Ph Conus

Summary

Affiliation: Centre Hospitalier Universitaire Vaudois
Country: Switzerland

Publications

  1. ncbi request reprint [Psychiatry]
    Patrice Guex
    Departement de Psychiatrie, CHUV, Lausanne
    Rev Med Suisse 7:150-3. 2011
  2. pmc Gender differences in first episode psychotic mania
    Sue M Cotton
    Orygen Youth Health Research Centre, University of Melbourne, Locked Bag 10 35 Poplar Road, Parkville, Victoria, 3052, Australia
    BMC Psychiatry 13:82. 2013
  3. pmc Is diagnosis enough to guide interventions in mental health? Using case formulation in clinical practice
    Craig A Macneil
    Early Psychosis Prevention and Intervention Centre EPPIC, and Orygen Youth Health Research Centre, ORYGEN Youth Health, 35 Poplar Road, Parkville, Melbourne, Victoria, 3052, Australia
    BMC Med 10:111. 2012
  4. ncbi request reprint [Psychiatry]
    P Conus
    Service de Psychiatrie Générale, Departement de Psychiatrie, CHUV, Site de Cery, Prilly
    Rev Med Suisse 9:76-9. 2013
  5. doi request reprint [First episode of mood disorders: an opportunity for early intervention in bipolar disorders]
    Ph Conus
    Département Psychiatrie CHUV, Universite de Lausanne, Clinique de Cery, Prilly, Suisse
    Encephale 36:S71-6. 2010
  6. doi request reprint Pretreatment and outcome correlates of past sexual and physical trauma in 118 bipolar I disorder patients with a first episode of psychotic mania
    Philippe Conus
    Treatment and Early Intervention in Psychosis Program, Département de Psychiatrie CHUV, Universite de Lausanne, Clinique de Cery, Prilly, Switzerland
    Bipolar Disord 12:244-52. 2010
  7. doi request reprint Pre-morbid and outcome correlates of first episode mania with psychosis: is a distinction between schizoaffective and bipolar I disorder valid in the early phase of psychotic disorders?
    Philippe Conus
    Treatment and Early Intervention in Psychosis Program TIPP, Département de Psychiatrie CHUV, Universite de Lausanne, Clinique de Cery, 1008 Prilly, Switzerland
    J Affect Disord 126:88-95. 2010
  8. doi request reprint The proximal prodrome to first episode mania--a new target for early intervention
    Philippe Conus
    Treatment and Early Intervention in Psychosis Program TIPP, Département Universitaire de Psychiatrie CHUV, Lausanne University, Clinique de Cery, Prilly, Switzerland
    Bipolar Disord 10:555-65. 2008
  9. pmc Pretreatment and outcome correlates of sexual and physical trauma in an epidemiological cohort of first-episode psychosis patients
    Philippe Conus
    Department of Psychiatry, Orygen Youth Health Research Centre, Centre for Youth Mental Health, University of Melbourne, Parkville, Victoria, Australia
    Schizophr Bull 36:1105-14. 2010
  10. doi request reprint Characterisation of the prodrome to a first episode of psychotic mania: results of a retrospective study
    Philippe Conus
    Traitement et Intervention Précoce dans les troubles Psychotiques TIPP Program, Département de Psychiatrie CHUV, Universite de Lausanne, Clinique de Cery, 1008 Prilly, Switzerland
    J Affect Disord 124:341-5. 2010

Detail Information

Publications36

  1. ncbi request reprint [Psychiatry]
    Patrice Guex
    Departement de Psychiatrie, CHUV, Lausanne
    Rev Med Suisse 7:150-3. 2011
    ..Systematic follow-up of the metabolic syndrome, often induced by atypical antipsychotics, belongs to those basic adjustment processes...
  2. pmc Gender differences in first episode psychotic mania
    Sue M Cotton
    Orygen Youth Health Research Centre, University of Melbourne, Locked Bag 10 35 Poplar Road, Parkville, Victoria, 3052, Australia
    BMC Psychiatry 13:82. 2013
    ..The aim of this paper was to delineate the impact of gender on premorbid history, onset, and 18 month outcomes of first episode psychotic mania (FEPM) patients...
  3. pmc Is diagnosis enough to guide interventions in mental health? Using case formulation in clinical practice
    Craig A Macneil
    Early Psychosis Prevention and Intervention Centre EPPIC, and Orygen Youth Health Research Centre, ORYGEN Youth Health, 35 Poplar Road, Parkville, Melbourne, Victoria, 3052, Australia
    BMC Med 10:111. 2012
    ....
  4. ncbi request reprint [Psychiatry]
    P Conus
    Service de Psychiatrie Générale, Departement de Psychiatrie, CHUV, Site de Cery, Prilly
    Rev Med Suisse 9:76-9. 2013
    ....
  5. doi request reprint [First episode of mood disorders: an opportunity for early intervention in bipolar disorders]
    Ph Conus
    Département Psychiatrie CHUV, Universite de Lausanne, Clinique de Cery, Prilly, Suisse
    Encephale 36:S71-6. 2010
    ....
  6. doi request reprint Pretreatment and outcome correlates of past sexual and physical trauma in 118 bipolar I disorder patients with a first episode of psychotic mania
    Philippe Conus
    Treatment and Early Intervention in Psychosis Program, Département de Psychiatrie CHUV, Universite de Lausanne, Clinique de Cery, Prilly, Switzerland
    Bipolar Disord 12:244-52. 2010
    ..To assess the prevalence and correlates of childhood and adolescent sexual and/or physical abuse (SPA) in bipolar I disorder (BDI) patients treated for a first episode of psychotic mania...
  7. doi request reprint Pre-morbid and outcome correlates of first episode mania with psychosis: is a distinction between schizoaffective and bipolar I disorder valid in the early phase of psychotic disorders?
    Philippe Conus
    Treatment and Early Intervention in Psychosis Program TIPP, Département de Psychiatrie CHUV, Universite de Lausanne, Clinique de Cery, 1008 Prilly, Switzerland
    J Affect Disord 126:88-95. 2010
    ..However, most studies have been conducted in chronic samples and have therefore been biased towards patients with poorer outcome, which may have hampered the possibility to identify significant differences between both diagnoses...
  8. doi request reprint The proximal prodrome to first episode mania--a new target for early intervention
    Philippe Conus
    Treatment and Early Intervention in Psychosis Program TIPP, Département Universitaire de Psychiatrie CHUV, Lausanne University, Clinique de Cery, Prilly, Switzerland
    Bipolar Disord 10:555-65. 2008
    ..This paper aims to gather current knowledge on the early phase of bipolar disorders in order to define new targets for early intervention...
  9. pmc Pretreatment and outcome correlates of sexual and physical trauma in an epidemiological cohort of first-episode psychosis patients
    Philippe Conus
    Department of Psychiatry, Orygen Youth Health Research Centre, Centre for Youth Mental Health, University of Melbourne, Parkville, Victoria, Australia
    Schizophr Bull 36:1105-14. 2010
    ..We assessed rate of stressful events, as well as premorbid and outcome correlates of past sexual and/or physical abuse (SPA) in an epidemiological FEP patients cohort...
  10. doi request reprint Characterisation of the prodrome to a first episode of psychotic mania: results of a retrospective study
    Philippe Conus
    Traitement et Intervention Précoce dans les troubles Psychotiques TIPP Program, Département de Psychiatrie CHUV, Universite de Lausanne, Clinique de Cery, 1008 Prilly, Switzerland
    J Affect Disord 124:341-5. 2010
    ....
  11. ncbi request reprint Symptomatic and functional outcome 12 months after a first episode of psychotic mania: barriers to recovery in a catchment area sample
    Philippe Conus
    Département Universitaire de Psychiatrie CHUV, Universite de Lausanne, Prilly, Switzerland
    Bipolar Disord 8:221-31. 2006
    ..Such studies have been conducted in selected samples with restrictive measures of outcome. We aimed to explore outcome and its predictors in a catchment area sample of first-episode psychotic mania of DSM-III-R bipolar I disorder...
  12. doi request reprint Rate and predictors of service disengagement in an epidemiological first-episode psychosis cohort
    Philippe Conus
    Departement universitaire de psychiatrie adulte, Universite de Lausanne, Clinique de Cery, Switzerland
    Schizophr Res 118:256-63. 2010
    ..To assess the prevalence and predictors of service disengagement in a treated epidemiological cohort of first-episode psychosis (FEP) patients...
  13. ncbi request reprint Pharmacological treatment in the early phase of bipolar disorders: what stage are we at?
    Philippe Conus
    Département Universitaire de Psychiatrie CHUV, Universite de Lausanne, Treatment and Early Intervention Program for Psychosis TIPP, Clinique de Cery, Prilly, Switzerland
    Aust N Z J Psychiatry 40:199-207. 2006
    ..To review available guidelines, explore treatment strategies currently applied, identify critical issues and propose direction for new developments...
  14. ncbi request reprint [The "SYNAPSY" project: where psychiatrists and neuroscientists meet]
    Philippe Conus
    Service de Psychiatrie Générale, Département de Psychiatrie CHUV, Site de Cery, 1008 Prilly
    Rev Med Suisse 7:1818-20, 1822-3. 2011
    ..On the basis of questions stemming from clinical practice and in the frame of patients cohorts, various research projects in neuroscience should lead to progresses that may have a considerable impact on clinical practice...
  15. ncbi request reprint [Early intervention in psychotic disorders: which role for primary care practitioners?]
    Philippe Conus
    DP CHUV, Clinique de Cery, 1008 Prilly
    Rev Med Suisse 1:2149-50, 2152-3. 2005
    ....
  16. ncbi request reprint Difficult-to-engage patients: a specific target for time-limited assertive outreach in a Swiss setting
    Charles Bonsack
    Unité de Psychiatrie Communautaire, Département de psychiatrie du CHUV, Faculté de Biologie et Médecine, Universite de Lausanne, Switzerland
    Can J Psychiatry 50:845-50. 2005
    ..This study aimed to evaluate the applicability and efficiency of time-limited ACT...
  17. pmc Impaired glutathione synthesis in schizophrenia: convergent genetic and functional evidence
    Rene Gysin
    Center for Psychiatric Neuroscience, Department of Psychiatry, University Hospital Center and University of Lausanne, 1008 Prilly Lausanne, Switzerland
    Proc Natl Acad Sci U S A 104:16621-6. 2007
    ..Taken together, the study provides genetic and functional evidence that an impaired capacity to synthesize GSH under conditions of oxidative stress is a vulnerability factor for schizophrenia...
  18. ncbi request reprint Setting the stage: from prodrome to treatment resistance in bipolar disorder
    Michael Berk
    Barwon Health and The Geelong Clinic, Geelong, Victoria, Australia
    Bipolar Disord 9:671-8. 2007
    ..At the other end of the spectrum, the model attempts to operationalize treatment resistance. The utility of the model will need to be validated by empirical research...
  19. ncbi request reprint Schneiderian first rank symptoms predict poor outcome within first episode manic psychosis
    Philippe Conus
    ORYGEN Research Centre, Parkville, Victoria, Australia
    J Affect Disord 81:259-68. 2004
    ..While some authors have found a correlation between such symptoms and outcome, their predictive value was rather limited in these studies...
  20. ncbi request reprint Early intervention in bipolar disorders: opportunities and pitfalls
    Michael Berk
    Barwon Health, University of Melbourne, Geelong, Vic, Australia
    Med J Aust 187:S11-4. 2007
    ..There is a need for early identification, and to develop treatments and services applicable to the specific needs of this population...
  21. doi request reprint N-acetyl cysteine as a glutathione precursor for schizophrenia--a double-blind, randomized, placebo-controlled trial
    Michael Berk
    The Mental Health Research Institute of Victoria, Parkville, Australia
    Biol Psychiatry 64:361-8. 2008
    ..This study was conducted to evaluate the safety and effectiveness of oral NAC (1 g orally twice daily [b.i.d.]) as an add-on to maintenance medication for the treatment of chronic schizophrenia over a 24-week period...
  22. doi request reprint Familial psychopathology in the First Episode Psychosis Outcome Study
    Katherine I Morley
    ORYGEN Research Centre, Department of Psychiatry, University of Melbourne, Victoria, Australia
    Aust N Z J Psychiatry 42:617-26. 2008
    ....
  23. doi request reprint Prevalence and predictors of suicide attempt in an incidence cohort of 661 young people with first-episode psychosis
    Jo Robinson
    Orygen Youth Health Research Centre, Parkville, Vic, Australia
    Aust N Z J Psychiatry 43:149-57. 2009
    ..The aims of the present study were therefore to examine the prevalence and predictors of suicide and suicide attempt before and during the first 18-24 months of treatment...
  24. ncbi request reprint [Early intervention for the initial phase of psychotic disorders in Lausanne: what problems and what solutions?]
    Philippe Conus
    Unité Minkovski, Departement universitaire de psychiatrie adulte, Site de Cery, 1008 Prilly
    Rev Med Suisse Romande 124:221-4. 2004
    ..It is however important to match them to local needs as well as to the structure of local health services. This paper reviews elements that justify such a development in Lausanne, Switzerland, and describe its various elements...
  25. doi request reprint Randomized controlled trial of interventions for young people at ultra-high risk of psychosis: study design and baseline characteristics
    Lisa J Phillips
    Department of Psychology, University of Melbourne, Melbourne, Victoria 3010, Australia
    Aust N Z J Psychiatry 43:818-29. 2009
    ..Results of three clinical trials have been published that provide mixed support for the effectiveness of psychological and pharmacological interventions in preventing the onset of psychotic disorder...
  26. ncbi request reprint [Access to care and maintenance in the community of persons who are difficult to engage in psychiatric treatment]
    Charles Bonsack
    Unité de Psychiatrie Communautaire, Departement universitaire de psychiatrie adulte, Site de Cery, 1008 Prilly
    Rev Med Suisse Romande 124:225-9. 2004
    ..Results and care's steps of intensive case management as practiced in Lausanne are described and illustrated with cases vignettes...
  27. doi request reprint Sudden death among young people with first-episode psychosis: An 8-10 year follow-up study
    Jo Robinson
    Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria 3052, Melbourne, Australia
    Psychiatry Res 177:305-8. 2010
    ..A previous suicide attempt was very common amongst those who died, suggesting that future research could focus upon the development of interventions for young people with FEP who engage in suicidal behaviour...
  28. ncbi request reprint First-episode mania: a neglected priority for early intervention
    Philippe Conus
    Early Psychosis Prevention and Intervention Centre, Parville, Victoria, Australia
    Aust N Z J Psychiatry 36:158-72. 2002
    ..This paper summarizes current knowledge about FE mania and explores the potential for early intervention...
  29. ncbi request reprint [Drugs and psychoses: what to do?]
    Philippe Conus
    Département Universitaire de Psychiatrie CHUV, Hôpital de Cery, 1008 Prilly, Suisse
    Rev Med Suisse Romande 124:149-51. 2004
    ..This paper reviews epidemiological and diagnostic elements, outlines the various treatment stages, the type of medication currently used in such situations and provides a brief description of motivational interview techniques...
  30. ncbi request reprint Readiness to participate in psychiatric research
    Daniele Zullino
    Psychiatric University Department for Adult Psychiatry, Clinique de Cery, CH 1008 Prilly Lausanne, Switzerland
    Can J Psychiatry 48:480-4. 2003
    ..Seeking patients' views about their experience in research projects may allow investigators to develop more effective recruitment and retention strategies...
  31. ncbi request reprint Pre-treatment, baseline, and outcome differences between early-onset and adult-onset psychosis in an epidemiological cohort of 636 first-episode patients
    Benno G Schimmelmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Virchowstr 174, 45147 Essen, Germany
    Schizophr Res 95:1-8. 2007
    ..To assess pre-treatment, baseline, and outcome differences of patients with early- (onset<age 18) and adult-onset (onset>or=age 18) psychosis in an epidemiological cohort of first-episode patients...
  32. ncbi request reprint Predictors of service disengagement in first-admitted adolescents with psychosis
    Benno Graf Schimmelmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Germany
    J Am Acad Child Adolesc Psychiatry 45:990-9. 2006
    ..To assess the risk and predictors of service disengagement in adolescents with first-episode psychosis (FEP) receiving their first treatment in a long-standing early intervention and prevention centre...
  33. ncbi request reprint Diagnostic stability 18 months after treatment initiation for first-episode psychosis
    Benno G Schimmelmann
    Centre for Psychosocial Medicine, Clinic for Child and Adolescent Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
    J Clin Psychiatry 66:1239-46. 2005
    ..2) Comparison between those patients who shifted from DSM-IV schizophreniform disorder to schizophrenia or schizo-affective disorder and those whose diagnosis of schizophreniform disorder remained stable...
  34. ncbi request reprint Pharmacotherapy of first-episode psychosis
    Martin Lambert
    Centre for Psychosocial Medicine, Clinic for Psychiatry and Psychotherapy of the University of Hamburg, Martinistreet 52, 20246 Hamburg, Germany
    Expert Opin Pharmacother 4:717-50. 2003
    ....
  35. doi request reprint Impact of duration of untreated psychosis on pre-treatment, baseline, and outcome characteristics in an epidemiological first-episode psychosis cohort
    Benno G Schimmelmann
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Virchowstrasse 174, 45147 Essen, Germany
    J Psychiatr Res 42:982-90. 2008
    ..To assess the impact of duration of untreated psychosis (DUP) on baseline and 18-month follow-up characteristics controlling for relevant confounders in an epidemiological first-episode psychosis (FEP) cohort...
  36. ncbi request reprint Glutathione precursor, N-acetyl-cysteine, improves mismatch negativity in schizophrenia patients
    Suzie Lavoie
    Center for Psychiatric Neuroscience, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Switzerland
    Neuropsychopharmacology 33:2187-99. 2008
    ..The improvement of this functional marker may indicate an important pathway towards new therapeutic strategies that target glutathione dysregulation in schizophrenia...