Research Topics
Genomes and Genes | Erich BrunnerSummaryCountry: Switzerland Publications
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Publications
Madm (Mlf1 adapter molecule) cooperates with Bunched A to promote growth in DrosophilaSilvia Gluderer
Institute of Molecular Systems Biology, ETH Zurich, Wolfgang Pauli Strasse 16, 8093 Zurich, Switzerland
J Biol 9:9. 2010..In Drosophila, the long isoform Bunched A (BunA) acts as a growth promoter, but how BunA controls growth has remained obscure...
A high-quality catalog of the Drosophila melanogaster proteomeErich Brunner
Center for Model Organism Proteomes, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
Nat Biotechnol 25:576-83. 2007..melanogaster gene models. This library of proteotypic peptides should enable fast, targeted and quantitative proteomic studies to elucidate the systems biology of this model organism...
Coop functions as a corepressor of Pangolin and antagonizes Wingless signalingHaiyun Song
Institute of Molecular Life Sciences, University of Zurich, CH 8057 Zurich, Switzerland
Genes Dev 24:881-6. 2010..Finally, we show that Coop antagonizes the binding of Armadillo to Pangolin, providing a mechanism for Coop-mediated repression of Wg target gene transcription...
Deterministic protein inference for shotgun proteomics data provides new insights into Arabidopsis pollen development and functionMonica A Grobei
Center for Model Organism Proteomes, University of Zurich, Switzerland
Genome Res 19:1786-800. 2009..Interestingly, the pollen proteome is most similar to that of seeds, indicating physiological similarities between these developmentally distinct tissues...
Generating and navigating proteome maps using mass spectrometryChristian H Ahrens
Quantitative Model Organism Proteomics, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
Nat Rev Mol Cell Biol 11:789-801. 2010..Achieving these goals will require complete proteome maps and analytical strategies that use these maps as prior information and will greatly enhance the impact of proteomics on biological and clinical research...
Comparative functional analysis of the Caenorhabditis elegans and Drosophila melanogaster proteomesSabine P Schrimpf
Institute of Molecular Biology, University of Zurich, Zurich, Switzerland
PLoS Biol 7:e48. 2009....
A proteome catalog of Drosophila melanogaster: an essential resource for targeted quantitative proteomicsChristian H Ahrens
Center for Model Organsim Proteomes, University of Zurich, Zurich, Switzerland
Fly (Austin) 1:182-6. 2007....
Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogasterSandra Goetze
Center for Model Organism Proteomes, University of Zurich, Switzerland
PLoS Biol 7:e1000236. 2009..Since the (X)PX rule seems to be of general validity in lower as well as higher eukaryotes, we propose that it can be used to study the function of N-terminal acetylation in all species...
Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complexThomas Kramps
Institut fur Molekularbiologie, Universitat Zurich, Winterthurerstrasse 190, CH 8057, Zurich, Switzerland
Cell 109:47-60. 2002....
Differential display and protein quantificationErich Brunner
Functional Genomics Center Zurich, Winterthurerstr 190, 8057 Zurich, Switzerland
EXS 97:115-40. 2007..In this chapter we review the current status of, and options for, protein quantification in high-throughput experiments and discuss the suitability and limitations of different existing methods...
Proteomic analysis of synaptosomes using isotope-coded affinity tags and mass spectrometrySabine P Schrimpf
Department of Biochemistry, University of Zurich, Zurich, Switzerland
Proteomics 5:2531-41. 2005..The results provide an inventory of the synaptic proteome and confirm the suitability of the ICAT method for the assessment of synaptic structure, function and plasticity...
Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometryFrank Desiere
Nestle Research Center, 1000 Lausanne 26, Switzerland
Genome Biol 6:R9. 2005..This resource could serve as an expandable repository for MS-derived proteome information...
Optimized peptide separation and identification for mass spectrometry based proteomics via free-flow electrophoresisJohan Malmstrom
Institute for Molecular Systems Molecular Biology, Swiss Federal Institute for Technology Zürich ETH, Hoenggerberg 8093 Zürich, Switzerland
J Proteome Res 5:2241-9. 2006....
