi request reprint Blood pressure and renin-angiotensin system resetting in transgenic rats with elevated plasma Val5-angiotensinogen
    Jürgen Bohlender
    Division of Angiology and Hypertension, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    J Hypertens 30:1597-605. 2012
    ..The relationship between Ang-N, the resetting of the renin-angiotensin system, and BP still remains unclear. Angiotensin (Ang) II-induced genetic hypertension should respond to lisinopril treatment...
  14. ncbi request reprint Endogenous angiotensin II induces atherosclerotic plaque vulnerability and elicits a Th1 response in ApoE-/- mice
    Lucia Mazzolai
    Service of Angiology, CHUV, University of Lausanne, 1011 Lausanne, Rue du Bugnon 46, Switzerland
    Hypertension 44:277-82. 2004
    ....