Stephanie Blum

Summary

Country: Switzerland

Publications

  1. ncbi Probiotics and immune response
    Stephanie Blum
    Nestle Research Center, P O Box 44, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    Clin Rev Allergy Immunol 22:287-309. 2002
  2. ncbi Intestinal microflora and homeostasis of the mucosal immune response: implications for probiotic bacteria?
    Stephanie Blum
    Nestle Research Centre, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    Curr Issues Intest Microbiol 4:53-60. 2003
  3. doi Intake of a milk-based wolfberry formulation enhances the immune response of young-adult and aged mice
    Karine Vidal
    Nutrition and Health Department, Nestle Research Center, Lausanne, Switzerland
    Rejuvenation Res 13:47-53. 2010
  4. pmc Anti-inflammatory effects of Lacto-Wolfberry in a mouse model of experimental colitis
    David Philippe
    Department of Nutrition and Health, Nestle Research Center, CH 1000 Lausanne, Switzerland
    World J Gastroenterol 18:5351-9. 2012
  5. pmc Bifidobacterium lactis attenuates onset of inflammation in a murine model of colitis
    David Philippe
    Department of Nutrition and Health, Nestle Research Centre, Vers chez les Blanc, Lausanne 26, Switzerland
    World J Gastroenterol 17:459-69. 2011
  6. pmc Lactobacillus paracasei reduces intestinal inflammation in adoptive transfer mouse model of experimental colitis
    Manuel Oliveira
    Nutrition and Health Department, Nestle Research Center, CH 1000 Lausanne, Switzerland
    Clin Dev Immunol 2011:807483. 2011
  7. doi Effect of Lactobacillus paracasei NCC2461 on antigen-specific T-cell mediated immune responses in aged mice
    Karine Vidal
    Nutrition and Health Department, Nestle Research Center, Lausanne, Switzerland
    Rejuvenation Res 11:957-64. 2008
  8. pmc Divergent patterns of colonization and immune response elicited from two intestinal Lactobacillus strains that display similar properties in vitro
    Nabila Ibnou-Zekri
    Department of Biosciences, Nestle Research Center, Lausanne, Switzerland
    Infect Immun 71:428-36. 2003
  9. ncbi Supplementation with oral probiotic bacteria maintains cutaneous immune homeostasis after UV exposure
    Audrey Gueniche
    Nestle Research Center, Vers chez les Blanc, PO Box 44, CH 1000, Lausanne 26, Switzerland
    Eur J Dermatol 16:511-7. 2006
  10. ncbi Feeding a diet containing a fructooligosaccharide mix can enhance Salmonella vaccine efficacy in mice
    Jalil Benyacoub
    Nestle Research Center, CH 1000, Lausanne 26, Switzerland
    J Nutr 138:123-9. 2008

Collaborators

Detail Information

Publications20

  1. ncbi Probiotics and immune response
    Stephanie Blum
    Nestle Research Center, P O Box 44, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    Clin Rev Allergy Immunol 22:287-309. 2002
  2. ncbi Intestinal microflora and homeostasis of the mucosal immune response: implications for probiotic bacteria?
    Stephanie Blum
    Nestle Research Centre, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
    Curr Issues Intest Microbiol 4:53-60. 2003
    ....
  3. doi Intake of a milk-based wolfberry formulation enhances the immune response of young-adult and aged mice
    Karine Vidal
    Nutrition and Health Department, Nestle Research Center, Lausanne, Switzerland
    Rejuvenation Res 13:47-53. 2010
    ..In conclusion, dietary intake of Lacto-Wolfberry may favorably modulate the poor responsiveness to antigenic challenge observed with aging...
  4. pmc Anti-inflammatory effects of Lacto-Wolfberry in a mouse model of experimental colitis
    David Philippe
    Department of Nutrition and Health, Nestle Research Center, CH 1000 Lausanne, Switzerland
    World J Gastroenterol 18:5351-9. 2012
    ..To investigate the anti-inflammatory properties of Lacto-Wolfberry (LWB), both in vitro and using a mouse model of experimental colitis...
  5. pmc Bifidobacterium lactis attenuates onset of inflammation in a murine model of colitis
    David Philippe
    Department of Nutrition and Health, Nestle Research Centre, Vers chez les Blanc, Lausanne 26, Switzerland
    World J Gastroenterol 17:459-69. 2011
    ..To assess the anti-inflammatory effect of the probiotic Bifidobacterium lactis (B. lactis) in an adoptive transfer model of colitis...
  6. pmc Lactobacillus paracasei reduces intestinal inflammation in adoptive transfer mouse model of experimental colitis
    Manuel Oliveira
    Nutrition and Health Department, Nestle Research Center, CH 1000 Lausanne, Switzerland
    Clin Dev Immunol 2011:807483. 2011
    ..We conclude that probiotics such as Lactobacillus paracasei harbor worthwhile in vivo immunomodulatory properties to prevent intestinal inflammation by nutritional approaches...
  7. doi Effect of Lactobacillus paracasei NCC2461 on antigen-specific T-cell mediated immune responses in aged mice
    Karine Vidal
    Nutrition and Health Department, Nestle Research Center, Lausanne, Switzerland
    Rejuvenation Res 11:957-64. 2008
    ..The poor responsiveness to antigenic challenge, frequently observed in elderly people, may be improved by supplementation with L. paracasei NCC2461...
  8. pmc Divergent patterns of colonization and immune response elicited from two intestinal Lactobacillus strains that display similar properties in vitro
    Nabila Ibnou-Zekri
    Department of Biosciences, Nestle Research Center, Lausanne, Switzerland
    Infect Immun 71:428-36. 2003
    ..Therefore, despite similar in vitro probiotic properties, distinct Lactobacillus strains may colonize the gut differently and generate divergent immune responses...
  9. ncbi Supplementation with oral probiotic bacteria maintains cutaneous immune homeostasis after UV exposure
    Audrey Gueniche
    Nestle Research Center, Vers chez les Blanc, PO Box 44, CH 1000, Lausanne 26, Switzerland
    Eur J Dermatol 16:511-7. 2006
    ..In conclusion, our data demonstrate that ingested probiotic bacteria can maintain cutaneous immune capacity after UV exposure...
  10. ncbi Feeding a diet containing a fructooligosaccharide mix can enhance Salmonella vaccine efficacy in mice
    Jalil Benyacoub
    Nestle Research Center, CH 1000, Lausanne 26, Switzerland
    J Nutr 138:123-9. 2008
    ..Overall, the data suggest that a diet supplemented with FOS:inulin mix stimulates mucosal immunity and seems to improve efficacy of an oral vaccine...
  11. ncbi IL-10 producing CD14low monocytes inhibit lymphocyte-dependent activation of intestinal epithelial cells by commensal bacteria
    Dirk Haller
    Department of Immunology, Nestle Research Centre, Vers chez les Blanc, Lausanne, Switzerland
    Microbiol Immunol 46:195-205. 2002
    ..These results strengthen the hypothesis that the gut epithelium constitutes an important functional element in the regulation of mucosal immune homeostasis towards commensal bacteria...
  12. ncbi Probiotics as a treatment strategy for gastrointestinal diseases?
    Gabriela E Bergonzelli
    Nestle Research Center, PO Box 44, CH 1000 Lausanne 26, Switzerland
    Digestion 72:57-68. 2005
    ..However, accumulated data is encouraging and suggests that efficacy is strain-dependent. Finally, too few probiotic intervention trials have been reported on colon cancer to allow any firm conclusion...
  13. ncbi Milk casein-based diet containing TGF-beta controls the inflammatory reaction in the HLA-B27 transgenic rat model
    Eduardo J Schiffrin
    Nestle Research Center, Nestec Ltd, Lausanne, Switzerland
    JPEN J Parenter Enteral Nutr 29:S141-8; discussion S149-50, S184-8. 2005
    ..We have examined the capacity of a TGF-beta containing diet to control the intestinal inflammation in HLA-B27 transgenic rats, and compared its effects with a similar diet devoid of TGF-beta...
  14. doi Metabolic assessment of gradual development of moderate experimental colitis in IL-10 deficient mice
    Francois Pierre J Martin
    Nestle Research Center, P O Box 44, Vers chez les Blanc, CH 1000 Lausanne 26, Switzerland
    J Proteome Res 8:2376-87. 2009
    ..These integrated system investigations demonstrate the potential of metabonomics for investigating the mechanistic basis of IBD, and it will provide novel avenues for management of IBD...
  15. ncbi Improvement of the human intestinal flora by ingestion of the probiotic strain Lactobacillus johnsonii La1
    Toshihiko Yamano
    Showa Women s University, 1 7 Taishidou, Setagayaku, Tokyo, 154 8533, Japan
    Br J Nutr 95:303-12. 2006
    ..L. johnsonii La1 was identified in all subjects only after the consumption of the fermented milk. These results suggest that L. johnsonii La1 can contribute to improve intestinal microflora with probiotic properties...
  16. doi Prophylactic effect of oral administration of Lactobacillus johnsonii NCC533 (La1) during the weaning period on atopic dermatitis in NC/NgaTnd mice
    Akane Tanaka
    Laboratory of Veterinary Molecular Pathology and Therapeutics, Division of Animal Life Science, Graduate School, Institute of Symbiotic Science and Technology, Tokyo University of Agriculture and Technology, 3 5 8 Saiwai cho, Fuchu, Tokyo 183 8509, Japan
    Eur J Dermatol 18:136-40. 2008
    ..This study showed that exposure to La1 from the early stages might be beneficial to reduce the exacerbation of AD in children at high-risk of allergy...
  17. ncbi Anti-inflammatory effects of bifidobacteria by inhibition of LPS-induced NF-kappaB activation
    Christian U Riedel
    Department of Microbiology and Biotechnology, University of Ulm, Germany
    World J Gastroenterol 12:3729-35. 2006
    ..Different strains of bifidobacteria were analysed for their effects on HT-29 intestinal epithelial cells (IECs) in in vitro models both of the non-inflamed and inflamed intestinal epithelium...
  18. ncbi Presence of low-grade inflammation in old rats does not worsen skeletal muscle loss under an endotoxemic and dietary stress
    Gilles Mayot
    INRA, Centre Clermont Ferrand Theix, UMR 1019 Unite de Nutrition Humaine, F 63122 Saint Genes Champanelle, France
    Exp Gerontol 42:1167-75. 2007
    ..These results extend and support our previous findings by demonstrating that age-associated low-grade inflammation does not aggravate sarcopenia in old rats...
  19. ncbi Interaction of bifidobacteria with Caco-2 cells-adhesion and impact on expression profiles
    Christian U Riedel
    Department of Microbiology and Biotechnology, University of Ulm, 89068 Ulm, Germany
    Int J Food Microbiol 110:62-8. 2006
    ..coli D2241 or B. bifidum S17 was observed for various immune markers. The presented results suggest that Caco-2 cells might be specifically unresponsive to challenge with bifidobacteria irrespective of the level of adhesion...
  20. pmc Lactobacillus johnsonii La1 antagonizes Giardia intestinalis in vivo
    Martín A Humen
    CIDCA, Universidad Nacional de La Plata, Calle 47 y 116 CC 553, 1900 La Plata, Argentina
    Infect Immun 73:1265-9. 2005
    ..Results show for the first time the antigiardial effect of probiotic lactobacilli in vivo and provide further insight into the antagonistic properties of lactic acid bacteria against protozoa involved in intestinal infections...