Cathrin Brisken

Summary

Country: Switzerland

Publications

  1. doi request reprint Perinatal exposure to bisphenol a increases adult mammary gland progesterone response and cell number
    Ayyakkannu Ayyanan
    ISREC Swiss Institute for Experimental Cancer Research, National Center of Competence Molecular Oncology, Lausanne, Switzerland
    Mol Endocrinol 25:1915-23. 2011
  2. pmc High hopes for RANKL: will the mouse model live up to its promise?
    Tamara Tanos
    Ecole Polytechnique Federale de Lausanne, ISREC Swiss Institute for Experimental Cancer Research, NCCR Molecular Oncology, SV2, 832 Station 19, CH 1015 Lausanne, Switzerland
    Breast Cancer Res 13:302. 2011
  3. doi request reprint Progesterone signalling in breast cancer: a neglected hormone coming into the limelight
    Cathrin Brisken
    ISREC Swiss Institute for Experimental Cancer Research, National Center of Competence for Molecular Oncology, School of Life Sciences, Ecole Polytechnique Federale de Lausanne EPFL, SV2 832 Station 19, CH 1015 Lausanne, Switzerland
    Nat Rev Cancer 13:385-96. 2013
  4. pmc Hormone action in the mammary gland
    Cathrin Brisken
    Ecole Polytechnique Federale de Lausanne EPFL, ISREC Swiss Institute for Experimental Cancer Research, NCCR Molecular Oncology, SV2 832 Station 19, CH 1015 Lausanne, Switzerland
    Cold Spring Harb Perspect Biol 2:a003178. 2010
  5. ncbi request reprint Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective
    Cathrin Brisken
    NCCR Molecular Oncology, Swiss Institute for Experimental Cancer Research ISREC, 155 Chemin des Boveresses, Epalinges s Lausanne, CH 1066, Switzerland
    Stem Cell Rev 3:147-56. 2007
  6. doi request reprint Progesterone/RANKL is a major regulatory axis in the human breast
    Tamara Tanos
    Swiss Institute for Experimental Cancer Research, National Center of Competence in Research Molecular Oncology, School of Life Sciences, Ecole Polytechnique Federale de Lausanne, CH 1015 Lausanne, Switzerland
    Sci Transl Med 5:182ra55. 2013
  7. ncbi request reprint What signals operate in the mammary niche?
    Tamara Tanos
    NCCR Molecular Oncology, Ecole Polytechnique Federale de Lausanne EPFL, ISREC Swiss Institute for Experimental Cancer Research, 155, Chemin des Boveresses, CH 1066 Epalinges, Switzerland
    Breast Dis 29:69-82. 2008
  8. doi request reprint Paracrine signaling by progesterone
    Renuga Devi Rajaram
    Ecole Polytechnique Federale de Lausanne, ISREC Swiss Institute for Experimental Cancer Research, NCCR Molecular Oncology, SV2832 Station 19, CH 1015 Lausanne, Switzerland
    Mol Cell Endocrinol 357:80-90. 2012
  9. doi request reprint Monitoring proliferative activities of hormone-like odorants in human breast cancer cells by gene transcription profiling and electrical impedance spectroscopy
    Horst Pick
    Laboratory of Physical Chemistry of Polymers and Membranes, Institute of Chemical Sciences and Engineering, Ecole Polytechnique Federale de Lausanne EPFL, CH 1015 Lausanne, Switzerland Electronic address
    Biosens Bioelectron 50:431-6. 2013
  10. pmc Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland
    Manfred Beleut
    Ecole Polytechnique Federale de Lausanne, Swiss Institute for Experimental Cancer Research ISREC, NCCR Molecular Oncology, CH 1015 Lausanne, Switzerland
    Proc Natl Acad Sci U S A 107:2989-94. 2010

Collaborators

Detail Information

Publications13

  1. doi request reprint Perinatal exposure to bisphenol a increases adult mammary gland progesterone response and cell number
    Ayyakkannu Ayyanan
    ISREC Swiss Institute for Experimental Cancer Research, National Center of Competence Molecular Oncology, Lausanne, Switzerland
    Mol Endocrinol 25:1915-23. 2011
    ..Thus, perinatal exposure to environmentally relevant doses of BPA alters long-term hormone response that may increase the propensity to develop breast cancer...
  2. pmc High hopes for RANKL: will the mouse model live up to its promise?
    Tamara Tanos
    Ecole Polytechnique Federale de Lausanne, ISREC Swiss Institute for Experimental Cancer Research, NCCR Molecular Oncology, SV2, 832 Station 19, CH 1015 Lausanne, Switzerland
    Breast Cancer Res 13:302. 2011
    ....
  3. doi request reprint Progesterone signalling in breast cancer: a neglected hormone coming into the limelight
    Cathrin Brisken
    ISREC Swiss Institute for Experimental Cancer Research, National Center of Competence for Molecular Oncology, School of Life Sciences, Ecole Polytechnique Federale de Lausanne EPFL, SV2 832 Station 19, CH 1015 Lausanne, Switzerland
    Nat Rev Cancer 13:385-96. 2013
    ..If the findings in the mouse model translate to humans, new preventive and therapeutic perspectives might open up...
  4. pmc Hormone action in the mammary gland
    Cathrin Brisken
    Ecole Polytechnique Federale de Lausanne EPFL, ISREC Swiss Institute for Experimental Cancer Research, NCCR Molecular Oncology, SV2 832 Station 19, CH 1015 Lausanne, Switzerland
    Cold Spring Harb Perspect Biol 2:a003178. 2010
    ..Tissue and stage specificity of hormonal signaling is achieved at the molecular level by different chromatin contexts and differential recruitment of coactivators and corepressors...
  5. ncbi request reprint Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective
    Cathrin Brisken
    NCCR Molecular Oncology, Swiss Institute for Experimental Cancer Research ISREC, 155 Chemin des Boveresses, Epalinges s Lausanne, CH 1066, Switzerland
    Stem Cell Rev 3:147-56. 2007
    ....
  6. doi request reprint Progesterone/RANKL is a major regulatory axis in the human breast
    Tamara Tanos
    Swiss Institute for Experimental Cancer Research, National Center of Competence in Research Molecular Oncology, School of Life Sciences, Ecole Polytechnique Federale de Lausanne, CH 1015 Lausanne, Switzerland
    Sci Transl Med 5:182ra55. 2013
    ..Thus, important hormonal control mechanisms are conserved across species, making RANKL a potential target in breast cancer treatment and prevention...
  7. ncbi request reprint What signals operate in the mammary niche?
    Tamara Tanos
    NCCR Molecular Oncology, Ecole Polytechnique Federale de Lausanne EPFL, ISREC Swiss Institute for Experimental Cancer Research, 155, Chemin des Boveresses, CH 1066 Epalinges, Switzerland
    Breast Dis 29:69-82. 2008
    ..Some of the downstream mediators are in common with other niches such as Wnt and possibly Notch signaling. Other signals are specific to the mammary gland such as amphiregulin and RANKL...
  8. doi request reprint Paracrine signaling by progesterone
    Renuga Devi Rajaram
    Ecole Polytechnique Federale de Lausanne, ISREC Swiss Institute for Experimental Cancer Research, NCCR Molecular Oncology, SV2832 Station 19, CH 1015 Lausanne, Switzerland
    Mol Cell Endocrinol 357:80-90. 2012
    ..Evidence is forthcoming that the intercellular signaling pathways that control development and physiological functions are important in tumorigenesis...
  9. doi request reprint Monitoring proliferative activities of hormone-like odorants in human breast cancer cells by gene transcription profiling and electrical impedance spectroscopy
    Horst Pick
    Laboratory of Physical Chemistry of Polymers and Membranes, Institute of Chemical Sciences and Engineering, Ecole Polytechnique Federale de Lausanne EPFL, CH 1015 Lausanne, Switzerland Electronic address
    Biosens Bioelectron 50:431-6. 2013
    ..Though ERα exhibits complex regulatory roles our non-invasive approach captures its activity for accelerated screenings of compounds promoting breast cancer cell proliferation expanding the analysis of ERα signaling networks...
  10. pmc Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland
    Manfred Beleut
    Ecole Polytechnique Federale de Lausanne, Swiss Institute for Experimental Cancer Research ISREC, NCCR Molecular Oncology, CH 1015 Lausanne, Switzerland
    Proc Natl Acad Sci U S A 107:2989-94. 2010
    ..Thus, progesterone elicits proliferation by a cell-intrinsic and a, more important, paracrine mechanism...
  11. pmc From normal cell types to malignant phenotypes
    Ozden Yalcin-Ozuysal
    Ecole Polytechnique Federale de Lausanne, ISREC Swiss Institute for Experimental Cancer Research, CH 1015 Lausanne, Switzerland
    Breast Cancer Res 11:306. 2009
    ..Recent work challenges this view by providing evidence that luminal precursor cells are involved in the pathogenesis of basal breast cancers and has made new links between normal cell populations and molecular tumor phenotypes...
  12. pmc An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells
    Stephan Duss
    NCCR Molecular Oncology, Swiss Institute for Experimental Cancer Research ISREC, Chemin des Boveresses 155, CH 1066 Epalinges, Switzerland
    Breast Cancer Res 9:R38. 2007
    ..To create an ERalpha-positive breast cancer model, we have forced normal HMECs derived from reduction mammoplasty tissue to express ERalpha in combination with other relevant breast cancer genes...