- Probiotics and immune responseStephanie Blum
Nestle Research Center, P O Box 44, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
Clin Rev Allergy Immunol 22:287-309. 2002
- Intestinal microflora and homeostasis of the mucosal immune response: implications for probiotic bacteria?Stephanie Blum
Nestle Research Centre, Vers chez les Blanc, 1000 Lausanne 26, Switzerland
Curr Issues Intest Microbiol 4:53-60. 2003....
- Intake of a milk-based wolfberry formulation enhances the immune response of young-adult and aged miceKarine Vidal
Nutrition and Health Department, Nestle Research Center, Lausanne, Switzerland
Rejuvenation Res 13:47-53. 2010..In conclusion, dietary intake of Lacto-Wolfberry may favorably modulate the poor responsiveness to antigenic challenge observed with aging...
- Anti-inflammatory effects of Lacto-Wolfberry in a mouse model of experimental colitisDavid Philippe
Department of Nutrition and Health, Nestle Research Center, CH 1000 Lausanne, Switzerland
World J Gastroenterol 18:5351-9. 2012..To investigate the anti-inflammatory properties of Lacto-Wolfberry (LWB), both in vitro and using a mouse model of experimental colitis...
- Bifidobacterium lactis attenuates onset of inflammation in a murine model of colitisDavid Philippe
Department of Nutrition and Health, Nestle Research Centre, Vers chez les Blanc, Lausanne 26, Switzerland
World J Gastroenterol 17:459-69. 2011..To assess the anti-inflammatory effect of the probiotic Bifidobacterium lactis (B. lactis) in an adoptive transfer model of colitis...
- Lactobacillus paracasei reduces intestinal inflammation in adoptive transfer mouse model of experimental colitisManuel Oliveira
Nutrition and Health Department, Nestle Research Center, CH 1000 Lausanne, Switzerland
Clin Dev Immunol 2011:807483. 2011..We conclude that probiotics such as Lactobacillus paracasei harbor worthwhile in vivo immunomodulatory properties to prevent intestinal inflammation by nutritional approaches...
- Effect of Lactobacillus paracasei NCC2461 on antigen-specific T-cell mediated immune responses in aged miceKarine Vidal
Nutrition and Health Department, Nestle Research Center, Lausanne, Switzerland
Rejuvenation Res 11:957-64. 2008..The poor responsiveness to antigenic challenge, frequently observed in elderly people, may be improved by supplementation with L. paracasei NCC2461...
- Divergent patterns of colonization and immune response elicited from two intestinal Lactobacillus strains that display similar properties in vitroNabila Ibnou-Zekri
Department of Biosciences, Nestle Research Center, Lausanne, Switzerland
Infect Immun 71:428-36. 2003..Therefore, despite similar in vitro probiotic properties, distinct Lactobacillus strains may colonize the gut differently and generate divergent immune responses...
- Supplementation with oral probiotic bacteria maintains cutaneous immune homeostasis after UV exposureAudrey Gueniche
Nestle Research Center, Vers chez les Blanc, PO Box 44, CH 1000, Lausanne 26, Switzerland
Eur J Dermatol 16:511-7. 2006..In conclusion, our data demonstrate that ingested probiotic bacteria can maintain cutaneous immune capacity after UV exposure...
- Feeding a diet containing a fructooligosaccharide mix can enhance Salmonella vaccine efficacy in miceJalil Benyacoub
Nestle Research Center, CH 1000, Lausanne 26, Switzerland
J Nutr 138:123-9. 2008..Overall, the data suggest that a diet supplemented with FOS:inulin mix stimulates mucosal immunity and seems to improve efficacy of an oral vaccine...
- IL-10 producing CD14low monocytes inhibit lymphocyte-dependent activation of intestinal epithelial cells by commensal bacteriaDirk Haller
Department of Immunology, Nestle Research Centre, Vers chez les Blanc, Lausanne, Switzerland
Microbiol Immunol 46:195-205. 2002..These results strengthen the hypothesis that the gut epithelium constitutes an important functional element in the regulation of mucosal immune homeostasis towards commensal bacteria...
- Probiotics as a treatment strategy for gastrointestinal diseases?Gabriela E Bergonzelli
Nestle Research Center, PO Box 44, CH 1000 Lausanne 26, Switzerland
Digestion 72:57-68. 2005..However, accumulated data is encouraging and suggests that efficacy is strain-dependent. Finally, too few probiotic intervention trials have been reported on colon cancer to allow any firm conclusion...
- Milk casein-based diet containing TGF-beta controls the inflammatory reaction in the HLA-B27 transgenic rat modelEduardo J Schiffrin
Nestle Research Center, Nestec Ltd, Lausanne, Switzerland
JPEN J Parenter Enteral Nutr 29:S141-8; discussion S149-50, S184-8. 2005..We have examined the capacity of a TGF-beta containing diet to control the intestinal inflammation in HLA-B27 transgenic rats, and compared its effects with a similar diet devoid of TGF-beta...
- Metabolic assessment of gradual development of moderate experimental colitis in IL-10 deficient miceFrancois Pierre J Martin
Nestle Research Center, P O Box 44, Vers chez les Blanc, CH 1000 Lausanne 26, Switzerland
J Proteome Res 8:2376-87. 2009..These integrated system investigations demonstrate the potential of metabonomics for investigating the mechanistic basis of IBD, and it will provide novel avenues for management of IBD...
- Improvement of the human intestinal flora by ingestion of the probiotic strain Lactobacillus johnsonii La1Toshihiko Yamano
Showa Women s University, 1 7 Taishidou, Setagayaku, Tokyo, 154 8533, Japan
Br J Nutr 95:303-12. 2006..L. johnsonii La1 was identified in all subjects only after the consumption of the fermented milk. These results suggest that L. johnsonii La1 can contribute to improve intestinal microflora with probiotic properties...
- Prophylactic effect of oral administration of Lactobacillus johnsonii NCC533 (La1) during the weaning period on atopic dermatitis in NC/NgaTnd miceAkane Tanaka
Laboratory of Veterinary Molecular Pathology and Therapeutics, Division of Animal Life Science, Graduate School, Institute of Symbiotic Science and Technology, Tokyo University of Agriculture and Technology, 3 5 8 Saiwai cho, Fuchu, Tokyo 183 8509, Japan
Eur J Dermatol 18:136-40. 2008..This study showed that exposure to La1 from the early stages might be beneficial to reduce the exacerbation of AD in children at high-risk of allergy...
- Anti-inflammatory effects of bifidobacteria by inhibition of LPS-induced NF-kappaB activationChristian U Riedel
Department of Microbiology and Biotechnology, University of Ulm, Germany
World J Gastroenterol 12:3729-35. 2006..Different strains of bifidobacteria were analysed for their effects on HT-29 intestinal epithelial cells (IECs) in in vitro models both of the non-inflamed and inflamed intestinal epithelium...
- Presence of low-grade inflammation in old rats does not worsen skeletal muscle loss under an endotoxemic and dietary stressGilles Mayot
INRA, Centre Clermont Ferrand Theix, UMR 1019 Unite de Nutrition Humaine, F 63122 Saint Genes Champanelle, France
Exp Gerontol 42:1167-75. 2007..These results extend and support our previous findings by demonstrating that age-associated low-grade inflammation does not aggravate sarcopenia in old rats...
- Interaction of bifidobacteria with Caco-2 cells-adhesion and impact on expression profilesChristian U Riedel
Department of Microbiology and Biotechnology, University of Ulm, 89068 Ulm, Germany
Int J Food Microbiol 110:62-8. 2006..coli D2241 or B. bifidum S17 was observed for various immune markers. The presented results suggest that Caco-2 cells might be specifically unresponsive to challenge with bifidobacteria irrespective of the level of adhesion...
- Lactobacillus johnsonii La1 antagonizes Giardia intestinalis in vivoMartín A Humen
CIDCA, Universidad Nacional de La Plata, Calle 47 y 116 CC 553, 1900 La Plata, Argentina
Infect Immun 73:1265-9. 2005..Results show for the first time the antigiardial effect of probiotic lactobacilli in vivo and provide further insight into the antagonistic properties of lactic acid bacteria against protozoa involved in intestinal infections...