V Dietz

Summary

Affiliation: Balgrist University Hospital
Country: Switzerland

Publications

  1. ncbi request reprint Good clinical practice in neurorehabilitation
    Volker Dietz
    Lancet Neurol 5:377-8. 2006
  2. doi request reprint Human bipeds use quadrupedal coordination during locomotion
    Volker Dietz
    Balgrist University Hospital, Spinal Cord Injury Center, Forchstrasse 340, Zurich, Switzerland
    Ann N Y Acad Sci 1164:97-103. 2009
  3. pmc Standardized voluntary force measurement in a lower extremity rehabilitation robot
    Marc Bolliger
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    J Neuroeng Rehabil 5:23. 2008
  4. doi request reprint Locomotion in Parkinson's disease: neuronal coupling of upper and lower limbs
    V Dietz
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Brain 131:3421-31. 2008
  5. pmc G. Heiner Sell memorial lecture: neuronal plasticity after spinal cord injury: significance for present and future treatments
    Volker Dietz
    Spinal Cord Injury Center, University Hospital Balgrist, Zurich, Switzerland
    J Spinal Cord Med 29:481-8. 2006
  6. doi request reprint Body weight supported gait training: from laboratory to clinical setting
    V Dietz
    University Hospital Balgrist, Spinal Cord Injury Center, Forchstr 340, Ch 8008 Zurich, Switzerland
    Brain Res Bull 76:459-63. 2008
  7. ncbi request reprint Ready for human spinal cord repair?
    Volker Dietz
    Spinal Cord Injury Centre, Balgrist University Hospital, Forchstr 340 8008 Zürich, Switzerland
    Brain 131:2240-2. 2008
  8. ncbi request reprint Neurological aspects of spinal-cord repair: promises and challenges
    Volker Dietz
    Spinal Cord Injury Centre, University Hospital Balgrist, Zurich, Switzerland
    Lancet Neurol 5:688-94. 2006
  9. doi request reprint Body weight supported gait training: from laboratory to clinical setting
    V Dietz
    University Hospital Balgrist, Spinal Cord Injury Center, Zurich, Switzerland
    Brain Res Bull 78:I-VI. 2009
  10. ncbi request reprint Spastic movement disorder: impaired reflex function and altered muscle mechanics
    Volker Dietz
    Spinal Cord Injury Centre, University of Zurich, Switzerland
    Lancet Neurol 6:725-33. 2007

Detail Information

Publications103 found, 100 shown here

  1. ncbi request reprint Good clinical practice in neurorehabilitation
    Volker Dietz
    Lancet Neurol 5:377-8. 2006
  2. doi request reprint Human bipeds use quadrupedal coordination during locomotion
    Volker Dietz
    Balgrist University Hospital, Spinal Cord Injury Center, Forchstrasse 340, Zurich, Switzerland
    Ann N Y Acad Sci 1164:97-103. 2009
    ..During obstacle avoidance steps, an anticipatory quadrupedal limb coordination is up-regulated, with an involvement of proximal arm muscles during the acquisition and performance of this precision locomotor task...
  3. pmc Standardized voluntary force measurement in a lower extremity rehabilitation robot
    Marc Bolliger
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    J Neuroeng Rehabil 5:23. 2008
    ..A new method to assess isometric muscle force was implemented in the driven gait orthosis (DGO) Lokomat. To evaluate the capabilities of this new measurement method, inter- and intra-rater reliability were assessed...
  4. doi request reprint Locomotion in Parkinson's disease: neuronal coupling of upper and lower limbs
    V Dietz
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Brain 131:3421-31. 2008
    ..In the tibialis anterior the SR is attenuated presumably because of a stronger voluntary (i.e. cortical) control of leg movements...
  5. pmc G. Heiner Sell memorial lecture: neuronal plasticity after spinal cord injury: significance for present and future treatments
    Volker Dietz
    Spinal Cord Injury Center, University Hospital Balgrist, Zurich, Switzerland
    J Spinal Cord Med 29:481-8. 2006
    ....
  6. doi request reprint Body weight supported gait training: from laboratory to clinical setting
    V Dietz
    University Hospital Balgrist, Spinal Cord Injury Center, Forchstr 340, Ch 8008 Zurich, Switzerland
    Brain Res Bull 76:459-63. 2008
    ..Presently, individuals with complete SCI, spinal neuronal circuits undergo a degradation of their function 1 year after injury...
  7. ncbi request reprint Ready for human spinal cord repair?
    Volker Dietz
    Spinal Cord Injury Centre, Balgrist University Hospital, Forchstr 340 8008 Zürich, Switzerland
    Brain 131:2240-2. 2008
  8. ncbi request reprint Neurological aspects of spinal-cord repair: promises and challenges
    Volker Dietz
    Spinal Cord Injury Centre, University Hospital Balgrist, Zurich, Switzerland
    Lancet Neurol 5:688-94. 2006
    ..The relevance of this degradation for a regeneration-inducing treatment needs to be investigated. Fifth, the prerequisites to enable appropriate reconnection of regenerating tract fibres in a postacute stage have still to be established...
  9. doi request reprint Body weight supported gait training: from laboratory to clinical setting
    V Dietz
    University Hospital Balgrist, Spinal Cord Injury Center, Zurich, Switzerland
    Brain Res Bull 78:I-VI. 2009
    ..Presently, individuals with complete SCI, spinal neuronal circuits undergo a degradation of their function 1 year after injury...
  10. ncbi request reprint Spastic movement disorder: impaired reflex function and altered muscle mechanics
    Volker Dietz
    Spinal Cord Injury Centre, University of Zurich, Switzerland
    Lancet Neurol 6:725-33. 2007
    ..Antispastic drugs can accentuate paresis and therefore should be applied with caution in mobile patients...
  11. doi request reprint Changes in spinal reflex and locomotor activity after a complete spinal cord injury: a common mechanism?
    V Dietz
    Spinal Cord Injury Centre, University Hospital Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland
    Brain 132:2196-205. 2009
    ..These findings should be taken into consideration in the development of novel rehabilitation schemes and programs to facilitate regeneration-inducing therapies in spinal cord injury subjects...
  12. doi request reprint Modulation of spinal reflex by assisted locomotion in humans with chronic complete spinal cord injury
    M Bolliger
    Balgrist University Hospital, Zurich, Switzerland
    Clin Neurophysiol 121:2152-8. 2010
    ..Here we report on the modulation of SR by assisted locomotion in healthy and chronic motor cSCI subjects...
  13. doi request reprint Vertical perturbations of human gait: organisation and adaptation of leg muscle responses
    V Bachmann
    Spinal Cord Injury Center, University Hospital Balgrist, Forchstrasse 340, 8008, Zurich, Switzerland
    Exp Brain Res 186:123-30. 2008
    ..This is assumed to be due to the required compensation of the perturbations by polysynaptic spinal reflexes released following the perturbations. The findings underline the importance of load receptor input for the control of locomotion...
  14. ncbi request reprint Treadmill training in incomplete spinal cord injured rats
    K Fouad
    Brain Research Institute, University and ETH Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland
    Behav Brain Res 115:107-13. 2000
    ..It is probable that the spared ventral and ventro-lateral fibers allowed spontaneous recovery and 'self-training' to occur to such an extend that systematic treadmill training did not provide additional improvement...
  15. doi request reprint Clinical algorithm for improved prediction of ambulation and patient stratification after incomplete spinal cord injury
    Björn Zörner
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    J Neurotrauma 27:241-52. 2010
    ..These data provide evidence that a combination of predictors enables a reliable prediction of walking function and early patient stratification for clinical trials in miSCI...
  16. doi request reprint Obstacle stepping in children: task acquisition and performance
    J Michel
    Spinal Cord Injury Center, Balgrist University Hospital Zurich, Zurich, Switzerland
    Gait Posture 31:341-6. 2010
    ..Finally, ZNA tests can improve the prediction of complex adaptive locomotor behaviour compared to calendar age alone...
  17. ncbi request reprint Locomotor capacity and recovery of spinal cord function in paraplegic patients: a clinical and electrophysiological evaluation
    V Dietz
    Swiss Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    Electroencephalogr Clin Neurophysiol 109:140-53. 1998
    ..The findings of this study may be relevant for future clinical treatment of paraplegic patients...
  18. ncbi request reprint Limits of locomotor ability in subjects with a spinal cord injury
    H J A van Hedel
    1Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Spinal Cord 43:593-603. 2005
    ..Case-control study with pair-wise matching...
  19. doi request reprint Recovery from a spinal cord injury: significance of compensation, neural plasticity, and repair
    Armin Curt
    Spinal Cord Injury Centre, Balgrist University Hospital, Forchstrasse 340, Zurich, Switzerland
    J Neurotrauma 25:677-85. 2008
    ..These findings support the assumption that functional recovery occurs by compensation, especially in cSCI and by neural plasticity leading to a greater improvement in iSCI. Relevant repair of damaged spinal pathways does not take place...
  20. ncbi request reprint Degradation of neuronal function following a spinal cord injury: mechanisms and countermeasures
    Volker Dietz
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich, Switzerland
    Brain 127:2221-31. 2004
    ..This might be achieved by a continuous training approach starting early after injury...
  21. doi request reprint Modulation of spinal neuronal excitability by spinal direct currents and locomotion after spinal cord injury
    M Hubli
    Spinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland
    Clin Neurophysiol 124:1187-95. 2013
    ..We applied transcutaneous spinal direct current stimulation (tsDCS) and locomotor activity, to determine whether the excitability of spinal neuronal circuitries underlying locomotion can be modulated after motor complete SCI...
  22. ncbi request reprint Modulation of locomotor activity in complete spinal cord injury
    L Lunenburger
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Exp Brain Res 174:638-46. 2006
    ..The application of various speeds might enhance the effect of locomotor training in incomplete SCI subjects...
  23. ncbi request reprint Level of spinal cord lesion determines locomotor activity in spinal man
    V Dietz
    Swiss Paraplegic Centre, University Hospital Balgrist, Forchstr 340, Ch 8008 Zurich, Switzerland
    Exp Brain Res 128:405-9. 1999
    ....
  24. ncbi request reprint Facilitation of spinal reflexes assists performing but not learning an obstacle-avoidance locomotor task
    J Michel
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    Eur J Neurosci 26:1299-306. 2007
    ..This facilitation might provide assistance in safe obstacle stepping, e.g. to compensate quickly if resistance is encountered...
  25. ncbi request reprint Neuronal coordination of arm and leg movements during human locomotion
    V Dietz
    ParaCare, Paraplegic Centre University Hospital Balgrist, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    Eur J Neurosci 14:1906-14. 2001
    ..The results are compatible with the assumption that the proximal arm muscle responses are associated with the swinging of the arms during gait, as a residual function of quadrupedal locomotion...
  26. doi request reprint Influence of spinal reflexes on the locomotor pattern after spinal cord injury
    M Hubli
    Spinal Cord Injury Centre, University Hospital Balgrist, Zurich, Switzerland
    Gait Posture 34:409-14. 2011
    ..It is proposed that the two SR components have different physiological roles during locomotion...
  27. doi request reprint Obstacle stepping involves spinal anticipatory activity associated with quadrupedal limb coordination
    J Michel
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    Eur J Neurosci 27:1867-75. 2008
    ..This is presumably achieved by an up-regulated activity of coupled cervico-thoracal interneuronal circuits...
  28. ncbi request reprint Neuronal function in chronic spinal cord injury: divergence between locomotor and flexion- and H-reflex activity
    R Muller
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich, Switzerland
    Clin Neurophysiol 117:1499-507. 2006
    ..The objective of this study was to examine the behavior of locomotor EMG activity and of spinal reflexes in patients with chronic motor-complete SCI...
  29. doi request reprint Outcome after incomplete spinal cord injury: central cord versus Brown-Sequard syndrome
    M Wirz
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Spinal Cord 48:407-14. 2010
    ..A retrospective analysis of prospectively collected data...
  30. ncbi request reprint Locomotion in patients with spinal cord injuries
    V Dietz
    Swiss Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    Phys Ther 77:508-16. 1997
    ..This article reviews the pathophysiology and functional importance of increased muscle tone and the effects of treadmill training on the locomotor pattern underlying new attempts to improve the mobility of patients with paraplegia...
  31. ncbi request reprint Efficient testing of motor function in spinal cord injured rats
    G A Metz
    Brain Research Institute, University and ETH Zurich, 8057, Zurich, Switzerland
    Brain Res 883:165-77. 2000
    ..This approach should help to standardize modular testing procedures across different laboratories working on spinal cord injury...
  32. pmc Obstacle avoidance during human walking: learning rate and cross-modal transfer
    T Erni
    ParaCare, Paraplegic Centre of the University Hospital Balgrist, Zurich, Switzerland
    J Physiol 534:303-12. 2001
    ..The fact that little CMT occurs from visual to non-visual stimuli and from ACU to LED suggests that visual afferent input is processed in a different way to non-visual stimuli...
  33. ncbi request reprint Proprioception and locomotor disorders
    Volker Dietz
    ParaCare, Institute for Rehabilitation and Research, University Hospital Balgrist, Forchstrasse 340, CH 8008, Zurich, Switzerland
    Nat Rev Neurosci 3:781-90. 2002
  34. pmc Effects of body immersion on postural adjustments to voluntary arm movements in humans: role of load receptor input
    V Dietz
    Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    J Physiol 497:849-56. 1996
    ..However, because of the changed/decreased afferent input no postural adjustments are generated...
  35. ncbi request reprint Recovery from spinal cord injury--underlying mechanisms and efficacy of rehabilitation
    V Dietz
    ParaCare, Swiss Paraplegic Centre of the University Hospital Bagrlist, Zurich, Switzerland
    Acta Neurochir Suppl 89:95-100. 2004
    ..This suggests that neuronal circuits underlying 'locomotor pattern generation' in man is not restricted to any specific level of the spinal cord, but extends from thoraco-lumbal to cervical levels...
  36. ncbi request reprint Single joint perturbation during gait: neuronal control of movement trajectory
    V Dietz
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    Exp Brain Res 158:308-16. 2004
    ..This was interpreted as being directed to stabilise body equilibrium...
  37. pmc Effects of changing stance conditions on anticipatory postural adjustment and reaction time to voluntary arm movement in humans
    V Dietz
    ParaCare, Paraplegic Centre of the University Hospital Balgrist, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    J Physiol 524:617-27. 2000
    ....
  38. ncbi request reprint The influence of a clear layer on near-infrared spectrophotometry measurements using a liquid neonatal head phantom
    M Wolf
    Clinic for Neonatology, University Hospital, Zurich, Switzerland
    Phys Med Biol 44:1743-53. 1999
    ..3, 29.2, 23.4 and 16.6%. Concentration changes were underestimated by a factor of six to ten. This study demonstrates the need to develop algorithms which take into consideration anatomical structures...
  39. ncbi request reprint Spinal cord pattern generators for locomotion
    V Dietz
    ParaCare, Institute for Research and Rehabilitation, University Hospital Balgrist, Forchstr 340, 8008 Zurich, Switzerland
    Clin Neurophysiol 114:1379-89. 2003
    ..The significance of this research is in a better understanding of the pathophysiology underlying movement disorders and the consequences for an appropriate treatment...
  40. ncbi request reprint Leg muscle activation during gait in Parkinson's disease: influence of body unloading
    V Dietz
    Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    Electroencephalogr Clin Neurophysiol 105:400-5. 1997
    ..It is suggested that the latter observation is due to a change in the threshold or bias of the extensor load reflex mechanism in the patients. The slope or gain of this reflex appears to be preserved...
  41. doi request reprint Concepts of aging with paralysis: implications for recovery and treatment
    M Wirz
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Handb Clin Neurol 109:77-84. 2012
    ..In addition, problems in general health (e.g., in circulation, kidney function, diabetes mellitus) may affect the functional independence of elderly subjects with SCI...
  42. doi request reprint Neuronal dysfunction in chronic spinal cord injury
    M Hubli
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Spinal Cord 49:582-7. 2011
    ..Training of spinal interneuronal circuits including the enhancement of an appropriate afferent input might serve as an intervention to prevent neuronal dysfunction after an SCI...
  43. ncbi request reprint Driven gait orthosis for improvement of locomotor training in paraplegic patients
    G Colombo
    Rehabilitation and Research Institute ParaCare, University Hospital Balgrist, Zurich, Switzerland
    Spinal Cord 39:252-5. 2001
    ..With the driven gait orthosis training sessions can be prolonged and workload of therapists can be reduced, and therefore, the automated training represents an alternative to the conventional therapy...
  44. ncbi request reprint The effects of unilateral pyramidal tract section on hindlimb motor performance in the rat
    G A Metz
    Brain Research Institute, University and Swiss Federal Institute of Technology, Zurich, Switzerland
    Behav Brain Res 96:37-46. 1998
    ..We conclude that the possibility to correlate regenerative changes following selective pyramidal tract lesions with hindlimb function is thus limited...
  45. ncbi request reprint Obstacle avoidance during human walking: H-reflex modulation during motor learning
    F Hess
    Balgrist University Hospital, Spinal Cord Injury Center, Forchstrasse 340, CH 8008, Zurich, Switzerland
    Exp Brain Res 151:82-9. 2003
    ..The observations made are probably less specific for this motor task (stepping over the obstacle), but rather associated with the increased attention required by the motor learning task during the first obstacle run...
  46. ncbi request reprint Treadmill training of paraplegic patients using a robotic orthosis
    G Colombo
    Paraplegic Center ParaCare, University Hospital Balgrist, Zurich, Switzerland
    J Rehabil Res Dev 37:693-700. 2000
    ..With the DGO the legs of patients with different degrees of paresis and spasticity could be trained for more than half an hour, and physiological gait patterns were obtained...
  47. ncbi request reprint Improving axonal growth and functional recovery after experimental spinal cord injury by neutralizing myelin associated inhibitors
    K Fouad
    Brain Research Institute, University of Zurich and Department of Biology ETH Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
    Brain Res Brain Res Rev 36:204-12. 2001
    ..These observations, together with electrophysiological results, suggest that neuronal CNS circuits of mAb IN-1-treated animals can be rearranged, and that sprouting and regenerating axons form functionally meaningful connections...
  48. ncbi request reprint Significance of load receptor input during locomotion: a review
    V Dietz
    Swiss Paraplegic Centre, University Hospital Balgrist, Forchstr 340, CH 8008, Zurich, Switzerland
    Gait Posture 11:102-10. 2000
    ..Recent experiments in paraplegic patients show that the beneficial effects of a locomotor training critically depends on the initial degree of body unloading and reloading during the course of the training period...
  49. ncbi request reprint The influence of age on learning a locomotor task
    H J A van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, Zurich, CH 8008, Switzerland
    Clin Neurophysiol 115:2134-43. 2004
    ..The aim of this study was to evaluate differences between young and elderly subjects in the acquisition and performance of a precision locomotor task, with full and restricted vision...
  50. ncbi request reprint Impaired facilitation of motor evoked potentials in incomplete spinal cord injury
    Philipp Diehl
    Spinal Cord Injury Center, University Hospital Balgrist, Forchstrasse 340, 8008, Zurich, Switzerland
    J Neurol 253:51-7. 2006
    ..To improve the diagnosis of damaged spinal motor pathways in incomplete spinal cord injury (iSCI) by assessing the facilitation of lower limbs motor evoked potentials (MEP)...
  51. ncbi request reprint Proprioceptive input overrides vestibulo-spinal drive during human locomotion
    V Dietz
    ParaCare, University Hospital Balgrist, Forchstr. 340, , Switzerland
    Neuroreport 12:2743-6. 2001
    ..It is suggested that the amount of proprioceptive feedback from the legs determines the influence of vestibulo-spinal input on body movement...
  52. ncbi request reprint Transcutaneous functional electrical stimulation for grasping in subjects with cervical spinal cord injury
    S Mangold
    Automatic Control Laboratory, Swiss Federal Institute of Technology Zurich ETHZ, Zurich, Switzerland
    Spinal Cord 43:1-13. 2005
    ..Case series...
  53. pmc Long term effects of locomotor training in spinal humans
    M Wirz
    ParaCare, Paraplegic Centre of the University Hospital Balgrist, Forchstrasse 340, CH-8008 Zurich, Switzerland
    J Neurol Neurosurg Psychiatry 71:93-6. 2001
    ..By contrast the EMG significantly fell in those with complete SCI. The results suggest a training induced plasticity of neuronal centres in the isolated spinal cord which may be of relevance for future interventional therapies...
  54. ncbi request reprint CO2 reactivity of the cerebral hemoglobin concentration in healthy term newborns measured by near infrared spectrophotometry
    V Dietz
    Department of Neonatology, University Hospital, Zurich, Switzerland
    Biol Neonate 75:85-90. 1999
    ..As the CO2 reactivity might be an indicator for infants at risk of cerebral damage, it is necessary to have data on the physiological range of this parameter...
  55. ncbi request reprint Influence of vestibular and visual stimulation on split-belt walking
    B Marques
    Neurology Department, Zurich University Hospital, Frauenklinikstrasse 26, 8091, Zurich, Switzerland
    Exp Brain Res 183:457-63. 2007
    ..The missing effect during fast walking corroborates the findings by others that the influence of vestibular tone asymmetry on locomotion decreases at higher gait velocities...
  56. ncbi request reprint Do human bipeds use quadrupedal coordination?
    Volker Dietz
    ParaCare, Institute for Rehabilitation and Research, University Hospital Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland
    Trends Neurosci 25:462-7. 2002
    ..The persistence of such movement control has consequences for rehabilitation and the applicability of animal research to human patients with spinal cord injury...
  57. ncbi request reprint Locomotor activity in spinal cord-injured persons
    V Dietz
    Spinal Chord Injury Center, University Hospital Balgrist, 8008 Zurich, Switzerland
    J Appl Physiol 96:1954-60. 2004
    ..In the future, if regeneration approaches can successfully be applied in human SCI, even individuals with complete SCI may recover walking ability with locomotor training...
  58. ncbi request reprint Lumbar spinal stenosis: assessment of cauda equina involvement by electrophysiological recordings
    D Egli
    Spinal Cord Injury Center, University Hospital Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland
    J Neurol 254:741-50. 2007
    ..All patients were assessed by neurological examination, electrophysiological recordings, and magnetic resonance imaging (MRI) of the lumbar spine. The electrophysiological recordings focused on spinal lumbar nerve involvement...
  59. doi request reprint Behavior of spinal neurons deprived of supraspinal input
    Volker Dietz
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich, Switzerland
    Nat Rev Neurol 6:167-74. 2010
    ..Appropriate training and/or provision of afferent input to spinal neurons might help to prevent neuronal dysfunction in chronic SCI...
  60. ncbi request reprint Changes in activity after a complete spinal cord injury as measured by the Spinal Cord Independence Measure II (SCIM II)
    Brigitte Wirth
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Neurorehabil Neural Repair 22:145-53. 2008
    ..The Spinal Cord Independence Measure II (SCIM II) is an independence scale that was specifically developed for subjects with SCI. However, little is known about the changes in SCIM II scores during and after rehabilitation...
  61. doi request reprint Obstacle stepping in patients with Parkinson's disease. Complexity does influence performance
    Jan Michel
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, 8008, Zurich, Switzerland
    J Neurol 256:457-63. 2009
    ..The present results extend findings from upper to lower limb movements, namely that PD subjects have difficulties in the performance of bilateral motor tasks...
  62. doi request reprint Walking during daily life can be validly and responsively assessed in subjects with a spinal cord injury
    Hubertus J A van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital Zurich, Switzerland
    Neurorehabil Neural Repair 23:117-24. 2009
    ..This study assessed the validity and responsiveness of the Spinal Cord Independence Measure (SCIM II) items indoor mobility, mobility for moderate distances, and outdoor mobility...
  63. ncbi request reprint Changes in activity after a complete spinal cord injury as measured by the Spinal Cord Independence Measure II (SCIM II)
    Brigitte Wirth
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Neurorehabil Neural Repair 22:279-87. 2008
    ..The Spinal Cord Independence Measure II (SCIM II) is an independence scale that was specifically developed for subjects with SCI. However, little is know about the changes in SCIM II scores during and after rehabilitation...
  64. ncbi request reprint The amplitude of lower leg motor evoked potentials is a reliable measure when controlled for torque and motor task
    Hubertus J A van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, 8008, Zurich, Switzerland
    J Neurol 254:1089-98. 2007
    ..The study investigated the reliability of anterior tibial (TA) MEP measures controlled for dorsal flexion torque and motor task...
  65. doi request reprint Nogo-A antibodies and training reduce muscle spasms in spinal cord-injured rats
    Roman R Gonzenbach
    Brain Research Institute, University of Zurich, Winterthurerstrasse 190, Zurich, Switzerland
    Ann Neurol 68:48-57. 2010
    ....
  66. doi request reprint Recent advances in spinal cord neurology
    Volker Dietz
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstr 340, 8008, Zurich, Switzerland
    J Neurol 257:1770-3. 2010
    ..A focus of the review concerns the debate about the significance of translational medicine in spinal cord injury with the introduction of new drugs directed to achieve some spinal cord repairs...
  67. ncbi request reprint Contribution of feedback and feedforward strategies to locomotor adaptations
    Tania Lam
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    J Neurophysiol 95:766-73. 2006
    ..In summary, adaptive changes in the walking pattern were driven by both feedback and feedforward adjustments in the walking pattern appropriate for overcoming the effects of resistance...
  68. doi request reprint Rehabilitation of locomotion after spinal cord injury
    Hubertus J A van Hedel
    SCI Research, Spinal Cord Injury Center, University of Zurich, Balgrist University Hospital, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    Restor Neurol Neurosci 28:123-34. 2010
    ....
  69. ncbi request reprint Effectiveness of automated locomotor training in patients with chronic incomplete spinal cord injury: a multicenter trial
    Markus Wirz
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Arch Phys Med Rehabil 86:672-80. 2005
    ..To determine whether automated locomotor training with a driven-gait orthosis (DGO) can increase functional mobility in people with chronic, motor incomplete spinal cord injury (SCI)...
  70. ncbi request reprint Muscle force and gait performance: relationships after spinal cord injury
    Markus Wirz
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Arch Phys Med Rehabil 87:1218-22. 2006
    ....
  71. ncbi request reprint Learning a high-precision locomotor task in patients with Parkinson's disease
    Hubertus J A van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Mov Disord 21:406-11. 2006
    ..Restricting vision deteriorated performance in both groups. The similar performance of PD patients after task repetition might indicate that adequate training could improve adaptive locomotor behavior in PD patients...
  72. ncbi request reprint Obstacle avoidance during human walking: effects of biomechanical constraints on performance
    Hubertus J van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, Ch 8008 Zurich, Switzerland
    Arch Phys Med Rehabil 85:972-9. 2004
    ..To determine whether fixation of the ankle joint, the knee joint, or both increasingly affects the performance of a newly learned task, that is, stepping over an obstacle...
  73. ncbi request reprint Assessment of walking speed and distance in subjects with an incomplete spinal cord injury
    Hubertus J A van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Neurorehabil Neural Repair 21:295-301. 2007
    ..Studies about testing preferred and maximum speeds in subjects with incomplete spinal cord injury are lacking...
  74. doi request reprint The occurrence of the Babinski sign in complete spinal cord injury
    Jens A Petersen
    Spinal Cord Injury Center, University Hospital Balgrist, Zurich, Switzerland
    J Neurol 257:38-43. 2010
    ..In complete SCI subjects, the occurrence of the BS is connected with spastic muscle tone. The absence of the BS is frequently due to associated peripheral nerve damage...
  75. doi request reprint Locomotion in stroke subjects: interactions between unaffected and affected sides
    Evelyne Kloter
    Spinal Cord Injury Centre, Balgrist University Hospital, Forchstr 340, Ch 8008 Zurich, Switzerland
    Brain 134:721-31. 2011
    ..These observations indicate strong mutual influences between unaffected and affected sides during locomotion of post-stroke subjects, which might be used to optimize rehabilitation approaches...
  76. ncbi request reprint Gait disorder in spasticity and Parkinson's disease
    V Dietz
    Department of Paraplegiology, University of Zurich, Switzerland
    Adv Neurol 87:143-54. 2001
    ..Consequently, physiotherapeutic approaches should be applied primarily and antispastic drug therapy secondarily in mobile patients; whereas antispastic drugs may relieve muscle spasms and improve nursing care in immobilized patients...
  77. ncbi request reprint Neurophysiology of gait disorders: present and future applications
    V Dietz
    Swiss Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    Electroencephalogr Clin Neurophysiol 103:333-55. 1997
    ..In the future, the knowledge gained from gait analysis may help in the selection of the appropriate pharmacological and physical treatment required even though the patient may only be at an early stage of motor impairment...
  78. ncbi request reprint Providing the clinical basis for new interventional therapies: refined diagnosis and assessment of recovery after spinal cord injury
    A Curt
    Spinal Cord Injury Centre, University Hospital Balgrist, Switzerland
    Spinal Cord 42:1-6. 2004
    ..The project's aim is to establish objective, refined tools as a basis for monitoring the effects of new treatment strategies...
  79. ncbi request reprint New technologies and concepts for rehabilitation in the acute phase of stroke: a collaborative matrix
    E M Siekierka
    Department of Neurology, University Hospital Zurich, Zurich, Switzerland
    Neurodegener Dis 4:57-69. 2007
    ..We also outline the neuroscientific basis of our approach, present our detailed clinical assessment protocol and provide preliminary results from patient testing of each of the three systems showing their viability for patient use...
  80. pmc Spinal cord lesion: effects of and perspectives for treatment
    V Dietz
    ParaCare, Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    Neural Plast 8:83-90. 2001
    ..The pathophysiology and functional significance of spastic muscle tone and the effects of treadmill training on the locomotor pattern underlying new attempts to improve the mobility of patients with paraplegia are reviewed...
  81. pmc Obstacle avoidance during human walking: transfer of motor skill from one leg to the other
    H J A van Hedel
    ParaCare, Institute for Rehabilitation and Research at the University Hospital Balgrist, Zurich, Switzerland
    J Physiol 543:709-17. 2002
    ..It is hypothesised that the learning effects observed in the present experiments are mediated at a higher level (e.g. brainstem) of locomotor control...
  82. ncbi request reprint Socio-economic outcome of paraplegia compared to lower limb amputation
    A Cavigelli
    ParaCare, Paraplegic Centre, University Hospital Balgrist, Zurich, Switzerland
    Spinal Cord 40:174-7. 2002
    ..The socio-economic outcome was retrospectively compared between patients with traumatic lower limb amputation and those with paraplegia due to a spinal cord injury (SCI)...
  83. ncbi request reprint Standardized assessment of walking capacity after spinal cord injury: the European network approach
    H J A van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Neurol Res 30:61-73. 2008
    ..Then, we investigated which categories of the WISCI II apply to SCI subjects who participated in the European Multicenter Study of Human Spinal Cord Injury (EM-SCI), and the relationship between the 10MWT and the TUG...
  84. doi request reprint Difficulty of elderly SCI subjects to translate motor recovery--"body function"--into daily living activities
    Werner Jakob
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    J Neurotrauma 26:2037-44. 2009
    ..Therefore, rehabilitation approaches in elderly subjects should focus on functional training...
  85. doi request reprint Levodopa therapy in incomplete spinal cord injury
    Oliver Maric
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    J Neurotrauma 25:1303-7. 2008
    ..The combination of L-Dopa and physiotherapy had no greater effect on the outcome than placebo and physiotherapy. The possible reasons for the different effect of L-Dopa in stroke and iSCI subjects are discussed...
  86. doi request reprint Computerized visual feedback: an adjunct to robotic-assisted gait training
    Raphael Banz
    Spinal Cord Injury Research, Balgrist University Hospital, Zurich, Switzerland
    Phys Ther 88:1135-45. 2008
    ....
  87. ncbi request reprint Assessing walking ability in subjects with spinal cord injury: validity and reliability of 3 walking tests
    Hubertus J van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Arch Phys Med Rehabil 86:190-6. 2005
    ..To assess the validity and reliability of 3 timed walking tests (Timed Up & Go [TUG], 10-meter walk test [10MWT], 6-minute walk test) in subjects with spinal cord injury (SCI)...
  88. ncbi request reprint Magnetic stimulation of sacral roots for assessing the efferent neuronal pathways of lower urinary tract
    Biljana Rodic
    ParaCare, Institute for Rehabilitation and Research, University Hospital Balgrist, Zurich, Switzerland
    Muscle Nerve 26:486-91. 2002
    ..The method of SMS may be helpful for the evaluation of cases in which urodynamic studies remain inconclusive...
  89. ncbi request reprint Differential effect of spinal cord injury and functional impairment on human brain activation
    A Curt
    ParaCare, Institute for Rehabilitation and Research, University Hospital Balgrist, Zurich, Switzerland
    J Neurotrauma 19:43-51. 2002
    ..The effect of impaired afferent feedback and/or increased compensatory use of non-impaired limbs in SCI patients needs further evaluation...
  90. ncbi request reprint Locomotor activity in spinal man: significance of afferent input from joint and load receptors
    Volker Dietz
    Paraplegic Centre of the University Hospital Balgrist, Zurich, Switzerland
    Brain 125:2626-34. 2002
    ..This is in line with observations from infant stepping experiments and experiments in cats. Afferent feedback from knee and ankle joints may be involved largely in the control of focal movements...
  91. ncbi request reprint Transfer of motor performance in an obstacle avoidance task to different walking conditions
    Tania Lam
    Spinal Cord Injury Center, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich, Switzerland
    J Neurophysiol 92:2010-6. 2004
    ..The results are discussed in the context of emerging concepts in the neural control of walking and motor learning...
  92. ncbi request reprint Repair of the injured spinal cord. A joint approach of basic and clinical research
    Anita D Buchli
    Brain Research Institute, University and ETH Zurich, Zurich, Switzerland
    Neurodegener Dis 4:51-6. 2007
    ....
  93. doi request reprint Gait disorders
    V Dietz
    Balgrist University Hospital, Zurich, Switzerland
    Handb Clin Neurol 110:133-43. 2013
    ..Therapy should be directed toward functional training, which takes advantage of the plasticity of the nervous system. In the future a combination of repair and functional training will further improve the mobility of disabled patients...
  94. ncbi request reprint Tissue oxygen saturation measured by near infrared spectrophotometry correlates with arterial oxygen saturation during induced oxygenation changes in neonates
    M Wolf
    Clinic for Neonatology, University Hospital, Zurich, Switzerland
    Physiol Meas 21:481-91. 2000
    ..TOSa quantified changes reasonably correctly: delta TOSa = 0.90 delta SaO2. Changes in TOSc and TOSa were highly correlated (r2 = 0.98). These results are promising, but the large inter-individual variation requires further work...
  95. doi request reprint Neuropathic pain in spinal cord injury: significance of clinical and electrophysiological measures
    Susanne Wydenkeller
    Spinal Cord Injury Center, University Hospital Balgrist, Zurich, Forchstrasse 340, 8008 Zurich, Switzerland
    Eur J Neurosci 30:91-9. 2009
    ..These findings could be helpful for both the development of an objective diagnosis of bNP and for testing the effectiveness of new therapeutic agents...
  96. pmc SSEP analysis in surgery of idiopathic scoliosis: the influence of spine deformity and surgical approach
    Oliver Hausmann
    ParaCare, Swiss Paraplegic Center, Institute for Rehabilitation and Research, University Hospital Balgrist, Forchstrasse 340, 8008 Zurich, Switzerland
    Eur Spine J 12:117-23. 2003
    ..Even in clinically uneventful surgery, the postoperative t-SSEPs can be deteriorated depending on the surgical approach. This indicates a subclinical impact of spine surgery upon spinal cord function...
  97. ncbi request reprint Phase-dependent modulation of short latency cutaneous reflexes during walking in man
    Bernke Christianne Maria Baken
    SMK Research, Sint Maartens Hospital, Nijmegen, The Netherlands
    Brain Res 1031:268-75. 2005
    ..It is concluded that P1 and P2 reflexes can appear independently from each other, but that their modulation in the step cycle is mostly quite similar in some phases of the step cycle (end swing)...
  98. ncbi request reprint Patient-cooperative strategies for robot-aided treadmill training: first experimental results
    Robert Riener
    Rehabilitation Engineering Group, Automatic Control Laboratory, Swiss Federal Institute of Technology ETH, CH 8092 Zurich, Switzerland
    IEEE Trans Neural Syst Rehabil Eng 13:380-94. 2005
    ..Further improvements of the technical design and additional clinical testing is required to prove whether the therapeutic outcome can be enhanced by such cooperative strategies...
  99. ncbi request reprint Letter to the editor
    Edelle C Field-Fote
    Neurorehabil Neural Repair 20:233; author reply 233-4. 2006
  100. ncbi request reprint Electromyographic activity associated with spontaneous functional recovery after spinal cord injury in rats
    Sibille Kaegi
    Brain Research Institute, University of Zurich and Department of Biology ETH Zurich, 8057 Zurich, Switzerland
    Eur J Neurosci 16:249-58. 2002
    ..Activity overlap between flexor and extensor muscles might be directly caused by altered descending input or by maladaptation of central pattern generating networks and/or sensory feedback...
  101. pmc Single joint perturbation during gait: preserved compensatory response pattern in spinal cord injured subjects
    Edelle C Field-Fote
    The Miami Project to Cure Paralysis, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Clin Neurophysiol 118:1607-16. 2007
    ..The study aim was to examine whether supraspinal influences affect the behavior of complex electromyographic (EMG) responses to single limb perturbations during walking...