Larissa Sweeny

Summary

Publications

  1. pmc CD147 and AGR2 expression promote cellular proliferation and metastasis of head and neck squamous cell carcinoma
    Larissa Sweeny
    Department of Surgery, University of Alabama, Division of Otolaryngology Head and Neck Surgery, Birmingham, Alabama, USA
    Exp Cell Res 318:1788-98. 2012
  2. ncbi request reprint Head and neck cutaneous squamous cell carcinoma requiring parotidectomy: prognostic indicators and treatment selection
    Larissa Sweeny
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Otolaryngol Head Neck Surg 150:610-7. 2014
  3. pmc Assessment and incidence of salivary leak following laryngectomy
    Hilliary N White
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Laryngoscope 122:1796-9. 2012
  4. pmc Use of recombinant bone morphogenetic protein 2 in free flap reconstruction for osteonecrosis of the mandible
    Larissa Sweeny
    National Institutes of Health Research Fellow, Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, AL 35294 0012, USA
    J Oral Maxillofac Surg 70:1991-6. 2012
  5. pmc CD147 expression in advanced cutaneous squamous cell carcinoma
    Larissa Sweeny
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Alabama at Birmingham, AL 35233, USA
    J Cutan Pathol 39:603-9. 2012
  6. pmc Use of panitumumab-IRDye800 to image cutaneous head and neck cancer in mice
    C Hope Heath
    Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294 0012, USA
    Otolaryngol Head Neck Surg 148:982-90. 2013
  7. pmc Outcomes in head and neck reconstruction by surgical site and donor site
    John W Frederick
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Laryngoscope 123:1612-7. 2013
  8. pmc Evaluation of tyrosine receptor kinases in the interactions of head and neck squamous cell carcinoma cells and fibroblasts
    Larissa Sweeny
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    Oral Oncol 48:1242-9. 2012
  9. pmc Inhibition of fibroblasts reduced head and neck cancer growth by targeting fibroblast growth factor receptor
    Larissa Sweeny
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Laryngoscope 122:1539-44. 2012
  10. pmc Fibroblast growth factor receptor mediates fibroblast-dependent growth in EMMPRIN-depleted head and neck cancer tumor cells
    Zhiyong Liu
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, USA
    Mol Cancer Res 9:1008-17. 2011

Collaborators

Detail Information

Publications21

  1. pmc CD147 and AGR2 expression promote cellular proliferation and metastasis of head and neck squamous cell carcinoma
    Larissa Sweeny
    Department of Surgery, University of Alabama, Division of Otolaryngology Head and Neck Surgery, Birmingham, Alabama, USA
    Exp Cell Res 318:1788-98. 2012
    ..In vitro, knockdown of CD147 or AGR2 decreased cellular proliferation, migration and invasion. In vivo, knockdown of CD147 or AGR2 expression decreased primary tumor growth as well as regional and distant metastasis...
  2. ncbi request reprint Head and neck cutaneous squamous cell carcinoma requiring parotidectomy: prognostic indicators and treatment selection
    Larissa Sweeny
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Otolaryngol Head Neck Surg 150:610-7. 2014
    ..Evaluate characteristics and risk factors for patients with advanced cutaneous squamous cell carcinoma (cSCC)...
  3. pmc Assessment and incidence of salivary leak following laryngectomy
    Hilliary N White
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Laryngoscope 122:1796-9. 2012
    ..To determine the incidence and risk factors of pharyngocutaneous fistula formation in patients undergoing either primary or salvage laryngectomies and evaluate the role of barium esophagram in these patients...
  4. pmc Use of recombinant bone morphogenetic protein 2 in free flap reconstruction for osteonecrosis of the mandible
    Larissa Sweeny
    National Institutes of Health Research Fellow, Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, AL 35294 0012, USA
    J Oral Maxillofac Surg 70:1991-6. 2012
    ..The purpose of this study is to determine whether the addition of rhBMP-2 at the union of vascularized bone and native bone improves surgical outcomes in patients with osteonecrosis of the mandible...
  5. pmc CD147 expression in advanced cutaneous squamous cell carcinoma
    Larissa Sweeny
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Alabama at Birmingham, AL 35233, USA
    J Cutan Pathol 39:603-9. 2012
    ..Our purpose was to evaluate the expression patterns of CD147 and related monocarboxylate transporters (MCT1, MCT4) to determine their correlation with survival...
  6. pmc Use of panitumumab-IRDye800 to image cutaneous head and neck cancer in mice
    C Hope Heath
    Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294 0012, USA
    Otolaryngol Head Neck Surg 148:982-90. 2013
    ..To assess the feasibility of panitumumab in real-time fluorescent imaging and histologic processing of cutaneous squamous cell carcinoma (cSCC) in mice...
  7. pmc Outcomes in head and neck reconstruction by surgical site and donor site
    John W Frederick
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Laryngoscope 123:1612-7. 2013
    ..Define surgical outcomes of specific donor sites for free tissue transfer in head and neck reconstruction...
  8. pmc Evaluation of tyrosine receptor kinases in the interactions of head and neck squamous cell carcinoma cells and fibroblasts
    Larissa Sweeny
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    Oral Oncol 48:1242-9. 2012
    ..In this article, we investigated the role of several receptor tyrosine kinases (RTKs) in the interactions between HNSCC cells and supporting cells (fibroblasts)...
  9. pmc Inhibition of fibroblasts reduced head and neck cancer growth by targeting fibroblast growth factor receptor
    Larissa Sweeny
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Laryngoscope 122:1539-44. 2012
    ..We further investigated these relationships by suppressing stromal cell growth through the inhibition of fibroblast growth factor receptor (FGFR)...
  10. pmc Fibroblast growth factor receptor mediates fibroblast-dependent growth in EMMPRIN-depleted head and neck cancer tumor cells
    Zhiyong Liu
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, USA
    Mol Cancer Res 9:1008-17. 2011
    ..Taken together, these results suggest that EMMPRIN acquired during tumor progression promotes fibroblast-independent tumor growth...
  11. pmc Reconstruction of scalp defects with the radial forearm free flap
    Larissa Sweeny
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Alabama, USA
    Head Neck Oncol 4:21. 2012
    ..This study evaluates various microvascular free flap reconstructions in this patient population, including the rarely utilized radial forearm free flap...
  12. pmc Microvascular anastomotic coupler assessment in head and neck reconstruction
    John W Frederick
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35294 0012, USA
    Otolaryngol Head Neck Surg 149:67-70. 2013
    ..To assess the advantages of using mechanical anastomotic systems in head and neck free tissue transfer...
  13. pmc EGFR expression in advanced head and neck cutaneous squamous cell carcinoma
    Larissa Sweeny
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Head Neck 34:681-6. 2012
    ..The significance of epidermal growth factor receptor (EGFR) expression in advanced cutaneous squamous cell carcinoma (SCC) of the head and neck remains poorly understood...
  14. pmc Preclinical comparison of near-infrared-labeled cetuximab and panitumumab for optical imaging of head and neck squamous cell carcinoma
    Kristine E Day
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Volker Hall G082, 1670 University Blvd, Birmingham, AL, 35233, USA
    Mol Imaging Biol 15:722-9. 2013
    ..The present study aimed to compare two fluorescently labeled anti-epidermal growth factor receptor (EGFR) antibodies for detection of head and neck squamous cell carcinoma (HNSCC)...
  15. pmc Bone morphogenetic protein 6 expression in oral cavity squamous cell cancer is associated with bone invasion
    Alexandra E Kejner
    Department of Otolaryngology, University of Alabama Birmingham, Birmingham, Alabama, U S A
    Laryngoscope 123:3061-5. 2013
    ..To evaluate bone invasion, survival, and expression of bone morphogenetic protein-6 (BMP-6) in oral cavity cancer in the context of known biomarkers indicative of poor prognosis...
  16. pmc A novel extracellular drug conjugate significantly inhibits head and neck squamous cell carcinoma
    Larissa Sweeny
    University of Alabama at Birmingham, Department of Surgery, Division of Otolaryngology Head and Neck Surgery, 1670 University Boulevard, Volker Hall G082, Birmingham, AL 35233, USA
    Oral Oncol 49:991-7. 2013
    ..In this study, EDC22's potential as a treatment modality for HNSCC was performed...
  17. pmc Use of panitumumab-IRDye800 to image microscopic head and neck cancer in an orthotopic surgical model
    C Hope Heath
    Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA
    Ann Surg Oncol 19:3879-87. 2012
    ..This study sought to determine if this imaging system was capable of detecting micrometastatic head and neck squamous cell carcinoma (HNSCC) in preclinical models...
  18. pmc Incidence and outcomes of stricture formation postlaryngectomy
    Larissa Sweeny
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Otolaryngol Head Neck Surg 146:395-402. 2012
    ..Postlaryngectomy stricture formation and dysphagia negatively affect quality of life and result in nutritional compromise. Understanding risk factors and successful treatment strategies may improve treatment outcomes...
  19. pmc Assessment of tissue autofluorescence and reflectance for oral cavity cancer screening
    Larissa Sweeny
    Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Otolaryngol Head Neck Surg 145:956-60. 2011
    ..There is limited published evidence regarding the efficacy of these devices. The authors investigated the sensitivity and specificity of these modalities compared with standard examination...
  20. pmc Outcomes of recurrent head and neck cutaneous squamous cell carcinoma
    Nichole R Dean
    Division of Otolaryngology, Head and Neck Surgery, Department of Surgery, The University of Alabama at Birmingham, Volker Hall G082, 1670 University Boulevard, Birmingham, AL 35233, USA
    J Skin Cancer 2011:972497. 2011
    ..001). Adjuvant postoperative radiotherapy did not improve overall survival (P = .42). Overall survival was poor for patients with advanced recurrent cSCC despite the combined treatment with surgery and radiotherapy...
  21. doi request reprint Social networking and professionalism in otolaryngology residency applicants
    J Blake Golden
    the Division of Otolaryngology Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Laryngoscope 122:1493-6. 2012
    ..To assess compliance with Accreditation Council for Graduation Medical Education standards of professionalism among otolaryngology residency applicants with publicly searchable Facebook profiles...